ライフサイエンスコーパス: counterregulation

1 ring hypoglycemic clamps identified impaired counterregulation.

2 ucose turnover as indicators of hypoglycemia counterregulation.

3 e indolamine 2,3-dioxygenase (IDO) in immune counterregulation.

4 in diabetic patients with defective glucose counterregulation.

5 were monitored to elucidate the mechanism of counterregulation.

6 and diabetic BB rats with defective hormonal counterregulation.

7 due to diabetes-associated loss of IL-1beta counterregulation.

8 sult in a marked stimulus to hepatic glucose counterregulation.

9 efore could contribute to defects in glucose counterregulation.

10 iabetes and contributes to defective glucose counterregulation.

11 st 30 min of the clamp), reflecting impaired counterregulation.

12 may play an important role in human glucose counterregulation.

13 the kidney is also involved in human glucose counterregulation.

14 kidney may play an important role in glucose counterregulation.

15 it is a key glucose sensor for hypoglycemic counterregulation.

16 We conclude that impaired counterregulation after chronic hypoglycemia may result

17 stress system response, (2) its capacity for counterregulation after danger has passed and (3) the ph

18 ole in the pathogenesis of defective glucose counterregulation and hypoglycemia unawareness and thus

19 diabetes (T1D) may exhibit defective glucose counterregulation and impaired hypoglycemia symptom reco

20 , P < 0.001), suggesting more potent glucose counterregulation and improved recovery from hypoglycemi

21 unawareness and, in part, defective glucose counterregulation and the unifying concept of hypoglycem

22 entral mechanism underlying LX-driven immune counterregulation, and a hitherto unappreciated mechanis

23 IGFBP-1 contributes to glucose counterregulation, and observational studies demonstrate

24 lipoxins (LXs) that stereoselectively signal counterregulation, as well as potential deleterious acti

25 n is a multigenic disorder in which abnormal counterregulation between dopamine and Ang II plays a ro

26 otype in barrier-defective skin is shaped by counterregulation between the TSLP/type 2 and IL-23/type

27 Importantly, we reveal a counterregulation between these 2 inflammatory axes.

28 n rate would be augmented and neuro-hormonal counterregulation blunted during hypoglycaemia when the

29 To determine whether counterregulation by interleukin (IL)-10 plays a role in

30 ndicate that the restoration of hypoglycemic counterregulation by pancreas transplantation remains st

31 might drive AD in children and that reduced counterregulation by TH1 T cells might contribute to exc

32 c hypoglycemia causes both defective glucose counterregulation (by reducing the epinephrine response

33 To evaluate the mechanisms of defective counterregulation caused by iatrogenic hypoglycemia and

34 e N+ group exhibited unimpaired hypoglycemia counterregulation, characterized by appropriate increase

35 Impaired counterregulation during hypoglycemia in type 1 diabetes

36 Impaired glucose counterregulation during hypoglycemia is well documented

37 type 1 diabetes, despite some activation of counterregulation, hypoglycemia failed to stimulate hepa

38 prior studies have not examined hypoglycemic counterregulation in any pancreas transplant recipient o

39 ess to hypoglycemia contributes to defective counterregulation in diabetes.

40 monal activation and augmentation of glucose counterregulation in humans.

41 Impairment of hypoglycemic counterregulation in intensively treated type 1 diabetes

42 ic islet transplantation can restore glucose counterregulation in long-standing T1D and support its c

43 tribute to pathogenesis of defective glucose counterregulation in response to a standard hypoglycemic

44 n acute infusion of fructose on hypoglycemia counterregulation in seven lean nondiabetic subjects.

45 etermine whether restoration of hypoglycemic counterregulation is maintained over a prolonged period

46 during acute hypoglycemia, and its effect on counterregulation may be mediated by changes in glutamat

47 rine-threonine protein kinase Akt in insulin counterregulation mirrors the central role of protein ki

48 in skeletal muscle and whether hypoglycemia counterregulation modulates insulin and catecholamine si

49 , but the molecular mechanism(s) of how this counterregulation occurs is unknown.

50 cept that generation of ROS is essential for counterregulation of acute lung inflammation.

51 A/S346A) within this motif abolishes insulin counterregulation of beta-adrenergic stimulation of cycl

52 The counterregulation of catecholamine action by insulin inc

53 Chronic activation of T cells induces counterregulation of CD28 and CD56 expression.

54 These data suggest that counterregulation of FcepsilonRI and TLR-7 pathways exis

55 DCs; and 3) to determine whether evidence of counterregulation of FcepsilonRIalpha and IFN-alpha path

56 Liver glycogen is important for the counterregulation of hypoglycemia and is reduced in indi

57 oncept by testing the hypothesis that during counterregulation of hypoglycemia in patients with type

58 e that these PTPases are responsible for the counterregulation of insulin signaling there, whereas bo

59 everal PTPases thought to be involved in the counterregulation of insulin signaling.

60 lucose-transporter activity and recruitment, counterregulation of lipolysis, and activation of glycog

61 Downstream of SHP1 and SYK-dependent counterregulation of MyD88 tyrosine phosphorylation, we

62 Evidence for counterregulation of NF-kappaB by RvD3 and AT-RvD3 was s

63 The molecular mechanisms involved in the counterregulation of PGI(2)/TxA(2) signaling are unclear

64 /S473A), in contrast, abolishes both insulin counterregulation of the cyclic AMP response as well as

65 Defective counterregulation results to a large extent from prior e

66 Recent studies suggest that this counterregulation results, at least in part, from regula

67 ontribute to the alterations in hypoglycemia counterregulation seen in diabetic patients during inten

68 factors that may contribute to the defective counterregulation seen in such patients.

69 loss may contribute to the impaired glucose counterregulation seen in type 1 diabetes.

70 These mutant mice also present a defective counterregulation to hypoglycemia with altered glucagon

71 2 antagonist (SSTR2a) should improve hormone counterregulation to hypoglycemia.

72 ether norepinephrine acts to promote glucose counterregulation via specific VMH beta-adrenergic recep

73 Clear evidence of hypoglycemic physiological counterregulation was first demonstrated between 75 mg/d

74 catecholaminergic responses without systemic counterregulation, we infused graded concentrations of t

75 during hypoglycemia suppresses symptoms and counterregulation while preserving cognitive function.