ライフサイエンスコーパス: coxsackievirus

1 ood mononuclear immune cells that respond to Coxsackievirus.

2 for some adenovirus (AdV) types and group B coxsackieviruses.

3 -fold more resistant to in vitro cleavage by Coxsackievirus 2A protease (2A(Pro)) than wild-type eIF4

4 man K562 cells were cleaved with recombinant Coxsackievirus 2A protease and the N- terminal domains p

5 nt for viral myocarditis is the B3 strain of coxsackievirus, a positive-sense RNA enterovirus.

6 Human enterovirus 71 (EV71) and coxsackievirus A16 (CA16) are the major etiological agen

7 ssay, neutralizing antibodies titers against coxsackievirus A16 (CA16), enterovirus 71 (EV71), PV I-I

8 e two serotypes Enterovirus A71 (EV-A71) and Coxsackievirus A16 (CV-A16) being responsible for the ma

9 Coxsackievirus A16 (CV-A16), CV-A6, and enterovirus D68

10 Enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) are the primary causes of the

11 causative agents are enterovirus 71 (EV71), coxsackievirus A16 (CVA16), and, most recently, coxsacki

12 interspersed phylogenetically with clades of coxsackievirus A16 and other EV species A serotypes.

13 s most typically caused by enterovirus 71 or coxsackievirus A16 and results in asymptomatic infection

14 Unlike coxsackievirus A16, which also causes HFMD, EV71 induces

15 poliovirus 2C(ATPase) interacts with VP3 of coxsackievirus A20, in the context of a chimeric virus.

16 Coxsackievirus A21 (CAV21) is classified within the spec

17 Coxsackievirus A21 (CAV21), like human rhinoviruses (HRV

18 In vivo mouse RT-adapted, variant coxsackievirus A21 exhibited replication competence in t

19 ution of variants of the common-cold-causing coxsackievirus A21, an EV with tropism for the human int

20 Coxsackievirus A24 (CV-A24) was not originally associate

21 Incubation of coxsackievirus A24 and enterovirus 70 with 2.5 mM NVC-42

22 everal serotypes of human adenovirus (HAdV), coxsackievirus A24, enterovirus 70, and herpes simplex-v

23 ent targets for designing anti-CVA6 vaccines.Coxsackievirus A6 (CVA6) causes hand, foot and mouth dis

24 Coxsackievirus A6 (CVA6) DNA was identified in the blist

25 Coxsackievirus A6 (CVA6) has recently emerged as a major

26 sackievirus A16 (CVA16), and, most recently, coxsackievirus A6 (CVA6).

27 His infection with coxsackievirus A6 was confirmed based on polymerase chai

28 ar with the severe variant of HFMD caused by coxsackievirus A6, include it in their differential diag

29 se severe cases were most commonly caused by coxsackievirus A6.

30 Coxsackievirus A9 (CAV9), a member of the Picornaviridae

31 ntains the echoviruses, coxsackie B viruses, coxsackievirus A9, and enterovirus 69.

32 ral loads were in meningitis cases caused by coxsackievirus A9, B4, and B5 genotypes.

33 -B) in the family Picornaviridae consists of coxsackievirus A9; coxsackieviruses B1 to B6; echoviruse

34 ith different fiber shaft lengths and either coxsackievirus-Ad receptor (CAR)-interacting Ad serotype

35 expression of the major attachment receptor, coxsackievirus-Ad receptor (CAR).

36 The knobs remained trimeric and bound the coxsackievirus-Ad receptor, and the phage knob-displayed

37 t HD-RIGIE injections efficiently transduced coxsackievirus adenovirus receptor-expressing keratocyte

38 This Ad5/35 vector infects cells via a coxsackievirus adenovirus receptor-independent pathway.

39 racting with soluble extracellular domain of coxsackievirus adenovirus receptors (s-CAR).

