ライフサイエンスコーパス: cryptopatch

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1 nt across the spectrum of SILT, including in cryptopatches.

2 During colitis, ILC3s mobilize from cryptopatches, a process that can be inhibited by blocki

3 an important question is whether T cells in cryptopatch aggregates are lineally related to IEL.

4 The precise role of cryptopatch aggregates in intestinal gammadelta+ T cell

5 The role of cryptopatch aggregates in the development of intestinal

6 that the frequency of in-frame junctions in cryptopatch aggregates was at a level consistent with po

7 at if gammadelta+ IEL derive from T cells in cryptopatch aggregates, then a clonal relationship would

8 of gammadelta+ IEL are related to T cells in cryptopatch aggregates.

9 ed for NKp46(+) ILCs, whereas LTi-like ILCs, cryptopatches and ILFs were partially dependent on Notch

10 /-) mice also lacked postnatally 'imprinted' cryptopatches and isolated lymphoid follicles (ILFs), bu

11 , TCR-gammadelta IELs were restored, as were cryptopatches and Peyer's patches.

12 ude the bronchus-associated lymphoid tissue, cryptopatches, and isolated lymphoid follicles.

13 in-frame joints was significantly reduced in cryptopatch cells isolated from TCR delta-deficient mice

14 ng that the enrichment of in-frame joints in cryptopatch cells must normally depend on expression of

15 V-J junctions present in gammadelta+ IEL and cryptopatch cells were encoded by identical nucleotide s

16 We purified IEL by FACS and cryptopatch cells were isolated from frozen sections of

17 as rearranged in gammadelta+ IEL and in CD3+ cryptopatch cells, but not in CD3- cryptopatch cells.

18 riable region 5 genes in gammadelta+ IEL and cryptopatch cells.

19 d in CD3+ cryptopatch cells, but not in CD3- cryptopatch cells.

20 ot identify a role for alpha(4) integrins in cryptopatch (CP) development; however, these studies dem

21 iously identified VCAM-1(+) stromal cells in cryptopatches (CP) and isolated lymphoid follicles (ILF)

22 Small intestinal cryptopatches (CP) are the major anatomic site for extra

23 of LTalpha and LTbetaR to the development of cryptopatches (CP), aggregates of T cell precursors in t

24 Dendritic cells (DCs) are components of cryptopatches (CPs) and ILFs and were therefore evaluate

25 isolated and aggregated lymphoid follicles, cryptopatches (CPs) and tertiary lymphoid tissue.

26 CCR6 is present on lymphocyte precursors in cryptopatches, expressed transiently during extrathymic

27 present in the intestine also enter and exit cryptopatches in a highly dynamic process.

28 e adult intestine, luminal microbiota induce cryptopatches to transform into isolated lymphoid follic

29 e-inducer (LTi) cells, and LTi-like cells in cryptopatches within the adult intestinal lamina propria

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