ライフサイエンスコーパス: crawl

1 performed in the course of fictive crawling (crawling).

2 ch abdominal segment in the direction of the crawl.

3 contractions that allow fruit fly larvae to crawl.

4 raight crawls, pauses, turns, and redirected crawls.

5 ion from the substrate in the course of cell crawling.

6 lved in E-selectin-mediated slow rolling and crawling.

7 is involved in Mac-1-dependent intravascular crawling.

8 is a sufficient signal to induce healing by crawling.

9 tion of the EGFR, which triggers movement by crawling.

10 ls to constrain behavior to simple, rhythmic crawling.

11 P) as linear actuators to enable directional crawling.

12 new feature in our emerging understanding of crawling.

13 fly locomotion, but also crucial for larval crawling.

14 (LFA-1)- versus CD11b/CD18 (Mac-1)-mediated crawling.

15 es (67.4 +/- 9.6 mum), resembling neutrophil crawling.

16 local interoscillator coupling contribute to crawling.

17 rent from electrically evoked or spontaneous crawling.

18 intersegmental phase delays appropriate for crawling.

19 nderstanding of the mechanics of caterpillar crawling.

20 nsory inputs resulted in cessation of larval crawling.

21 reas cell 257 is an interneuron dedicated to crawling.

22 scillated with swimming also oscillated with crawling.

23 t characterize key behaviors such as forward crawling.

24 hrough the lymphatic endothelium and luminal crawling.

25 istaltic waves of muscle contractions during crawling.

26 ed for the different elements of exploratory crawling.

27 twice as many cells oscillated in-phase with crawling (188) compared with swimming (90).

28 cic and abdominal segments that generate the crawls; (2) asymmetrical output that is uniquely initiat

29 To crawl, a cell must adhere to the substrate, while protru

30 During reverse crawls, abdominal body wall movements are powered by pha

31 During forward crawls, abdominal body wall movements are powered by sim

32 elated with NMJ size and regulated by larval crawling activity, synapse excitability, postsynaptic re

33 k56), both of which are required to suppress crawling activity-dependent NMJ growth.

34 etween actomyosin cable contraction and cell crawling acts as a large-scale regulator to control the

35 sary and sufficient to initiate and maintain crawling after swimming.

36 Migrating OPCs crawl along and jump between vessels.

37 After the initial arrest, CD8 TE actively crawl along liver sinusoids and probe sub-sinusoidal hep

38 After EC migration, neutrophils crawl along pericyte processes to gaps between adjacent

39 cell interior, enabling cells to adhere and crawl along surfaces.

40 n lymphatic vessels, allowing neutrophils to crawl along the lumen of the lymphatic endothelium in an

41 spleen for the CNS where they first roll and crawl along the luminal surface of leptomeningeal vessel

42 roscopy that blood monocytes and neutrophils crawling along and adhering to the venous endothelium pr

43 ophils into lymphatic vessels and subsequent crawling along the luminal side of the lymphatic endothe

44 Ly6C(lo) monocytes, patrol blood vessels by crawling along the vascular endothelium.

45 The tip of each filopodium crawls along ECM fibers, tugs the surrounding fibers, an

46 that are defective in transitioning between crawl and swim behavior, we identified unc-79 and unc-80

47 ugh venular walls, such as leukocyte luminal crawling and cellular and molecular changes in leukocyte

48 tadhesion phase, which involves intraluminal crawling and diapedesis to the extravascular space, rema

49 de distinct forms of excitatory drive during crawling and differ in key transmission properties.

50 cremaster muscle, we separately examined the crawling and emigration patterns of monocytes and neutro

51 under dynamic flow conditions CXCL12-induced crawling and endothelial transmigration of Th1 cells was

52 ntigen-1/alphaLbeta2 integrin for subsequent crawling and extravasation.

53 Depletion of LARG decreases leukocyte crawling and inhibits TEM.

54 KT2 is important for neutrophil adhesion and crawling and neutrophil-platelet interactions on activat

55 entical sensory inputs that sometimes elicit crawling and other times swimming.

56 ack loop promotes ICAM-1-mediated neutrophil crawling and paracellular transmigration.

