ライフサイエンスコーパス: critical role

1 Epigenetic mechanisms play a critical role during differentiation of T cells by contributi

2 Here we identify a critical role for ETAA1 in this process by surveying random g

3 ofiling and genetic loss-of-function experiments revealed a critical role for FOXO transcription factors in mediating the

4 These results demonstrate a critical role for genetic variation in ChrY in regulating sus

5 Our data suggest a critical role for nonclassical monocytes in the pathology of

6 Our data demonstrate a critical role for perisomatic inhibition mediated by PV-conta

7 rization of longer polySia chains on SynCAM 1, suggesting a critical role for polyST autopolysialylation in substrate sel

8 Together, our study implicates a critical role for Set1A catalytic methyltransferase activity

9 pport that delta-secretase phosphorylation by SRPK2 plays a critical role in aggravating AD pathogenesis.

10 NM myosin II plays a critical role in airway SM contraction that is independent an

11 Bioinformatics and computational biology play a critical role in bioscience and biomedical research.

12 bolic regulator AMP-activated protein kinase (AMPK) plays a critical role in blocking modifications to the chromatin land

13 Reactive oxygen species (ROS) play a critical role in cell signaling and proliferation.

14 The mitochondria-associated ER membrane (MAM) plays a critical role in cellular energetics and calcium homeostasis;

15 Epigenetic regulation of chromatin plays a critical role in controlling embryonic stem (ES) cell self-re

16 kinase activity.IMPORTANCE The antiviral kinase PKR plays a critical role in controlling HCMV replication.

17 est that wave motions of the tectorial membrane (TM) play a critical role in determining the frequency selectivity of hea

18 Cytokines play a critical role in directing the discrete and gradual transcrip

19 Ebola viral protein 30 (eVP30) plays a critical role in EBOV transcription initiation at the nucleop

20 The forkhead box transcription factor FOXC1 plays a critical role in embryogenesis and the development of many or

21 ion to its function in caveolae biogenesis, Cavin-2 plays a critical role in endothelial cell maintenance and function by

22 Thus, despite their size, small-bodied bees play a critical role in facilitating long-distance pollen-mediated g

23 Hepatitis B virus (HBV)-encoded X protein (HBx) plays a critical role in HBV-related hepatocarcinoma development.

24 re Leishmania is encountered, suggests that they may play a critical role in immune responses to Leishmania.

25 Here, we show that BMP signaling plays a critical role in looping morphogenesis of the avian small int

26 Therefore, we suggest that SHANK3 has a critical role in neuronal morphogenesis in placodal neurons a

27 presents the first direct evidence that Kir channels play a critical role in physiological endothelial responses to flow.

28 Together our findings indicate that PBF and PTTG have a critical role in promoting thyroid cancer that is predictive

29 electron transporting materials (ETMs) used in PSCs play a critical role in PSCs performance.

30 t the GP1 subunit of the Lassa glycoprotein complex plays a critical role in receptor recognition.

31 esults show that WASp is a novel substrate of ALK and has a critical role in regulating invasiveness and oncogenesis of A

32 MPORTANCE Recently, it has been reported that GSDMD plays a critical role in regulating lipopolysaccharide and NLRP3-medi

33 e have identified a novel cellular signaling network with a critical role in regulating the replication of multiple virus

34 rentially abundant features (e.g. species or genes) plays a critical role in revealing the contributors (i.e. pathogens)

35 Cytochrome P450 (P450, CYP) 17A1 plays a critical role in steroid metabolism, catalyzing both the 17al

36 The critical role in surface reactions and heterogeneous catalysi

37 nuclear factor (erythroid-derived 2)-like 2 (NRF2) plays a critical role in the cellular antioxidant response under oxid

38 Venom peptide toxins such as conotoxins play a critical role in the characterization of nicotinic acetylchol

39 s regulate p53beta in a synergistic manner, and NMD plays a critical role in the determination of the p53beta following i

40 es containing Yxxphi motif, but not dileucine motif, play a critical role in the earliest stages of AP2 activation and CC

41 unication, with prominent theories arguing that it played a critical role in the evolution of vocal communication, in bot

42 eavy chain (SMMHC; encoded by CBFB-MYH11) and RUNX1 plays a critical role in the pathogenesis of this leukemia.

43 nsing may have broad biological significance because of the critical role of folate in normal cell function and the wide

44 ys that govern the induction of TH2 differentiation and the critical role of GATA-3 in this process.

45 Accumulating evidence suggests the critical role of mGluR2/3 in different aspects of nicotine ad

46 Collectively, these results reveal a critical role of miR-122 in acetaminophen detoxification and

47 These results confirm the critical role of parrotfish in maintaining coral-dominated re

48 We also demonstrated a critical role of the p53-CXCR2 axis in mediating RSV-induced

49 The critical role of two-phase hydrodynamic properties on non-Fic

50 Our results also highlight the critical role played by antigen density in regulating CAR fun