ライフサイエンスコーパス: critically ill

1 esponses from surrogates for the chronically critically ill.

2 n associated with increased mortality in the critically ill.

3 6) levels in CMV-seropositive adults who are critically ill.

4 key trials of circadian interventions in the critically ill.

5 ian-rhythm-restoring interventions among the critically ill.

6 ian rhythms are severely disrupted among the critically ill.

7 ive studies of tracheostomy insertion in the critically ill.

8 nce on safe medication use practices for the critically ill.

9 overall ejection fraction was reduced in the critically ill (50% [8-83%] vs 77 [72-84%]; p = 0.01].

10 critically ill, fasting gallbladder volumes (critically ill, 61 mL [36-100 mL] vs healthy, 22 mL [15-

11 H circuit.This was a prospective study in 10 critically ill adult patients who received CVVH from Apr

12 Frailty is common in critically ill adults aged 18 years and older and is ind

13 IONALE: The optimal nutritional strategy for critically ill adults at high nutritional risk is unclea

14 n of systemic candidiasis in immunocompetent critically ill adults did not reduce mortality and may h

15 als in their decisions related to liberating critically ill adults from mechanical ventilation.

16 electroencephalographic recordings from 4772 critically ill adults in 3 academic medical centers from

17 el has not been shown to improve outcomes in critically ill adults or children after cardiac surgery.

18 Critically ill adults requiring continuous renal replace

19 of nutritional interventions administered to critically ill adults that had mortality as the primary

20 randomized, double-blind trial, we assigned critically ill adults to receive either the freshest ava

21 Forty critically ill adults with fever (core temperature, >/=

22 essenger RNAs, was developed to discriminate critically ill adults with infection-positive versus inf

23 y available transcriptomic data representing critically ill adults with sepsis from which the sepsis

24 ties and associations of free light chain in critically ill adults with sepsis have not been previous

25 ravenous fluid most commonly administered to critically ill adults, but it may be associated with acu

26 Eligible trials enrolled at least 100 critically ill adults, children, or neonates, evaluated

27 Among febrile critically ill adults, treatment with acetaminophen decr

28 jury is associated with delirium and coma in critically ill adults.

29 cells did not affect 90-day mortality among critically ill adults.

30 ge affects mortality after transfusion among critically ill adults.

31 otocols impact patient-important outcomes in critically ill adults.

32 ze liberation from mechanical ventilation in critically ill adults.

33 rol (placebo, no protocol, or usual care) in critically ill adults.

34 o determine the impact of bowel protocols in critically ill adults.

35 to liberation from mechanical ventilation in critically ill adults.

36 osocomial infections, particularly affecting critically ill and immunocompromised patients.

37 in the intensive care setting, affecting the critically ill and the immunocompromised.

38 We included infants who were not critically ill and whose family refused admission.

39 edictors, and consequences of delirium among critically ill Arabic speaking patients.

40 Overall risk of mortality in severely anemic critically ill bloodless patients appeared to be compara

41 impact the choice of empiric antibiotics in critically ill burn patients.

42 ociated with an extremely poor outcome among critically ill burn patients.

43 cant interaction among NUTrition Risk in the Critically Ill category, mortality, and protein and ener

44 cant interaction among NUTrition Risk in the Critically Ill category, time to discharge alive, and pr

45 tive observational cohort study included all critically ill children 21 years or younger admitted to

46 first-line mode of mechanical ventilation in critically ill children admitted to PICU in an unplanned

47 To determine prevalence of delirium in critically ill children and explore associated risk fact

48 Delirium occurs frequently in critically ill children and is independently associated

49 diatric version of the SOFA score (pSOFA) in critically ill children and to evaluate the Sepsis-3 def

50 s collected from central venous catheters in critically ill children and to examine the effect of the

51 tcomes, including increased mortality, among critically ill children and young adults.

52 nal interventions on clinical outcomes among critically ill children in a United Kingdom study.

53 parenteral nutrition on clinical outcomes in critically ill children is unclear.

54 randomized, controlled trial involving 1440 critically ill children to investigate whether withholdi

55 Studies involving critically ill children who have not undergone cardiac s

56 In a 35-center trial, we randomly assigned critically ill children with confirmed hyperglycemia (ex

57 Critically ill children with hyperglycemia did not benef

58 ere to describe the frequency of delirium in critically ill children, its duration, associated risk f

59 Delirium is prevalent among critically ill children, yet associated outcomes and mod

60 actors for iatrogenic withdrawal syndrome in critically ill children.