40 Adenoviruses that infect through the coxsackievirus-adenovirus receptor (CAR) (Ad2 and Ad5) a

41 The coxsackievirus-adenovirus receptor (CAR) and decay-accel

42 While the majority of serotypes utilize coxsackievirus-adenovirus receptor (CAR) as their primar

43 d5) involves fiber capsid protein binding to coxsackievirus-adenovirus receptor (CAR) at the cell sur

44 majority of adenovirus serotypes utilize the coxsackievirus-adenovirus receptor (CAR) for virus-host

45 ropism of the virus for the widely expressed coxsackievirus-adenovirus receptor (CAR) protein.

46 We hypothesized that the expression of the coxsackievirus-adenovirus receptor (CAR), a viral recept

47 Both the coxsackievirus-adenovirus receptor (CAR), an Ig-like mol

48 e variant of the extracellular domain of the coxsackievirus-adenovirus receptor (sCAR-Fc) was express

49 rabasal cells that express the high-affinity coxsackievirus-adenovirus receptor, CAR, whereas the pro

50 y infect B-cell lines due to the lack of the coxsackievirus-adenovirus receptor.

51 Ad) fiber protein mediates Ad binding to the coxsackievirus and Ad receptor (CAR) and is thus a major

52 f the primary cellular receptor for Ads, the coxsackievirus and Ad receptor (CAR), in permitting intr

53 have shown that although Ad2ts1 can bind the coxsackievirus and Ad receptor and undergo internalizati

54 hafted Ad vectors had no impact on knob-CAR (coxsackievirus and Ad receptor) interaction compared to

55 ished Ad receptors, namely, integrins or the coxsackievirus and Ad receptor.

56 onal adhesion molecule 1 (JAM1), but not the coxsackievirus and Ad receptor.

57 s 259 and 260 in the cytoplasmic tail of the coxsackievirus and adenovirus receptor (CAR) are known t

58 While group B coxsackieviruses (CVB) use the coxsackievirus and adenovirus receptor (CAR) as the rece

59 ruses into target cells is expression of the coxsackievirus and adenovirus receptor (CAR) at the cell

60 The coxsackievirus and adenovirus receptor (CAR) has been id

61 associated with the widespread expression of coxsackievirus and adenovirus receptor (CAR) in normal h

62 The coxsackievirus and adenovirus receptor (CAR) is a compon

63 The coxsackievirus and adenovirus receptor (CAR) is a compon

64 The coxsackievirus and adenovirus receptor (CAR) is a member

65 The coxsackievirus and adenovirus receptor (CAR) is a primar

66 The coxsackievirus and adenovirus receptor (CAR) is a transm

67 The coxsackievirus and adenovirus receptor (CAR) is both a v

68 we demonstrate that in the adult brain, the coxsackievirus and adenovirus receptor (CAR) is located

69 The coxsackievirus and adenovirus receptor (CAR) mediates at

70 The coxsackievirus and adenovirus receptor (CAR) mediates en

71 The coxsackievirus and adenovirus receptor (CAR) mediates vi

72 rity of adenovirus serotypes can bind to the coxsackievirus and adenovirus receptor (CAR) on human ce

73 protein serves this purpose, binding to the coxsackievirus and adenovirus receptor (CAR) present on

74 Vesicles shed by U87-MG cells contain coxsackievirus and adenovirus receptor (CAR) protein tha

75 In this study, a zebrafish homologue of the coxsackievirus and adenovirus receptor (CAR) protein was

76 The human coxsackievirus and adenovirus receptor (CAR) represents

77 The coxsackievirus and adenovirus receptor (CAR) serves as a

78 novirus serotype 5 fiber protein engages the coxsackievirus and adenovirus receptor (CAR) to bind cel

79 This study addressed the role of the coxsackievirus and adenovirus receptor (CAR), a single-p

80 s many adenoviruses infect cells through the coxsackievirus and adenovirus receptor (CAR), group B ad

81 The coxsackievirus and adenovirus receptor (CAR), which medi

82 PEGylation completely abrogated coxsackievirus and adenovirus receptor (CAR)-knob intera

83 cytokine responses than Ad5, which uses the coxsackievirus and adenovirus receptor (CAR).

84 -accelerating factor (DAF) as well as to the coxsackievirus and adenovirus receptor (CAR).

85 low virus interaction with DAF, and with the coxsackievirus and adenovirus receptor (CAR).

