ライフサイエンスコーパス: crossover

1 ssigned at week 24 to either sirukumab dose (crossover).

2 f injury versus times earlier that day (case-crossover).

3 where a spin-frustrated state emerges at the crossover.

4 cular, the T-dependent incoherence-coherence crossover.

5 e diagram of graphite to exhibit just such a crossover.

6 4 weeks with a 1 week washout period between crossover.

7 ch alleviates the common problem of membrane crossover.

8 2.9; p=0.0048) when analysing the trial as a crossover.

9 c and epigenomic features underlying meiotic crossovers.

10 ce, and increases with the number of genetic crossovers.

11 ndonuclease activity that resolves dHJs into crossovers.

12 ecombination, which can result in reciprocal crossovers.

13 conserved ubiquitin E3 ligase that regulates crossovers.

14 linked via the synaptonemal complex (SC) and crossovers.

15 s sufficient to more than double euchromatic crossovers.

16 gous chromosomes (homologs) pair and undergo crossovers; (2) homologs segregate to opposite poles; an

17 romosome 4, which normally never has meiotic crossovers [3].

18 Despite the allowance of crossover after disease progression, the OS benefit was

19 with varying magnetic concentration exhibits crossovers among the two glassy states and spin solid.

20 r) and cold season (October-April) in a case-crossover analysis using conditional logistic regression

21 Time-stratified case-crossover analysis was used with interaction terms for p

22 In the case-crossover analysis, a 1 degrees C increase during the we

23 In the case-crossover analysis, a 5 degrees F increase during the we

24 generalised linear mixed models and standard crossover analysis.

25 d to two alternative control weeks in a case-crossover analysis.

26 eals that HEI10 naturally limits Arabidopsis crossovers and has the potential to influence the respon

27 essfully overcomes large energy barriers via crossovers and mutations of pathways and finds all possi

28 dynamics give rise to surprising robustness crossovers and re-rankings, which can have significant i

29 ble strand breaks, which precede chromosomal crossovers and thus may be the point of origin for the M

30 etals, expensive separators, active material crossover, and corrosive and hazardous electrolytes.

31 ve severing of the "crossing" microtubule at crossovers, and reveals a hitherto not appreciated role

32 e of interference and the centromere effect, crossovers are distributed more uniformly along chromoso

33 When these crossovers are unanticipated, they appear to be the resu

34 centromere effect) and between chromosomes (crossover assurance) [2].

35 an extremely sharp or a comparatively smooth crossover between different regimes.

36 The skyrmions exhibit a smooth crossover between isolated (metastable) and disordered l

37 system under a bosonic reservoir during the crossover between Markovian and non-Markovian regimes.

38 Supported by cluster calculations, we find a crossover between surface and bulk in the electron hybri

39 Ruiz et al. find a crossover between these states in beta-Li2IrO3 under wea

40 The corresponding crossover between these two regimes in terms of the adva

41 Regulated distribution of crossovers between chromosome pairs is also lost, result

42 For this program, crossovers between homologous chromosomes play an essent

43 50 (77%) were enrolled (2343 long-term, 2207 crossover) between Aug 7, 2007, and June 20, 2008.

44 y blinded, randomized, 3-treatment, 6-period crossover bioequivalence study was conducted at the Univ

45 When a crossover by conversion was possible, only 14% of report

46 y for a systematic study of the BCS-BEC-like crossover by means of conventional condensed matter prob

47 ange in which the magnetic bistability (spin crossover) can be observed.

48 We performed a double-blind crossover challenge of 59 individuals on a self-institut

49 ulticenter, single-blind, placebo-controlled crossover clinical trial was conducted from December 19,

50 ents with type 2 diabetes (T2D).A randomized crossover clinical trial was conducted in patients with

51 etS; n = 10/group) completed a double-blind, crossover clinical trial with four 72-h interventions du

52 (DO) mouse stock accumulate large numbers of crossover (CO) events between founder haplotypes, and th

53 f pairing interactions and the completion of crossover (CO) formation between homologs during meiosis

54 spatial juxtaposition, with implications for crossover (CO) patterning/interference.