61 ent, to date, of the Sepsis-3 definitions in critically ill children.

62 and validated with age-adjusted variables in critically ill children.

63 dern model of circadian disruption among the critically ill, discuss causes of these circadian arrhyt

64 TMA presentations in the critically ill, drug-induced TMA, cancer-associated TMA,

65 The high mortality rate in critically ill elderly patients has led to questioning o

66 Among critically ill elderly patients in France, a program to

67 For chronically critically ill elderly patients on mechanical ventilatio

68 commendation for systematic ICU admission in critically ill elderly patients reduces 6-month mortalit

69 In the critically ill, fasting gallbladder volumes (critically

70 l, < 5) and high-risk (NUTrition Risk in the Critically Ill, >/= 5) patients, mortality and time to d

71 the idea of noninfectious sepsis given that critically ill humans never exist in a germ-free state.

72 ntify the impact of antifungal prevention in critically ill immunocompetent adult patients on mortali

73 Critically ill immunocompromised patients with hypoxemic

74 ntrolled trial of noninvasive ventilation in critically ill immunocompromised patients with hypoxemic

75 Critically ill individuals experience a significantly gr

76 panded testing and whole-exome sequencing in critically ill infants and emphasize the importance of a

77 ffect on medical management among a group of critically ill infants who were suspected to have geneti

78 werful tool for the diagnostic evaluation of critically ill infants with suspected monogenic disorder

79 ield and use of clinical exome sequencing in critically ill infants.

80 278) were taken from a prospective study of critically ill intensive care unit (ICU) patients meetin

81 semi-structured interviews with chronically critically ill long-term acute care hospital patients or

82 In low-risk (NUTrition Risk in the Critically Ill, < 5) and high-risk (NUTrition Risk in th

83 uantify diaphragm atrophy in a population of critically ill mechanically ventilated patients with ult

84 Immunoneutralizing glucagon in critically ill mice only transiently affected glucose an

85 In critically ill mice, infusion of amino acids increased g

86 Critically ill morbidly obese patients pose considerable

87 n the intensive care setting when caring for critically ill morbidly obese patients.

88 linical data from 16 mechanically ventilated critically ill obese patients were analyzed.

89 Atelectasis develops in critically ill obese patients when undergoing mechanical

90 PATIENTS/Critically ill obese patients with acute respiratory fai

91 However, while these patients are less critically ill on admission than patients with necrotizi

92 lidity of whole blood glucose measurement in critically ill patient care settings.

93 apted pathobiota." Under this framework, the critically ill patient is viewed as a host colonized by

94 monitoring system was acceptable for use in critically ill patient settings when compared to the cen

95 e the performance of blood glucose meters in critically ill patient settings.

96 A critically ill patient with multiple postoperative infec

97 We enrolled critically ill patients (>/=18 years) needing mechanical

98 In five critically ill patients (21%), there was no change in ga

99 ) and the need to admit and provide care for critically ill patients (demand).

100 admission until day 5 of the ICU stay in 30 critically ill patients (median [interquartile range] ag

101 tion bays caring for a series of 3 simulated critically ill patients (sepsis, seizure, and cardiac ar

102 Critically ill patients 6 months to 5 years old.

103 Critically ill patients admitted between July 2000 and O

104 conducted a prospective cohort study of 350 critically ill patients admitted to intensive care units

105 All consecutive critically ill patients admitted with sepsis, involving

106 iated with adjusted 90-day mortality risk in critically ill patients admitted with sepsis.

107 eligible studies that randomly assigned 2607 critically ill patients after trauma to an ESA or placeb

108 r, cluster-randomized clinical trial of 3037 critically ill patients aged 75 years or older, free of

109 hragm biopsies of 36 mechanically ventilated critically ill patients and compared with those isolated

110 Constipation is common among critically ill patients and has been associated with adv

111 Nonhypoxemic mechanically ventilated critically ill patients and healthy volunteers served as

112 Delayed gastric emptying occurs in critically ill patients and impairs the delivery, digest

113 Focus on critically ill patients and included evaluations in othe

114 te kidney injury is a common complication in critically ill patients and is associated with increased

115 tudy describes the experience of chronically critically ill patients and surrogates in an long-term a

116 n of pantoprazole to mechanically ventilated critically ill patients anticipated to receive enteral n

117 Studies showing this relationship in critically ill patients are lacking, whereas clearance o

118 tor to high healthcare costs associated with critically ill patients as it has been shown that, despi

