ライフサイエンスコーパス: critically

1 Overconsumption of high-fat diets (HFDs) can critically affect synaptic and cognitive functions withi

2 s.The competition between chemical reactions critically affects our natural environment and the synth

3 This review critically analyses advances of multivariable sensors ba

4 n addition to electrode variability, to more critically analyze the time course of pharmacological da

5 This paper reviews and critically analyzes the latest developments in the mathe

6 f nucleic acid ion counting measurements and critically analyzes their ability to test both analytica

7 n this review, we examine the impact of AHSV critically and discuss entomological studies that have b

8 In this review, we critically and systematically evaluate available data ex

9 ocessing-suggesting that similar changes may critically, and more broadly, underlie the neural comput

10 To identify, critically appraise and synthesise primary research expl

11 Herein, the authors critically appraise the current state of data and offer

12 Studies were independently screened and critically appraised using established instruments.

13 The aim of this review is to critically assess both possibilities, given that increas

14 ndations, we undertook systematic reviews to critically assess evidence on the effectiveness, safety

15 This is needed to critically assess whether plasma technology can be succe

16 on is to provide a comprehensive review that critically assesses recent advances in the field and hig

17 of the over cut-off emission is found to be critically associated with, and well explained in terms

18 Critically, at P12, inactivation of the medial septum el

19 Critically, both modular segregation and network efficie

20 Critically, both within-subject self-report measures of

21 In this Review, I critically compare the characteristics of the different

22 al ventromedial medulla (RVM) are thought to critically contribute to this process; however, the neur

23 ite located near the beta8-beta9 loop, which critically contributes to coupling ligand binding to cha

24 uman inositol phosphate multikinase (HsIPMK) critically contributes to intracellular signaling throug

25 'cardiac sympathetic afferent reflex' (CSAR) critically contributes to the exaggerated global sympath

26 ed in the alternative possibility that HAART critically contributes to the neuroinflammation in the c

27 larization (CNV), an angiogenic process that critically contributes to vision loss in age-related mac

28 eagenesis, and thereby amino acid levels, is critically controlled by glucagon.

29 sults suggested that Ser-357 phosphorylation critically controls the ligand-independent endocytosis o

30 1-CLL cells express CD1d and that iNKT cells critically delay disease onset but become functionally i

31 Olfactory perception and behaviors critically depend on the ability to identify an odor acr

32 Manufacturing these devices will critically depend on the compatibility of MOFs with exis

33 ance induction after lung transplantation is critically dependent on central memory CD8(+) T lymphocy

34 However, such advances are critically dependent on fundamental systematic research,

35 tion, maturation and stabilisation which are critically dependent on interactions between key pluripo

36 mphocyte transendothelial migration (TEM) is critically dependent on intraendothelial signaling trigg

37 alicylate and the thienopyridone A-769662 is critically dependent on phosphorylation of Ser108 in the

38 f functional spine synapses is thought to be critically dependent on presynaptic glutamatergic signal

39 This fibrillation is critically dependent on properties of the protein and th

40 y, elimination of cancer cells by T cells is critically dependent on the optimal activity of innate i

41 Augmentation was critically dependent on the timing and position of spina

42 in promoting lung metastasis is shown to be critically dependent on the transcription factor Ets2 an

43 hage polarization into M1 and M2 subsets was critically dependent on tumor necrosis factor receptor-a

44 KEY POINTS: Heart function is critically dependent upon the balance of energy producti

45 Here, we show that this updating process critically depends on an ongoing mapping between the rep

46 Transition of PMN rolling to firm adhesion critically depends on Coro1A by regulating the accumulat

47 clear neutrophils (PMNs) during inflammation critically depends on the beta2 integrins lymphocyte fun

48 Telomere maintenance critically depends on the distinct activities of telomer

49 l analysis shows that initiation of motility critically depends on three dimensionless parameter comb

50 Critically, depletion of LARP1 alone in human adult CD34

51 ional states and their interconversion rates critically determine protein function and regulation.

52 nsmembrane AMPAR regulatory proteins (TARPs) critically determine the functional properties of AMPARs

53 ur results showed that interactional context critically determines language control networks' engagem

54 Our results demonstrate that MAFB critically determines the acquisition of the anti-inflam

55 Critically, diminished sensory processing at short RSIs,

56 Here we critically discuss pitfalls and challenges of IG/TR NGS

57 outes of production of these radiometals are critically discussed, as are examples of their applicati

58 ng successes of this enabling technology are critically discussed, highlighting new opportunities, pr

59 iples and fundamentals of flow chemistry and critically discusses recent flow chemistry accounts.

