ライフサイエンスコーパス: cryptosporidiosis

1 assessment of the role of raw vegetables in cryptosporidiosis.

2 erface in an in vitro model of human biliary cryptosporidiosis.

3 cause, including toxoplasmosis, malaria, and cryptosporidiosis.

4 samples from the 1993 Milwaukee outbreak of cryptosporidiosis.

5 SP mRNA was associated with symptoms in cryptosporidiosis.

6 cular tool in epidemiologic studies of human cryptosporidiosis.

7 red to be the pathogen responsible for human cryptosporidiosis.

8 a are not key mediators of diarrhea in human cryptosporidiosis.

9 tes are crucial steps in the pathogenesis of cryptosporidiosis.

10 cific preventive or therapeutic measures for cryptosporidiosis.

11 provide optimal passive immunization against cryptosporidiosis.

12 t for passive or active immunization against cryptosporidiosis.

13 the importance of copathogens in symptomatic cryptosporidiosis.

14 for effective management of human and animal cryptosporidiosis.

15 pecies play protective roles in experimental cryptosporidiosis.

16 s are currently available for the control of cryptosporidiosis.

17 ith paromomycin and azithromycin for chronic cryptosporidiosis.

18 er IS reduction nor specific therapy against cryptosporidiosis.

19 f 43 age-matched controls with no history of cryptosporidiosis.

20 olangitis seen in AIDS patients with biliary cryptosporidiosis.

21 ild growth in the community than symptomatic cryptosporidiosis.

22 t for passive or active immunization against cryptosporidiosis.

23 ited to develop an in vitro model of biliary cryptosporidiosis.

24 ulations within ileal mucosae of calves with cryptosporidiosis.

25 ion was characterized with a bovine model of cryptosporidiosis.

26 mportant for resistance to and resolution of cryptosporidiosis.

27 nd response to therapeutic agents in biliary cryptosporidiosis.

28 actors, modes of transmission, and impact of cryptosporidiosis.

29 ion as a drug candidate for the treatment of cryptosporidiosis.

30 as a lead compound for drug development for cryptosporidiosis.

31 al efficacy evaluation in the calf model for cryptosporidiosis.

32 utic drug leads in an animal model for human cryptosporidiosis.

33 or the development of drugs for treatment of cryptosporidiosis.

34 m parasites infect intestinal cells, causing cryptosporidiosis.

35 isease burden was also seen in children with cryptosporidiosis.

36 diseases such as malaria, toxoplasmosis, and cryptosporidiosis.

37 seases including malaria, toxoplasmosis, and cryptosporidiosis.

38 sative agents of malaria, toxoplasmosis, and cryptosporidiosis.

39 gs may be an effective strategy for treating cryptosporidiosis.

40 ility of HIV-infected individuals to biliary cryptosporidiosis.

41 serve as potential therapeutics for treating cryptosporidiosis.

42 n ideal model for enteric infections such as cryptosporidiosis.

43 cation in interventional in vitro studies of cryptosporidiosis.

44 redominant allele associated with waterborne cryptosporidiosis.

45 or the treatment of symptoms associated with cryptosporidiosis.

46 val among AIDS patients with newly diagnosed cryptosporidiosis?

47 mal volunteers (median in AIDS patients with cryptosporidiosis, 508 pg/mg protein, compared to 111 pg

48 ated its expression and role during neonatal cryptosporidiosis, a worldwide protozoan enteric disease

49 er was not associated with a reduced risk of cryptosporidiosis (adjusted RR = 0.86; 95% CI, .60-1.23)

50 in the number of HIV-infected patients with cryptosporidiosis after the period of water contaminatio

51 This study documented a high burden of cryptosporidiosis among children in an endemic Indian sl

52 A total of 194 cases of cryptosporidiosis among HIV-infected patients were ident

53 To assess the risk factors for sporadic cryptosporidiosis among immunocompetent persons, a match

54 lving 282 persons with laboratory-identified cryptosporidiosis and 490 age-matched and geographically

55 (HIV)-positive patients newly diagnosed with cryptosporidiosis and all 3,564 patients with newly diag

56 with protection of Bangladeshi infants from cryptosporidiosis and amebiasis.

57 rable with appropriate antimicrobial agents; cryptosporidiosis and C. difficile infections may howeve

58 Cryptosporidiosis and giardiasis are major public health

59 s with AIDS with naturally occurring chronic cryptosporidiosis and healthy volunteers with mild crypt

60 nd 72 pg/mg protein in AIDS patients without cryptosporidiosis and in normal volunteers, respectively

61 uggesting that cross-species transmission of cryptosporidiosis and microsporidiosis is possible.

