ライフサイエンスコーパス: critical concentration

1 entrating a sample about the poly(A)-ligand 'critical concentration'.

2 tration of the globular aggregates exceeds a critical concentration.

3 n in filamentous mass and an increase in tau critical concentration.

4 e and MJD patients that is cytotoxic above a critical concentration.

5 fected neuroblastoma cells was toxic above a critical concentration.

6 no effect on pointed-end kinetics or on the critical concentration.

7 se of R177H actin but slightly decreases its critical concentration.

8 d causes cell death if it accumulates past a critical concentration.

9 evidence of a nucleation phase and without a critical concentration.

10 e ends that determine the value of the actin critical concentration.

11 f the ends by tropomodulin did not alter the critical concentration.

12 ation slowed, but there is also an effect on critical concentration.

13 on at lower concentrations without a defined critical concentration.

14 actin monomers with some deviations near the critical concentration.

15 cin (CAP) using MGIT 960 and WHO-recommended critical concentrations.

16 ms of alpha-synuclein do not differ in their critical concentrations.

17 The critical concentrations above which aggregation begins c

18 mutant actin exhibited a higher than normal critical concentration and a delayed nucleation.

19 The dependences of the steady-state critical concentration and average filament length of ac

20 phage lysis occurs when the holin reaches a critical concentration and nucleates to form rafts, anal

21 In agreement, Ca(2+) decreases SOD1 critical concentration and nucleation time during aggreg

22 R177H actin has an increased critical concentration and polymerizes with a greatly ex

23 is, the soft nanoactahedra crystallize at a critical concentration and possess continuous crystallin

24 leation phenomena; we obtained lower tubulin critical concentrations and shorter polymers with discod

25 ity to inactivate DNase I, increases actin's critical concentration, and greatly reduces its rate of

26 SipA binds directly to actin, decreases its critical concentration, and inhibits depolymerization of

27 established from filament dissociation rate, critical concentration, and mass-per-unit length measure

28 apid mixing when thrombin was added near the critical concentration, and mixing also affected the rat

29 tranded filaments and larger bundles above a critical concentration, and they hydrolyze GTP at a very

30 Vinblastine-induced polymerization shows a critical concentration, and, in the presence of GTP, two

31 arbed end growth of filaments and lowers the critical concentration at the bacterial surface.

32 We show that growth rates and the critical concentration at the barbed end are intimately

33 s about the origins of the difference in the critical concentration at the two ends of actin filament

34 Critical concentrations at which the inner leaflet is di

35 centrations at least 10-fold below the usual critical concentration, at the expense of increased cata

36 the neutrophil concentration approaches the critical concentration, bacterial populations in contact

37 , the simulations predict the existence of a critical concentration below which tH does not form nano

38 there is no evidence for assembly below the critical concentration, but there is an abrupt transitio

39 ells binds actin filaments and decreases the critical concentration (C(c)) for actin polymerization.

40 lizes the filament lattice and increases the critical concentration (C(c)) for assembly.

41 l to FtsZ concentration from 0.7 microm (the critical concentration (C(c))) to 3 microm.

42 The much higher values of the critical concentrations, C(a)*, for the disappearance of

43 n, and, in the presence of GTP, two distinct critical concentrations can be identified.

44 asurements of high length diffusivity at the critical concentration cannot be explained by fragmentat

45 previously unreported temperature-dependent critical concentration (Cc) that resembles a solubility

46 s of equilibrium constants produce the sharp critical concentrations characteristic of cooperative po

47 ith a lag phase shorter than ATP-actin and a critical concentration close to zero.

48 degree, laminin-4, even well below their own critical concentration, co-aggregated with laminin-1, ev

49 Third, for HC-1, the antibody at a critical concentration completely suppressed viral repli

50 As expected for semirigid chains, the critical concentrations decrease sharply with increasing

51 e polymerization rate increases and the bulk critical concentration decreases with increasing tempera

52 However, the critical concentration did increase when the tropomoduli

53 For side branching, the critical concentration drops proportionally to the squar

54 drops with increasing branching, because the critical concentration drops.