60 The present review critically discusses the latest developments in the fiel

61 athological elevation of Ephexin5 expression critically drives Abeta-induced memory impairment, and s

62 Critically, effective connectivity analysis confirmed th

63 ting field and interview survey data for the critically endangered Bornean orangutan (Pongo pygmaeus)

64 ropean amphibian (8 km(2)) and is considered critically endangered by the International Union for Con

65 The critically endangered mountain gorilla population was su

66 potential conservation implications in this critically endangered species.

67 s for the conservation and management of the critically endangered wild species, Camelus ferus.

68 lation structure and recent evolution of the critically endangered Yangtze finless porpoise (Neophoca

69 Even though the greater bamboo lemur is critically endangered, paleontological evidence shows th

70 The critically endangered, Southern Resident killer whale po

71 n of experimental and theoretical studies to critically evaluate the ability of these rate theories,

72 We also critically evaluate the evidence across 13 meta-analyses

73 In this review, we critically evaluate the evidence across 314 meta-analyse

74 Here we critically evaluate three MOA classification methodologi

75 total phenolic content (TPC) in juices were critically evaluated in terms of their selectivity.

76 This review critically evaluates the crosstalk between the three hor

77 Our review also critically examines the epidemiological data on clinical

78 RV recovered back to 5 when the membrane was critically fouled, and the achieved LRV remained stable

79 ort-term synaptic plasticity-parameters that critically govern neural circuit information processing-

80 effectively conduct numerical evaluations is critically hindered when dealing with large models.

81 nitions of irreversible tissue damage and of critically hypoperfused but potentially salvageable tiss

82 Frailty is common in critically ill adults aged 18 years and older and is ind

83 IONALE: The optimal nutritional strategy for critically ill adults at high nutritional risk is unclea

84 n of systemic candidiasis in immunocompetent critically ill adults did not reduce mortality and may h

85 el has not been shown to improve outcomes in critically ill adults or children after cardiac surgery.

86 Critically ill adults requiring continuous renal replace

87 Forty critically ill adults with fever (core temperature, >/=

88 essenger RNAs, was developed to discriminate critically ill adults with infection-positive versus inf

89 rol (placebo, no protocol, or usual care) in critically ill adults.

90 jury is associated with delirium and coma in critically ill adults.

91 osocomial infections, particularly affecting critically ill and immunocompromised patients.

92 cant interaction among NUTrition Risk in the Critically Ill category, mortality, and protein and ener

93 cant interaction among NUTrition Risk in the Critically Ill category, time to discharge alive, and pr

94 Delirium occurs frequently in critically ill children and is independently associated

95 diatric version of the SOFA score (pSOFA) in critically ill children and to evaluate the Sepsis-3 def

96 s collected from central venous catheters in critically ill children and to examine the effect of the

97 tcomes, including increased mortality, among critically ill children and young adults.

98 actors for iatrogenic withdrawal syndrome in critically ill children.

99 The high mortality rate in critically ill elderly patients has led to questioning o

100 commendation for systematic ICU admission in critically ill elderly patients reduces 6-month mortalit

101 the idea of noninfectious sepsis given that critically ill humans never exist in a germ-free state.

102 ield and use of clinical exome sequencing in critically ill infants.

103 278) were taken from a prospective study of critically ill intensive care unit (ICU) patients meetin

104 semi-structured interviews with chronically critically ill long-term acute care hospital patients or

105 Immunoneutralizing glucagon in critically ill mice only transiently affected glucose an

106 In critically ill mice, infusion of amino acids increased g

107 Atelectasis develops in critically ill obese patients when undergoing mechanical

108 apted pathobiota." Under this framework, the critically ill patient is viewed as a host colonized by

109 e the performance of blood glucose meters in critically ill patient settings.

110 A critically ill patient with multiple postoperative infec

111 We enrolled critically ill patients (>/=18 years) needing mechanical

112 Critically ill patients 6 months to 5 years old.

113 conducted a prospective cohort study of 350 critically ill patients admitted to intensive care units

114 Delayed gastric emptying occurs in critically ill patients and impairs the delivery, digest

115 Focus on critically ill patients and included evaluations in othe

116 Surgical and critically ill patients at a tertiary medical center bet

117 Diaphragm muscle fibers from critically ill patients displayed significant atrophy an

118 Critically ill patients have manifest diaphragm muscle f

119 Chronically critically ill patients have recurrent infections, organ

120 Delirium in critically ill patients is associated with poor clinical

121 ntinuous electroencephalography (EEG) use in critically ill patients is expanding.

