ライフサイエンスコーパス: covering

1 ch resulted in an incomplete aneurysmal neck covering.

2 For the larger 2 of the 3 releases (covering 0.97 km2 and 0.52 km2), we observed slow but st

3 ly and to compare them with those induced by covering 1 eye and with strategies used to recover fusio

4 n was indistinguishable from that induced by covering 1 eye.

5 n during the non-breeding season was 743 km, covering 10-20% of the maximum width of Africa/South Ame

6 more extensive than previously appreciated, covering 100% of the genome; contributions from xenotrop

7 Starbucks ranked first in downtown, covering 110 OHCAs.

8 g, we tested 54,003 coding-sequence variants covering 13,715 human genes in up to 72,868 patients wit

9 ousehold surveys, 553 passed quality checks, covering 133 countries between 1984 and 2015.

10 Enteritidis) infection covering 15 years in an interleukin (IL)-12 beta-1 recep

11 NP markers were mapped on 12 linkage groups, covering 1622 cM.

12 SPR-Cas9 genome wide arrayed sgRNA libraries covering 17,166 human and 20,430 mouse genes at a comple

13 tabase Resource is a collection of databases covering 170+ eukaryotic pathogens (protists & fungi), a

14 statistical modeling on a regional database covering 179 locations and six ecosystem types across Sc

15 y curated nonredundant phosphorylation sites covering 18,610 proteins.

16 GBD 2013 includes an annual assessment covering 188 countries from 1990 to 2013.

17 Twenty one publications covering 19 studies were included.

18 used transplantable model of ovarian cancer, covering 194,000 exomes at a mean depth of 400x with 90%

19 We included data from 145 studies covering 2.1 million participants.

20 no PrEP, unprioritized scale-up of RVP PrEP covering 2.5%-15% of adults prevented up to 9% of new in

21 ray comparative genomic hybridization (aCGH) covering 20 genes that encode intraflagellar transport (

22 ke feature is composed of a warm, dark floor covering 21,500 square kilometres surrounding a much coo

23 gs covering 6-10% of the land area, and fens covering 21-53%.

24 In 2003, grids of seabed markers, covering 225 m(2) , were established, surveyed and repla

25 Samplers were deployed at five depths covering 26-2535 m in the northern Atlantic and Tropical

26 previous review and 172 additional studies, covering 27 high-income and seven middle-income countrie

27 Tim Hortons ranked first in Toronto, covering 286 OHCAs.

28 ment in 7 independent breast cancer datasets covering 3,430 patients.

29 Synchronized haustral pressure waves, covering 3-5 cm of the colon occurred to create a charac

30 ury consisting of a dorsal scald burn injury covering 30% of total body surface area.

31 ssments for 188 countries from 1990 to 2013, covering 306 diseases and injuries, 1233 sequelae, and 7

32 .3 mV (0.19-0.33), with nonconducting tissue covering 33+/-9% of the mapped surface.

33 8,794 pediatric patients receiving treatment covering 346,277 patient-attributed months during the st

34 atic tissue in 3 separate tissue microarrays covering 38 patients.

35 The screen covering 45 of the 55 human RTKs identified 12 new as we

36 vertebrate species from zebrafish to humans covering 450 million years of evolution.

37 ve analyzed RNA-Seq data of the TCGA project covering 4569 patients in 23 cancer types using two reli

38 In a survey covering 4606 samples from 19 cancer types, and integrat

39 Using 835 inventories covering 4660 species of woody plants, we show marked fl

40 es a novel data set spanning 2605 viral OGs, covering 5228 proteins from 352 viral proteomes.

41 of the northern Alberta landscape, with bogs covering 6-10% of the land area, and fens covering 21-53

42 imated rainfall erosivity for 3,625 stations covering 63 countries.

43 Data were available for 1 238 188 patients, covering 64 National Health Service provider trusts (93%

44 In transgenic experiments covering 69% of the available sequence variation in two

45 ions have been quality evaluated and entered covering 70 PFS or their botanical ingredients.

46 nerated transcriptomes and 88 other datasets covering 70% of eudicot orders.

47 ined 724 healthcare and postal staff members covering 72% of districts.

48 cks associated with 392 traits and diseases, covering 73.9 Mb (2.2%) of the human genome.