62 asis, and some new leads on the treatment of cryptosporidiosis and refractory giardiasis.

63 unsupplemented animals developed persistent cryptosporidiosis and shed high levels of oocysts in the

64 y widely used drugs fail in the treatment of cryptosporidiosis and suggest more promising targets.

65 Understanding the natural history of cryptosporidiosis and the correlates of protection are e

66 in the understanding of the pathogenesis of cryptosporidiosis and the diagnosis of amebiasis and gia

67 ighlights the importance of surveillance for cryptosporidiosis and the need for guidelines for the pr

68 The search for effective therapeutics for cryptosporidiosis and toxoplasmosis has led to the disco

69 important human diseases including malaria, cryptosporidiosis and toxoplasmosis.

70 culosis, chronic herpes simplex, and chronic cryptosporidiosis) and an increase occurred in recurrent

71 Patients with AIDS, chronic cryptosporidiosis, and < 100 CD4 cells/microL were treat

72 tions caused by enteric protozoa (amebiasis, cryptosporidiosis, and giardiasis), rotavirus, astroviru

73 tunistic infections (malaria, toxoplasmosis, cryptosporidiosis, and Pneumocystis carinii pneumonia).

74 ry diagnosis is required to confirm cases of cryptosporidiosis, and species and genotype determinatio

75 onsible for global scourges such as malaria, cryptosporidiosis, and toxoplasmosis.

76 is a consistent feature of human and animal cryptosporidiosis, and yet their contribution to the pat

77 in was shown to be ineffective treatment for cryptosporidiosis; and these parasitic diseases continue

78 Most human cases of cryptosporidiosis are associated with C. hominis and C.

79 r mechanisms involved in the pathogenesis of cryptosporidiosis are unknown.

80 lestones include: (i) recognition in 1980 of cryptosporidiosis as an acute enteric disease; (ii) its

81 Cryptosporidiosis as an initial AIDS-defining diagnosis

82 PK1) are leading candidates for treatment of cryptosporidiosis-associated diarrhea.

83 Differences in the incidence of cryptosporidiosis between bottled and municipal water gr

84 the first report of possible transmission of cryptosporidiosis between humans and dogs.

85 with effective therapy in the mouse model of cryptosporidiosis, but a more refined model for efficacy

86 or immunotherapies have been identified for cryptosporidiosis, but certain antibodies directed again

87 arded weight gain more than did asymptomatic cryptosporidiosis, but the latter was twice as common.

88 testinal fluid secretion in animal models of cryptosporidiosis, but their cellular sources and mechan

89 ren completing follow-up, 397 (97%) acquired cryptosporidiosis by 3 years of age.

90 plays an important role in the resolution of cryptosporidiosis by attracting immune effector cells to

91 tein malnutrition may enhance (or intensify) cryptosporidiosis by suppressing C. parvum-induced cell

92 ldren with a symptomatic diarrhea episode of cryptosporidiosis (case-children) were compared with tho

93 ch Transplantation Society, we collected all cryptosporidiosis cases identified in solid organ transp

94 utbreaks account for only 10% of the overall cryptosporidiosis cases, and there are few data on the s

95 Cryptosporidiosis, caused by Cryptosporidium parvum, is

96 Cryptosporidiosis, caused by the apicomplexan parasite C

97 Cryptosporidiosis, caused by the apicomplexan parasite C

98 Cryptosporidiosis, caused by the protozoan parasite Cryp

99 nts had additional immunodepression favoring cryptosporidiosis (CD40 ligand deficiency [n = 1], human

100 diseases, including malaria, toxoplasmosis, cryptosporidiosis, coccidiosis and babesiosis.

101 ignificantly increased in AIDS patients with cryptosporidiosis compared to the level in AIDS patients

102 Cryptosporidiosis continues to challenge old and new che

103 pothesized that passive immunization against cryptosporidiosis could be improved by using neutralizin

104 e human immunodeficiency virus (HIV) in whom cryptosporidiosis developed during the outbreak.

105 ns: 1) How do AIDS patients who present with cryptosporidiosis differ from other patients with AIDS?

106 Cryptosporidiosis drug and vaccine development is limite

107 We established an in vitro model of biliary cryptosporidiosis employing a human biliary epithelial c

108 as epidemiologic tools for the detection of cryptosporidiosis episodes in children from a Peruvian c

109 No reliable therapy for cryptosporidiosis exists, though the aminoglycoside paro

110 intraepithelial lymphocytes from calves with cryptosporidiosis expressed IFN-gamma but not TNF-alpha.