122 h combined antibiotic and steroid therapy in critically ill patients not fitting into established dis

123 ecision-making by surrogates for chronically critically ill patients on mechanical ventilation.

124 and will advance the study and management of critically ill patients requiring mechanical ventilation

125 To observe how surrogates of chronically critically ill patients respond to information about pro

126 ere form of antibiotic-associated colitis in critically ill patients signified by microbiota depletio

127 Accurate diagnosis for Arabic speaking critically ill patients suffering from delirium is limit

128 The diverse responses of critically ill patients to infection with multi-drug res

129 e accuracy in predicting 6-month outcomes of critically ill patients varied depending on the outcome

130 systemic inflammatory markers compared with critically ill patients who do not develop ICU-acquired

131 Among critically ill patients with acute kidney injury, exposu

132 Whether earlier initiation of RRT in critically ill patients with AKI can improve outcomes re

133 d easily available technique for identifying critically ill patients with intracranial hypertension.

134 mendations for the use of corticosteroids in critically ill patients with sepsis and septic shock, ac

135 tcomes of atrial fibrillation in a cohort of critically ill patients with sepsis.

136 nt of acute respiratory distress syndrome in critically ill patients with sepsis.

137 thms to decrease duration of antibiotics for critically ill patients with sepsis.

138 presentation, outcome, and host response in critically ill patients with sepsis.

139 PATIENTS/Twenty-six critically ill patients with Sequential Organ Failure As

140 viral replication patterns, and outcomes of critically ill patients with severe acute respiratory in

141 gest that we should limit the PaO2 levels of critically ill patients within a safe range, as we do wi

142 compared with placebo or no intervention in critically ill patients without neutropenia, but the qua

143 It allows prolonged hemodialysis sessions in critically ill patients without the need to systemically

144 eding versus Target Enteral Feeding in Adult Critically Ill Patients) trial.

145 e improvement for treatment of infections in critically ill patients, are lacking.

146 de YY and ghrelin in control subjects and in critically ill patients, during feeding and fasting, and

147 Newly admitted critically ill patients, greater than or equal to 48 hou

148 In critically ill patients, infusing glucose with insulin d

149 ncentives for physicians to provide care for critically ill patients, particularly at institutions wi

150 In critically ill patients, plasma concentration of ghrelin

151 e, blood pressure, and heart rate in febrile critically ill patients.

152 ains a major cause of respiratory failure in critically ill patients.

153 clinical judgment of the risk of seizures in critically ill patients.

154 s and leading to questions over their use in critically ill patients.

155 ily risk of individual organ dysfunctions in critically ill patients.

156 tributor to weaning difficulty in ventilated critically ill patients.

157 atients was observed in this large cohort of critically ill patients.

158 s commonly used to assess immune function in critically ill patients.

159 ed with increased morbidity and mortality in critically ill patients.

160 of AKI, death, and other adverse outcomes in critically ill patients.

161 and contractile weakness of the diaphragm in critically ill patients.

162 lly in hospitalized and immunocompromised or critically ill patients.

163 amage in mechanically ventilated and sedated critically ill patients.

164 ety of withholding proton pump inhibitors in critically ill patients.

165 ng the persisting poor outcomes for infected critically ill patients.

166 utilized to fill resource gaps in caring for critically ill patients.

167 racy of a blood glucose monitoring system in critically ill patients.

168 ability are associated with poor outcomes in critically ill patients.

169 in modifies duration of delirium and coma in critically ill patients.

170 o assess the performance of Septicyte Lab in critically ill pediatric patients.

171 risk evaluated by the NUTrition Risk in the Critically Ill score.

172 There may be excess morbidity in critically ill selective serotonin reuptake inhibitor/se

173 he administration of the ESA epoetin alfa to critically ill trauma patients has been associated with

174 nce on safe medication use practices for the critically ill.

175 lasma concentration-time data from 214 adult critically-ill patients (creatinine clearance 0-236mL/mi

176 In this review, we critically illustrate the current landscape of novel the

177 es in the climate and population growth will critically impact the future supply and demand of water,

178 es for the perovskite crystallization, which critically impacts morphology, crystal quality, and opto

179 4-induced changes, repression of fibronectin critically impaired the human keratinocyte wound respons

180 f tau and trigger a cascade of neurotoxicity critically impinging on the integrity of the actin cytos

181 logy, engineering, and mathematics (STEM) is critically important as preparation to pursue STEM caree

182 onreplicating persistence, both of which are critically important aspects of M. tuberculosis pathogen

183 usly we observed increased expression of the critically important beta-cell gene, Igf2 in whole F1 em

184 to develop small molecule inhibitors of this critically important enzyme that is an active target for

185 The generation of tumour-specific T cells is critically important for cancer immunotherapy.

186 Likewise, apolipoprotein E (apoE) is critically important for HCV cell-to-cell spread, unlike

187 d that the hypusine modification on eIF5A is critically important for poor substrates like proline.