49 dical Outcomes Study Short Form-36 (36 items covering 8 dimensions of health status as well as physic

50 ified approximately 800 hybrid-prone regions covering 8% of the genome.

51 thout CMV viremia by using a microarray chip covering 847 hsa-miRNAs.

52 tion models by means of an election data set covering 86 countries and more than 500 elections, and a

53 r scans, comprising 600 x 80 axial scans and covering a 1.5 x 2-mm2 area centered at the optic disc.

54 of over 2000 individually identified animals covering a 14-year period after the first confirmatory d

55 cipants underwent OCTA imaging of the macula covering a 3 x 3-mm area using OCTA software (Cirrus 500

56 ing using an optical microangiography system covering a 6.7 x 6.7-mm2 area centered at the optic nerv

57 ontrol and adjust the membrane tension sigma covering a broad regime.

58 sa-pastoris genome and a transcriptome atlas covering a broad sample of organs and developmental stag

59 integral part of population genetic studies covering a broad spectrum of taxa including humans.

60 btained through a rational design stratagem, covering a broad wavelength range from the UV to the NIR

61 ologically acquired samples from 22 patients covering a cumulative observation time of 75 years MDS d

62 xygen profiles at a subcentimeter resolution covering a depth of up to one meter.

63 small domains of a few atom layer thickness covering a fraction of the surface of the Ni-rich partic

64 consisting of a planar dielectric waveguide covering a gold nanostripe array fabricated on a gold fi

65 rkers and determining etiology of disease by covering a greater portion of the lipidome and using ann

66 gral part of the catalytic domain structure, covering a hydrophobic patch on the catalytic AA9 module

67 n reductions, somewhat less in magnitude but covering a larger area.

68 ings of bleaching within the Red Sea despite covering a latitudinal range of 15 degrees and consequen

69 and along a specific predefined raster path, covering a limited area.

70 o far, PSI-MS was only applied to procedures covering a limited number of targets.

71 ta document a multifunctional palace complex covering a maximum estimated area of 2,790 m(2) on the n

72 4.9 (standard deviation [SD], 2.8) networks covering a mean of 39.4% (SD, 26.2%) of those oncologist

73 Purpose Health insurers offer plans covering a narrow subset of providers in an attempt to l

74 of a spatially resolved data set on cod eggs covering a period (1959-1993) with large changes in biom

75 ial realm is a major part of the cryosphere, covering a quarter of Earth's land surface.

76 em tissue from human V1 (12 female, 18 male) covering a range of ages.

77 ra from a collection of metabolite standards covering a range of compound classes including amino aci

78 of porous monolithic materials was produced, covering a range of meso- and macroporous properties.

79 -Ci curves (564 species from 46 field sites, covering a range of plant functional types) to test the

80 te, as they are very rare and heterogeneous, covering a range of sizes and expressing different molec

81 between independent, overlapping SAR tracks covering a region 100 km in extent.

82 z and a maximum wall-plug efficiency of 6.5% covering a spectral coverage of 110 cm(-1) at lambda 8

83 several theoretical and experimental works, covering a subnanosecond time window with sample sizes o

84 ian culture spread over the Eurasian Steppe, covering a territory of more than 3,500 km in breadth.

85 ded 14 studies, 6 of which were prospective, covering a total of 4288419 men and women.

86 adoption of CAR, with registered properties covering a total of 57 Mha by 2013.

87 In this study, 11 fuel-stove combinations covering a variety of fuels and different stoves are inv

88 sample of male and female human participants covering a wide age range (6-85 years) across two differ

89 oblasts and keratinocytes cultured from skin covering a wide age range.

90 curate stereochemical information on samples covering a wide concentration range and drastically diff

91 including many previously unknown specimens, covering a wide geographic and temporal range.

92 ng 24 h exposures to 13 individual chemicals covering a wide range of contaminant classes.

93 etic whole exome and whole genome sequences, covering a wide range of diseases and syndromes.

94 Comprehensive functional gene arrays covering a wide range of ecological processes and stress

95 ensely sampled infectious disease outbreaks, covering a wide range of epidemiological settings.