55 l chromosome segregation in meiosis requires crossover (CO) recombination, which is regulated to ensu

56 This retrospective study incorporated a crossover cohort study to identify triggers and a case-c

57 2626 women (1343 long-term; 1283 crossover) completed the extension.

58 The Fe(II) spin crossover complex [Fe{H2 B(pz)2 }2 (bipy)] (pz = pyrazol

59 long alkyl chains is reported as a rare spin-crossover compound displaying a wide thermal hysteresis

60 All variants underwent dimerization and crossover concurrently, and at wild-type rates.

61 s in atlastin to selectively destabilize the crossover conformation and used fluorescence-based kinet

62 ization between GTPase heads and a favorable crossover conformational shift, catalyzed by GTP hydroly

63 blood glucose concentration in 2 randomized, crossover, controlled studies (double-blinded for the su

64 An additional randomized, crossover, controlled study on 16 volunteers consuming c

65 subjects were recruited to this randomized, crossover, controlled trial.

66 We performed a randomized crossover-controlled exposure study to allergen and dies

67 During meiosis, the formation of crossovers (COs) generates genetic variation and provide

68 SBs) undergo recombinational repair, genetic crossovers (COs) may be formed.

69 ch promotes homologous pairing and generates crossovers (COs) to connect homologous chromosomes until

70 ested that selective severing at microtubule crossovers could facilitate the removal of discordant mi

71 g, were identified by QTL analyses using the crossover counts as a trait.

72 ecies regulate meiotic DSB formation to form crossovers crucial for meiosis.

73 After crossover, data were available for 22 itMSC patients.

74 l studies-3 with a randomized, double-masked crossover design and 1 with 4 parallel crossover studies

75 Case-crossover design and conditional logistic regression to

76 A double-blind, placebo-controlled, crossover design approach was used in abstinent alcohol

77 tACS was applied using a sham-controlled crossover design at individualized intensity for 20 min

78 in a 2-drug, double-blind placebo-controlled crossover design conducted from January 21, 2009, to Sep

79 aging in a double-blind, placebo-controlled, crossover design to determine how intranasally administe

80 on) + /- hydrocortisone (HC) in a randomised crossover design to produce low, medium and high glucoco

81 Our study used a crossover design to test to what extent insulin-induced

82 A single-blind randomized crossover design was used.

83 le-blind, placebo-controlled, within-subject crossover design we aimed to determine the effect of a s

84 nmol or 1150 mg) amounts of sodium for 30 d (crossover design).

85 ents to one of four treatment sequences in a crossover design, each involving two 16-week treatment p

86 The case-crossover design, introduced in 1991 by Malcolm Maclure,

87 In a double-blind placebo-controlled crossover design, the immune system in 22 sample donors

88 In a randomized, counterbalanced, crossover design, we applied anodal tDCS (atDCS), cathod

89 Using case-crossover design, we compared the following exposure sta

90 Using a case-crossover design, we examined the association of congest

91 In this open-label, multicenter trial with crossover design, we randomly assigned patients with new

92 Here, in a randomized, counterbalanced crossover design, we subjected participants to 3 weeks o

93 e occasions in a single-blind, random order, crossover design.

94 l meal and a strawberry meal in a randomized crossover design.

95 g asthmatics using an open-label, randomized crossover design.

96 4 separate days with the use of a randomized crossover design.

97 ects completed a randomized, double-blinded, crossover-design study in which they consumed either 5 o

98 hromosome axes and stable strand exchange of crossover-designated DSBs.

99 a model in which Polo-like kinases recognize crossover designation and phosphorylate SYP-4 thereby st

100 eaks (DSBs) via a feedback loop triggered by crossover designation in C. elegans.

101 ouble-strand break (DSB) formation following crossover designation, and ensuring accurate meiotic chr

102 phosphorylation depends on DSB formation and crossover designation, is required for stabilizing the S

103 The fine-scale accuracy of crossover detection was validated by Sanger sequencing f

104 , certain variants were unstable once in the crossover dimer conformation, and crossover dimer stabil

105 nce in the crossover dimer conformation, and crossover dimer stability closely paralleled lipid-mixin

106 act as a conduit to regulate chromosome-wide crossover distribution.