111 Malnutrition and cryptosporidiosis form a vicious cycle and lead to acute

112 In biopsies from AIDS patients with active cryptosporidiosis, four chemokines (CXCL10, CCL11 [eotax

113 On average, children with symptomatic cryptosporidiosis gained (i.e., grew) 342 g less (95% co

114 Cryptosporidiosis, giardiasis and microsporidiosis are s

115 The role of dogs and cats in human cryptosporidiosis has been the focus of much attention.

116 However, its role in cryptosporidiosis has not been fully studied.

117 effective in treating people suffering from cryptosporidiosis has prompted the development of in viv

118 Although several animal models of cryptosporidiosis have been reported, most involve genet

119 the developing world, current therapies for cryptosporidiosis have limited efficacy.

120 t models for evaluating drug therapy against cryptosporidiosis have many limitations, including the n

121 well-established as a source in outbreaks of cryptosporidiosis; however, the role of tap water in end

122 e patients received specific therapy against cryptosporidiosis ie nitozoxanide, 25 in monotherapy, an

123 3) Does a diagnosis of cryptosporidiosis impact survival after AIDS diagnosis?

124 d microbiology records identified 3 cases of cryptosporidiosis in 1992 (the first year that cryptospo

125 dentified microsporidiosis in 7 patients and cryptosporidiosis in 2 patients.

126 infection-related complications, with severe cryptosporidiosis in 6.

127 istently effective antiparasitic therapy for cryptosporidiosis in AIDS.

128 Cryptosporidiosis in Bangladeshi children aged 2-5 year

129 has been linked by several investigators to cryptosporidiosis in humans.

130 ere highly protective against development of cryptosporidiosis in immune-suppressed HIV-infected pers

131 ay be important in controlling the burden of cryptosporidiosis in immunosuppressed individuals.

132 Thus, the transmission of cryptosporidiosis in Kuwaiti children differed significa

133 The increased risk of cryptosporidiosis in MBL deficiency appears to include p

134 ts of MBL deficiency appear to predispose to cryptosporidiosis in patients with the acquired immunode

135 There is a high burden of endemic cryptosporidiosis in southern India.

136 ess, but few studies have evaluated sporadic cryptosporidiosis in the United States.

137 es is often reported as the primary cause of cryptosporidiosis in this country.

138 s study we found that most sporadic cases of cryptosporidiosis in Wisconsin are caused by zoonotic Cr

139 s of Cryptosporidium in 49 cases of sporadic cryptosporidiosis in Wisconsin during the period from 20

140 In Scotland, rates of cryptosporidiosis infection in humans peak during the sp

141 ring 2002, there was recovery in the rate of cryptosporidiosis infection in humans throughout Scotlan

142 as a significant reduction in human cases of cryptosporidiosis infection in southern Scotland, where

143 We associate the reduction in human cases of cryptosporidiosis infection with the reduction in the nu

144 Nitazoxanide (NTZ), originally used to treat cryptosporidiosis infection, recently was shown to have

145 Cryptosporidiosis is a common cause of diarrhea morbidit

146 Cryptosporidiosis is a late posttransplant infection tha

147 Cryptosporidiosis is a serious disease in malnourished c

148 Cryptosporidiosis is a significant cause of food-borne a

149 Although the clinical severity of cryptosporidiosis is altered by human immunodeficiency v

150 Cryptosporidiosis is an emerging infectious disease that

151 Cryptosporidiosis is an important diarrheal disease of h

152 Biliary cryptosporidiosis is associated with acquired immunodefi

153 Cryptosporidiosis is classically reported in patients wi

154 Cryptosporidiosis is increasingly identified as an impor

155 Since asymptomatic cryptosporidiosis is more prevalent, it may have more of

156 However, the current treatment for cryptosporidiosis is suboptimal.

157 The GKO mouse model of cryptosporidiosis is useful for discerning isolate-speci

158 These infections include cryptosporidiosis, isosporiasis, and microsporidiosis.

159 lows: toxoplasmosis, 91% and 86 (5.24/0.06); cryptosporidiosis/isosporiasis, 90% and infinite (1.61/0

160 June 1994; at least 20 of the 32 (62.5%) had cryptosporidiosis listed on their death certificates.

161 uggests that acquired protective immunity to cryptosporidiosis may be important in controlling the bu

162 A total of 186 episodes of cryptosporidiosis, mostly asymptomatic, were observed in

163 rgan transplant recipients (41 kidneys) with cryptosporidiosis, mostly men (68%), with a median age o

164 trates that malnourished children with acute cryptosporidiosis mount inflammatory, Th-2, and counterr

165 lunteers who developed signs and symptoms of cryptosporidiosis (n = 11) than among asymptomatic infec

166 Cryptosporidiosis occurred at a median time of 3.4 (0-19

167 In 1994, an outbreak of cryptosporidiosis occurred in a rural community in Washi

168 cryptosporidium and a widespread outbreak of cryptosporidiosis occurred.

