ライフサイエンスコーパス: crescentic

1 ung contusions tended to be posterior (60%), crescentic (50%), or amorphous (45%) and have confluent

2 ith small flakes, microblades, and retouched crescentic and trapezoidal tools, probably projectile el

3 ar-Kyoto rats with bovine GBM also induced a crescentic anti-GBM GN with an increase of renal cortica

4 ized with rabbit IgG, induced an accelerated crescentic anti-GBM GN.

5 cumulation and renal injury in experimental, crescentic anti-GBM nephritis.

6 Minor terminal fields were identified in a crescentic column of the lateral PAG, as well as in the

7 izumab may have a place in the management of crescentic dense deposit disease.

8 litting margin (stage 1), an inward detached crescentic flap lying on the anterior lens (stage 2), a

9 el to each other rather than in star-like or crescentic forms--are the most abundant type of desert s

10 onstrated to be involved in animal models of crescentic glomerulonephritis (cGN) and are potential ta

11 Crescentic glomerulonephritis (Crgn) is a complex diseas

12 Crescentic glomerulonephritis (Crgn) is a complex disord

13 Crescentic glomerulonephritis (GN) is a devastating dise

14 phages to progressive renal injury in murine crescentic glomerulonephritis (GN).

15 that ANCA cause pauci-immune necrotizing and crescentic glomerulonephritis (NCGN) and systemic small

16 evidence that MPO-ANCA cause necrotizing and crescentic glomerulonephritis (NCGN) and vasculitis.

17 development of pauci-immune necrotizing and crescentic glomerulonephritis (NCGN).

18 o ANCA-associated vasculitis and necrotizing crescentic glomerulonephritis (NCGN).

19 ly progressive glomerulonephritis/idiopathic crescentic glomerulonephritis (RPGN/ICG), IgA nephropath

20 ronounced in females, which developed severe crescentic glomerulonephritis accompanied by heavy prote

21 microscopic polyangiitis or necrotizing and crescentic glomerulonephritis achieve remission with the

22 city of Th17 cells in a mouse model of acute crescentic glomerulonephritis and in a mouse chronic mod

23 dose of 1600 microg/kg induced pauci-immune crescentic glomerulonephritis and lung hemorrhage in all

24 400 microg/kg of myeloperoxidase resulted in crescentic glomerulonephritis and lung hemorrhage in all

25 Crescentic glomerulonephritis and lung hemorrhage were M

26 s model so that all animals reliably develop crescentic glomerulonephritis and lung hemorrhage.

27 f patients with pauci-immune necrotizing and crescentic glomerulonephritis and systemic small vessel

28 both glomerular and interstitial fibrosis in crescentic glomerulonephritis and that neutralization of

29 microscopic polyangiitis and necrotizing and crescentic glomerulonephritis associated with antineutro

30 l, illustrate that TLR4 stimulation triggers crescentic glomerulonephritis by effects on both the ada

31 the role of SPARC in mediating experimental crescentic glomerulonephritis by inducing passive nephro

32 We hypothesized that the MDM2 would drive crescentic glomerulonephritis by NF-kappaB-dependent glo

33 ion is effective in reducing the severity of crescentic glomerulonephritis even when treatment is sta

34 early along the mouse GBM in vivo, eliciting crescentic glomerulonephritis in Fcgr2b(-/-) mice suscep

35 ty of collagen-induced arthritis in mice and crescentic glomerulonephritis in rats, in part by decrea

36 everal susceptibility loci, Crgn1-Crgn7, for crescentic glomerulonephritis in the Wistar Kyoto (WKY)

37 ndance resulting from experimentally induced crescentic glomerulonephritis in these rats.

38 The residual genetic susceptibility to crescentic glomerulonephritis in WKY.LCrgn1,2 rats assoc

39 Crescentic glomerulonephritis is an important cause of h

40 he migration of leukocytes into glomeruli in crescentic glomerulonephritis is fundamental to pathogen

41 Concomitant crescentic glomerulonephritis led to an initial mistaken

42 kidney and lung basement membranes, neither crescentic glomerulonephritis nor alveolitis ensued, lik

43 WKY) rat strain, we have identified multiple crescentic glomerulonephritis QTL (Crgn) and positionall

44 plenocytes into immune-deficient mice caused crescentic glomerulonephritis that could be completely b

45 In these mice, crescentic glomerulonephritis was induced with a previou

46 control IgG developed focal necrotizing and crescentic glomerulonephritis with a paucity of glomerul