57 rupted at intervals by pause turns that halt crawling and redirect the trajectory of movement.

58 otor neuron bursting and coordination during crawling and restoring cacophony selectively in two pair

59 m food, resulting in longer bouts of forward crawling and suggesting that worms can use noise to modi

60 ward thrust during movement and suggest that crawling and swimming are similar processes, a compariso

61 s biogenic amines to switch between distinct crawling and swimming gaits.

62 H1(-/-) leukocytes were deficient in in vivo crawling and TEM in the postcapillary venules.

63 Leukocyte crawling and transendothelial migration (TEM) are potent

64 lling on selectins but impaired intraluminal crawling and transendothelial migration.

65 cytosis, endothelial adhesion, intravascular crawling and transmigration.

66 A combination of crawling and undulation gaits allowed this robot to navi

67 Both crawling and walking delivered a significant number of r

68 Alternation between crawls and turns is an intrinsic property of the abdomin

69 rmines the time-dependent transition between crawls and turns.

70 The physical mechanism of plasmin action (crawling) and avoidance of inhibition is defined.

71 Sh3bp2-/- neutrophils failed to adhere, crawl, and emigrate out of the vasculature in response t

72 ce signals through PSGL-1 displayed aberrant crawling, and blockade of this domain protected mice aga

73 BBB endothelium supports neutrophil arrest, crawling, and diapedesis under physiological flow in vit

74 othelial expression of ICAM-1, intravascular crawling, and extravasation.

75 Wounds can also heal by cell crawling, and my colleagues and I have shown previously

76 helps to explain the inherent flexibility of crawling, and provides a foundation for understanding ot

77 f Shp1 to study neutrophil arrest, adhesion, crawling, and transendothelial migration in vitro and in

78 Leukocyte adhesion, crawling, and transmigration are regulated by clustering

79 n, postadhesion strengthening, intravascular crawling, and transmigration, as each step necessitates

80 tangential surface drag coefficients during crawling are approximately 222 and 22, respectively, and

81 1-dependent slow rolling and Mac-1-dependent crawling are defective in P-Rex1(-/-) leukocytes, wherea

82 Thus, mechanisms underlying leukocyte crawling are important in regulating the inflammatory re

83 Amoeboid sperm crawl around fertilized eggs to the spermatheca--a convo

84 potentials of DsRed(+) cells-they constantly crawled around hair follicles via amoeba-like movements

85 viscous drag forces, which are higher during crawling as compared to swimming in an aqueous buffer so

86 disease-causing chytrid fungi, which we show crawl at >30 microm/min with actin-filled pseudopods.

87 c fields, we show that C. elegans prefers to crawl at specific angles to the direction of the electri

88 ter a vertically confined space, cockroaches crawled at velocities approaching 60 cms(-1), despite bo

89 F-beta- and integrin-dependent lamellipodial crawling at the leading edges of the epidermal tongue.

90 We quantified crawling at the organism, segment, and muscle levels.

91 pedal (man and chicken) or quadrupedal mode (crawling-baby and cat).

92 t when the CNS was exposed to dopamine (DA), crawling became the exclusive locomotor pattern produced

93 expression in motor neurons regulates larval crawling behavior in a developmental stage-specific mann

94 simplex virus infection show a steady-state crawling behavior in between keratinocytes.

95 Long-range crawling behavior in CD14(dim)CD16(+) monocytes was abro

96 tical, we also showed that changes in larval crawling behavior in response to either hypoxia or hyper

97 n region between different types of observed crawling behavior in the dynamical phase diagram, such a

98 Analysis of the network that controls crawling behavior in the leech has clearly indicated tha

99 levels of biological organization, from the crawling behavior of Caenorhabditis elegans to the contr

100 The characteristic crawling behavior of Drosophila larvae consists of a ser

101 Here, we use the crawling behavior of the nematode Caenorhabditis elegans

102 Unlike T cells, which displayed vigorous crawling behavior on the endothelium, B cells remained s

103 A long-range crawling behavior, similar to the "patrolling" behavior

104 monstrated ICAM-1-dependent shape-change and crawling behavior.