86 s can initiate infection by attaching to the coxsackievirus and adenovirus receptor (CAR).

87 -accelerating factor (DAF) as well as to the coxsackievirus and adenovirus receptor (CAR).

88 The LG abundantly expresses the coxsackievirus and adenovirus receptor (CAR); furthermor

89 V3 cells transfected to stably express human coxsackievirus and adenovirus receptor [CAR]).

90 and reveal a direct interaction between the coxsackievirus and adenovirus receptor and the immune sy

91 The coxsackievirus and adenovirus receptor protein (CAR) ser

92 presence of varied concentrations of soluble coxsackievirus and adenovirus receptor showed that the o

93 es), cardiac fibrosis, apoptosis, lower CAR (Coxsackievirus and adenovirus receptor) expression and C

94 tudy demonstrates that hiPSC-CMs express the coxsackievirus and adenovirus receptor, are susceptible

95 inity of Ad5 fiber for the cellular receptor coxsackievirus and adenovirus receptor, CAR.

96 lls and transduction of cells expressing the coxsackievirus and adenovirus receptor.

97 beta, tumor-derived growth factor beta; CAR, coxsackievirus and adenovirus receptor; MLV, murine leuk

98 ase-control study of the association between coxsackieviruses and cardiac impairment, 24 human immuno

99 is the primary cellular receptor for group B coxsackieviruses and most adenovirus serotypes and plays

100 ves as the cell surface receptor for group B coxsackieviruses and most adenoviruses, but the physiolo

101 molytic streptococci and rheumatic fever; B3 Coxsackieviruses and myocarditis; Trypanosoma cruzi and

102 FP(A20) exhibited up to 50-fold increases in coxsackievirus- and-adenovirus-receptor-independent tran

103 binds with high affinity to the cell surface coxsackievirus-and-adenovirus receptor (CAR), and penton

104 egression to test for an association between coxsackievirus antibody titer and the presence or absenc

105 Coxsackievirus antibody titers correlated positively wit

106 = .12), human bocavirus (aOR 9.1, P < .01), Coxsackieviruses (aOR 5.1, P = .09), rhinovirus A (aOR 3

107 Group B coxsackieviruses are associated with chronic inflammator

108 ous observations suggesting that the group B coxsackieviruses are associated with the risk of type 1

109 Group B coxsackieviruses are responsible for chronic cardiac inf

110 Coxsackieviruses are significant human pathogens causing

111 Coxsackieviruses are significant human pathogens, and th

112 ntacts within the canyon are responsible for coxsackievirus attachment.

113 Previous studies have suggested that coxsackievirus B (CVB) activates CD8(+) T cells in vivo,

114 adenovirus receptor (CAR) mediates entry of coxsackievirus B (CVB) and adenovirus (Ad).

115 al dissemination in released EMVs.IMPORTANCE Coxsackievirus B (CVB) can cause a number of life-threat

116 Coxsackievirus B (CVB) is a common cause of acute and ch

117 Coxsackievirus B (CVB) is a common enterovirus that can

118 Many coxsackievirus B (CVB) isolates bind to human decay-acce

119 alized host factor that negatively regulates coxsackievirus B (CVB) replication through its control o

120 ental murine infections and in cell culture, coxsackievirus B (CVB) RNA can persist for weeks in the

121 eptors for poliovirus, human rhinovirus, and coxsackievirus B (CVB) serve to bind the viruses to targ

122 Coxsackievirus B (CVB), a member of the enterovirus fami

123 enteroviruses, including echovirus 11 (E11), coxsackievirus B (CVB), and enterovirus 71 (EV71), and t

124 These viruses, which include coxsackievirus B (CVB), poliovirus (PV), and enterovirus

125 sponses to candidate viral pathogens such as coxsackievirus B (CVB).

126 Coxsackievirus B infections are suspected environmental

127 Many coxsackievirus B isolates bind to human decay-accelerati

128 pDC activation by Coxsackievirus B requires the presence of specific antiv

129 The shared cellular receptor, the Coxsackievirus B-Adenovirus receptor (CAR), for the two

130 cognizes the genome of ssRNA viruses such as Coxsackievirus B.