47 CR1 also promoted influx of DC precursors in crescentic glomerulonephritis, a DC-dependent aggressive

48 apsing glomerulopathy variant), pauci-immune crescentic glomerulonephritis, acute interstitial nephri

49 atment experiment, all rats developed florid crescentic glomerulonephritis, and control rats showed m

50 li were also noted in amyloidosis, diabetes, crescentic glomerulonephritis, and diffuse endocapillary

51 ome, idiopathic pauci-immune necrotizing and crescentic glomerulonephritis, and related and overlappi

52 With the emergence of necrotizing/crescentic glomerulonephritis, approximately 0.15% of re

53 splenocytes developed severe necrotizing and crescentic glomerulonephritis, granulomatous inflammatio

54 Excluding pauci-immune necrotizing and crescentic glomerulonephritis, IgG4 immunohistochemistry

55 Moreover, in patients with crescentic glomerulonephritis, IL-26 is expressed by ren

56 ANCA-positive patients with necrotizing and crescentic glomerulonephritis, including 69 with evidenc

57 e's syndrome (GPS) develop severe autoimmune crescentic glomerulonephritis, kidney failure, and lung

58 or and found increased life span, suppressed crescentic glomerulonephritis, reduced spleen size, and

59 ng the kidneys, where they cause necrotizing crescentic glomerulonephritis.

60 (PEC) are major constituents of crescents in crescentic glomerulonephritis.

61 oto (WKY) rat shows marked susceptibility to crescentic glomerulonephritis.

62 of renal injury in an experimental model of crescentic glomerulonephritis.

63 s approach is effective in the prevention of crescentic glomerulonephritis.

64 proaches may be worth investigating in human crescentic glomerulonephritis.

65 amined the effect of an antibody to VLA-1 in crescentic glomerulonephritis.

66 e as the pre-emptive treatment in abrogating crescentic glomerulonephritis.

67 kade by nutlin-3a ameliorated all aspects of crescentic glomerulonephritis.

68 izations were needed to induce a necrotizing/crescentic glomerulonephritis.

69 autoimmune glomerulonephritis or necrotizing/crescentic glomerulonephritis.

70 corticoids, renal function in a rat model of crescentic glomerulonephritis.

71 sion of crescentic lesions in a patient with crescentic glomerulonephritis.

72 iquely susceptible to experimentally induced crescentic glomerulonephritis.

73 elerating glomerulosclerosis in experimental crescentic glomerulonephritis.

74 murine anti-MPO Abs derived from Spontaneous Crescentic Glomerulonephritis/Kinjoh mice.

75 h1 cells are central pathogenic mediators of crescentic GN (cGN).

76 Cs belong to the CD11b(+) subset and promote crescentic GN (cGN).

77 t endothelial NF-kappaB mediates necrotizing crescentic GN (NCGN) and provides a specific treatment t

78 asmic antibody (ANCA)-associated necrotizing crescentic GN (NCGN) is incompletely understood.

79 Necrotizing and crescentic GN (NCGN) with a paucity of glomerular immuno

80 phagocytes cause vasculitis and necrotizing crescentic GN (NCGN).

81 Here, using a mouse model of acute crescentic GN (nephrotoxic nephritis), we identified CD4

82 sociated crescentic GN and a murine model of crescentic GN (nephrotoxic nephritis).

83 etic nephropathy, 19; immune complex GN, 12; crescentic GN (vasculitis), 6; hemolytic uremic syndrome

84 DBA/1 mice had crescentic GN 11 wk postimmunization with alpha3(IV)NC1.

85 the kidneys of patients with ANCA-associated crescentic GN and a murine model of crescentic GN (nephr

86 the kidneys of patients with ANCA-associated crescentic GN and colocalize with CXCR3(+) effector T ce

87 Furthermore, biTregs appear to contribute to crescentic GN and hence may be novel therapeutic targets

88 e response and tissue injury in experimental crescentic GN and show that miR-155 is a potential thera

89 hlight the suppressive functions of Tregs in crescentic GN and suggest the importance of Treg-derived

90 ls, which have been shown to protect against crescentic GN and which require IKK2.