105 as both necessary and sufficient for fictive crawling behavior.

106 step elongation-contraction cycle underlying crawling behavior.

107 oked synaptic transmission and alters larval crawling behaviour.

108 and myosin inhibitors affected the speed of crawling but not directed motion, whereas pertussis toxi

109 rsibly with a sucrose block) prevented overt crawling, but not swimming.

110 Many animal cells initiate crawling by protruding lamellipodia, consisting of a den

111 e motility mechanisms: horizontally oriented crawling, by which the bacterium moves lengthwise with h

112 technique shows that the internal organs of crawling caterpillars slide past the body walls like pis

113 ize internal soft-tissue movements in freely crawling caterpillars.

114 we present a simplified physical model of a crawling cell, consisting of a droplet of active polar f

115 y resembles that seen in many other types of crawling cell, movement is generated by modulation of a

116 he solutions demonstrate that in the rapidly crawling cell, myosin concentrates at the rear boundary

117 nched network found at the leading edge of a crawling cell.

118 assembly powers protrusion in other types of crawling cell.

119 e biogenesis , plasma-membrane protrusion in crawling cells , and membrane trafficking from the Golgi

120 In addition, many crawling cells can translocate when myosin is inhibited

121 ations shows that leading edge protrusion in crawling cells increases membrane tension, which constra

122 In most crawling cells protrusion is driven by highly regulated

123 In addition, some crawling cells when plated onto a stiff substrate will n

124 Inside of crawling cells, NMIIA-Fs form large macromolecular ensem

125 Some crawling cells, such as fish keratocytes, maintain a rou

126 usually produces finger-like projections of crawling cells.

127 a principal regulator of pseudopod growth in crawling cells.

128 direct role in actin network disassembly in crawling cells.

129 ary nucleator of new actin filaments in most crawling cells.

130 Whether to spread on a surface or to crawl, cells must apply traction forces to the underlyin

131 During cytokinesis or eukaryotic cell crawling, contractile forces are generated inside the ce

132 sy regime cellular events such as spreading, crawling, contracting, and invading.

133 ng force generated during either swimming or crawling correlate well with previously described gait-s

134 urons was performed in the course of fictive crawling (crawling).

135 We use sequential large-scale crawl data to empirically investigate and validate the d

136 itinated proteins, neurodegeneration, larval-crawling defect and early lethality.

137 d BMP signaling, synaptic growth, and larval crawling defects.

138 Movement by crawling depends on signaling by the EGF receptor (EGFR)

139 Using the quantitative model of larval crawling developed here we use the mutant-specific param

140 ractors corresponding to abrupt reversals in crawling direction.

141 al requirement for ROCK in intralymphatic DC crawling during steady-state and inflammation.

142 PDI is required for neutrophil adhesion and crawling during tumor necrosis factor-alpha-induced vasc

143 Specifically, a transition from crawling dynamics to flipping behavior occurs at a Young

144 Brief excitation of CV motoneurons during crawling episodes resets the rhythmic activity of DE-3,

145 cells and may explain reports of cells that crawl even when their myosin activity is compromised.

146 that matched periods observed during fictive crawling, even when potential ascending inputs from craw

147 In the absence of crawling, few neutrophils maintained adhesive interactio

148 esults explain how the nucleus is moved in a crawling fibroblast and raise the possibility that force

149 rusion cycles and handmirror morphology of a crawling fibroblast, and others the steady gliding motil

150 - 0.9%, adhered/total interacting), and they crawl for significantly longer distances (147.3 +/- 13.4

151 ingly, after TNF-alpha activation, monocytes crawled for significantly shorter distances (67.4 +/- 9.

152 omotion when touched on the head, while they crawl forward when touched on the tail.

