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1 H2B cross-links as well as inter-nucleosomal cross-links.
2 histidine, lysine, and free cysteine to form cross-links.
3 fied residues, attachment modifications, and cross-links.
4 radiated with UV light to induce protein-RNA cross-links.
5 ydrogel expansion by successive extension of cross-links.
6 roximately 300 kDa or >300 kDa that had been cross-linked.
7 ficial protease FeBABE and cysteine-cysteine cross-linking.
8 d-loaded particles using streptavidin-biotin cross-linking.
9 to this biosynthetic pathway to complete the cross-linking.
10 f elastic fibers in vivo, preceding chemical cross-linking.
11 that FKBP65 regulates LH2-mediated collagen cross-linking.
12 and neovessel branching increase with matrix cross-linking.
13 tuned from extensile to contractile through cross-linking.
14 ir wild-type counterparts in response to BCR cross-linking.
15 vel of downstream, rather than overall, Taf1 cross-linking.
16 current clamp recordings, microinjection of cross-linked 300 kDa increased excitability by depolariz
17 enabled tracking of the effect of the shell cross-linking ability of laccase, or CaCl2, on microcaps
18 by mechanical stresses that develop within a cross-linked actin gel that forms at localized regions o
19 predict the viscoelastic scaling behavior of cross-linked actin networks, characterize the trajectori
20 impairs lipid II polymerization and peptide cross-linking activities of PBP1b, and that PBP3 relieve
21 this study, which compares the peptidoglycan cross-linking activity of PBP2b from susceptible and res
24 enous source of glyoxal, levels of these two cross-linked adducts were found to be significantly high
27 an be defined by incorporating a multivalent cross-linking agent, and this approach has been successf
35 ed these structures by site-directed protein cross-linking and hydroxyl radical footprinting experime
37 osteclosion and 24 h PBM through Argonaute 1 cross-linking and immunoprecipitation followed by high-t
38 yl oxidase-like 2 (LOXL2) catalyses collagen cross-linking and is implicated in the pathogenesis of i
40 ormation of allysine, which enables collagen cross-linking and leads to tissue stiffening and scar fo
43 r with complementary restraints derived from cross-linking and native MS, we built native-like models
44 n-scaffold linkage: genetic fusion, chemical cross-linking and plug-and-display SpyTag/SpyCatcher con
45 released from hydrogel decreased by citrate cross-linking and was higher at neutral pH than pH 2.0.
46 are transpeptidases that form peptidoglycan cross-links, and low-molecular-weight PBPs, which are ty
47 eplication-coupled repair of interstrand DNA cross-links, and mitigate conflicts between replication
54 standards, enzyme hydrolysis to release the cross-links as nucleosides, enrichment by a reversed-pha
55 patch, generating intra-nucleosomal H2A-H2B cross-links as well as inter-nucleosomal cross-links.
57 loyed a new proteomic approach, XAP (in vivo cross-linking-assisted affinity purification), coupled w
58 ectively, identifying 1,158 and 3,301 unique cross-links at approximately 1% false discovery rate.
