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1                                              Crucially, a single dose of 10-del ZIKV induced steriliz
2                                              Crucially, a test of this hypothesis requires the within
3                                              Crucially, a treatment with NPs prior to infection provi
4                                              Crucially, abolishing cell cycle asynchrony consistently
5 tude larger than that of the null model, and crucially, above the critical threshold for the formatio
6                                              Crucially, activity at local nodes within the modules do
7                                              Crucially, administration of the dopamine prodrug, levod
8         The quantum nature of the proton can crucially affect the structural and physical properties
9  axon, tau's MT binding and localization are crucially affected by the presence of the PRR and tau hy
10 ic interplay between Wnt and Notch signaling crucially affects hepatocyte regeneration in the fibroti
11  number of available workers to the workload crucially affects performance.
12 nce of an attractive quantum potential which crucially affects the dynamics in matter-wave circuits.
13 k in tasks they are not currently engaged in crucially affects whether task allocation is quickly ach
14                                              Crucially, all seven processes occurred in the same temp
15 akened some measures of sexual selection and crucially also impacted sexual selection indirectly by c
16 n of their respective molecular targets, but crucially also revealed system-wide neural circuit respo
17 rozoite egress and erythrocyte invasion, but crucially, also blocks transmission of mature P. falcipa
18                                              Crucially, although there are many advantages to this ap
19  show that the mobility of DNA knots depends crucially and subtly on the physical properties of the g
20 des in the endosomal-like compartment and is crucially associated to rhoptry discharge during invasio
21 e of return from investment and secondly and crucially because national research assessments are beco
22 physics, where control over interactions has crucially been afforded by tunable Feshbach resonances.
23                                              Crucially, behavioral measures of mathematics, IQ, worki
24                                              Crucially, both examples avoid all six of the potential
25                                              Crucially, both the standard Greenland and the merged Gr
26                                              Crucially, by employing functional tagged proteins, our
27                                              Crucially, carnosine also reverses glucolipotoxic inhibi
28                                              Crucially, CENP-A with acetylation-mimetic H4 was assemb
29 ctivity, to preserve the asynchronous state, crucially changes the characteristics of the emergent re
30                                              Crucially, children with greater tutoring-induced decrea
31             Syntaxins are target-SNAREs that crucially contribute to determine membrane compartment i
32 led analyses revealed that thymic Treg cells crucially contribute to the effectiveness of IT by promo
33  nymph to adult should be taking place, thus crucially contributing to the correct culmination of met
34 d, toxin-intrinsic thiol rearrangements that crucially control toxin conformation and host cell killi
35                                              Crucially, cross-prediction showed that mean reward and
36                                              Crucially, data-driven neural simulations revealed a cle
37  model explains the dual role of c-FLIPL and crucially defines how c-FLIP isoforms differentially con
38 , Ln-doping (400 ppm) of the alumina lattice crucially delays the onset of phase transformation and e
39 ns emerge from early retinotopic cortex, and crucially demonstrates that retinotopically tuned region
40              Their disaggregation activities crucially depend on partner proteins, which target the A
41 gnetic properties of these materials seem to crucially depend on whether the magnetizations of the R
42  Sediment fluxes in aquatic environments are crucially dependent on bedform dynamics.
43                     Although Ewing cells are crucially dependent on continuous expression of EWS-FLI1
44  assessment of environmental contaminants is crucially dependent on the predictability of the trophic
45 larity distributions and alignment, which is crucially dependent on the rate of actin filament turnov
46 h spontaneous breaking of chiral symmetry is crucially dependent on the shape of molecular dimers, wh
47 t that a rapid response in usher assembly is crucially dependent on the translocation assembly module
48  demonstrate that centriole amplification is crucially dependent on these organizing centres and that
49 plate in methylcellulose culture, a property crucially dependent upon ABCC4.