107 the present study consists of a randomized, crossover, double-blind, placebo-controlled laboratory s

108 was investigated in the present randomized, crossover, double-blind, placebo-controlled, human labor

109 Li3 site at higher Li contents (stage 1b), a crossover driven by the different signs of the local vol

110 The proper distribution of crossovers during meiosis I ensures accurate chromosome

111 The double crossover (DX) design motif has demonstrated versatility

112 lattices and tubular assemblies from double crossover (DX) tiles, a canonical motif in DNA nanotechn

113 prime importance of disorder in dimensional crossover effects.

114 Crossovers even occur on the small chromosome 4, which n

115 However, crossover events are relatively rare, typically one to t

116 d on recombination from an estimated 126,300 crossover events over the whole NAM panel.

117 ted by Sanger sequencing for a subset of ten crossover events.

118 glion cell types, raising the possibility of crossover excitation in violation of the canonical ON-OF

119 Crossover experiments have probed the reversibility of e

120 oselectivity and differing results in (13)CN crossover experiments, initial rate kinetics, and natura

121 recapitulate the dynamic localization of pro-crossover factors during meiotic progression, revealing

122 emarkably, our magnetization curves reveal a crossover field [Formula: see text], where we propose th

123 an initial >457 basepair (bp) HSV-1 x HSV-2 crossover followed by back-recombination to HSV-2.

124 active DBS or sham for 3 months, followed by crossover for another 3-month period.

125 However, whether crossover formation actually energizes fusion remains un

126 In most sexually reproducing organisms, crossover formation between homologous chromosomes is ne

127 We present a detailed study of crossover formation in human male and female meiosis, en

128 hind genes and open chromatin for predicting crossover formation over 10-kb windows.

129 ys important roles in promoting interhomolog crossover formation, regulating cessation of DNA double-

130 tract lengths genome-wide, without affecting crossover formation.

131 The differences observed in the crossover frequencies corresponding to pKa differences i

132 revisiae, each strategy is able to stimulate crossover frequencies in naturally recombination-cold re

133 Despite these critical functions, crossover frequency varies extensively within and betwee

134 nds to an unprecedented 7.8-fold increase in crossover frequency.

135 C bond formation (i.e., "LUMO umpolung") and crossover from a diradical to a zwitterionic mechanism t

136 sing pressure, indicating a pressure-induced crossover from a localized 4f (13) state to the valence

137 sive coronary angiography have high rates of crossover from control to intervention groups and do not

138 012, the study protocol was amended to allow crossover from control to trastuzumab emtansine after th

139 dihedral angles unequivocally support that a crossover from delocalization to hopping occurs at a uni

140 re of the spinel CoV2O4, which stands at the crossover from insulating to itinerant behavior using th

141 r density in Cd3As2 nanoplates, we observe a crossover from multiple-frequency to single-frequency Sh

142 The crossover from phonon-, to charged-impurity, limited con

143 rve diffusive atomic transport, signalling a crossover from quantum to classical expansion dynamics.

144 o allow patients with disease progression to crossover from treatment of physician's choice to trastu

145 ts reinforce this biphasic model, in which a crossover from uniform lateral growth to localized septa

146 e character of the pairing is conjectured to crossover from weak (BCS-like) to strong coupling (BEC-l

147 This is accompanied by a crossover from weak- to strong-coupling superconductivit

148 ay be a promising catalyst in self-hydrating crossover gases while retarding desorption of and captur

149 al coding sequence, with a corresponding non-crossover gene conversion rate of 8.75 +/- 0.05 x 10(-6)

150 transitioned to denosumab in the extension (crossover group).

151 in the long-term group and six cases in the crossover group.

152 state at room temperature, manifesting spin-crossover in solution at low temperatures, whereas corre

153 ses through the minimum that marks the 3D-2D crossover in the system.

154 explains the anomalies and fragile-to-strong crossover in water.

155 l repertoire by changing the distribution of crossovers in a wide range of eukaryotes.