169 ons who drank only bottled water to have had cryptosporidiosis (odds ratio, 4.22 [95% Cl, 1.22 to 14.

170 ral gene mutations were at increased risk of cryptosporidiosis (odds ratio, 8.2; 95% confidence inter

171 gest that treatment with IFN-gamma may limit cryptosporidiosis of the small intestine.

172 Fifty-eight (25.7%) had cryptosporidiosis, of whom 17 (29.3%) had recurrent dise

173 nanoparticles for the molecular diagnosis of cryptosporidiosis, offering new opportunities for the fu

174 nfection, as well as the community impact of cryptosporidiosis on this population.

175 sporidiosis and healthy volunteers with mild cryptosporidiosis or asymptomatic infection after experi

176 mpared to the level in AIDS patients without cryptosporidiosis or in normal volunteers (median in AID

177 In September and October 1998, a cryptosporidiosis outbreak occurred on a Washington, DC,

178 A cryptosporidiosis outbreak was associated with municipal

179 Most cryptosporidiosis outbreaks in the United States have be

180 nd 31 March 2014, concurrent shigellosis and cryptosporidiosis outbreaks occurred among men who have

181 ocyte count (P<.0001), no ART (P<.0001), and cryptosporidiosis (P=.004) but not with microsporidiosis

182 r ongoing public health education to prevent cryptosporidiosis, particularly among travelers, animal

183 ly recognized by serum antibodies from human cryptosporidiosis patients.

184 pecimens from asymptomatic subjects and from cryptosporidiosis patients.

185 Children with cryptosporidiosis presented early, and most had abdomina

186 months was associated with a higher risk of cryptosporidiosis (rate ratio [RR] = 1.40; 95% confidenc

187 fic drugs, vaccines, and immunotherapies for cryptosporidiosis relates in part to limited knowledge o

188 rvival of AIDS patients with newly diagnosed cryptosporidiosis relative to patients with other AIDS-d

189 Thus, the pathogenesis of cryptosporidiosis remains poorly characterized, and inte

190 wimming pool outbreaks of cyclosporiasis and cryptosporidiosis, respectively, occurred in North Ameri

191 Symptomatic cryptosporidiosis retarded weight gain more than did asy

192 sociation between drinking bottled water and cryptosporidiosis suggests possible spread from asymptom

193 tion in neonatal calves, a clinical model of cryptosporidiosis that closely resembles human infection

194 ing the interaction between malnutrition and cryptosporidiosis through immunostaining and immunoblott

195 This outbreak illustrates the potential for cryptosporidiosis to cause foodborne illness.

196 human and animal diseases, such as malaria, cryptosporidiosis, toxoplasmosis, and coccidiosis, and n

197 In vitro models of biliary cryptosporidiosis using a human biliary epithelial cell

198 ere noted in patients with AIDS with chronic cryptosporidiosis versus immunocompetent volunteers with

199 s reportedly taking clarithromycin developed cryptosporidiosis vs 30 of the 707 patients not taking c

200 the 214 patients taking rifabutin developed cryptosporidiosis vs 33 of the 805 not taking rifabutin

201 Cryptosporidiosis was complicated by renal failure in 15

202 s/mm3, the association between tap water and cryptosporidiosis was even stronger (odds ratio, 13.52 [

203 The effect of asymptomatic cryptosporidiosis was less severe: On average, children

204 idium a century ago, and for almost 70 years cryptosporidiosis was regarded as an infrequent and insi

205 yptosporidiosis in 1992 (the first year that cryptosporidiosis was reportable in Nevada), 23 cases in

206 Using an in vitro model of human biliary cryptosporidiosis, we found that recombinant Tat protein

207 Using an in vitro model of human intestinal cryptosporidiosis, we report here that some of these C.

208 ith both control groups, children with acute cryptosporidiosis were more malnourished (including meas

209 gressive multifocal leukoencephalopathy, and cryptosporidiosis were the least common disorders, with

210 Treatment of cryptosporidiosis with azithromycin and paromomycin was

211 nhibitors could potentially be used to treat cryptosporidiosis with minimal effects on its mammalian

212 PCR identified 1053 episodes of cryptosporidiosis, with an overall incidence of 0.86 inf