ライフサイエンスコーパス: crescent

1 and agricultural colonists from the Fertile Crescent.

2 icultural village development in the Fertile Crescent.

3 rley and early forms of wheat in the Fertile Crescent.

4 (BF-1) expands from nasal retina into the VT crescent.

5 nificantly reduced expression in the cardiac crescent.

6 na corresponding to the myopic peripapillary crescent.

7 he founder crops domesticated in the Fertile Crescent.

8 olated from other populations of the Fertile Crescent.

9 c, when farming expanded west of the Fertile Crescent.

10 as most prominent nasally and in eyes with a crescent.

11 3.9) linked to the percentage of glomerular crescents.

12 oliferation, which ultimately forms cellular crescents.

13 ach dimer contains two separate and complete crescents.

14 these buttons were packed with budding viral crescents.

15 tion, with macrophages also most numerous in crescents.

16 d this was associated with larger optic disc crescents.

17 e precursors of cells that populate cellular crescents.

18 docytes and in podocytes entrapped in pseudo-crescents.

19 At day 15 of disease, WT mice had glomerular crescents (37%+/-5%), severe proteinuria, and a 6-fold i

20 Here we show that Crescent, a dorsal protein, can compensate for the loss

21 h in situ hybridization with a riboprobe for Crescent, a marker of the hypoblast.

22 ar crescents and close to the edge or rim of crescents; a similar labeling pattern was found for the

23 d in an extra-embryonic region, the germinal crescent, after approximately 18 h of incubation.

24 increased glomerular thrombosis, glomerular crescents, albuminuria, serum urea, and glomerular neutr

25 We now find that Crescent also regulates the BMP pathway.

26 s in the Southern Levant part of the Fertile Crescent, an area with a high proportion of the total ge

27 genitor cells were isolated from the cardiac crescent and 2 subsequent stages of heart development: t

28 stications of barley; one within the Fertile Crescent and a second 1,500-3,000 km farther east.

29 to the origin of barley--one in the Fertile Crescent and another farther east, possibly at the easte

30 inants Prospero and Numb localize in a basal crescent and are partitioned from neuroblasts to their d

31 ,000 years before the present in the Fertile Crescent and became a founder crop of Neolithic agricult

32 When co-injected, Crescent and Chordin proteins greatly synergized in the

33 ) mesoderm and in pharyngeal endoderm at the crescent and early somite stages.

34 t cultivated 10,500 years ago in the Fertile Crescent and is one of the founder crops of Eurasian agr

35 f A17 was also required for the formation of crescent and IV structures.

36 to regulate early expression in the cardiac crescent and later segmental expression in the developin

37 c pastoral agriculturalists from the Fertile Crescent and Northern Africa, as well as more recent mig

38 n wheat landraces collected from the Fertile Crescent and surrounding areas carried the mutation (C)

39 outside factories and inside factories near crescents and close to the edge or rim of crescents; a s

40 eveloped diffuse proliferative GN with focal crescents and glomerulosclerosis.

41 This mutant, however, developed crescents and had normal A11 localization despite failin

42 ffold protein-coated membranes that resemble crescents and immature virions devoid of viroplasm were

43 us homologs, contributes to the formation of crescents and immature virions.

44 r) mice had a complete absence of glomerular crescents and marked reductions in glomerular hypercellu

45 er, viral membrane formation was delayed and crescents and occasional immature forms were detected on

46 teins known to be necessary for formation of crescents and the only one synthesized early in infectio

47 synthetic procedures for the preparation of crescent (and helical) aromatic oligoamides developed in

48 nsiently during establishment of the cardiac crescent, and extinguished from the heart before CNC inv

49 lation of large virosomes, detached membrane crescents, and empty immature virions.

50 omerular injury, the development of cellular crescents, and the activation and proliferation of PECs

51 ins are induced at 12 h postinfection (hpi), crescents appear at the periphery of the electron-dense

52 ch as Bmp2, Bmp7, Hex and the Wnt antagonist crescent are affected during early gastrulation.