188 erent nucleotide states of the Fe protein is critically important for understanding the Fe protein cy

189 ynthetic rates and N-use efficiency of these critically important forests.

190 rkers in biological media, such as serum, is critically important in detecting disease or physiologic

191 drugs through various molecular features is critically important in the discovery of new therapeutic

192 JMJD3 in naive CD4 T cells demonstrates how critically important molecules required for T cell diffe

193 We conclude that IsaR1 is a critically important riboregulator.

194 en climatic variation and fire activity is a critically important scientific question.

195 oietic stem cell transplantation (HSCT) is a critically important therapy for hematological malignanc

196 ct trees from trees computed on subsets, are critically important tools for enabling the statistical

197 median, mean, and proportion rating 7 to 9 (critically important), and analyzed comments thematicall

198 , but that the expression of contempt varies critically in relation to the socioecological context.

199 le to teach primary school children to think critically in schools with large student to teacher rati

200 nsmembrane AMPAR regulatory proteins (TARPs) critically influence the distribution, gating, and pharm

201 Together, the CAMKIIgamma:c-Myc axis critically influences the development and maintenance of

202 phenotypes, and requires validation in other critically injured cohorts.

203 and flow cytometry analyses on a total of 70 critically injured patients (Injury Severity Score [ISS]

204 cripts (4%) were differentially expressed in critically injured patients.

205 It critically investigates whether data-driven UWM offers a

206 that macrophages and their M1/M2 activation critically involve in the hepatoprotection conferred by

207 ission in the central nervous system and are critically involved in brain function.

208 Notably, the three GEFs are all critically involved in chemokine-induced RhoA and Rac1 a

209 Molecules critically involved in cocaine behavioral plasticity are

210 doptive experiments revealed that Tregs were critically involved in CTL tolerance.

211 raventricular nucleus (PVN) is increased and critically involved in heightened sympathetic vasomotor

212 T helper 17 (TH17) cells are critically involved in host defence, inflammation, and a

213 ells and their microenvironment as a process critically involved in liposarcoma progression.

214 ian NAD(+)-dependent protein deacetylase, is critically involved in modulating methionine metabolism,

215 In Drosophila, the mushroom body (MB) is critically involved in olfactory classical conditioning,

216 eta/gamma can modulate p53 functions and are critically involved in regulation of cellular response t

217 sary for reward behavior with dopamine cells critically involved in reward signaling.

218 of the DEAH-box RNA helicase DHX33, which is critically involved in ribosomal RNA synthesis and mRNA

219 We demonstrate that SPOP is critically involved in SETD2 stability control and that

220 -transcription coupling pathways shown to be critically involved in structural and functional remodel

221 kidney injury, and suggest that JG cells are critically involved in the maintenance and protection of

222 o reduce cortical dopamine release, which is critically involved in the reinforcing effect of tobacco

223 or-inducing interferon-gamma (TRIF), factors critically involved in the TLR signaling pathway, was st

224 Thus, S1 is critically involved in updating the memory about the per

225 The "art form" of parent-infant bonding critically involves baby conveying negative emotions - l

226 Successful decision making critically involves metacognitive processes such as moni

227 amine processing of motivated behavior; most critically, it indicates that dopamine neurons selective

228 However, we critically lack quantification of basic biomechanical pa

229 el in which genome folding and misfolding is critically linked to the onset and progression of a broa

230 g the channel availability, a mechanism that critically links cellular properties of T-type Ca(2+) ch

231 Simulations suggest that critically low temperatures, rather than high temperatur

232 Heparan sulfate proteoglycans (HSPGs) critically modulate adhesion-, growth-, and migration-re

233 ctivated protein kinases (MAPKs) and thereby critically modulate cell proliferation and differentiati

234 that specific Runx1-bound enhancer elements critically modulate lineage-dependent expressions of PLZ

235 pathogenesis of neurodegenerative disorders, critically modulating the early stages of cognitive decl

236 ive solution to obtaining lightweight metals critically needed for future energy efficiency and fuel

237 tial strongly supports that iNSCs may be the critically needed therapeutic for human stroke patients.