119 Surgical and critically ill patients at a tertiary medical center bet

120 used for inhalational long-term sedation in critically ill patients at risk to develop epilepsy, our

121 gained from randomized controlled trials in critically ill patients by assessing the incidence of el

122 (RBC) transfusion poses significant risks to critically ill patients by increasing their susceptibili

123 Diaphragm muscle fibers from critically ill patients displayed significant atrophy an

124 We studied 1,558 critically ill patients enrolled in a prospective observ

125 Pantoprazole is frequently administered to critically ill patients for prophylaxis against gastroin

126 n, 2000, and Dec, 2014, we studied 1 028 235 critically ill patients from 182 ICUs across Australia a

127 opulation, and the handover and transport of critically ill patients from the emergency room to the i

128 Critically ill patients have manifest diaphragm muscle f

129 in some observational studies, but trials in critically ill patients have not shown benefit.

130 Chronically critically ill patients have recurrent infections, organ

131 assess the reliability of codes relevant to critically ill patients in administrative data.

132 tient populations at risk were most commonly critically ill patients in adult and neonatal intensive

133 ies to optimize the support of the family of critically ill patients in the ICU.

134 d Services stating that the use of meters in critically ill patients is "off-label" and constitutes "

135 that weakness of diaphragm muscle fibers in critically ill patients is accompanied by impaired mitoc

136 Delirium in critically ill patients is associated with poor clinical

137 inical significance of diaphragm weakness in critically ill patients is evident: it prolongs ventilat

138 ntinuous electroencephalography (EEG) use in critically ill patients is expanding.

139 In sepsis, the disease course of critically ill patients is often complicated by muscle f

140 ospectively associated with AKI and death in critically ill patients is unknown.

141 Physicians who care for critically ill patients need to be cognizant of the accu

142 h combined antibiotic and steroid therapy in critically ill patients not fitting into established dis

143 re routine screening for clinical frailty in critically ill patients of all ages.

144 We enrolled 136 critically ill patients on mechanical ventilation and/or

145 ecision-making by surrogates for chronically critically ill patients on mechanical ventilation.

146 Over 30% of critically ill patients on positive-pressure mechanical

147 ues may result in improved identification of critically ill patients on the wards.

148 pain (September 2012-October 2014) including critically ill patients ready for planned extubation wit

149 Hence, critically ill patients receiving CYP3A substrate drugs

150 re to account for this source of calories in critically ill patients receiving nutrition on CVVH may

151 In this study, most caregivers of critically ill patients reported high levels of depressi

152 and will advance the study and management of critically ill patients requiring mechanical ventilation

153 To observe how surrogates of chronically critically ill patients respond to information about pro

154 A large portion of former critically ill patients show small fiber deficits which

155 ere form of antibiotic-associated colitis in critically ill patients signified by microbiota depletio

156 ential harm from unnecessary oxygen therapy, critically ill patients spend substantial periods in a h

157 Accurate diagnosis for Arabic speaking critically ill patients suffering from delirium is limit

158 Twenty-four mechanically ventilated critically ill patients suitable to receive enteral nutr

159 nt syndrome of acute brain dysfunction among critically ill patients that has been linked to multiple

160 tively common for pediatricians who care for critically ill patients to encounter families who object

161 The diverse responses of critically ill patients to infection with multi-drug res

162 Critically ill patients transported within the hospital

163 Among critically ill patients treated in ICUs in Brazil, imple

164 Anemic critically ill patients treated with IV iron and healthy

165 Critically ill patients typically present with hyperglyc

166 In critically ill patients undergoing EEG recordings, SIRPI

167 e accuracy in predicting 6-month outcomes of critically ill patients varied depending on the outcome

168 Almost one-third of mechanically ventilated critically ill patients were rehospitalized at a differe

169 systemic inflammatory markers compared with critically ill patients who do not develop ICU-acquired

170 Critically ill patients who have a high risk of bleeding

171 Critically ill patients who have bacteremia typically re

172 Glucose measurements were performed on 1,698 critically ill patients with 257 different clinical cond

173 Among critically ill patients with acute kidney injury, exposu

174 he Early Versus Delayed Initiation of RRT in Critically Ill Patients with AKI (ELAIN) Trial from 90 d

175 Whether earlier initiation of RRT in critically ill patients with AKI can improve outcomes re

176 ngle-center randomized clinical trial of 231 critically ill patients with AKI Kidney Disease: Improvi

177 conclusion, early initiation of RRT in these critically ill patients with AKI significantly reduced t

178 Among critically ill patients with AKI, early RRT compared wit

179 ets to improve mortality and resource use in critically ill patients with cancer.