53 The crescents are highly unusual, open-ended membranes, and

54 Crescents are rare in primary membranous nephropathy and

55 nd that in pheromone-treated cells, receptor crescents are visible before detectable polarization of

56 sequestering Wnts, such as Frz-B, WIF-1 and Crescent, are poor mimics of the inductive and patternin

57 defined genes encoding the sFRPs Frzb-1 and Crescent as transiently and locally expressed in the pri

58 icated a close association of A17 and D13 in crescents, as well as in vesicular structures when cresc

59 ntain numerous stemmed projectile points and crescents associated with a variety of marine and aquati

60 0 (P </= .001) and presence of peripapillary crescent at all locations except T1500 and T2250 (P </=

61 ents SEC-5, -6, -8, and -15 form a delimited crescent at the apical plasma membrane.

62 neage cells, BASL accumulates in a polarized crescent at the cell periphery before division, and then

63 arrest and crawl slowly with a dense ICAM-1 crescent at the leading edge.

64 One consisted of short crescents, at the surface of dense masses of viroplasm,

65 ees centrally, and a far temporal peripheral crescent bilaterally, and ERGs were nondetectable.

66 the cell shape of Parachlamydia and that the crescent body is not a developmental stage, but an artef

67 essential role not only in the formation of crescents but also in their subsequent enclosure to form

68 uggest that it participates in elongation of crescents by the addition of ER membrane to the growing

69 folding proteins are bound inside the large crescent cleft, thus enabling their access to inward-fac

70 The result is a bubble-crescent configuration, which alternates between two deg

71 The crescents consist of a lipoprotein membrane and an outer

72 Crescents consisting of a single lipoprotein membrane wi

73 We previously found that crescents derive from the aberrant proliferation and mig

74 n BM was transferred from WKY to Lewis rats, crescents developed in 35 +/- 9% of glomeruli 10 d after

75 The Fertile Crescent domestication contributed the majority of diver

76 communities emerged in parts of the Fertile Crescent during the tenth millennium and early ninth mil

77 l basement membrane and populated glomerular crescents during the early phases of cellular crescent f

78 For this reason and the crescent employment of mass spectrometry (MS) techniques

79 Crescents enlarge to form spherical immature virions, wh

80 n begins at the lateral sides of the cardiac crescent, excluding early differentiating regions, and c

81 sing that began in 2011, the greater Fertile Crescent experienced the most severe drought in the inst

82 In the eastern Fertile Crescent exploitation of legumes, fruits, nuts, and gras

83 e a primary mouth to embryos in which Frzb-1/Crescent expression has been inhibited.

84 ;face transplants', we show that frzb-1 and crescent expression is specifically required in the prim

85 Crescent expression was increased by the BMP antagonist

86 apillary proliferation, sometimes resembling crescents, following rapid and severe podocyte loss.

87 1 versus 8.0 +/- 1.9 controls; P < 0.05) and crescent formation (0% CNTO 1081 versus 60% controls; P

88 noncomplementing cell lines with defects in crescent formation and A11 localization.

89 ignificantly reduced glomerular necrosis and crescent formation and abrogated monocyte, macrophage, a

90 of nephrotoxic nephritis resulted in reduced crescent formation and decreased proteinuria.

91 wo-domain architecture and functions in both crescent formation and its enclosure to form immature vi

92 Crescent formation and renal MMP and growth factor expre

93 ange of kidney lesions, including glomerular crescent formation and renal tubule defects in early dis

94 es in the glomeruli; ii) marked reduction in crescent formation and sclerotic glomeruli; iii) decreas

95 ytes/macrophages for glomerular necrosis and crescent formation in a renal ANCA-associated vasculitis

96 unction, which, histologically, manifests as crescent formation in most glomeruli.

97 Crescent formation requires a group of proteins that are

98 nts, as well as in vesicular structures when crescent formation was prevented.

99 interstitial nephritis, increased glomerular crescent formation with macrophage and neutrophil infilt

100 ion of glomerular leukocytes, and glomerular crescent formation).

101 rescents during the early phases of cellular crescent formation, accounting for at least one-fourth o

102 s, focal necrotizing glomerulonephritis with crescent formation, and glomerular infiltration by T cel

103 kappaB activation positively correlated with crescent formation, and nuclear phospho-p65 staining sho

104 phi infiltration in the glomeruli, prevented crescent formation, and reversed renal function impairme

105 zed by proliferative glomerulonephritis with crescent formation, and tubulointerstitial disease.

106 xhibited pronounced glomerulonephritis, with crescent formation, as well as tubulointerstitial diseas

107 membranes, which resembled the beginnings of crescent formation, at their periphery.