153 Durotaxis is the tendency of cells to crawl from soft to stiff matrix, and durotaxis of primar

154 of the main forces governing the C. elegans crawling gait on lubricated surfaces have been scarce, p

155 During the crawling gait, evoked by large external loads, comparabl

156 both LFA-1 and Mac-1 contribute to monocyte crawling; however, the LFA-1-dependent crawling in unsti

157 The package is divided into web-crawling, HTML-cleaning, de-identification and informati

158 Animal cells migrating over a substratum crawl in amoeboid fashion; how the force against the sub

159 Mac-1 alone was responsible for neutrophil crawling in both unstimulated and TNF-alpha-activated ve

160 ersegmental phase delays, we induced fictive crawling in isolated whole nerve cords using dopamine (D

161 We show that TFP-mediated crawling in Pseudomonas aeruginosa consistently alternat

162 copy, we found immature B cells entering and crawling in sinusoids; these immature B cells were displ

163 one ganglion was removed from its neighbors, crawling in that ganglion emerged robust and stable, und

164 activity, is sufficient to activate fictive crawling in the medicinal leech, and can exert its actio

165 generators (CPGs) control both swimming and crawling in the medicinal leech.

166 By eliciting swimming and crawling in the same preparation, we were able to identi

167 ocyte crawling; however, the LFA-1-dependent crawling in unstimulated venules becomes Mac-1 dependent

168 We studied rhythmic behavior--larval crawling--in the genetically and developmentally tractab

169 ed, generates propagating activity as during crawling inDrosophilalarvae.

170 er experiments were conducted with a robotic crawling infant and an adult performing a walking sequen

171 utine of this kind, performing straight line crawling interrupted at intervals by pause turns that ha

172 Neutrophils crawled into the injury from significant distances throu

173 able alkali fly, Ephydra hians, deliberately crawls into the alkaline waters of Mono Lake to feed and

174 Cell crawling is an inherently physical process that includes

175 ently, neutrophil adhesion is increased, but crawling is decreased.

176 We showed that Drosophila larval crawling is made up of a series of periodic strides.

177 n previous work, we found that as C. elegans crawls, its body moves through a "shape space" in which

178 ters obtained from the trajectories of a few crawling larvae.

179 d with DA, neighboring ganglia began to show crawl-like bursting, with motoneuron spikes/burst greate

180 initially poorly organized, and coordinated crawling-like behavior gradually emerges over the subseq

181 maximum intraburst firing frequencies during crawling-like motor patterns in semi-intact animals.

182 The embryo continues to exhibit bursts of crawling-like sequences until shortly before hatching, w

183 ructured arena allowed C. elegans to perform crawling locomotion in a controlled liquid environment.

184 Crawling locomotion of eukaryotic cells is achieved by a

185 ate the nicotinergic signaling that controls crawling locomotion of KCs.

186 Consistent with the role of Mac-1 in crawling, Mac-1 block (compared with LFA-1) was also sig

187 report a novel visceral-locomotory piston in crawling Manduca sexta larvae, in which the gut slides f

188 Intracellular crawling may contribute to optimal lymphocyte positionin

189 as a mechanically passive substrate for the crawling mesoderm and to secrete various growth factors

190 s considered to form a simpler, yet similar, crawling motility apparatus.

191 Crawling motion is ubiquitous in eukaryotic cells and co

192 Crawling motion mediated by retrograde and direct waves,

193 The crawling motion of Dictyostelium discoideum on substrata

194 processes in eukaryotic cells, including the crawling motion of the whole cell, rely on the growth of

195 , and those DsRed(+)/Ly6G(+) cells exhibited crawling motion with a higher velocity compared with the

196 ndritic and the axonal compartment of larval crawling motoneurons.

197 ned that R3b-1 modulates the cycle period of crawl motor activity.

198 e that DA is sufficient to activate the full crawl motor program and that the kernel for crawling res

199 Research on the circuit that controls the crawling motor behavior in leeches indicated that motone

200 Crawling movement in eukaryotic cells requires coordinat

201 The crawling movement of nematode sperm requires coordinatio

202 resulted in flattening of the T cells and a crawling movement on the FLS surface.

203 nding to its receptor ( approximately 10 nM) crawl much less frequently when DeltaC/C is 0.05 than wh

204 icients to predict the forces generated by a crawling nematode.