238 ements on the spread of both viruses depends critically on assumptions made about the distances over

239 ne stereoscopic depth discriminations depend critically on comparisons of disparity relationships in

240 establishing a new population often depends critically on finding mates, individuals capable of unip

241 f advanced energy-conversion systems depends critically on our understanding of the fundamental inter

242 blages on herbivores are predicted to depend critically on predator-predator interactions and the ext

243 that context-dependent gamma rhythms depend critically on SOM interneurons.

244 essful establishment of seedlings may depend critically on the balance between the novelty and famili

245 of symptom monitoring and quarantine depends critically on the natural history of the infectious dise

246 rm that this competition should take depends critically on the noise corrupting these signals.

247 The normal function of ion channels depends critically on the precise subcellular localization and t

248 n membrane proteins and drug targets-depends critically on their ability to change shape, transitioni

249 Critically, on these trials the initial grip force was m

250 Critically, our understanding of ROS-mediated PTP oxidat

251 ing and executive functions, (2) suggest how critically reconsidering the role of the frontal cortex

252 Our biological studies suggest that a critically reduced amount of this protein alters cell sh

253 NG ENZYME) NEDD8 thioester levels, either by critically reducing the pool of free NEDD8 or by reducin

254 zing diverse elements within the enzyme that critically regulate catalytic activity.

255 However, most JmjC genes do not critically regulate development, as 10 members are viabl

256 NAs (miRNAs) and RNA-binding proteins (RBPs) critically regulate gene expression programs in mammalia

257 non-coding RNAs (lncRNAs) have been shown to critically regulate gene expression, only a fraction of

258 Long-range enhancer interactions critically regulate gene expression, yet little is known

259 e largest family of signaling receptors, are critically regulated by endosomal trafficking, suggestin

260 LTP in the CA3-CA1 hippocampal projection is critically regulated by the activity of matrix metallopr

261 icient mice, suggesting that IFNAR signaling critically regulates BBB permeability in this brain regi

262 Membrane traffic critically regulates most aspects of neuronal function.

263 lator of G protein signaling family (R7-RGS) critically regulates nervous system development and func

264 The endocannabinoid (eCB) system critically regulates stress responsivity and anxiety thr

265 sion, this study has demonstrated that VISTA critically regulates the inflammatory responses mediated

266 This is true for the heart, whose function critically relies on well-ordered communication between

267 In addition, GABP is critically required for antigen-stimulated T-cell respon

268 strate that polar secretion of substrates is critically required for Legionella's alteration of the h

269 vation of NF-kappaB transcription factors is critically required for Treg cell development, partly vi

270 We critically review progress in imaging genetics and offer

271 f AHSV remains a major research focus and we critically review studies that have implicated both Culi

272 In this Perspective, we will critically review the clinical and neuroimaging evidence

273 Here, we critically review the current evidence for a role of the

274 We critically review the current state of structural neuroi

275 In this study, we critically review the proposed mechanisms whereby exempl

276 nt end-of-use options for these polymers are critically reviewed, with a focus on recent advances in

277 Recent progress made in the field of ASCs is critically reviewed, with the main focus on an extensive

278 es, especially for large scale synthesis, is critically reviewed.

279 Critically, reward devaluation by both cognitive and phy

280 telomere attrition, resulting in cells with critically short and unprotected telomeres.

281 In the second phase, the critically short telomeres lead to genome instability an

282 Critically, such developmental changes within PSCs were

283 developed using evidence-based methodology, critically synthesises surveillance recommendations for

284 We review critically the research related to intracellular antibod

285 Critically, the majority of wheat grain nitrogen is deri

286 Critically, the positive charge of the lysine residues w

287 Most critically, the results show that newborns are capable o

288 Critically, the sterol regulatory binding protein 1 and

289 tic capabilities), their key properties, and critically their likelihood to be clinically translated.

290 Critically, these effects are reproduced by Aurora A inh

291 Critically, these metagenes also have predictive value r

292 Critically, these results were independent of encoding-r

293 Critically, these visual maps constitute well-defined an

294 Critically, this work provides in vivo evidence that dif

295 B cells contribute critically to an effective immune response by producing

296 riggered upon F-actin binding and contribute critically to the mechanochemical behavior of stress fib

297 er, the success of these initiatives depends critically upon understanding how landscape change affec

298 Most critically we report major declines in shallow fore-reef

299 Critically, we must be able to correctly assign credit f

300 Critically, we observed these differences between single