108 lomerular proliferative lesions with de novo crescent formation, findings that are linked with decrea

109 e recently identified as being essential for crescent formation, including the A6 protein of vaccinia

110 he density of CCL18(+) cells correlated with crescent formation, interstitial inflammation, and impai

111 While a cognate N domain is not required for crescent formation, it is required for virion formation,

112 ackground leads to significant reductions in crescent formation, macrophage infiltration, Fc receptor

113 esangial expansion, capillary proliferation, crescent formation, necrosis, wire loops, fibrosis, tubu

114 o other proteins that are required for viral crescent formation, profoundly decreased the stability o

115 an A2AR agonist, the glomerular cellularity, crescent formation, sclerotic glomeruli, and tubulointer

116 uding inhibition of albuminuria and cellular crescent formation, similar to the renal benefits observ

117 ionally, the connexin 43+/- mice showed less crescent formation, tubular dilation, monocyte infiltrat

118 Trp53-deficient mice, with the exception of crescent formation, which was not influenced by nutlin-3

119 l cell TLR4 stimulation increases glomerular crescent formation, with a mean of 21% and 25% in the tw

120 spicuous at sites of glomerular necrosis and crescent formation, with macrophages also most numerous

121 nd focal necrotizing glomerulonephritis with crescent formation.

122 iscovered that it plays an important role in crescent formation.

123 acement, vacuolization, and hypertrophy with crescent formation.

124 cterized by glomerular necroinflammation and crescent formation.

125 ent parietal epithelial cell hyperplasia and crescent formation.

126 isite for PEC proliferation and migration in crescent formation.

127 We show that Frzb-1/Crescent function locally promotes basement membrane dis

128 primary mouth) is seen after loss of Frzb-1/Crescent function to that seen after temporally and spat

129 of ecogeographical conditions in the Fertile Crescent, has valuable "left behind" adaptive diversity

130 roposition from its parental gene, Infertile crescent (Ifc), and integrated into heterochromatic regi

131 However, no viral membrane crescents, immature virions, or mature virions were prod

132 e depletion reduced the number of glomerular crescents, improved renal function, and reduced proteinu

133 emained restricted to a cortical cytoplasmic crescent in blastomeres of 2-, 4- and 8-cell embryos.

134 MOEP19 cortical oocyte domain as a cortical crescent in blastomers suggests an intrinsic pre-pattern

135 lizes like the protein it encodes in a basal crescent in mitosis.

136 n the Mediterranean Basin and in the Fertile Crescent in relation to the past and current climate.

137 fferentially to the nucleus and a peripheral crescent in self-renewing cells and their sisters after

138 ical defect matches the myopic peripapillary crescent in size and shape, indicating that fill-in of t

139 As early farming spread from the Fertile Crescent in the Near East around 10,000 years before the

140 injection of anti-MPO IgG induced glomerular crescents in >60% of glomeruli in 129S6/SvEv and CAST/Ei

141 of nephrotoxic globulin, WKY rats developed crescents in 80 +/- 2% of glomeruli at day 10, whereas n

142 The presence of glomerular crescents in allograft biopsies had a significant negati

143 helial cells (PEC) are major constituents of crescents in crescentic glomerulonephritis.

144 te mutant Canoe protein fails to form apical crescents in dividing neuroblasts in vivo, and the lack

145 on and reduce the frequency and extension of crescents in extracapillary GN.

146 ocess, inhibits the formation of apical aPKC crescents in neuroblasts.

147 contribute to the formation of both cellular crescents in rapidly progressive GN and sclerotic lesion

148 ontains nonglycosylated proteins, appears as crescents in the cytoplasm, and delimits immature and ma

149 In NTN, the ratio of crescents in the transplanted kidney to the native kidne

150 aits of species originating from the Fertile Crescent, including those for which there is archaeologi

151 emarkably, N1 also synergizes with WIF-1 and Crescent, indicating that N1 signals independently of C1

152 a-catenin signaling by Dickkopf-1 (Dkk-1) or Crescent initiates cardiogenesis in vertebrate embryos.