50   Identifying differentially expressed genes crucially depends on estimates of read-count variability
51                      Oxygenic photosynthesis crucially depends on proteins that possess Fe(2+) or Fe/
52  phenomena in physics, biology and economics crucially depends on the analysis of multivariate time s
53 ts folding landscape, but also in many cases crucially depends on the details of the folding pathways
54               The feasibility of elimination crucially depends on the effects of multiple ivermectin
55      High-resolution structure determination crucially depends on the homogeneity of the protein crys
56                          Sexual reproduction crucially depends on the production of sperm in males an
57                                              Crucially, despite the largely separate spatial extend o
58 ithin the globular domain of histone H4 that crucially determine genome organization and expression i
59 pools to globally rising surface temperature crucially determines the feedback between climate change
60                                              Crucially, diabetes represses transcription of the key m
61 oscillation was faster than that in CA3 and, crucially, did not appear to require the involvement of
62                                              Crucially, different demographic rates responded in oppo
63                              The latter also crucially directs the molecular packing in the solid.
64 in during awake and anesthetized states and, crucially, during the transition is not clearly understo
65                                              Crucially, dynamical response measurements above interla
66  of magnitude of agonist concentration, thus crucially enhancing the collective bandwidth of endothel
67 ng to the cellular trafficking apparatus, it crucially ensured temporal and spatial accuracy in deter
68 with the execution of voluntary action, and, crucially, even for visual stimuli irrelevant to the mot
69 es sentences, represents their meaning, and, crucially, exhibits oscillatory activation patterns rese
70 mplate type, master mixes, primer pairs and, crucially, extraction methods on dPCR performance.
71                                              Crucially, forgetting of no-go cues was predicted by hig
72                                              Crucially, gamma tACS induced motor performance enhancem
73 n was considered "best practice." This study crucially highlights that surgeons must develop better c
74                                              Crucially, HIV-1 mutants containing segments whose CG co
75                                              Crucially however, our bifurcation analysis reveals that
76                                              Crucially, however, it correlates to the period within t
77                                              Crucially, however, the anterior prefrontal cortex lesio
78 h mechanisms based on the recurrent feedback crucially ignore the contribution of feedforward input t
79 up via aza-Michael addition/elimination, and crucially (iii) facile access to basidalin by late-stage
80 rks of type-II phase oscillators and, hence, crucially impacts on the overall hierarchical connectivi
81 iogenic amine and to specific alterations of crucially important 5-HT-dependent neurogenic processes.
82 ic turnover of integrins in a manner that is crucially important for angiogenesis in vitro and in viv
83                        Young researchers are crucially important for basic science as they make unexp
84               Surfaces of semiconductors are crucially important for electronics, especially when the
85 ts of the green fluorescent protein (GFP) is crucially important for imaging live cells, tissues and
86                   Involuntary migration is a crucially important global challenge from an economic, s
87 ase transitions in reactive environments are crucially important in energy and information storage, c
88                                 This will be crucially important in our attempts to track and control
89 nectivity mapping process, gene signature is crucially important in returning biologically meaningful
90 formed at the interface whose properties are crucially important in samples with a thickness of YIG l
91 sults suggest that Eunotosaurus represents a crucially important link in a chain that will eventually
92  culture and phylogeny will continue to have crucially important roles in human microbiota research,
93 on of bacterial genomes is an obligatory and crucially important step of information processing from
94 horough review of the existing literature is crucially important to drive new research.
95                                    It is now crucially important to translate this knowledge into rea
96          Slow-release (SR) drug delivery can crucially improve efficacy and safety of rapidly absorbe
97         The trials showed that the DNA prime crucially improved the responses, and three DNA primes w
98 eing an issue in the long term for all, more crucially in smaller children.
99                                              Crucially, in a brain region thought to be responsible f
100                                              Crucially, in both demonstration conditions some childre
101                                              Crucially, in dilute solution of these systems, SF does
102                                              Crucially, in the activated endothelial (HMEC-1) cell as
103                                              Crucially, inactivation of rsp preserves bacterial disse
104                                              Crucially, increased SN/VTA and ventral striatal adaptat
105 inity through reducing root-soil contact and crucially increasing porosity at the root-soil interface
106               Such NA-mediated costimulation crucially induces Th2 differentiation by suppressing T-b
107 controlled neo-glycosylation of antigens can crucially influence intracellular routing of antigens, t
108  that fate determination of cIN subgroups is crucially influenced by Shh signaling, and provide a sys
109 cally removed from around the target protein crucially influences LO decisions.
110                        The Rho GTPase Rac is crucially involved in controlling multiple B cell functi
111     Fibrin clot structure and clot lysis are crucially involved in development of cardiovascular even
112 naling pathway, mediated by beta-catenin, is crucially involved in development, adult stem cell tissu
113     We show that the stalk region of CD23 is crucially involved in IgE binding and that the interacti
114  gives rise to the above-ground tissues, are crucially involved in regulating differentiation.