180 nd October 2015 were compared to consecutive critically ill patients with community-acquired severe a

181 clusions and Relevance: Among nonneutropenic critically ill patients with ICU-acquired sepsis, Candid

182 esources, and treatments with outcomes among critically ill patients with influenza A (H1N1pdm09) in

183 d easily available technique for identifying critically ill patients with intracranial hypertension.

184 We studied 16,968 critically ill patients with Kidney Disease Improving Gl

185 Critically ill patients with laboratory-confirmed Middle

186 The mortality for critically ill patients with melioidosis in the Top End

187 anagement, and outcomes of a large cohort of critically ill patients with melioidosis.

188 mendations for the use of corticosteroids in critically ill patients with sepsis and septic shock, ac

189 Among 20750 critically ill patients with sepsis in 107 hospitals wit

190 We sought to determine PCT use in critically ill patients with sepsis in the United States

191 nsfusion did not affect overall mortality in critically ill patients with sepsis.

192 A total of 1,080 critically ill patients with sepsis.

193 presentation, outcome, and host response in critically ill patients with sepsis.

194 tcomes of atrial fibrillation in a cohort of critically ill patients with sepsis.

195 nt of acute respiratory distress syndrome in critically ill patients with sepsis.

196 thms to decrease duration of antibiotics for critically ill patients with sepsis.

197 PATIENTS/Twenty-six critically ill patients with Sequential Organ Failure As

198 Critically ill patients with severe (n = 21) or non-seve

199 In a trial involving critically ill patients with severe acute kidney injury,

200 viral replication patterns, and outcomes of critically ill patients with severe acute respiratory in

201 his individual patient data meta-analysis of critically ill patients with severe sepsis, we aimed to

202 ttent infusion of beta-lactam antibiotics in critically ill patients with severe sepsis.

203 sed prediction model for 28-day mortality in critically ill patients with SIRS and sepsis.

204 Critically ill patients with stable renal function (n =

205 Critically ill patients with subarachnoid hemorrhage sho

206 In critically ill patients with type 2 diabetes and chronic

207 gest that we should limit the PaO2 levels of critically ill patients within a safe range, as we do wi

208 PRoVENT (PRactice of VENTilation in critically ill patients without ARDS at onset of ventila

209 compared with placebo or no intervention in critically ill patients without neutropenia, but the qua

210 diagnosis of an invasive fungal infection in critically ill patients without neutropenia?

211 It allows prolonged hemodialysis sessions in critically ill patients without the need to systemically

212 eding versus Target Enteral Feeding in Adult Critically Ill Patients) trial.

213 4-10) during 51 intrahospital transports of critically ill patients, 80% of whom were mechanically v

214 ry coordination, labor-intensive support for critically ill patients, and effective chronic disease m

215 pharmacologic treatment, glucose targets for critically ill patients, and treatment of hospitalized p

216 e improvement for treatment of infections in critically ill patients, are lacking.

217 Chronically critically ill patients, defined by tracheotomy for prol

218 de YY and ghrelin in control subjects and in critically ill patients, during feeding and fasting, and

219 In critically ill patients, elevated blood lactate at admis

220 Among critically ill patients, exposure to positive or negativ

221 Newly admitted critically ill patients, greater than or equal to 48 hou

222 In this large cohort of critically ill patients, increased concentrations of lac

223 In critically ill patients, infusing glucose with insulin d

224 propose the evolution of a new phenotype of critically ill patients, its potential underlying mechan

225 In a large heterogenous cohort of critically ill patients, low admission peak plasma creat

226 ncentives for physicians to provide care for critically ill patients, particularly at institutions wi

227 sociated with development of ARDS in at-risk critically ill patients, particularly in trauma patients

228 In critically ill patients, plasma concentration of ghrelin

229 t the value of greater nutritional intake in critically ill patients, possibly due to varied patient

230 This Review surveys the microbial ecology of critically ill patients, presents the facts and unanswer

231 Thus, among critically ill patients, sepsis and non-infective SIRS a

232 showed marked small nerve fiber pathology in critically ill patients, which may contribute to chronic

233 ional outcomes influence decision making for critically ill patients, yet little is known regarding t

234 spective follow-up analysis from a cohort of critically ill patients.