131 Mice infected with myopathic coxsackievirus B1 Tucson (CVB1(T)) develop chronic infla

132 Coxsackievirus B1 was associated with an increased risk

133 sting immunological cross-protection against coxsackievirus B1.

134 icornaviridae consists of coxsackievirus A9; coxsackieviruses B1 to B6; echoviruses 1 to 7, 9, 11 to

135 uvirus, human rhinovirus 14, poliovirus, and coxsackievirus B2, B3, and B5.

136 fection with a suspected diabetogenic virus, Coxsackievirus B3 (CB3), NOD.Ncf1(m1J) mice remained res

137 of IL-12 and IFN-gamma on the development of Coxsackievirus B3 (CB3)-induced myocarditis, we examined

138 The first-described DAF-binding isolate, coxsackievirus B3 (CB3)-RD, was obtained during passage

139 region of a full-length infectious clone of coxsackievirus B3 (CBV3).

140 ngth VP1 genes of poliovirus 1 (Polio 1) and coxsackievirus B3 (Cox B3) were cloned, and the encoded

141 Coxsackievirus B3 (CV-B3) is a cardiovirulent enteroviru

142 d identified RIP3 as a positive regulator of coxsackievirus B3 (CVB) replication in intestinal epithe

143 ne was effective against poliovirus (PV) and coxsackievirus B3 (CVB3) and exhibited greater activity

144 Here, we orally infected mice with coxsackievirus B3 (CVB3) and found that CVB3 replication

145 With Coxsackievirus B3 (CVB3) being a single-stranded RNA vir

146 The myocarditic (H3) variant of Coxsackievirus B3 (CVB3) causes severe myocarditis in BA

147 B infection, we previously demonstrated that coxsackievirus B3 (CVB3) could infect neuronal progenito

148 larized human intestinal epithelial cells by coxsackievirus B3 (CVB3) depends on virus interaction wi

149 ar to humans, male BALB/c mice infected with coxsackievirus B3 (CVB3) develop more severe inflammatio

150 Male BALB/c mice infected with coxsackievirus B3 (CVB3) develop more severe inflammator

151 Here we show that coxsackievirus B3 (CVB3) exhibits reduced mutational rob

152 we describe the generation of a recombinant coxsackievirus B3 (CVB3) expressing the enhanced green f

153 Coxsackievirus B3 (CVB3) generates 5'-terminally deleted

154 Passage of coxsackievirus B3 (CVB3) in adult murine cardiomyocytes

155 eviously described a neonatal mouse model of coxsackievirus B3 (CVB3) infection and determined that p

156 Coxsackievirus B3 (CVB3) infection induces death of card

157 Acute coxsackievirus B3 (CVB3) infection is one of the most co

158 Acute coxsackievirus B3 (CVB3) infection is one of the most pr

159 ate immunity can determine susceptibility to coxsackievirus B3 (CVB3) infection, the present study ev

160 Coxsackievirus B3 (CVB3) is a causative agent of viral m

161 Coxsackievirus B3 (CVB3) is a common human pathogen that

162 Coxsackievirus B3 (CVB3) is a major cause of acute myoca

163 Coxsackievirus B3 (CVB3) is a major heart pathogen again

164 Coxsackievirus B3 (CVB3) is a picornavirus which causes

165 Coxsackievirus B3 (CVB3) is a principal viral cause of a

166 The initiation codon of coxsackievirus B3 (CVB3) is flanked by both R-3 and G+4

167 Coxsackievirus B3 (CVB3) is known to infect stem cells i

168 esent recent findings on the pathogenesis of coxsackievirus B3 (CVB3) myocarditis based on animal mod

169 f a 3C protease inhibitor (3CPI) in a murine coxsackievirus B3 (CVB3) myocarditis model.

