ライフサイエンスコーパス: crotonase

1 use homologues of both Glu144 and Glu164 in crotonase.

2 id/base catalysis in a second family member, crotonase.

3 applicable to other related enzymes such as crotonase.

4 ce of the crt gene indicates that it encodes crotonase, a protein with 261 amino acid residues and a

5 Enzyme activity assays showed that crotonase and BHBD were highly overproduced in cell extr

6 erized members of the crotonase superfamily (crotonase and dienoyl CoA isomerase), MMCD is a hexamer

7 oted a betabetaalpha-spiral fold shared with crotonases and C-terminal protein transferases.

8 f coenzyme A-independent activity within the crotonases and provide further evidence of a wider supra

9 amate residues in the reactions catalyzed by crotonases and the eukaryotic MGCHs.

10 tonase family including enoyl-CoA hydratase (crotonase) and methylmalonyl-CoA decarboxylase.

11 tyryl-coenzyme A (CoA) dehydrogenase (BHBD), crotonase, and butyryl-CoA dehydrogenase (BCD) from Clos

12 lu164 but not of Glu144 in rat mitochondrial crotonase are encoded by operons of which the functions

13 ive-site residue contrasts with the paradigm crotonases as well as with the recently identified mamma

14 Clustered genes encoding BHBD, crotonase, BCD, and putative electron transfer flavoprot

15 the subclone, the activities of the enzymes crotonase, BHBD, and BCD were elevated.

16 comprises two domains, both belonging to the crotonase/ClpP superfamily.

17 d hbd and also in a gene predicted to encode crotonase (croA), which is involved in fatty acid degrad

18 ), 3-hydroxybutyryl-CoA dehydrogenase (Hbd), crotonase (Crt), and trans-enoyl-CoA reductase (Ter) fro

19 coli genome encodes seven paralogues of the crotonase (enoyl CoA hydratase) superfamily.

20 splays sequence homology with members of the crotonase family including enoyl-CoA hydratase (crotonas

21 n a trimeric form as do other members of the crotonase family.

22 prafamily of enzymes that have recruited the crotonase fold for the catalysis of reactions other than

23 that methylmalonyl-CoA mutase, an R-specific crotonase, isobutyryl-CoA dehydrogenase, and a GTPase ar

24 12S domains are structurally similar to the crotonase/isomerase superfamily, although only domain 1

25 eral acid/base Glu 144 in the active site of crotonase, its carboxylate side chain is hydrogen bonded

26 anobacterium Anabaena sp. PCC 7120 encodes a crotonase orthologue that displays beta-diketone hydrola

27 id dehalogenase, enolase, amidohydrolase and crotonase superfamilies and to the serine proteases.

28 er structurally characterized members of the crotonase superfamily (crotonase and dienoyl CoA isomera

29 sults reveal the potential of the ubiquitous crotonase superfamily as adaptable catalysts for the con

30 yl]acetic acid, a reaction unusual among the crotonase superfamily as the substrate is not an acyl-Co

31 bstrates has not been reported for any other crotonase superfamily decarboxylase.

32 xylase (MMCD), a newly defined member of the crotonase superfamily encoded by the Escherichia coli ge

33 The results demonstrate the utility of the crotonase superfamily enzymes for stereoselective biocat

34 (2) domain establishes that the protein is a crotonase superfamily member.

35 t 2-ketochc-CoA hydrolase is a member of the crotonase superfamily of proteins.

36 as a particularly interesting member of the crotonase superfamily that combines in one net reaction

37 rboxymethylproline synthases, members of the crotonase superfamily, aimed at enabling stereoselective

38 erase activities are known activities of the crotonase superfamily, Bcam0581 is the first protein sho

39 CarB, a member of the crotonase superfamily, catalyzes the formation of (2S,5S

40 Unlike the other members of the crotonase superfamily, however, the C-terminal motif is

41 Like other members of the crotonase superfamily, MenB folds as an (alpha3)2 hexame

42 d enoyl-Coa isomerase, both belonging to the crotonase superfamily.

43 nge of reactions catalyzed by members of the crotonase superfamily.

44 Members of the enoyl-CoA hydratase (crotonase) superfamily catalyze different overall reacti

45 Bcam0581 is annotated as a homologue of crotonase, the first enzyme of the fatty acid degradatio

46 the enolase, amidohydrolase, thiyl radical, crotonase, vicinal-oxygen-chelate, and Fe-dependent oxid