153 ent trabecular outflow system, so there is a crescent interest in increasing trabecular meshwork outf

154 in expansion of agriculture from the Fertile Crescent into diverse environments across the Mediterran

155 In sum, Crescent is a new component of the D-V pathway, which fu

156 Crescent is a secreted Frizzled-Related Protein (sFRP) k

157 The formation of a myopic crescent is accompanied by loss of metabolic activity in

158 Crescent knock-down increased the expression of BMP targ

159 irus-induced spherule-like structures, while crescent-like structures are formed in ESCRT-III deletio

160 ing events are visualized by biosensors in a crescent-like zone at the plasma membrane.

161 Thus, Crescent loss-of-function is compensated by increased ex

162 tivity (c-FLI) in the central, external, and crescent lPBN, and there was a strong correspondence bet

163 we hypothesized that urinary sCD163 shed by crescent macrophages correlates with active glomerular i

164 e N-terminal or central loop region affected crescent maturation and the immature virion (IV)-->matur

165 ading to impaired differentiation and failed crescent maturation.

166 n-associated collapses (for example, Fertile Crescent, Maya and Anasazi) or the lack thereof (Japan a

167 le is known regarding the composition of the crescent membrane or its mode of formation.

168 L2 mutant revealed abortive formation of the crescent membrane.

169 indicated that A11, like L2, associated with crescent membranes and immature virions during normal in

170 n factory regions or with formation of viral crescent membranes and infectious intracellular mature v

171 Crescent membranes are the first viral structures that c

172 inia virus morphogenesis, the association of crescent membranes with electron-dense granular material

173 aceous material with the concave surfaces of crescent membranes, an early step in viral morphogenesis

174 in poxvirus morphogenesis, the formation of crescent membranes, occurs within cytoplasmic factories.

175 required for the formation or elongation of crescent membranes.

176 lular membranes but by forming and extending crescent membranes.

177 epend on autocrine Fgf8 signaling in cardiac crescent mesoderm.

178 egmental necrotizing glomerular lesions with crescents, mimicking a small vessel vasculitis such as A

179 Several assays indicate that Frzb-1 and Crescent modulate primary mouth formation by suppressing

180 ization, solid particles with the shape of a crescent moon are formed; removal of fluorocarbon oil yi

181 erse amphiphilic particles in the shape of a crescent-moon and use these particles to stabilize oil d

182 sedentary agrarian societies in the Fertile Crescent more than 10,000 years ago.

183 , and others the steady gliding motility and crescent morphology of a fish keratocyte.

184 ow showed accelerated disease with increased crescents, necrosis, glomerular monocytes, and renal IL-

185 mission electron microscopy: neither typical crescents nor immature virions were detected in the abse

186 ction in serum cystatin-C levels and reduced crescent numbers compared with WT mice, whereas PodMRKO

187 Although the detached crescents observed upon loss of A30 or G7 echo those see

188 Moreover, iCPCs injected into the cardiac crescent of mouse embryos differentiated into cardiomyoc

189 ency of iCPCs via injection into the cardiac crescent of mouse embryos.

190 m RGCs in the peripheral ventrotemporal (VT) crescent of the retina.

191 apical cortex; yet, they show normal apical crescents of Baz/Par3, Pins, Inscuteable, and Discs larg

192 rrestin-1 levels in podocytes retrieved from crescents of patients with proliferative glomerulopathie

193 Indeed, expanded crescents of the Nup107-160 complex encircled unattached

194 nology of dairying beginning in the 'Fertile Crescent' of the Near East and its spread across Europe.

195 de of the epiblast by 5.75 d.p.c. and form a crescent on the anterior half of the embryo at the onset

196 and found significant linkage to glomerular crescents on chromosome 2 (Crgn8, LOD = 3.8).

197 otein Prickle-like 2 (Pk2) is distributed in crescents on the medial sides of vestibular epithelial c

198 , the viral membrane is first discerned as a crescent or circle lacking obvious continuity with a cel

199 l molecular strands that adopt well-defined, crescent or helical conformations.

200 ssipated such that PSGL-1 was localized in a crescent or ring away from the cell periphery, and F-act

201 Crescent overexpression dorsalized whole embryos but not

202 the presence of a line of polarity reversal, crescent position is not altered between hair cells of o

203 nt findings that the WNT inhibitors Dkk1 and crescent possess cardiac-inducing activities led to the

204 Crescent protein lost its dorsalizing activity in Chordi

205 olding (the molding of membranes through the crescent protein shape) and membrane insertion (also cal

206 ue is damaged by the development of a myopic crescent, rather than simply translocated in a temporal

207 LCrgn1,2) produced markedly fewer glomerular crescents, reduced macrophage infiltration, and decrease

208 e numerous studies, the origin of glomerular crescents remains unresolved.