55 pesticide inputs, leading to environmentally critical concentrations during rain events.

56 The critical concentration established for levofloxacin and

57 isolates for 48 h with and without drugs at critical concentrations, followed by incubation with 10(

58 s at nanomolar concentration, well below the critical concentration for Abeta fibril formation in the

59 concentrations both below and above c*, the critical concentration for Abeta micelle formation.

60 Fesselin did not alter the critical concentration for actin but did increase the ra

61 n initiating amyloidogenesis by lowering the critical concentration for aggregation into the nanomola

62 olymerization defects, with a 40-fold higher critical concentration for assembly than WT SM alpha-act

63 vating the coat and effectively lowering its critical concentration for assembly.

64 minus ends, movement by treadmilling, and a critical concentration for assembly.

65 The measurements show that the lower critical concentration for cobalt hexammine as compared

66 FtsZ has to be at or above the critical concentration for copolymerization to occur, in

67 entration many orders of magnitude below the critical concentration for fibrillation in the bulk solu

68 * did not affect FtsZ GTPase activity or the critical concentration for FtsZ assembly but was able to

69 tion resulted in an increase in the apparent critical concentration for FtsZ assembly.

70 cooperative self-assembly model to obtain a critical concentration for lattice assembly.

71 Below the critical concentration for microtubule assembly and in t

72 microtubule nucleation, reduces the tubulin critical concentration for microtubule assembly, and sup

73 le growth constant, equal to Cr-1 (Cr is the critical concentration for microtubule formation), and K

74 formation and found that the drug raises the critical concentration for microtubule polymerization in

75 ntrinsic to the tubulin dimer and reduce its critical concentration for polymerization at 0 degrees C

76 pparent nanomolar affinity and increases the critical concentration for polymerization at the pointed

77 The critical concentration for polymerization obtained by th

78 sheets in the presence of calcium, and has a critical concentration for polymerization of 1.5 muM.

79 Saturating phosphate reduces the critical concentration for polymerization of Mg-ADP-acti

80 te of nucleotide exchange was increased, the critical concentration for polymerization was increased,

81 rties of pY53-actin, including its increased critical concentration for polymerization, reduced rates

82 cant fraction (~10%) of stable dimers at the critical concentration for polymerization, supporting a

83 ribution (Kd = 1.2 microM) and increases the critical concentration for polymerization.

84 ing a large pool of actin monomers above the critical concentration for polymerization.

85 and this boundary is always larger than the critical concentration for the actin filament's growth a

86 hout Mg(2+), by significantly increasing the critical concentrations for assembly.

87 Further studies are needed to evaluate critical concentrations for ethambutol and streptomycin

88 ce as stiff as DNA, primarily because of low critical concentrations for first appearance of the anis

89 This review provides support for recommended critical concentrations for isoniazid and rifampin in co

90 Critical concentrations for the isotropic to cholesteric

91 up to twofold while slightly decreasing the critical concentration from 0.23 microM to 0.18 microM.

92 To explain the effect of profilin on actin critical concentration in a manner consistent with therm

93 ound in cells, and the effect of profilin on critical concentration in cell extracts is demonstrated

94 perativity observed in FtsZ kinetics and the critical concentration in different buffer media.

95 nism also predicts the effect of profilin on critical concentration in the presence of the limited am

96 in was added at concentrations far above the critical concentration in two clinical clotting assays f

97 perative self-assembly model that exhibits a critical concentration in vivo.

98 olchicine site ligand, and measuring tubulin critical concentrations in the presence of poorly solubl

99 t mass correlated strongly with decreases in critical concentration, indicating that both pseudophosp

100 ncreased nucleation rates, and submicromolar critical concentrations, indicating a final equilibrium

101 produce new nucleation sites, and the upper critical concentration is determined by the supersaturat

102 When a critical concentration is reached, the alignment of nano

103 2+) (which allows FtsZ to hydrolyze GTP) the critical concentration is reduced 10-fold to approximate

104 At this critical concentration, it is calculated that a minimum

105 ersus actin concentration yields an apparent critical concentration, like that seen for actin polymer

106 Critical concentration measurements confirmed that N744

107 Here, we theoretically derive the critical concentration nc for films of heavily doped nan

108 pH via a nucleation-growth mechanism, with a critical concentration near 1 mM.