205 These results show that the swimming and crawling networks are driven by both multifunctional and

206 The crawling neutrophils required the platelet-paved endothe

207 (2) integrin clusters at the leading edge of crawling neutrophils, allowing capture of circulating er

208 Crawling neutrophils, although preferentially crossing t

209 Crawling of eukaryotic cells on flat surfaces is underla

210 ess triggered GEF-H1-dependent spreading and crawling of neutrophils and relocalization of GEF-H1 to

211 ening, spreading, and directed mechanotactic crawling of PMNs under flow conditions-involved HPK1 in

212 scade, which involves rolling, sticking, and crawling of the leukemic cells on the endothelium.

213 e recordings, we demonstrated "intracellular crawling" of lymphocytes entering into one endothelial c

214 Many bacteria swim through liquids or crawl on surfaces by rotating long appendages called fla

215 on distribution along the membrane of a cell crawling on a flat substrate.

216 Thus, beta2 integrin-mediated neutrophil crawling on endothelial ICAM-1 and ICAM-2 is a prerequis

217 For cells crawling on hard surfaces, significant insights into mot

218 In this model of neutrophils crawling on immobilized platelets, very few NETs were ob

219 ear stress, cell morphology alterations, and crawling on intercellular adhesion molecule 1 (ICAM-1)-e

220 expressed ICAM-1 and DC-expressed ROCK in DC crawling on lymphatic endothelium.

221 embly in the lamellipodium in adherent cells crawling on planar 2-dimensional (2D) substrates.

222 dulation frequency, and wavelength of worms, crawling on surfaces show nonmonotonic behavior with inc

223 ditis elegans, between swimming in water and crawling on surfaces, adapts its locomotory gait to surr

224 h act downstream of capturing, adhesion, and crawling on the blood vessel wall and require Galphai si

225 -induced neutrophil spreading and subsequent crawling on the endothelium to sites of transmigration.

226 the liver microvasculature of healthy mice, crawling on the luminal side of endothelial cells, but t

227 t coordinated motion into the void by active crawling on the substrate and by constricting a supracel

228 orces and the nematode's bending force while crawling on the surface of agar gels within a preexistin

229 rin-mediated events such as rapid arrest and crawling on the surface of the endothelium and transmigr

230 membrane, and we detected detached podocytes crawling on the surface of the tubular epithelium and oc

231 ations in shear-resistant adhesion to, or in crawling on, primary endothelial cells under physiologic

232 As a worm crawls on an agar surface, we found that substrate visco

233 ns: it swims in low viscosity liquids and it crawls on the surface of an agar gel.

234 gh these arrested T cells polarize and start crawling, only few remain firmly adherent over time.

235 to swim; depolarizing it biases the leech to crawl or to delay swimming.

236 Long before infants reach, crawl or walk, they explore the world by looking: they l

237 In just 1 min of crawling or walking, 10(3)-10(4) resuspended FBAPs can d

238 revention of Ly6C(low) monocyte development, crawling, or retention in Nr4a1(-/-), Itgal(-/-), and Tl

239 coordination of the segmentally distributed crawl oscillators that makes this multifunctional neuron

240 g, even when potential ascending inputs from crawl oscillators were removed.

241 activation and coordination of the segmental crawl oscillators, or unit burst generators, are depende

242 downregulate adhesion and polarity proteins, crawling over and between neighboring cells to converge

243 eo-taped and quantified for locomotion (e.g. crawling pattern and speed) using ImageJ software.

244 ccurately account for the complex and unique crawling patterns exhibited by individual Drosophila lar

245 n-blocking Abs, we show that these different crawling patterns were due to CD11a/CD18 (LFA-1)- versus

246 kind that consists of sequences of straight crawls, pauses, turns, and redirected crawls.

247 Egyptian fruit bat and big brown bat, which crawled randomly in three different open-field arenas.

248 Naive CD8(+) T cells crawled rapidly at steady state but arrested immediately

249 te that neutrophil arrest, polarization, and crawling required G-protein-coupled receptor-dependent a

250 crawl motor program and that the kernel for crawling resides within each segmental ganglion.

251 Crawling results from successive bouts of elongation and

252 labeled ground truth, initial seeds and the crawling results reported in this article.