96 tested using the experimental Rh of 22 IDPs covering a wide range of peptide lengths, net charge, an

97 etter sensitivity than conventional methods, covering a wide range of potential applications for meth

98 Thus, a series of 36 new derivatives covering a wide range of structural diversity has been s

99 ong-term gravimetric examination of kinetics covering about 4000 h was performed for phenol-water vap

100 generated a set of genomic microarray chips covering about 8000 bp flanking the predicted transcript

101 ntral nervous system (CNS) and its meningeal coverings accommodate a diverse myeloid compartment that

102 dation in both aqueous (over a wide pH range covering acidic, neutral, and alkaline) and alcohol medi

103 Using a comprehensive library of mutations covering all 352 residues of the GPCR CXC chemokine rece

104 and Zn) in 64 large marine ecosystems (LMEs) covering all coastal waters in the world.

105 While covering all commentaries, our response specifically foc

106 of the growing season across a large region covering all Europe for the year 2011.

107 ics with a laboratory surveillance database, covering all HPeV infections detected in Denmark during

108 One hundred and one IBS patients covering all IBS subtypes were recruited, and 39 non-IBS

109 a sources contained longitudinal information covering all individuals aged 15-94 years living in Denm

110 a collection of 81 Drosophila miRNA mutants covering almost the entire miRNA complement of the late

111 rement of individual and multiple parameters covering an animal's physiology as well as monitoring of

112 intact soil aggregate (40 measurements, each covering an area of 30 mum x 30 mum with a lateral resol

113 underwent 3861 screening MR imaging studies, covering an observation period of 7007 women-years.

114 The thick cuticle covering and embedding the epidermal cells of tomato (So

115 genomes to support the above five functions, covering animals, plants and bacteria and (iii) bacteria

116 d, high-frequency nitrate monitoring network covering approximately 40% of Iowa provided direct obser

117 s, identified a total of 2161 protein groups covering approximately 54% of the predicted M. tuberculo

118 the most important sources of natural fibre, covering approximately 80% of global bast fibre producti

119 es PubMed and Embase, combining search terms covering BD and ClockDelta19.

120 In this 7-year cross-sectional study (covering birth cohorts 1988-1995), we sampled approximat

121 inant tree species in 32,628 permanent plots covering boreal, temperate and Mediterranean forest biom

122 method was tested on seven seafood products covering both a wide concentration range and variations

123 they have never received a general treatment covering both cis and trans forms.

124 e to short-term change in MS, with questions covering both physical and psychological quality of life

125 A section covering caveats in the current work, and thus needed fu

126 identical sensor characteristics and assays covering clinically relevant concentrations in physiolog

127 e identify five conservation design elements covering critical ecological processes and patterns incl

128 addition reactions as 2pi or 4pi components (covering Diels-Alder and 1,3-dipolar cycloadditions).

129 of 8 Scotland-wide administrative databases covering dispensed prescriptions, admissions to acute an

130 lation study of diffusion in such materials, covering displacements from molecular dimensions up to t

131 port the analysis of 1776 cells by scRNA-seq covering distinct human embryonic stem cell-derived prog

132 tionship is also obtained at eddy-flux sites covering diverse biomes, setting the stage for future in

133 erated a site-saturation mutagenesis library covering each position along thiocillin's macrocyclic ri

134 analyzed through a developmental time series covering early seed lipid accumulation to seed maturity.

135 d-trimethylsilylated (MeOx-TMS) derivatives, covering elemental composition, typical substructures, n

136 with applications in a wide range of fields, covering engineering, physics, chemistry, biology and me

137 Twelve electronic databases covering English and Spanish language publications from

138 A decrease in the covering factor of the circumnuclear material with incre

139 ospital episode data in mid-2010 to mid-2015 covering five full calendar years were extracted from No

140 sses take place over a very broad timescale, covering five orders of magnitude.

141 ed biosensor exhibits a wide response range, covering four orders of magnitude, a limit of detection

142 uce coherent sub-harmonic optical waveforms, covering from terahertz (THz) to mid- and near-infrared

143 uid content of the small glandular trichomes covering fruits and leaves surfaces and also to be able

144 didate variants and genes for schizophrenia, covering genetic, epigenetic, transcriptomic, translatio

145 comprehensive overview of preclinical models covering genetically engineered organisms, models of tra

146 Using a global-scale dataset covering > 80% (7,904 species) of the living diversity o

147 atic variables and based on time-series data covering >40 y for six plankton and eight fish groups al

148 abundance data (1982-2015) in the Antarctic, covering >95% of their population globally.