109 ctin in T. gondii lacks both a lag phase and critical concentration, normally characteristic of actin

110 onic acid at the sn-2 position occurs when a critical concentration of 'seeding molecules' derived fr

111 (e.g., self-assembles to form micelles at a critical concentration of 0.1 mM in aqueous 0.1 M Li(2)S

112 A critical concentration of 0.4-1.0 microM was indicated b

113 the "aggregated" state begins to occur at a critical concentration of 1 AmB per 1000 lipids in the m

114 GTP-actin polymerizes with an apparent critical concentration of 1.5 microm, higher than that o

115 A critical concentration of 900 or 1,200 microg of PZA/ml

116 iviral activity of A3G in vivo may require a critical concentration of A3G in viral particles that wi

117 A critical concentration of about 0.8 microg/mL of 1 is fo

118 even at concentrations much higher than the critical concentration of actin filaments, indicating th

119 if molecular crowding results in a very low critical concentration of actin in vivo.

120 In the presence of TPM, the apparent critical concentration of actin is 5.5 microm, 10-15-fol

121 amount of sequestered actin (by lowering the critical concentration of actin) and augments nucleation

122 vitro that TPM can significantly affect the critical concentration of actin.

123 eady state, F-actin depolymerizes toward the critical concentration of ADP-actin, our analysis indica

124 Our results show that once a small but critical concentration of amyloid fibrils has accumulate

125 We have used this equation to calculate the critical concentration of antigen-specific CD8+ T cells,

126 orylated cofilin, we estimate a mean G-actin critical concentration of approximately 0.45 microM and

127 ivity increases with concentration below the critical concentration of approximately 1 mg/ml for micr

128 similar to that of F-actin, however, with a critical concentration of approximately 3 nm, which is a

129 A22 increases the critical concentration of ATP-bound MreB assembly from 5

130 capping protein, tropomodulin, increases the critical concentration of barbed end capped actin, i.e.

131 Our model predicts a critical concentration of cardiolipin below which domain

132 In bulk semiconductors, the critical concentration of electrons at the metal-insulat

133 For all polymerization processes, a critical concentration of free monomers, as defined by t

134 omplex, similar in magnitude to the 0.72 muM critical concentration of FtsZ protofilament assembly at

135 Moreover, the critical concentration of FtsZ required for ring formati

136 SipA lowers the critical concentration of G-actin, stabilizes F-actin at

137 olymerization was evaluated by measuring the critical concentration of GDP-tubulin in the presence of

138 ignificant extent, but it also decreases the critical concentration of gelator needed to form stable

139 ences associated with measured values of the critical concentration of incubation solution.

140 l prior observation that profilin lowers the critical concentration of Mg2+-actin.

141 lent molecules (gel phase) are produced at a critical concentration of monomers.

142 Below a critical concentration of neutrophils, bacteria growth w

143 nding required both liposome formation and a critical concentration of phospholipid containing phosph

144 l nociceptive response thresholds requires a critical concentration of PLCbeta1 protein, its particip

145 Cbeta1 to thermal pain thresholds requires a critical concentration of PLCbeta1 protein.

146 K113E actin exhibits a critical concentration of polymerization 4 times higher

147 ect was observed on FtsZ GTPase activity and critical concentration of polymerization.

148 ed, and there is a 3-4 fold reduction in the critical concentration of polymerization.

149 heterodimers--spontaneously assemble above a critical concentration of tetravalent spermine and are s

150 ion, HDL containing apoA-I, or at least some critical concentration of the antiatherogenic lipoprotei

151 At the critical concentration of the barbed end, c(crit), we fi

152 A critical concentration of the beta subunit may be requir

153 fore virion production, perhaps lowering the critical concentration of the chimeric protein required

154 rnal scaffolding protein may be to lower the critical concentration of the external scaffolding prote

155 spectroscopy to quantify , which is also the critical concentration of the isotropic-nematic transiti

156 We find that the critical concentration of the isotropic-nematic transiti

157 on in spindle architecture was observed at a critical concentration of the Kinesin-5 sliding motor.