156 But when we can predict crossovers in advance, they offer opportunities to strat

157 s identified three pathways limiting meiotic crossovers in Arabidopsis thaliana that rely on the acti

158 llectively, our results suggest that meiotic crossovers in potato are largely determined by the local

159 The strongest HEI10-mediated crossover increases occur in subtelomeric euchromatin, w

160 lly explained by the theoretically predicted crossover into a spin-frozen state.

161 e present in the other ring, both direct and crossover intramolecular cation-nucleophile reactions oc

162 epair intermediate is designated to become a crossover is a highly regulated decision that integrates

163 Here we show that active-species crossover is arrested by scaling the membrane's pore siz

164 This crossover is destroyed by an applied magnetic field whic

165 The doublet-to-quartet spin crossover is significantly faster than the oscillation p

166 The increase in crossovers is not uniform along chromosomes and rises fr

167 isk of high LDL cholesterol.In a randomized, crossover, isocaloric, controlled-feeding study, 51 men

168 suggesting that gene conversion and unequal crossovers lead to repeat homogenization through concert

169 Additionally, crossover levels on different chromosomes in the same nu

170 diets, each for a 4-wk period according to a crossover low fat (60% carbohydrate, 20% fat, 20% protei

171 guidewires were most suitable for the iliac crossover maneuver.

172 Further, this "female-specific crossover maturation inefficiency" is inferred to make m

173 Crossovers mediate homolog segregation and arise from se

174 Case-crossover models confirmed this inverse association over

175 Double-blind, randomized, crossover noninferiority trial involving 501 adults with

176 Prospective, crossover, nonrandomized interventional study.

177 gly agree with expected allele frequency and crossover number.

178 hly variable between meioses, although total crossover numbers are tightly regulated.

179 strand break repair, chromosome synapsis and crossover numbers.

180 This corresponds to an absolute rate of RAO crossover of less than 3 mumol cm(-2) day(-1) (for a 1.0

181 2 are the major products of the biosynthetic crossover of the 5-lipoxygenase (5-LOX) and cyclooxygena

182 n somatic cells leading to an obligatory non-crossover outcome, thus avoiding the potential for chrom

183 In the major interference-responsive crossover pathway in baker's yeast, these breaks are res

184 Here we review the major crossover pathways in plants and some of the known homeo

185 difficult to assess the relationship between crossover patterning and meiotic chromosome behavior.

186 Because the mechanisms that generate crossover patterning have remained elusive for over a ce

187 dy reveals both the consequences of improper crossover patterning in Drosophila and the role of Blm h

188 We show here that meiotic crossover patterning is lost in Drosophila melanogaster

189 y regulated decision that integrates several crossover patterning processes, both along chromosome ar

190 andomized, double-blind, placebo-controlled, crossover pilot study of REP supplementation (5 g/day x

191 in 6 patients in an open-label, randomized, crossover pilot trial (EudraCT 2012-004004-36), and rela

192 mmation in a single-blind placebo-controlled crossover pilot trial.

193 ose cohorts underwent a further double-blind crossover, placebo-controlled oral gluten challenge, whi

194 with a simple block method to a double-blind crossover, placebo-controlled oral gluten challenge.

195 of the intermediates that should mature into crossover products actually fail to do so.

196 th Epilepsy (EQUIGEN) single-dose study is a crossover, prospective, sequence-randomized, replicate p

197 Open-label crossover randomized clinical trial conducted in 15 diab

198 rdiometabolic risk factors.In a multicenter, crossover, randomized controlled trial, 92 men and women

199 This was a single-blind, placebo-controlled, crossover, randomized phase II-a trial of nonischemic ca

200 fication and preservation of arm lymphatics, crossover rates, blue node metastases, axillary recurren

201 Although natural crossover recombination modifier loci have been detected

202 ring meiosis, homologous chromosomes undergo crossover recombination, which creates genetic diversity

203 SMC)-an approximation of the coalescent with crossover recombination.

204 , two E3 ligases that are also essential for crossover recombination.

205 We demonstrate that crossovers reside in genomic regions of "open chromatin"

206 are necessary for both hot spot activity and crossover resolution.