209 ut not ventral half-embryos, indicating that Crescent requires a dorsal component to exert its anti-B

210 ent results indicate that the characteristic crescent shape of Caulobacter crescentus depends upon an

211 h affinity (K(a) >10(7) M(-1)), and that the crescent shape of coralyne appears necessary for poly(A)

212 binding compounds is that they should have a crescent shape that closely fits the helical twist of th

213 formational changes that allow it to adopt a crescent shape that now complements the minor groove str

214 rgy-minimized state, it adopts a more planar crescent shape when bound in the minor groove of the DNA

215 The holoenzyme adopts an elongated crescent shape with an R(G) of approximately 65.3 A and

216 -loop-helix repeats arranged into an overall crescent shape.

217 Atg17 is crescent shaped with a 10 nm radius of curvature.

218 articular position within the cell body; (2) crescent-shaped "caps" that occupied one pole of the cel

219 t completely denuded of RPE, and there was a crescent-shaped area of photoreceptor degeneration or at

220 dal oculomotor complex were distributed in a crescent-shaped band that lined the ventral and rostral

221 Crescent-shaped BAR domains are generic actors in the cr

222 , such as wedge-like amphipathic helices and crescent-shaped BAR domains, are required for bending me

223 Shallow hydrophobic insertions and crescent-shaped BAR scaffolds promote membrane curvature

224 Polymeric spirals of crescent-shaped BAR-domain superfamily proteins are tout

225 The structure reveals a crescent-shaped base made up of the amino-terminal, midd

226 studies of prokaryotic proteins, revealing a crescent-shaped base made up of the amino-terminal, PAZ,

227 The concave surface of the crescent-shaped Bin-amphiphysin-Rvs (BAR) domain is post

228 his fascinating zigzag-shaped pattern yields crescent-shaped diffraction pattern.

229 bedding in the lipid bilayer and the charged crescent-shaped dimer acting to "scaffold" membrane curv

230 vesiculates lipid membranes in vitro via its crescent-shaped dimer and four amphipathic helices that

231 f PICK1 (PICK1-PDZ) to the homology-modeled, crescent-shaped dimer of the PICK1-BAR domain using mult

232 It is a crescent-shaped dimer that binds preferentially to highl

233 ysin/Rvs (F-BAR) domain family proteins form crescent-shaped dimers, which can bend membranes into bu

234 aorbital nerve afferents displayed a similar crescent-shaped distribution, suggesting they drive thes

235 Their active sites are located in a crescent-shaped groove on the barrel's outer surface, wh

236 FKBP26 is a crescent-shaped homodimer.

237 arrel with a hydrophobic interior supports a crescent-shaped hydrophilic active site on its outer sur

238 filament inclusion disease, and annular and crescent-shaped inclusions were seen in both conditions.

239 I-BAR proteins contain an all-helical, crescent-shaped IRSp53-MIM domain (IMD) dimer that is be

240 (ER) throughout the cell and at the edges of crescent-shaped IV precursors.

241 vaccinia virus begins with the appearance of crescent-shaped membrane precursors of immature virions

242 on of an N-terminal domain homologous to the crescent-shaped membrane-tubulating EFC/F-BAR domains an

243 virus structures except for occasional short crescent-shaped membranes and electron-dense lacy struct

244 Crescent-shaped membranes were continuous with the endop

245 Pus10 is a crescent-shaped molecule with two domains, the universal

246 nce of RNA synthesis, Pat1b redistributes to crescent-shaped nucleolar caps.

247 tructure of the complex reveals an elongated crescent-shaped particle in which two Mdm12 subunits occ

248 ingle particle electron microscopy reveals a crescent-shaped particle that bears striking resemblance

249 tended conformation, Gemin2 wraps around the crescent-shaped pentamer, interacting with all five Sm p

250 biogenesis, before the development of short crescent-shaped precursors of the viral envelope.

251 The VLR genes encode for crescent-shaped proteins that use variable beta-strands

252 ural tube precursors are present in a broad, crescent-shaped region of the gastrula.