170 l mouse model, we previously determined that coxsackievirus B3 (CVB3) preferentially targets prolifer

171 We have previously shown that three coxsackievirus B3 (CVB3) proteins (2B, 2BC, and 3A) targ

172 ed in pancreatic acinar cells, and show that coxsackievirus B3 (CVB3) requires autophagy for optimal

173 Previously, we described the ability of coxsackievirus B3 (CVB3) to infect proliferating neurona

174 We used the enterovirus coxsackievirus B3 (CVB3) to investigate the effects of h

175 We previously demonstrated the ability of coxsackievirus B3 (CVB3) to persist within the neonatal

176 Here we investigate coxsackievirus B3 (CVB3) tropism and pathology in the CN

177 xchanges between poliovirus type 1 (PV1) and coxsackievirus B3 (CVB3) utilizing an in vitro translati

178 Two coxsackievirus B3 (CVB3) variants (H3 and H310A1) differ

179 Two coxsackievirus B3 (CVB3) variants infect and replicate i

180 By replacing the entire 5' NTR of coxsackievirus B3 (CVB3) with that from type 1 polioviru

181 Coxsackievirus B3 (CVB3), an important human causative p

182 The IRESs of poliovirus, the cardiotropic coxsackievirus B3 (CVB3), and the hepatotropic hepatitis

183 mice, IL-13 KO BALB/c mice developed severe coxsackievirus B3 (CVB3)-induced autoimmune myocarditis

184 In this study, we examined the role of CR on coxsackievirus B3 (CVB3)-induced myocarditis using mice

185 e of protease-activated receptor-2 (PAR2) in coxsackievirus B3 (CVB3)-induced myocarditis.

186 We aimed to investigate their role in Coxsackievirus B3 (CVB3)-induced myocarditis.

187 und that signaling via IL-12Rbeta1 increases coxsackievirus B3 (CVB3)-induced myocarditis.

188 sL) interactions regulate disease outcome in coxsackievirus B3 (CVB3)-induced myocarditis.

189 T-cell receptor (TCR) promote myocarditis in coxsackievirus B3 (CVB3)-infected BALB/c mice.

190 ve been identified as cellular receptors for coxsackievirus B3 (CVB3).

191 es that evaluate the effects on autophagy of coxsackievirus B3 (CVB3).

192 ve been identified as cellular receptors for coxsackievirus B3 (CVB3).

193 , CAR4/7 but not CAR2/7 was found to bind to coxsackievirus B3 (CVB3).

194 ed enteroviruses poliovirus type 1 (PV1) and coxsackievirus B3 (CVB3).

195 yopathy include cardiotropic viruses such as coxsackievirus B3 (CVB3).

196 Giving C57BL/6 mice 10(4) PFU of coxsackievirus B3 (H3 variant) fails to induce myocardit

197 oliovirus, foot-and-mouth disease virus, and coxsackievirus B3 and can lead to reduced cell surface e

198 f the genomic deletions observed in vivo for coxsackievirus B3 biology.

199 Enteroviruses such as Coxsackievirus B3 can cause dilated cardiomyopathy throu

200 l targeting of key residues, and screens for Coxsackievirus B3 fidelity variants, we isolated nine po

201 rditis in some patients, and the role of the coxsackievirus B3 has been debated.

202 iants corresponding to Poliovirus type 1 and Coxsackievirus B3 have virtually the same structure, bas

203 N receptors has little or no effect on acute coxsackievirus B3 infection in the heart.

204 Furthermore, Coxsackievirus B3 infection of cell lines expressing mut

205 t expression of full-length dystrophin after coxsackievirus B3 infection.

206 the sarcoglycans from the sarcolemma during coxsackievirus B3 infection.

207 induced after intraperitoneal inoculation of coxsackievirus B3 into C57Bl/6 IRAK4-deficient mice and

208 Coxsackievirus B3 mRNA and hepatitis C virus mRNA were f

209 inistration on the development of autoimmune coxsackievirus B3 myocarditis and dilated cardiomyopathy

210 The crystal structure of the coxsackievirus B3 polymerase has been solved at 2.25-A r

211 have previously engineered more than a dozen coxsackievirus B3 polymerase mutations that significantl

212 d to characterize 15 engineered mutations in coxsackievirus B3 polymerase.

213 s were infected with a luciferase-expressing coxsackievirus B3 strain (CVB3-Luc).

