ライフサイエンスコーパス: cranial suture

1 opically reminiscent of the adjacent natural cranial suture.

2 of FGFR2c to multiple FGFs expressed in the cranial suture.

3 nd results from the premature fusion of >/=1 cranial sutures.

4 the fibrous joints between the bones, termed cranial sutures.

5 These mice exhibit cranial suture and sternal fusions that are exacerbated

6 ts in a more severe delay in ossification of cranial sutures and fontanels than occurs with Runx2 hap

7 We also observed premature fusion of the cranial sutures and low bone density in newborn FGFR3(G3

8 nalling dynamics, whereby development of the cranial sutures and sternum follows a morphogen mode, wh

9 zed by craniosynostosis (premature fusion of cranial sutures) and severe syndactyly of the hands and

10 h as the mandibular condyle, calvarial bone, cranial suture, and subcutaneous adipose tissue--have be

11 splasia characterized by short stature, wide cranial sutures, and increased bone density and fragilit

12 suture mesenchyme of patent, but not fusing, cranial sutures, and that noggin expression is suppresse

13 craniofacial geometry, irregular patterns of cranial suturing, and ectopic bone formation.

14 at differences in the morphology of selected cranial sutures between species that span the fish-tetra

15 new insights, both into normal and abnormal cranial suture biogenesis and into problems of broad int

16 arpenter syndrome implicates HH signaling in cranial-suture biogenesis--an unexpected finding, given

17 synostosis based on current understanding of cranial suture biology and molecular and developmental p

18 animal models and improved uncerstanding of cranial suture biology and pathology may lead to complem

19 This work addressed a hypothesis that a cranial suture can be tissue-engineered from autologous

20 Premature fusion of cranial sutures, caused by deficiency in intramembranous

21 to growth plate abnormalities and premature cranial suture closure because of precocious maturation

22 ithelium during palatal fusion and postnatal cranial suture closure during skull development.

23 ovel molecule overexpressed during premature cranial suture closure in patients with craniosynostosis

24 h a series of tissue interactions within the cranial suture complex.

25 hat the Mgp promoter is highly active at the cranial sutures, cranial base synchondroses, and nasal s

26 idermal hyperplasia and premature closure of cranial sutures (craniosynostosis) due to abnormal cell

27 Premature fusion of one or more of the cranial sutures (craniosynostosis) in humans causes over

28 Premature fusion of the cranial sutures (craniosynostosis), affecting 1 in 2000

29 Cranial suture development involves a complex interactio

30 reviously unsuspected role for Zic1 in early cranial suture development, potentially by regulating en

31 ipally the mouse, because of similarities in cranial suture development.

32 tional modules active at different stages of cranial suture development.

33 ach may be refined for tissue engineering of cranial sutures for craniosynostosis patients.

34 congenital malformation in which one or more cranial sutures fuse prematurely.

35 enetically determined disorders of premature cranial suture fusion (craniosynostosis) provide one rou

36 Since noggin misexpression prevents cranial suture fusion in vitro and in vivo, we suggest t

37 nai1 and Snai2 mutations to enhance aberrant cranial suture fusion, demonstrating that genetic intera

38 Craniosynostosis, or premature cranial suture fusion, results in an abnormal skull shap

39 ribe the pathways and processes that lead to cranial suture fusion.

40 numerous syndromes associated with premature cranial suture fusion.

41 tudy the biomolecular mechanisms that govern cranial suture fusion.

42 mes of craniosynostosis (premature fusion of cranial sutures) have homologues in the CeTwist pathway.

43 replication with growth, chondrogenesis, and cranial suture homeostasis.

44 Over-expression of Nell1 in the developing cranial sutures in both human and mouse induces craniosy

45 Premature closure of cranial sutures in intramembranous ossification is a fea

46 ex craniosynostosis (premature fusion of the cranial sutures) in humans and mice.

47 raniosynostosis, the premature fusion of the cranial sutures, is a heterogeneous disorder with a prev

48 e was de novo formation of tissue-engineered cranial suture, microscopically reminiscent of the adjac

49 enital disorder of premature ossification of cranial sutures, occurring in one of approximately every

50 In the mutants, premature fusion of cranial sutures occurs at early postnatal stages.

51 We therefore, investigated why cranial sutures of same tissue origin adopt a different

52 Interestingly, the cranial sutures of the mutant mice showed normal anatomi

53 ostosis, the premature fusion of one or more cranial sutures of the skull, provides a paradigm for in

54 with the pathways that are known to regulate cranial suture patency.

55 T/E dimers plays a central role in governing cranial suture patency.

56 The tissue-engineered cranial suture showed radiolucency on radiographic image

57 ricular surfaces, pubic symphyseal face, and cranial sutures, to produce a multifactorial narrower ag

58 Premature closure of cranial sutures, which serve as growth centers for the s