207 The spin crossover (SCO) phenomenon defines an elegant class of s

208 atures (T1/2) in CDCl3 solution of five spin-crossover (SCO)-active [Fe(II)(L(azine))2(NCBH3)2] compl

209 rrous [Fe2 L3 ](4+) helicate exhibiting spin crossover (SCO).

210 h of sustained wakefulness during 3 balanced crossover segments, once under dim light (DL: 8 lx), and

211 wo consecutive 14-day treatment periods in a crossover sequence.

212 LA had higher viscosity and there was also a crossover shift to lower strains in the G'-G'' curve of

213 Meiotic crossovers shuffle parental genetic information, providi

214 resence of competing boronic acids showed no crossover side-products and confirmed the stability and

215 n establishes a precondition for designating crossover sites via selective protein stabilization.

216 9), randomized clinical trials (n = 9), and crossover studies (n = 5).

217 asked crossover design and 1 with 4 parallel crossover studies.

218 This double-blind, randomized crossover study addressed the impact of daily stressors

219 pen-label, expanded safety and acceptability crossover study comparing rectally applied reduced-glyce

220 A case-crossover study design was used to investigate associati

221 ing a prospective, randomized, single-blind, crossover study design, we therefore measured EE and rat

222 eve catecholamine depletion in a randomized, crossover study design.

223 ts and ER visits for GI illness using a case-crossover study design.

224 randomized, double-blind, placebo-controlled crossover study design.

225 double-blind, randomized, placebo-controlled crossover study evaluating the effect of 14 days of XEN-

226 This was a prospective randomized crossover study in nonintubated patients with AHRF with

227 A 5-year natural experimental crossover study involving patients admitted to four ICUs

228 llen Children and Adolescent study is a case-crossover study of 644 children and adolescents (aged 2-

229 ble-blinded, randomized, placebo-controlled, crossover study of DBS targeting the ventral striatum/an

230 randomized, double-blind, placebo-controlled crossover study of individuals with self-reported non-ce

231 his was a randomized, double-blind, 12-week, crossover study of rosuvastatin 20 mg versus placebo, fo

232 A case-crossover study of Swedish cases was conducted to ascert

233 completed a double-blind, placebo-controlled crossover study of the effects of a single dose of amphe

234 lled in a double-blinded, placebo-controlled crossover study to assess the effect of 1200 mg of gamma

235 Subsequently, a crossover study was performed by randomly assigning anot

236 randomized, double-blind, placebo-controlled crossover study with single-dose intranasal oxytocin (24

237 In our human crossover study, 11 healthy subjects were studied under

238 genous pathway.In a randomized, double-blind crossover study, 16 healthy individuals were supplemente

239 In an open-label randomized crossover study, 19 healthy firefighters (age, 41+/-7 ye

240 In the crossover study, 31 healthy volunteers completed two ran

241 In the crossover study, mean removal rate was 94.6% (SD = 6.5%)

242 In conclusion, in this randomized, crossover study, there was no significant difference in

243 In this randomized, double-blind, crossover study, twelve normoglycaemic men (BMI 25-35 kg

244 In this open-label, randomised, crossover study, we recruited adults (aged >/=18 years)

245 In this randomised, crossover study, we recruited men and women aged 60 year

246 corrected, double-blind, placebo-controlled, crossover study.

247 IU) or placebo in a double-blind, randomized crossover study.

248 abetes in a randomized, single-blind, triple-crossover study.

249 alignancies in the placebo group were in the crossover subgroup.

250 iochemical mechanism for the role of Srs2 in crossover suppression by promoting SDSA through disrupti

251 des temperatures well above the thermal spin crossover temperature of 160 K.

252 ear multisite randomized clinical trial with crossover that took place in 65 cardiac units in 17 hosp

253 dropout rate before treatment, which led to crossover therapy in the ICC group, and by an increased

254 Long-range ordering of DNA crossover tiles with blunt ends on lipid bilayers is inv

255 st participants underwent a third scan after crossover to 12-14 weeks of CBT.