115 permutation in the other CDRs of PGT145 were crucially involved in stabilizing the structure of the H
116 TPase Cdc48 and the Hsp70 chaperone Ssa1 are crucially involved in the elimination of Fas2.
117 1 (INI1) are tumor suppressor genes that are crucially involved in the formation of malignant rhabdoi
118 n particular, caspase-8 has been shown to be crucially involved in the induction of pro-IL-1beta synt
119 inity receptor for IgE, FcepsilonRI, and are crucially involved in the pathogenesis of AD by inducing
120 ng implicit attitudes about violence and are crucially involved in the pathogenesis of aggressive beh
121 at has been widely investigated as an enzyme crucially involved in the pathogenesis of chronic compli
122 increasing evidence that sleep disruption is crucially involved in the progression of Alzheimer's dis
123 lglycerol in the hippocampus, a brain region crucially involved in the regulation of memory processes
124           Cell adhesion molecules (CAMs) are crucially involved in these processes.
125 tem, such as cytokines or inflammasomes, are crucially involved.
126 s a firmly closed conformation of dimers and crucially involves the D4 domain, was observed with high
127 (Asl) is irreversible, requires DSas-4, and, crucially, is essential for daughter centrioles to matur
128 graphic locations has been demonstrated, but crucially it has not been shown whether this correlates
129                                         Yet, crucially, its longer-term history and links with Europe
130 s on carbon dynamics of tropical forests are crucially lacking.
131  nucleosomes into higher-order assemblies is crucially linked to nuclear processes.
132 on model and establishes that gingipains are crucially linked to systemic disease and potentially con
133 ic tissue context, and these metabolites are crucially linked to tissue-resident macrophage functions
134                                     However, crucially, loss-of-function experiments have not been re
135 on intensity, the photobleaching yield, and, crucially, management of bright/dark state transitions,
136                                              Crucially, memory benefitted from reinstatement when the
137                                              Crucially, metacognitive skills enable us to adjust ongo
138 anner, a phenomenon we term "minority MOMP." Crucially, minority MOMP leads to limited caspase activa
139                                              Crucially, misregulation of these processes may have pro
140 able tissues give rise to arrhythmias, it is crucially necessary to understand the electrical dynamic
141                                New drugs are crucially needed for children with cancer.
142 expensive catalysts for oxygen reduction are crucially needed for the widespread development of polym
143 ction of primary data for neonatal herpes is crucially needed to reduce uncertainty and refine future
144                                              Crucially, neither drug influenced the physical percepti
145                                              Crucially, neither species strictly specializes on eithe
146                                              Crucially, network and personality features interacted t
147                                              Crucially, normal NOS function depends on availability o
148                                              Crucially, numbers have gained importance for humans too
149 The control of DNA-mediated assembly depends crucially on a better understanding of three-dimensional
150 ocampus, the conduction speed of APs depends crucially on axon diameters, which vary widely.
151         Structural molecular biology depends crucially on computational techniques that compare prote
152                   Since new research depends crucially on existing knowledge, technology for semantic
153       Unlike previous explanations that rely crucially on heterogeneity, our results hold even for ho
154                     Bacterial growth depends crucially on metabolic fluxes, which are limited by the
155               Although degranulation depends crucially on microtubule dynamics, the molecular machine
156 pain-like responses in animal models depends crucially on our ability to quantitatively and objective
157 lf-compressed soliton, a process that relies crucially on phase-matching.
158 t unlike NMDAR-dependent plasticity, depends crucially on protein synthesis controlled by fragile X m
159 of ultrasociality in ants and humans depends crucially on recognizing differences as well as similari
160   In contrast, the axisymmetric flows depend crucially on the choice of boundary condition, in both t
161                         RNA function depends crucially on the details of its dynamics.
162 gy and motility of these spirochetes depends crucially on the flagellar/cell wall stiffness ratio.
163 es of structures whose functionality depends crucially on the length and time-scales at which spin-in
164 udies that activation and regulation depends crucially on the lipid composition of the surrounding me
165 citons whose photophysical properties depend crucially on the mutual arrangement of the pigments.
166 ponse screening of cancer cell lines depends crucially on the reproducibility of results.