149 PV genomes covering >99 to 100% of the reference length were obtain

150 ing 48 contigs (N50 contig length = 3.99 Mb) covering >99% of the 100,286,401-base reference genome.

151 erial artificial chromosome (BAC) reporters, covering hTERT and mTERT genes and their neighboring loc

152 activities have been successfully achieved, covering hydrosilylation, hydroboration, hydrovinylation

153 and field collections from over 30 countries covering its known geographic range.

154 d in the mushroom body, a neuronal structure covering large areas of the brain.

155 the deeper paint layers are absorbed in the covering layers.

156 CNV, named nsv823469 located on 6p22.1, and covering lncRNAs (major histocompatibility complex, clas

157 omising studies of a vast range of phenomena covering many disciplines from condensed matter to quant

158 ted research and para-research stories, also covering many wonderful people I had a privilege to work

159 sistent with the calculated reaction network covering metathesis, alkylidene loss, isomerization, and

160 ggesting the tiling model is better than the covering model for structural description.

161 rs, and connectivity of related networks, by covering more sensory and at least one putative motor co

162 to the hand encompasses a widespread network covering more than 10% of the cortical surface of both h

163 cs on imported malaria in the past 10 years, covering more than 50 000 individual cases.

164 atabase (NHIRD), a nationwide claim database covering more than 99% of the entire Taiwanese populatio

165 s to gastric cancer, and geographic origins, covering most continents.

166 measure THC in the range from 0 to 50 ng/mL, covering most cutoff values proposed in previous studies

167 vity with six a priori defined cortical ROIs covering most of the cortical mantle.

168 ns harboured long, fractionated electrograms covering most of the fibrillatory cycle lengths with var

169 depth resequencing of 63 different cultivars covering most of the genetic diversity in cultivated app

170 ncies conducted across 91 mammalian species, covering most of the size range in the orders Primates (

171 indolizine motif displaying tunable emission covering most of the visible spectrum.

172 one, depicts colder than normal temperatures covering most parts of the country while the second type

173 port the generation of a transcriptome atlas covering most phases in the life cycle of the model bryo

174 stic cell lines, which followed a trajectory covering multiple known cell state transitions, provided

175 ice production system using a large data set covering multiple locations with data collected from 199

176 models and a long-term data set ( 60 years) covering multiple trophic levels from phytoplankton to p

177 um is used to quantitatively investigate the covering nanomaterial based on subtle changes in the tra

178 and incorporate historical genetic diversity covering nearly the entire Atlantic coast of the America

179 By analyzing word lists covering nearly two-thirds of the world's languages, we

180 In this review, we start by covering new immunological insights originating from the

181 randomised controlled trials were included, covering non-selected and selected populations of both c

182 ols for high-dimensional omics data analysis covering normalization, pattern recognition, time-series

183 eneration of the epicardium, the mesothelial covering of the heart, is mediated by two phenotypically

184 y was used to show stomata on leptomeningeal coverings of blood vessels in the subarachnoid space as

185 100,000 residents and 3.2 (SD, 2.1) networks covering on average 49.9% (SD, 26.8%) of the area's onco

186 material but with or without a buffer layer covering one electrode, which confirm the origin of thes

187 Despite covering only 5% of the landscape, we estimate that aqu

188 Despite covering only approximately 138 000 km(2) , mangroves ar

189 below-tax alcohol sales, special duty rates covering only small shares of the market, and the impact

190 Despite covering only ~5% of the landscape, we estimate that aqu

191 d without pre-cleaning practices (prewiping, covering, or both) and soil load.

192 ial cells with lymphatic molecular signature covering parts of the brain without forming endothelial

193 iciency but also increase the probability of covering phased single-nucleotide polymorphisms (SNPs),

194 ardiomyopathy Questionnaire (KCCQ) (23 items covering physical function, social function, symptoms, s

195 r outcomes at lower costs from a perspective covering publicly funded healthcare services and product

196 recognition into the macromolecular domain, covering recent advances in anion recognition based on b

197 divided into sections according to modality, covering recent advances in the MR, PET, SPECT, ultrasou

198 focusing on experimental results, as well as covering recent results on the inhibition of liquid-liqu

199 ered but samples alpha-helical conformations covering residues 15-24 and 29-35 in the presence of mic

200 odels, assembled in a comprehensive workflow covering sequence quality control, automated sgRNA seque

201 independent PTSD blood transcriptome studies covering seven types of trauma in 229 PTSD and 311 compa

202 review provides the first in-depth overview covering several aspects related to the syntheses and ap

203 cortical LFP is measured by multielectrodes covering several cortical lamina and averaged on spontan

204 e III restriction enzyme to derive a densely covering sgRNA library from input DNA.