253 The expression of swimming versus crawling rhythms is regulated by sensory input.

254 the fabrication of machines, we developed a crawling robot that folds itself.

255 ctivity are poorly organised and coordinated crawling sequences only begin to appear after a further

256 h of execution till the end of the 20-h long crawling session as compared with the cumulative precisi

257 h of execution till the end of the 20-h long crawling session as compared with the cumulative precisi

258 crawling to swimming and to inhibit a set of crawl-specific behaviors.

259 Our experiments reveal that crawling speed is an increasing function of both cell si

260 e-derived spermatids that cannot activate to crawling spermatozoa, although spermatids from mutant ma

261 activate from a round spermatid to a mature, crawling spermatozoon.

262 y, monocytes appeared to flutter rather than crawl, such that the 3D surface topology of individual c

263 ated chemokine-induced adhesive filopodia on crawling T lymphocytes that scan the endothelial surface

264 h the existing state-of-the-art adaptive web crawling technology.

265 in novel, open-source data sets through web crawling, text mining, and social media analytics, prima

266 rns; and (3) an intermittent interruption to crawling that determines the time-dependent transition b

267 contractile waves during cell spreading and crawling that is only dependent on stick-slip adhesion a

268 fibroblasts showed that during spreading and crawling the lamellipodium undergoes periodic contractio

269 The alternative option, blindly crawling the whole web, has proven inefficient and unaff

270 During crawling, the calculated internal bending force is time-

271 Diverse eukaryotic cells crawl through complex environments using distinct modes

272 lapse imaging of neutrophil-like HL-60 cells crawling through collagen matrices.

273 migration under flow conditions and reduced crawling time, velocity, and lateral migration distance

274 necessary and sufficient to transition from crawling to swimming and to inhibit a set of crawl-speci

275 t in HEVs but showed perturbed intravascular crawling to transmigration sites and compromised diapede

276 lumenally adhered monocytes and neutrophils crawl toward locations that support transmigration.

277 tro evidence, is dispensable for sensing and crawling toward wound cues.

278 nematode Caenorhabditis elegans deliberately crawls toward the negative pole in an electric field.

279 ted endothelial cells (ECs), tight adhesion, crawling towards EC junctions and transendothelial migra

280 rophil adhesion in vivo; however, neutrophil crawling, transmigration, and chemotaxis were reduced in

281 e receptors migrate against this gradient by crawling under the agarose spots towards their centre.

282 luding ano-genital sniffs, allogrooming, and crawl-under/over behaviors) than control mice.

283 each DE-3 burst, further confirming that the crawl unit burst generator exists in the single ganglion

284 Such experiments show that crawling uses a combination of actin treadmilling (polym

285 tant for neutrophil recruitment, reduced the crawling velocities of neutrophils within vessels, and m

286 chanism to regulate surface contact area and crawling velocity within different environments.

287 hes between distinct forms of locomotion, or crawling versus swimming, when transitioning between sol

288 When crawling was blocked by inhibition of EGFR signaling, th

289 the increased Mac-1 adhesiveness, neutrophil crawling was impaired in CD45E613R mutant compared with

290 Neutrophil crawling was mediated by endothelial ICAM-1 and ICAM-2 a

291 mbrane potential of CV was manipulated while crawling was monitored through the rhythmic activity of

292 ntitative analysis indicated that DA-induced crawling was not significantly different from electrical

293 plain force production during nematode sperm crawling, we constructed a mathematical model that simul

294 cific parameters to robustly simulate larval crawling, which allows estimating the feasibility of lab

295 mpetent to produce DA-induced robust fictive crawling, which typically lasted uninterrupted for 5-15

296 idence for a widely distributed mode of cell crawling with a single evolutionary origin.

297 n characteristics from free swimming to slow crawling with increasing confinement so that it was not

298 ocal oscillator coupling, we induced fictive crawling (with DA) in a single oscillator within a chain

299 ed mode of locomotion--"body-friction legged crawling" with body drag, friction-dominated leg thrust,

300 ocytes have been shown to undergo long-range crawling within the lumen of the microvasculature, which