167 demonstrate that assembly and budding depend crucially on the system dynamics via multiple timescales
168 y breadth development, in a way that depends crucially on the temporal pattern of immunization (or se
169 ormation among individuals, which may depend crucially on the underlying structure of the communicati
170 neration storage materials therefore depends crucially on understanding the correlation between the s
171                           The results depend crucially on whether the crystal symmetry is symmorphic.
172         Rich scenarios are found that depend crucially on whether the swimmer is a pusher or a puller
173                                              Crucially, one mutant viral clone with the five consensu
174 racks the presence of objects in scenes, but crucially only for those objects that were immediately r
175                                              Crucially, our analysis indicates that the performance o
176                                              Crucially, our computational analysis showed that this e
177                                              Crucially, our method performs well for short sequence f
178                                              Crucially, our study revealed the inhibitory modulation
179                                              Crucially, participants reported no conscious experience
180                 The therapeutic activity was crucially performed by CD8 T cells, as found in selectiv
181 litic nature of each family member, although crucially, POMzites differ from zeolites in the modular
182                                              Crucially, PPC regions responding to a particular effect
183                                              Crucially, protein abundance in single cells can vary si
184                                     IL-6 may crucially regulate this process; however, the underlying
185 control of active Src and FAK levels, and so crucially regulates their cancer-associated biological o
186 adjacent droplets on solid substrates, which crucially relies on a combination of capillarity and bul
187               Here we show, however, that it crucially relies on the Nlrp3 inflammasome and interleuk
188 he conserved NK-2 homeobox gene ceh-24 to be crucially required for flipping.
189                       We show that CENP-M is crucially required for the assembly and stability of a t
190 ficient embryos, we demonstrate that Jak2 is crucially required for the function of the first HSCs, w
191 w that extracellular signalling pathways are crucially required for threat memory formation.
192                                              Crucially, resembling paclitaxel treatment, silencing of
193                                              Crucially, shugoshins undergo changes in their localizat
194                                              Crucially, significance is established at the level of d
195                                              Crucially, similar increases in dispersion within groups
196                                              Crucially, sister chromatid separation must be delayed u
197            There were many similarities but, crucially, some differences in biomarker levels (IL-1bet
198                                              Crucially, such "triplet-sensitized CO-release" occurred
199 icle as an "integrative memory structure" is crucially supported by processes of mental model constru
200          The metabolic connectivity analyses crucially supported the neuroprotective effect of biling
201                                              Crucially, task relevance modulated these spectral corre
202 e been applied to the psychedelic state and, crucially, that they have yielded values exceeding those
203                                              Crucially the 3-D soil pore network, imaged using X-ray
204 implanted cells within the lesion cavity and crucially the contribution of neural stem cells and endo
205                                              Crucially, the absence of either of these distinct Tr ce
206                                              Crucially, the authors assume the existence of discrete
207                                              Crucially, the CDR3-like loop formed an electrostaticall
208                                              Crucially, the classifier was trained and tested on disj
209                                              Crucially, the compartmentalization enabled the formatio
210                                              Crucially, the contribution of life history traits to su
211                                              Crucially, the crossed hand posture elicited enhanced ac
212                                              Crucially, the different objects were sequentially sampl
213                                              Crucially, the distribution of gene expression in many o
214                                              Crucially, the effect of 10 Hz flicker on task performan
215 ically homologous photoreceptors in lamprey: crucially, the efficient amplification of the effect of
216                                              Crucially, the gain-of-function mutations could be pharm
217 certainties, a minimal processing time, and, crucially, the intrinsic costs of gaze behavior.