59 hybrid data acquisition strategy to sequence cross-links at both MS2 and MS3 level and a new algorith
61 quantification of the dG-gx-dC and dG-gx-dA cross-links based on stable isotope dilution (SID) nanof
65 ssue expander comprised only of a chemically cross-linked biocompatible polymeric hydrogel is develop
66 mechanically robust AEMs based on ionically cross-linked blends of spiro-ionene and polybenzimidazol
67 his study were to determine the stability of cross-linked bonds of starch at different pH values and
68 on the pasting property of waxy maize starch cross-linked by 0.05% and 3% sodium trimetaphosphate/sod
70 we present collagen model peptides that are cross-linked by oxime bonds between 4-aminooxyproline (A
72 m responsible for channel gating, we perform cross-linking by bifunctional reagents of multiple predi
73 Reversely, ubiquitous TNFRSF receptor(s) cross-linking by CD40 and Fas agonistic antibodies resul
74 ng by myosin motors, as well as cytoskeletal cross-linking by myosins and nonmotor cross-linkers, are
75 by Capture-C do not depend on the degree of cross-linking by performing experiments with varying for
77 Plasma concentrations of collagen type 1 cross-linked C-telopeptide was significantly decreased i
78 ate (BS3), which is used for protein-protein cross-linking can also be applied for cross-linking prot
80 mediator release assay to determine the IgE cross-linking capability of treated and untreated sample
85 ed on GO-dLPG via EDC/NHS heterobifunctional cross-linking chemistry leaving the binding sites free f
86 hesis that utilizes readily accessible SiCl4 cross-linking chemistry to create durable hybrid solid-e
90 ency and fidelity with which a reduced dG-AP cross-link-containing plasmid was replicated in cultured
94 parative cost-effectiveness of early corneal cross-linking (CXL) and conventional management with pen
97 ssay, which uses time-dependent formaldehyde-cross-linking data to extract kinetic parameters of chro
100 he cooperative effects of both the increased cross-link density given by the reversible iron-catechol
101 strengthening elastomers by increasing their cross-link density leads to embrittlement and decreased
103 he lesion site, whereas replication past the cross-linked dG component occurred at a mutation frequen
104 ttern of a synthetically prepared dityrosine cross-linked dimer of Abeta(1-16) using ESI tandem mass
107 n of network stress depend, individually, on cross-link dynamics and filament turnover, and how these
109 n area >100 cm(2) We found that the collagen cross-linking enzyme lysyl oxidase is expressed in all v
110 lavin dosing intervals with standard corneal cross-linking (epithelial removal and 30-minute irradiat
112 c resonance (NMR) spectroscopy combined with cross-linking experiments and competition-binding assays
116 ng single-molecule fluorescence and in vitro cross-linking experiments with photo-activatable unnatur
120 ers in hippocampal slices using cell-surface cross-linking, followed by Western blot and coimmunoprec
125 latin, that is transformed into an ionically cross-linked hydrated network using biocompatible silica
126 used a comprehensive integrated approach of cross-linking, hydrogen-deuterium exchange mass spectrom
128 apable of unhooking highly toxic interstrand cross-links (ICLs) and bulky minor groove adducts normal
130 -binding sites from peaks identified by Ago2 Cross-Linked ImmunoPrecipitation associated to high-thro
133 or the formation of the unique carbon-carbon cross-link in the streptide family of natural products.
134 oltage sensors, F56Bpa and F57Bpa KCNE1 were cross-linked in open and closed states, respectively, wh
135 o allow photoliberation (uncaging) and photo-cross-linking in a sequential manner, as well as a click
141 e observed a significant rate of misassigned cross-links in a number of publications, mainly due to t
142 o test this hypothesis, we analyzed collagen cross-links in Fkbp10-null and -wild-type murine embryon
144 allowed for the identification of dityrosine cross-links in peptides of Abeta and alpha-synuclein gen
145 e mapping revealed as many as seven covalent cross-links in the HMW fractions, where oxidized histidi
147 self-interaction of the domain, and targeted cross-linking indicates that it forms a multimeric array
148 increased affinity mediates adhesion, LFA-1 cross-linking induced the association and activation of