91 the kidneys of patients with ANCA-associated crescentic GN as opposed to patients with acute bacteria

92 membrane (GBM) antibody (Ab) GN, a model of crescentic GN in the WKY rat, and whether the effects of

93 NFkappaB-inducing kinase IKK2 can attenuate crescentic GN, a severe DC- and Th cell-dependent kidney

94 are key effectors of disease progression in crescentic GN, acting to regulate parenchymal cell popul

95 hrombotic microangiopathies, necrotizing and crescentic GN, acute tubular necrosis, and infective pye

96 evidenced by the development of necrotizing crescentic GN, albuminuria, renal impairment, and accumu

97 ically target Th17 cells in murine and human crescentic GN, and suggest the kidney-specific action of

98 o the pathogenesis of human and experimental crescentic GN, but the cell types that produce IL-17A in

99 c cells (DCs) are protective early in murine crescentic GN, but the mechanisms underlying this protec

100 antineutrophil cytoplasmic antibody-mediated crescentic GN, lupus nephritis, type I membranoprolifera

101 In murine crescentic GN, Mif-deficient mice were almost completely

102 udies suggest a role for Tregs in modulating crescentic GN, the underlying mechanisms are not well un

103 Using a murine model of crescentic GN, we explored the effects of the CCL18 muri

104 Here, using a murine model of crescentic GN, we found that CD4(+) T cells, gammadelta

105 Using a murine model of crescentic GN, we show that the pathogenic TH17/IL-17 im

106 nephritis (GN) as well as from patients with crescentic GN, with the aim of identifying potential ren

107 phages through days 15 and 20 of progressive crescentic GN.

108 ferative, acute proliferative/exudative, and crescentic GN.

109 re) x Cxcr3(fl/fl)) and induced experimental crescentic GN.

110 r of diseases such as human and experimental crescentic GN.

111 d IL-17F drives renal tissue injury in acute crescentic GN.

112 e nephrotoxic nephritis (NTN) model of acute crescentic GN.

113 e nephrotoxic nephritis (NTN) model of acute crescentic GN.

114 hose in sera of patients with other forms of crescentic GN.

115 ctivity and renal relapse in ANCA-associated crescentic GN.

116 ted vasculitis is the most frequent cause of crescentic GN.

117 y samples from patients with ANCA-associated crescentic GN.

118 atients with newly diagnosed ANCA-associated crescentic GN.

119 observed in biopsy samples of patients with crescentic GN.

120 in the nephrotoxic nephritis (NTN) model of crescentic GN.

121 ne disease, including human and experimental crescentic GN.

122 econdary lymphoid tissue in a mouse model of crescentic GN.

123 nd contributing to the immunopathogenesis of crescentic GN.

124 he kidney in the early stage of experimental crescentic GN.

125 t microscopy demonstrated pale pink, oval to crescentic intracytoplasmic inclusions with a predilecti

126 th membranous nephropathy and crescents, the crescentic lesion may be due to a distinct, separate dis

127 and molecular interactions occurring during crescentic lesion onset and evolution.

128 n progenitors concomitant with regression of crescentic lesions in a patient with crescentic glomerul

129 re 91% for focal, 69% for mixed, and 64% for crescentic (log-rank P<0.0001).

130 e Internet after a renal biopsy demonstrated crescentic, necrotizing glomerulonephritis and linear de

131 ice treated with nephrotoxic serum to induce crescentic nephritis (rapidly progressive GN), this gene

132 munity, was necessary for the development of crescentic nephritis in this model.

133 ation and the progression to fibrosis during crescentic nephritis we have developed and characterized

134 marked reduction in albuminuria, severity of crescentic nephritis, and number of glomerular macrophag

135 e identified a novel therapeutic approach in crescentic nephritis, that of glucocorticoid antagonism,

136 B- and T-cell epitopes in EAG and can induce crescentic nephritis.

137 important role in the inflammatory phase of crescentic nephritis.

138 ated glomerular parietal epithelial cells in crescentic nephritis.

139 Patients classified as crescentic or mixed, however, had worse survival when th

140 e classified as absent, pinpoint, flattened, crescentic, or ellipsoidal flow.

141 categorizes patients as having focal, mixed, crescentic, or sclerotic GN.

142 study of modern cryptochirid domicile shape (crescentic pit, circular-oval pit, or a true gall) shows

143 Crescentic pits in corals occur not only in the Western

144 ridae fam. nov. Nine Pleistocene corals with crescentic pits originate from Florida (USA), and single

145 tochirids in the fossil record through their crescentic pits, typical for certain cryptochirids, in W

146 Crescentic rapidly progressive glomerulonephritis (RPGN)

147 In crescentic RPGN the role of cellular rather than humoral

148 ion in 22 patients (75.9%) with a pattern of crescentic thickening in 19 (86.4%).

149 ent's slowly progressive GN underwent severe crescentic transformation, leading to rapidly progressiv