158 of human blood plasma required addition of a critical concentration of thrombin.

159 bulin in the presence of TMAO and lowers the critical concentration of tubulin needed for assembly.

160 Cryptophycin did not alter the critical concentration of tubulin required for polymeriz

161 d A549 lung epithelial cells were exposed to critical concentrations of 0.1 and 0.5 ppm for 3 days.

162 on propagation and neurotoxicity relating to critical concentrations of alternate PrP isoforms whose

163 We propose that the accumulation of critical concentrations of lipid peroxidation adducts du

164 Further studies to develop critical concentrations of other drugs for this low-pH m

165 Critical concentrations of phosphates that could inhibit

166 ts monomer-to-polymer assembly reaction, the critical concentrations of that reaction, the manner in

167 uantitative differences were measured in the critical concentrations of the complexes required for as

168 and assembly but fails to reduce the tubulin critical concentration or suppress dynamic instability;

169 At critical concentration or temperature, the bandgap colla

170 Allele-specific effects were also seen on critical concentration, rate of depolymerization, and fi

171 ration (1.9 vs. 1.4 mg/L), and critical dose/critical concentration ratio (0.52 vs. 2.2).

172 population density, and when this reaches a critical concentration, reflecting a bacterial quorum, s

173 n situ than in the wild type and has a lower critical concentration, reflecting altered nucleation pr

174 decrease in the probability of reaching the critical concentration required for a nucleation event a

175 Critical concentration required for deoxy Hb S beta87 Th

176 At concentrations of drug lower than the critical concentration required for Raf-1 activation, p5

177 yloidogenic polypeptide in vivo is below the critical concentration required to form the aggregates o

178 pparently cooperative process, with a higher critical concentration than values reported for other Ft

179 enzyme-catalyzed lipid hydrolysis reaching a critical concentration that allows the enzyme to react a

180 CT1) rapidly polymerized into filaments at a critical concentration that was 3-4-fold lower than conv

181 further show that polymerization requires a critical concentration that we propose is only achieved

182 Interestingly, above a critical concentration, the addition of palmitic, steari

183 he initial stage; once the oligomers reach a critical concentration, the blackberry formation process

184 sorb onto the lipid membranes, and then at a critical concentration, the peptides begin to aggregate

185 -dependent conductivity on both sides of the critical concentration, thus establishing the quantum-cr

186 the master regulator Spo0A, which rises to a critical concentration to initiate sporulation.

187 P(i)-actin (low critical concentration) to ADP-actin (high critical conc

188 moderate differences between the ATP and ADP critical concentrations, treadmilling may occur, but we

189 ibril elongation thermodynamics derived from critical concentration values for fibril growth.

190 Critical concentration values of wild-type and mutant pr

191 The increase in apparent critical concentration was always less than the total am

192 ster than wild-type (WT) actin, although the critical concentration was not affected.

193 mers' interaction with the bilayer below the critical concentrations was also found.

194 ce of interaction with the bilayer below the critical concentrations was observed for the 11Bz polyme

195 Three critical concentrations were determined; stimulation sta

196 ns in system recovery, and the corresponding critical concentrations were generally between 5 and 15

197 rent insulator compound is doped beyond some critical concentration; what exactly happens at this sup

198 y forms monodisperse nanotubes (NTs) above a critical concentration when solubilized in pure water.

199 w critical concentration) to ADP-actin (high critical concentration) when 70-98% of the ends are capp

200 ible reactions are characterized by a pseudo-critical concentration, whereas irreversible reactions c

201 FtsZ-GTP without Mg(2+) exhibits an apparent critical concentration, which is indicative of cooperati

202 titatively assessed through determination of critical concentrations, which can be used to obtain the

203 rt, from an apparent lowering of the tubulin critical concentration with drug combinations compared w