151 scribed an experimental framework called the cross-linking kinetics (CLK) assay, which uses time-depe
152 ydroxylated lysine-aldehyde-derived collagen cross-links (LCCs), a pattern consistent with loss of LH
153 eversible with DTT treatment, whereas graded cross-link lengthening gradually increased activity, thu
154 EThcD gave the best sequence coverage for cross-linked m/z species with high charge density, while
155 cterial cell walls are composed of the large cross-linked macromolecule peptidoglycan, which maintain
156 of mitochondrial function, we used chemical cross-linking mass spectrometry to identify 2,427 cross-
157 ns, single-particle electron cryomicroscopy, cross-linking mass spectrometry, and structural modeling
158 f Hsp21 based on homology modeling, cryo-EM, cross-linking mass spectrometry, NMR, and small-angle X-
159 rdinates, biochemical analyses and data from cross-linking mass-spectrometry (CLMS), we determine the
160 emplate cores were tested using a reversible cross-linking mechanism, interfacial gelation process or
163 he dense nucleic acid shell of the resulting cross-linked micellar SNA enhances their stability in ph
167 ed this system to investigate the effects of cross-linking MT plus ends and F-actin in Drosophila mel
169 interactions in vivo Some interactions were cross-linked much faster than the in vivo macromolecular
170 introduce for the first time the chemically cross-linked multilayer polyion complex in which SOD1 is
171 (MTs) and active springs that have arms that cross-link neighboring MT pairs and move unidirectionall
172 The hydrogel transitioned from a reversibly cross-linked network formed by dopamine-Laponite interfa
174 ite interfacial interactions to a covalently cross-linked network through the slow autoxidation and c
176 etric identification and characterization of cross-linked nucleic acid-protein heteroconjugates withi
178 more depolarized preopen holding potentials, cross-linking of F57Bpa with KCNQ1 was slowed, which ind
179 ed an ELISA and multiplex assay to model the cross-linking of Fcgamma receptors (FcgammaR) by Abs, wh
186 isopeptide bonds and are widely used for the cross-linking of proteins and peptides in food and biote
187 e of mass spectrometry coupled with chemical cross-linking of proteins has become a powerful tool for
188 ompressibility modulus, whereas fixation and cross-linking of proteins with glutaraldehyde increases
189 col consists of the following steps: in vivo cross-linking of RBPs to their bound RNAs; partial RNA d
190 was synthesized and applied to nanohydrogel cross-linking of self-assembled reactive ester block cop
192 d that DCCD mediates discrete intramolecular cross-links of E. coli TatC involving both its N- and C-
194 nto the effects of an AP-derived interstrand cross-link on the efficiency and accuracy of DNA replica
196 quantify the influence of dreierketten chain cross-linking on the anisotropic mechanical behavior of
197 t contain disulfides, the profound impact of cross-linking on the behavior of the protein polymer, th
200 s that (self-) assemble via the transport of cross-links or defects rather than actual molecules.
201 rest, upon an adaptive-type activation (IgE cross-linking), or upon an innate-type activation (IL-33
204 bled with solid polymer electrolyte based on cross-linked PEEC delivered a high initial discharge cap
205 e major product, MftA*, is a tyramine-valine-cross-linked peptide formed by MftC through two S-adenos
206 -linking mass spectrometry to identify 2,427 cross-linked peptide pairs from 327 mitochondrial protei
207 n tree gave the highest number of identified cross-linked peptide pairs passing a 5% false discovery
209 important role in allowing the detection of cross-linked peptides against the background of linear p
210 se generic fragmentation rules of dityrosine cross-linked peptides allowed for the identification of
214 tri-, or monoglycine), while PBP2a can only cross-link peptidoglycan strands bearing a complete pent
218 ng such silyl ether linkages into covalently cross-linked polymer networks, we demonstrate dynamic co
219 rolling the molecular structure of amorphous cross-linked polymeric materials is a longstanding chall
220 s of academically and industrially important cross-linked polymeric materials, such as resins and gel
225 alysis of the fragmentation behavior of 1065 cross-linked precursors using the five fragmentation tec