256 Formula: see text] in a Fermi liquid and the crossover to [Formula: see text] in quantum critical reg

257 e (DeltaS M) to accurately map the nonlinear crossover to the chiral soliton lattice regime from the

258 prazolam (double-blinded, placebo-controlled crossover) to determine whether the cortical effects of

259 ings, supported by theory, show how the spin crossover transition can be manipulated reversibly aroun

260 The spin-crossover transition states are thoroughly investigated,

261 om temperature; that is, well above the spin crossover transition temperature for the pristine powder

262 wo changes in spin state and, thus, two spin-crossover transitions.

263 ng electron transfer, followed by direct and crossover trapping of the benzylic cations by the ortho-

264 static breast cancer even in the presence of crossover treatment.

265 ouble-blind, randomised, placebo-controlled, crossover trial (ReBUILD) in patients with relapsing mul

266 This was a cluster-randomized, multiple-crossover trial among 974 adults admitted to a tertiary

267 le-blind, placebo-controlled, single-centre, crossover trial assessed the effectiveness of an oral ne

268 We did a pragmatic, cluster-randomised, crossover trial at nine hospitals in the southeastern US

269 A quasi-experimental, crossover trial comparing PPA and PPRF for adult inpatie

270 ecord-embedded, cluster-randomized, multiple-crossover trial comparing saline with balanced crystallo

271 andomized, double-blind, placebo-controlled, crossover trial evaluating the pharmacodynamic effects o

272 A phase 2 randomized, placebo-controlled, crossover trial found that the GABA-B agonist arbaclofen

273 double-blind, randomized, placebo-controlled crossover trial in 18 adults with DSM-5 SAD and compared

274 ouble-blind, randomised, placebo-controlled, crossover trial in two UK medical centres.

275 Our original study was a crossover trial including 19 otherwise healthy smokers w

276 Randomized, double-blind, treat-to-target crossover trial including two 32-week treatment periods,

277 Nonrandomized crossover trial involving 6 healthy adults who were trea

278 andomized, double-blind, placebo-controlled, crossover trial of 3 QT-prolonging drugs with 15 time-ma

279 andomised, placebo-controlled, double-blind, crossover trial of a quadpill-a single capsule containin

280 , double-blind, placebo-controlled, phase 3, crossover trial to evaluate the efficacy and safety of i

281 To pilot a cluster-randomized, multiple-crossover trial using software tools within the electron

282 This open-label, cluster, crossover trial was done in two Ghanaian non-tertiary ho

283 mmatory responses.In a randomized controlled crossover trial, 17 participants [body mass index (in kg

284 nter, randomized, placebo (PLAC)-controlled, crossover trial, 45 patients with nondiabetic CKD stages

285 In a randomized crossover trial, patients with type 1 diabetes and norma

286 In this randomised, controlled, crossover trial, we recruited healthy volunteers (aged 2

287 andomized, double-masked, placebo-controlled crossover trial.

288 tes during exercise recovery in young men.In crossover trials, 10 resistance-trained men [aged 21 +/-

289 develop a theory of the ballistic-to-viscous crossover using an approach based on quasi-hydrodynamic

290 ogap phenomena throughout the entire BCS-BEC crossover, using a pairing fluctuation theory.

291 ive trait loci (rQTLs) that explain 56.9% of crossover variation in ColxLer F2 populations.

292 lymer membranes, the rate of active-material crossover was reduced more than 9000-fold compared to tr

293 The vast majority (81%) of meiotic crossovers were mapped to less than 5 kb.

294 The genomic regions spanning crossovers were significantly enriched with the Stowaway

295 frequency of homologs that do not receive a crossover, which in turn leads to elevated nondisjunctio

296 by endonuclease activity to form exclusively crossovers, which are critical for proper homolog segreg

297 uorine atoms in [Fe(dftpy)2](2+) enable spin crossover with a T1/2 of 220 K and a mixture of low-spin

298 e randomly assigned to a blinded 4-treatment crossover, with each treatment of single-day duration.

299 double-strand breaks (DSBs) are repaired as crossovers, with the remainder becoming noncrossovers [1

300 A pressure-induced anomalous valence crossover without structural phase transition is observe