214 Recently, coxsackievirus B3 strains with 5'-terminal deletions in

215 esults from receptor-catalyzed conversion of coxsackievirus B3 to non-infectious A-particles.

216 BL/6 endothelial cells with a nonmyocarditic coxsackievirus B3 variant, H310A1, which is a poor induc

217 ated that infection by another picornavirus (coxsackievirus B3) causes SRp20 to relocalize from the n

218 bitors that block replication of poliovirus, coxsackievirus B3, and encephalomyocarditis virus.

219 f Aichi virus, bovine kobuvirus, poliovirus, coxsackievirus B3, and human rhinovirus 14 all copurify

220 on is enhanced in cells infected with the EV coxsackievirus B3, but the related poliovirus has no sig

221 om the binding site of DAF on the surface of coxsackievirus B3, indicating that there are independent

222 this study, we analyzed the role of PAR-1 in coxsackievirus B3-induced (CVB3-induced) myocarditis and

223 re profiled in both human myocarditis and in Coxsackievirus B3-injected mice, comparing myocarditis-s

224 pes, including survival after infection with coxsackievirus B3.

225 he cloverleaf RNA structure of the 5'-UTR of coxsackievirus B3.

226 nst hepatitis C virus, human rhinovirus, and coxsackievirus B3.

227 nsfected cells by both adenovirus type 5 and coxsackievirus B3.

228 conjugated to enteroviruses echovirus 1 and coxsackievirus B3.

229 A59, Theiler's encephalomyelitis virus, and Coxsackievirus B3] in mice with autoantibodies to a cent

230 Two other coxsackieviruses, B3 and B6, were associated with a redu

231 In mice, coxsackievirus B4 (CB4) induces insulin-dependent diabet

232 Coxsackievirus B4 (CBV4), a member of the Picornavirus g

233 acteristics of the T-cell response to the EV Coxsackievirus B4 (CVB4) in patients with type 1 diabete

234 tion in nonobese diabetic (NOD) mice through coxsackievirus B4 (CVB4) infection requires a preexistin

235 This study of the pancreatropic enterovirus Coxsackievirus B4 (CVB4) shows that although infection a

236 nse plays a critical role in protection from coxsackievirus B4 (CVB4)-induced diabetes.

237 ells to interferons (IFNs) and prevention of coxsackievirus B4 (CVB4)-induced diabetes.

238 uman fetal thymus organ cultures (FTOC) with coxsackievirus B4 E2 (CVB4 E2) was investigated.

239 pancreatitis by using a virulent variant of coxsackievirus B4, CVB4-V.

240 ve analysis of global gene expression during coxsackievirus B4-induced acute and chronic pancreatitis

241 -cell biology, we investigated the impact of coxsackievirus B5 (CVB5) infection on the cellular expre

242 beacons (MBs) for the real-time detection of coxsackievirus B6 replication in living Buffalo green mo

243 uced into BGMK cell monolayers infected with coxsackievirus B6, a discernible fluorescence was observ

244 Group B coxsackieviruses can initiate rapid onset type 1 diabete

245 CAR residues interacting deep within the coxsackievirus canyon are highly conserved in zCAR and h

246 Newborn pups were extremely vulnerable to coxsackievirus CNS infection, and this susceptibility de

247 ovirus (E) 6 (7.6%), E14 (7.6%), E11 (7.4%), coxsackievirus (CV) B3 (7.4%), E25 (5.6%), CVB5 (4.9%),

248 e consequence of myocarditis associated with Coxsackievirus (CV) infection.