253 n addition to forming canonical eight-repeat crescent-shaped RNA-binding domains found in classical P

254 s show that the Zf-GRF fold is typified by a crescent-shaped ssDNA binding claw that is flexibly appe

255 The structure of Csa2 reveals a crescent-shaped structure unexpectedly composed of a mod

256 conserved dimeric module characterized by a crescent-shaped structure whose intrinsic curvature, fle

257 demonstrated the importance of the charged, crescent-shaped surface and the N-terminal amphipathic h

258 II: the ZnF-DNA binding domain (DBD) forms a crescent-shaped surface used for DNA end recognition whi

259 t, with circular receptive-field centers and crescent-shaped surrounds (0.63 degree offset) that had

260 rom Italy, these specimens have a flattened, crescent-shaped ulna with a long axis perpendicular to t

261 step process, starting with the formation of crescent-shaped viral membranes, followed by their enclo

262 cterized by a spherical, acentric core and a crescent-shaped, electron-dense shell lying just inside

263 th a novel linker helix, form an integrated, crescent-shaped, symmetrical dimer.

264 In early stages, this region appears crescent-shaped, while advanced stages show a ring-like

265 ant-based subsistence in the eastern Fertile Crescent (southeast Turkey, Iran, and Iraq) focused on t

266 fields in the geographic area of the Fertile Crescent, spanning the Aceramic Neolithic [10,000 calibr

267 -oscillations (SACOs) in the forming cardiac crescent (stage E7.75) prior to overt beating.

268 Results demonstrated that, at cardiac crescent stages, HCN4 marks the first heart field, with

269 Fabrication provides good control over the crescents' structural properties which enables tuning of

270 Most importantly, we identified novel Gat1p crescent structures that are formed in the presence of o

271 rn Europe; the Middle East and Mediterranean crescent; sub-Saharan Africa; India; China; and southeas

272 at included the external lateral and lateral crescent subdivisions of the lateral PB more than double

273 coordinated between adjacent cells, and the crescents subsequently are lost by E18.5.

274 nduced NCGN (16.7%+/-6.0% versus 2.4%+/-1.7% crescents), suggesting that IL-1beta is a critical infla

275 also required at later stages, when membrane crescents surround virosomal contents and develop into i

276 but pheromone induces its polarization into "crescents" that cap the future mating projection.

277 the accumulation of large virosomes, empty "crescents" that fail to contact these virosomes, and, mo

278 ing the origin of agriculture in the Fertile Crescent, the broad spectrum of wild plant species explo

279 ome patients with membranous nephropathy and crescents, the crescentic lesion may be due to a distinc

280 In cellular crescents, the proliferation marker Ki-67 was expressed

281 pes contributed to the formation of cellular crescents through proliferation in situ.

282 ells correlated with a single or no LGN-NuMA crescent, tilted spindles, and the development of latera

283 ical Partner of Inscuteable (Pins)-G alpha i crescent to divide asymmetrically, but the link between

284 se phenotypes is explained by the ability of Crescent to inhibit Tolloid metalloproteinases, which no

285 METHODS AND The CRESCENT trial (Calcium Imaging and Selective CT Angiogr

286 s, which are generated in the ventrotemporal crescent (VTC) of the retina, specifically express Boc,

287 tinct from Isl2 RGCs in the ventral-temporal crescent (VTC), the source of ipsilateral projections.

288 al RGCs are restricted to the ventrotemporal crescent (VTC).

289 Enzyme kinetic studies showed that Crescent was a competitive inhibitor of Tolloid activity

290 a region resembling the myopic peripapillary crescent was visible in cortical sections processed for

291 The presence and size of optic disc crescents were also investigated as an index of retinal

292 However, crescents were also seen in WKY rats that were given Lew

293 80 +/- 2% of glomeruli at day 10, whereas no crescents were seen in Lewis rats.

294 s, classic wire loop lesions, and occasional crescents were seen only in kidneys from NZM2328.DR3(+)A

295 m the Zagros region of Iran (eastern Fertile Crescent), where some of the earliest evidence for farmi

296 omote formation of a basal Numb and Prospero crescent, which will be asymmetrically segregated to the

297 sors differentiate rapidly to form a cardiac crescent, while limited morphogenesis takes place.

298 tein, the overall shape of which resembles a crescent with a head and a body domain, with a protein f

299 sulting in the formation of typical cellular crescents with periglomerular infiltrate, albeit without

300 mesticated in different parts of the Fertile Crescent, with genetic analyses detecting multiple domes