205 A set of 227 questions was created, covering six broad categories (days of the week, months

206 rther, participants completed questionnaires covering socio-demographic data and psychological functi

207 Covering spills decreased disinfection efficacy against

208 We developed an in vivo peptide library covering substrates of the ER Hsp70 system: BiP, Grp170,

209 re connected by sharing one edge rather than covering, suggesting the tiling model is better than the

210 Arborescent macro-algae forests covering temperate rocky reefs are a known habitat for j

211 am) for complete cyclic voltammetry profiles covering the 0.05-1.40 V range.

212 nal activity was confined to the time window covering the act of inhibition (300 ms-350 ms).

213 We engineered a weak-binding ligand covering the active site of the protease without address

214 peller with a flexible loop (residues 70-81) covering the active site.

215 Recently, a niche has started to be explored covering the analysis of middle-range peptides (i.e., 3.

216 E-ventus BX((R))) was implanted in the SMA, covering the aneurysmal neck and overlapping the previou

217 However, an overview covering the applications as well as the stereoselective

218 Covering the calendar years 2001 through to 2014, we obt

219 able to rapidly quantify WBC concentrations covering the common physiological and pathological range

220 gmentation to produce specific DNA molecules covering the complete microsatellite sequence.

221 detected in positive and negative ion modes covering the conducting and respiratory airways and part

222 ChIP-on-chip assay using anti-SOX9 antibody, covering the Ctgf gene from 15 kb upstream of its 5'-end

223 structed the first comparative transcriptome covering the daily embryonic developmental progression o

224 omprehensively review memory B cells (MBCs), covering the definition of MBCs and their identities and

225 100 mug mL(-1), with a LOD of 1.5 mug mL(-1) covering the diagnostic level of microalbuminuria of 30

226 Reviews covering the different facets of the RNAi antiviral immu

227 organic carbon are inferred from a box-model covering the eastern boundary of the North Atlantic subt

228 ibraries of oocytes and successive intervals covering the embryonic development of the short germband

229 Suberin lamellae are glycerolipid polymers covering the endodermal cells and likely function as a b

230 The hypothesis of a km-thick ice shelf covering the entire Arctic Ocean during peak glacial con

231 k of zoster using electronic healthcare data covering the entire Danish population and general practi

232 sm for generating complementary neural codes covering the entire dynamic range.

233 ots gradually shifts from blue to red light, covering the entire light spectrum.

234 ner with the aid of quantum chemistry tools, covering the entire pH range from 0-14.

235 An unbiased alanine-scanning screen covering the entire region combined with quantitative el

236 later developmental stages, necrosis spread, covering the entire stem and extending into the leaves o

237 ere quantified via summation over all slices covering the entire ventricle.

238 (TMGS) can achieve high-contrast BAT spectra covering the entire visible region.

239 vivo electrograms were acquired at 240 sites covering the epicardium of 41 patients at 6 cycle length

240 The response was lost upon covering the eyes, demonstrating that the signal is perc

241 d sedimentary sequence from Neapolis' harbor covering the first six centuries CE have recorded how th

242 the formation of a large protein-RNA complex covering the free ends of the two rps12 intron halves.

243 p 3 protein was also localized in trichomes covering the fruit epidermis.

244 The epicardial sheet covering the heart is activated by injury and aids muscl

245 structs and by epitope mapping with peptides covering the identified region of ANO2.

246 The lipid-protein film covering the interface of the lung alveolar in mammals i

247 x-ray crystal structure of an HAI-1 fragment covering the internal domain and Kunitz-1.

248 pe (rs10420331-rs11084307, P = 1.4 x 10(-6)) covering the intronic region of CACNG8 to be significant

249 ch as DRME model based on a statistical test covering the IP samples only with 2 negative binomial di

250 Rhea describes enzyme-catalyzed reactions covering the IUBMB Enzyme Nomenclature list as well as a

251 rmed regular two-dimensional trigonal arrays covering the large facets of disc-shaped TPP nanocrystal

252 When the muscles covering the lch5 organ were excised, the slow relaxatio

253 ope, and applications of the RuAAC reaction, covering the literature from the last 10 years.