249 Coxsackievirus (CV) is an important human pathogen that

250 The group B coxsackieviruses (CVB) are commonly named as putative T1

251 Maternal-fetal transmission of group B coxsackieviruses (CVB) during pregnancy has been associa

252 Type B coxsackieviruses (CVB) frequently infect the CNS and, to

253 Viral infections by coxsackieviruses (CVB) may contribute to trigger autoimm

254 While group B coxsackieviruses (CVB) use the coxsackievirus and adenov

255 Group B coxsackieviruses (CVB) use the CVB and adenovirus recept

256 Group B coxsackieviruses (CVBs) must cross the epithelium as the

257 type-specific antibodies against the group B coxsackieviruses (CVBs), which have been linked to diabe

258 rrelia burgdorfii and Lyme arthritis; and B4 Coxsackievirus, cytomegalovirus or rubella and type 1 di

259 Despite replicating to very high titers, coxsackieviruses do not elicit strong CD8 T-cell respons

260 Infections with the group B coxsackieviruses either can be asymptomatic or can lead

261 Both poliovirus and coxsackievirus encode a small polypeptide, VPg, which se

262 Enteroviruses, including coxsackieviruses, exhibit significant tropism for the ce

263 se results do not identify a causal role for coxsackieviruses for cardiomyopathy in HIV-1-infected ch

264 Coxsackievirus group B (CVB) adhered to the surface of C

265 PAR2 negatively regulates expression during coxsackievirus group B infection.

266 Structures of 3D(pol) from poliovirus, coxsackievirus, human rhinoviruses, and other picornavir

267 e replication of poliovirus, rhinovirus, and coxsackievirus in cell culture.

268 ntified as the cellular receptor for group B coxsackieviruses, including serotype 3 (CVB3).

269 espect, IKK-induced cardiomyopathy resembled Coxsackievirus-induced myocarditis, during which the NF-

270 be used to model the pathogenic processes of coxsackievirus-induced viral myocarditis and to screen a

271 eplication, cardiomyopathy, and mortality in coxsackievirus-infected mice.

272 0; P=.75), indicating no association between coxsackievirus infection and cardiac impairment.

273 extreme susceptibility of newborn infants to coxsackievirus infection and viral tropism for the CNS,

274 Serologic evidence of coxsackievirus infection was present in all children, wi

275 and adenovirus receptor, are susceptible to coxsackievirus infection, and can be used to predict ant

276 hanisms of innate immune responses following coxsackievirus infection.

277 peroxynitrite in the host immune response to Coxsackievirus infection.

278 5 patients showed no evidence of intervening coxsackievirus infection.

279 hermore, a sex bias for severe sequelae from coxsackievirus infections has been observed in humans.

280 Neonates are particularly susceptible to coxsackievirus infections of the central nervous system

281 Coxsackievirus is an enteric virus that initiates infect

282 s as an antiviral factor during infection by coxsackievirus or human rhinovirus, suggesting a common

283 he RNA template sequence, the origin of VPg (coxsackievirus or poliovirus), the origin of 3D polymera

284 or poliovirus), the origin of 3D polymerase (coxsackievirus or poliovirus), the presence and origin o

285 In a previous study, we found that coxsackievirus polymerase activity increased or decrease

286 Here we use coxsackievirus polymerase to show that elongation activi

287 dystrophin is proteolytically cleaved by the Coxsackievirus protease 2A leading to functional impairm

288 sults contribute to our understanding of the coxsackievirus-receptor interactions.

289 Enteroviruses such as poliovirus and coxsackievirus recruit PI4KIIIbeta to their replication

290 Thus, coxsackieviruses rely on the combined effects of several

291 merase; we suggest that this may represent a coxsackievirus replication complex.

292 viral replication, we sought to investigate coxsackievirus replication within the intestine.

293 ally important pathogens such as poliovirus, coxsackievirus, rhinovirus, enterovirus 71 and foot-and-

294 ypes of cardiomyocytes, we demonstrated that coxsackievirus RNAs harboring 5' deletions ranging from

295 Of interest, only T1D-associated Coxsackievirus serotype B4 but not B3 induced majority o

296 experiments use intraperitoneal injection of coxsackievirus to infect mice, bypassing the intestine.

297 pro) proteins from diverse enteroviruses and coxsackieviruses to interfere with type I IFN induction

298 ribe an "Open sesame!" strategy developed by coxsackieviruses to invade the organism through the inte

299 Chemicon) with 10 poliovirus, echovirus, and coxsackievirus type A and B stock isolates and College o

300 encapsidation of poliovirus and of C-cluster coxsackieviruses, which are prototypes of enteroviruses,