235 afe medication practices that is specific to critically ill patients.

236 surgery, but possibly increase morbidity in critically ill patients.

237 ble instruments are difficult to complete in critically ill patients.

238 monitoring duration for seizure detection in critically ill patients.

239 racy of a blood glucose monitoring system in critically ill patients.

240 ng the process of intrahospital transport of critically ill patients.

241 nt factor in the unexplained anemias seen in critically ill patients.

242 ave been associated with risk of seizures in critically ill patients.

243 inst the profound pathologies encountered in critically ill patients.

244 whether physician diversity reflects that of critically ill patients.

245 ability are associated with poor outcomes in critically ill patients.

246 th clinically relevant outcomes in extubated critically ill patients.

247 acokinetics has been poorly studied in obese critically ill patients.

248 f contrast-associated acute kidney injury in critically ill patients.

249 (step and global position system) data from critically ill patients.

250 ospital transport is a hazardous process for critically ill patients.

251 tions arising through the day-to-day care of critically ill patients.

252 otonin-norepinephrine reuptake inhibitors in critically ill patients.

253 l infection in recipients are often found in critically ill patients.

254 te translocation of bacteria to the lungs in critically ill patients.

255 anxiety, and stress disorders in families of critically ill patients.

256 in modifies duration of delirium and coma in critically ill patients.

257 xiety, and acute stress in family members of critically ill patients.

258 specially common in individuals who care for critically ill patients.

259 placement is a common procedure performed on critically ill patients.

260 ion after subarachnoid hemorrhage similar to critically ill patients.

261 e, blood pressure, and heart rate in febrile critically ill patients.

262 ains a major cause of respiratory failure in critically ill patients.

263 clinical judgment of the risk of seizures in critically ill patients.

264 s and leading to questions over their use in critically ill patients.

265 ily risk of individual organ dysfunctions in critically ill patients.

266 tributor to weaning difficulty in ventilated critically ill patients.

267 atients was observed in this large cohort of critically ill patients.

268 s commonly used to assess immune function in critically ill patients.

269 ed with increased morbidity and mortality in critically ill patients.

270 of AKI, death, and other adverse outcomes in critically ill patients.

271 and contractile weakness of the diaphragm in critically ill patients.

272 lly in hospitalized and immunocompromised or critically ill patients.

273 amage in mechanically ventilated and sedated critically ill patients.

274 ety of withholding proton pump inhibitors in critically ill patients.

275 ng the persisting poor outcomes for infected critically ill patients.

276 utilized to fill resource gaps in caring for critically ill patients.

277 lasma concentration-time data from 214 adult critically-ill patients (creatinine clearance 0-236mL/mi

278 of off-target ventilation (OTV) delivery in critically-ill patients.

279 tients, hospitalized patients (including the critically ill), patients undergoing stress echocardiogr

280 were identified regarding transportation of critically ill pediatric patients from the emergency roo

281 o assess the performance of Septicyte Lab in critically ill pediatric patients.

282 output estimation in a large and nonselected critically ill population.

283 to other VAD populations, despite being more critically ill pre-implantation.

284 When caring for the critically ill, resilient family members have fewer symp

285 Based on the Nutrition Risk in Critically Ill score, 378 of 894 (42.3%) patients were c

286 ategorized by the modified Nutrition Risk in Critically Ill score, with high nutritional risk defined

287 risk evaluated by the NUTrition Risk in the Critically Ill score.

288 There may be excess morbidity in critically ill selective serotonin reuptake inhibitor/se

289 Of all consecutive critically ill sepsis patients, admission glucose was us

290 mpact of antipyretic therapy on mortality in critically ill septic adults.

291 rceptions and current guidelines for care of critically ill septic patients, increased body temperatu

292 tive fluid balance and hospital mortality in critically ill septic patients.

293 Consecutive critically ill severely obese (body mass index, > 35 kg/

294 in RCTs of nutritional interventions in the critically ill that are powered to determine a mortality

295 a concentration variability would expose the critically ill to both piperacillin under and overdosing

296 performed a retrospective registry study of critically ill trauma patients 18 years or older with ch

297 he administration of the ESA epoetin alfa to critically ill trauma patients has been associated with

298 The administration of ESAs to critically ill trauma patients is associated with a sign

299 erythropoiesis-stimulating agents (ESAs) in critically ill trauma patients.

300 e points for outcomes among patients who are critically ill with suspected infection.