227 nked species, an incomplete fragmentation of cross-linked products, and low-mass accuracy fragment io
233 rated that alpha actinin 4 (ACTN4), an actin-cross-linking protein known to coordinate cytoskeletal o
234 x 10(-10)), encoding plectin, a cytoskeletal cross-linking protein that contributes to integrity of c
235 rotein cross-linking can also be applied for cross-linking proteins and phosphatidylethanolamine (PE)
236 works of actin filaments, myosin motors, and cross-linking proteins at biologically relevant time and
238 chastic optical reconstitution microscopy of cross-linked PSGs revealed that PSGs are densely packed
240 s that catalyzes a single intramolecular C-C cross-linking reaction in the biosynthesis of mycocyclos
243 ne units in combination with dehydrogenation cross-linking reactions within the polymer chains leads
244 ound to give robust and site-selective photo-cross-linking reactivity in E. coli when placed at an ap
245 d data suggest that ZapD acts as a molecular cross-linking reagent between FtsZ protofilaments to enh
246 ent of protein-mediated, dynamic chromosomal cross-links recapitulates the segregation, morphology an
250 ranslational modification by positioning the cross-linking residues of the precursor peptide within t
251 strongly hindered protein breakdown, whereas cross-linking resulting from beta-elimination reactions
252 under-hydroxylation effect at helical domain cross-linking sites in skin, bone, tendon, aorta, and co
254 ions, mainly due to the presence of isobaric cross-linked species, an incomplete fragmentation of cro
257 tophoresis (T-ionto CL) and standard corneal cross-linking (standard CL) for the treatment of progres
258 e acylation of the enzymes that catalyze the cross-linking steps in the biosynthesis of their peptido
260 with similar affinities before and after the cross-linking, suggesting that the binding site is prese
263 installation of the characteristic thioether cross-links, tailoring enzymes introduce additional post
264 parently resulting from significant covalent cross-linking that occurs during the treatment of their
265 hat it can also be used to postsynthetically cross-link the aldehyde groups of ZIF-90 using a diamine
266 ensues when multivalent antigens bind to and cross-link the cells' receptor-bound IgE antibodies.
272 beta-sheet peptides to provide non-covalent cross-linking through beta-sheet assembly, reinforced wi
273 structures, we suggest that Ang1 binding may cross-link Tie2 dimers into higher-order oligomers, pote
274 elicited by a vaccine regimen containing Env cross-linked to a CD4-mimetic miniprotein (gp140-M64U1)
275 l groups on the surface of the graphite were cross-linked to amino groups in the enzyme so as to atta
277 Complexes containing EdU-biotin-labeled DNA cross-linked to proteins were captured on streptavidin b
279 me-resolved limited proteolysis and chemical cross-linking to examine nucleotide-induced structural c
280 ere, we have used unnatural amino acid photo-cross-linking to investigate the dynamic interactions th
281 o the ability of the non-covalent beta-sheet cross-links to reassemble, the hydrogels can self-heal a
282 (ZNF598) using PAR-CLIP and revealed that it cross-links to tRNAs, mRNAs and rRNAs, thereby placing t
283 ir of cisplatin-DNA adducts, 1,2-intrastrand cross-links, to potentiate the sensitivity of TGCTs to c
285 -) required for O-O cleavage derive from the cross-linked Tyr residue present at the active site.
286 d DDSs, relying on photoisomerization, photo-cross-linking/un-cross-linking, photoreduction, and so f
287 ules and post self-assembly undergo covalent cross-linking using copper catalyzed click chemistry.
288 clinical outcomes of transepithelial corneal cross-linking using iontophoresis (T-ionto CL) and stand
289 he depth and accuracy in identifying protein cross-links using non-restricted whole proteome database
290 ma-glutamic acid) polymer network physically cross-linked via grafted self-assembling beta-sheet pept
291 us DNA damage, can forge interstrand DNA-DNA cross-links via reaction with the exocyclic amino group
296 sily deform unless the film is enzymatically cross-linked, which promotes the spreading of cells and
297 ermore, we showed that the mechanism of this cross-linking, which involves both singlet oxygen and ra
301 mical proteomics approach relying upon photo-cross-linking with synthetic diazirine-containing RNA pr
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