218                                              Crucially, the ITO distributes thermal energy created by
219                                              Crucially, the lead peptide enters cells and is biologic
220                                              Crucially, the magnitude of this effect correlated with
221                                              Crucially, the method does not assume that the metadata
222                                              Crucially, the phase code reflected input differences, b
223                                              Crucially, the precise dynamics of frequencies and phase
224                                              Crucially, the receptors feature high sensitivity and se
225                                              Crucially, the reduced mitochondrial Ca(2+) uptake is mi
226                                              Crucially, the relation between an action and the emotio
227                                              Crucially, the salience effect modulates attention orien
228                                              Crucially, the sensitive points of the network are broad
229                                              Crucially, the SNP does not alter the spontaneous incide
230                                              Crucially, the STN and lateral PFC beta decrease was sig
231                                              Crucially, the structure of the entire spatio-temporal n
232                                              Crucially, the structure reveals that the two MACPF doma
233                                              Crucially, the target desirability was encoded in LIP at
234                                              Crucially, the temporal window for visuotactile integrat
235                                              Crucially, the TMS pulse was delivered when all the subj
236                                              Crucially, the type of oxidative cross-linking dramatica
237                                              Crucially, the Windows version allows users to analyse M
238                                              Crucially, there are conflicting reports on detecting HE
239                                              Crucially, these activations spared areas related to lan
240                                              Crucially, these electrodes show a marked improvement in
241                                              Crucially, these findings describe a mechanism by which
242                                              Crucially, these human LGE progenitors readily different
243                                              Crucially, these large fields also allow observation of
244                                              Crucially, these results also offer potential insights f
245                                              Crucially, these stress mediators and their actions exhi
246                                              Crucially, they also need to compete for the interpretat
247 nvestigate social dynamics across time, and, crucially, they rarely study social behavior under natur
248                                              Crucially this highlights how new drugs, introduced to c
249                                              Crucially this reduced surface expression did not cause
250                                              Crucially, this allows the prediction of optimal surgica
251                                              Crucially, this differentiation was irrespective of whet
252                                              Crucially, this effect depended on the spatiotopic confi
253                                              Crucially, this functionality will allow users of BCI-FE
254                                              Crucially, this highlights a direct connection between l
255                                              Crucially, this individual-level support, rather than cu
256                                              Crucially, this mode of proliferation is independent of
257  no assistance was given (experiment 1) and, crucially, this was the case even when choosing the pros
258                                              Crucially, three of these domains would be lost or disru
259                   These functions contribute crucially to feeding behaviour by unknown neural mechani
260  Instead, our data show that Arg contributes crucially to ligand sensitivity via a hydrogen bond netw
261  results suggest that T cells can contribute crucially to protection against heterotypic reinfection
262 m a specific interneuron subtype contributes crucially to the cell-specific and circuit-wide deficits
263 esearch are urgently needed to improve, and, crucially, to personalise management.
264          Failure, damage spread and recovery crucially underlie many spatially embedded networked sys
265 le prokaryotic sources, an issue that hinges crucially upon factors influencing phylogenetic inferenc
266 ovably efficient hit-and-run random walk and crucially uses a preprocessing step to round the anisotr
267 ment of functional estrogen receptors (ERs), crucially, via its interaction with heat shock proteins
268                                              Crucially we are able to quantify the change in free ene
269                                              Crucially we demonstrate that solutions of 1-4 in SO2, a
270                                              Crucially we evaluated the optimal bait size for large f
271                                              Crucially we have discovered two modes of SMAD2 binding.
272                                              Crucially we show that the children were not influenced
273                                              Crucially, we also observed pervasive adaptations to the
274                                              Crucially, we conclude that comets containing water enri
275                                              Crucially, we demonstrate that knockdown of nuclear-loca
276                                              Crucially, we demonstrate that Mst, but not Mgr, is requ
277                                         Most crucially, we demonstrate that N-alkylation activates th
278                                              Crucially, we demonstrated for a subset of these novel p
279                                              Crucially, we find increases in ongoing DMN activity aft
280                                              Crucially, we find that each active site of a transposas
281                                              Crucially, we find that it is necessary to include hapto
282                                              Crucially, we find that loss of Elk1 causes enhanced Itg
283                                              Crucially, we find that relative, rather than absolute,
284                                              Crucially, we find that the same "visual" areas respond
285                                              Crucially, we find that these occipital areas respond mo
286                                              Crucially, we find that this difference between mnemonic
287                                              Crucially, we found that global motion direction could b
288                                              Crucially, we found that this region does not respond to
289                                              Crucially, we found the NFA to be present in both hemisp
290                                              Crucially, we provide collections of TSSs derived from m
291                                              Crucially, we provide in vivo evidence that HLA-G acts a
292                                              Crucially, we show for the first time that MHC-II expres
293                                              Crucially, we show that KDM3A catalytic activity is requ
294                                              Crucially, we show that relying on selective integration
295                                              Crucially, we show that the accuracy of the reconstructe
296                                              Crucially, we varied the number of consecutive trials du
297                                              Crucially, when multiple objects are present in a scene
298                                              Crucially, when sensory comparison is no longer requeste
299 e benzophenone dryness indicator in THF) or, crucially, with allylic-CH and conjugated unsaturated gr
300                                              Crucially, WSX-1(-/-) mice displayed significantly enhan

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