254 and related compounds in organic synthesis, covering the literature from the last 12 years.

255 a particular focus on asymmetric catalysis, covering the literature of the last decade until July 20

256 assembly of structurally diverse scaffolds, covering the literature over the past 12 years (from 200

257 This review of assembly-line phenomena, covering the literature up to 2017, should thus be infor

258 th mass spectrometric detection (IC-ICP-MS), covering the main rice-growing regions of the Iberian Pe

259 RNA transcriptomes for six cell populations covering the major cell types of the Arabidopsis root me

260 their complementary neutralization patterns covering the majority of epidemiologically relevant HIV-

261 lower-middle income, and upper-middle income covering the majority of these adolescents globally to d

262 e detector response ranged from 0 to 60 ppm, covering the normal range of nitrate in soil.

263 t the treeline across a latitudinal gradient covering the northern, central and southernmost populati

264 nalysis of fluorophore-labeled PCR amplicons covering the nuclease target site by capillary electroph

265 conditions from central-eastern Baffin Bay, covering the period 14.0-10.2 kyr BP.

266 12 studies were included covering the period 1949-2012 (27 423 patients; 6628 dea

267 ular vertical lower-troposphere CH4 profiles covering the period 2010-2013.

268 and interpolated-IS daily rainfall datasets covering the period of 1998-2013.

269 Axis Disorders at 6- and 12-month follow-up, covering the period to the previous assessment.

270 nal surfaces within the renal vasculature by covering the point of contact between donor vascular end

271 hrough WHO country offices, with each survey covering the previous 12-mo period.

272 waste dumps, and analytical-grade material, covering the production time period from the late 1960s

273 als developed for ASC electrodes, as well as covering the progress made in the fabrication of ASC dev

274 talline fraction in the magnetic field range covering the proton Larmor frequencies from 0.01 to 25MH

275 average superfluid rigidity on length scales covering the range from microscopic to macroscopic.

276 n 0-52.5 mL/h at 32-39 degrees C, adequately covering the range of interest.

277 suitable for over three orders of magnitude, covering the range of v-c concentrations in faba bean se

278 ials exists, there is an absence of guidance covering the required content of statistical analysis pl

279 Retrospective studies suggested a benefit of covering the resection margin by a teres ligament patch.

280 This article is part 1 of a 3-part series covering the role of oxidative stress in cardiovascular

281 1233 single nucleotide polymorphisms (SNPs) covering the significant linkage region in 162 French Ep

282 ations from Transoxiana, a historical region covering the southwestern part of Central Asia.

283 nformational properties of the glycan shield covering the surface of the HIV gp120/gp41 envelope (Env

284 nocrystal facets can be tuned by selectively covering the surface with ligands of tunable thickness.

285 m the Belukha glacier in the Siberian Altai, covering the time period 1680-2001.

286 from a comparative study of ten hot Jupiters covering the wavelength range 0.3-5 micrometres, which a

287 s of spectra from ground-based observatories covering the wavelength range from the ultraviolet to th

288 Data from ILO were from 146 countries covering the years between 2000 and 2012.

289 es carbon to photosynthesize and to calcify, covering their cells with chalk platelets (coccoliths).

290 aptively imparted to metallic nanoparticles, covering them to generate structures with plasmonic chir

291 and store revenue for two supermarket chains covering three Berkeley and six control non-Berkeley lar

292 e force over a broad range of loading rates, covering three orders of magnitude.

293 reased in blood cells of irradiated animals, covering three types of genotoxic activity.

294 light on a rich and diverse range of motions covering timescales from picoseconds to seconds.

295 Transcription analysis covering up to 26 genes showed that mostly genes related

296 We list the most prominent data sets covering various aspects of the field, from general ones

297 genes based on 144 RNA sequencing data sets covering various stages of macronutrient deficiencies an

298 oupled with GCxGC-TOF-MS is the first report covering volatiles to low-volatile organic mixtures.

299 M), plastic film mulch (PM) and conventional covering without mulch (CK).

300 l child and adolescent mental health policy, covering young people until their official age of transi