ライフサイエンスコーパス: crystallographically

1 some of the higher-order assemblies observed crystallographically.

2 examined kinetically, spectroscopically, and crystallographically.

3 ational fluctuations that have been observed crystallographically.

4 nions in [Cs(C21 H11(-) )2 ](-) was revealed crystallographically.

5 chieve final poses matching those determined crystallographically.

6 y the "inactive-like" configuration observed crystallographically.

7 n treatment with CO(2) and was characterized crystallographically.

8 P2 in complex with Rab11 that was determined crystallographically.

9 be followed optically, spectroscopically and crystallographically.

10 ey are disordered and therefore undetectable crystallographically.

11 BF4 were characterized spectroscopically and crystallographically.

12 nyl analogue of which has been characterized crystallographically.

13 ogically and on protein structure determined crystallographically.

14 2*bipy, and 2*tmeda have been characterized crystallographically.

15 o the 3-phosphoglycerate molecule identified crystallographically.

16 2C2H4)(mu-CO)(CN)2(PPh3)2(CO)2, as confirmed crystallographically.

17 e structure has not previously been observed crystallographically.

18 (5))I (6), which has also been characterized crystallographically.

19 st, but not all, of which have been detected crystallographically.

20 rms deviation from the structures determined crystallographically.

21 ary reactants and subsequently characterized crystallographically.

22 haracterized this virus-receptor interaction crystallographically.

23 ate NMR and biochemical techniques but never crystallographically.

24 h symmetry of the His6 binding site observed crystallographically.

25 nt with the pentamer-of-dimers assembly seen crystallographically.

26 steric changes in AMA1 that are not observed crystallographically.

27 e., H(2)O.4H(2)O or F(-).4H(2)O, as observed crystallographically.

28 precursors, and elucidated germline binding crystallographically.

29 e unpaired base of the DNA template observed crystallographically (-11C) could also be removed withou

30 Br(2) allowed us to isolate and characterize crystallographically a very unusual mononuclear, paramag

31 The nanocrystals became crystallographically aligned early in the overall self-a

32 of dislocations through the interiors of the crystallographically aligned grains.

33 is minimized by the use of relatively large, crystallographically aligned grains.

34 tals are composed of spatially separated and crystallographically aligned nanocrystals.

35 We characterize crystallographically an early intermediate along the rea

36 of two stereoisomers, the one characterized crystallographically and a contribution of about 10% fro

37 e, the SSB-binding site on chi is identified crystallographically and biochemical and cellular studie

38 ne (Y215F, Y215H) were analyzed kinetically, crystallographically and by molecular dynamics simulatio

39 One of these is characterized crystallographically and contains a C4 ligand oxygen bou

40 is also square-planar, and was characterized crystallographically and has tau4=0.13.

41 Here we show crystallographically and in solution that the ATP-depend

42 his process can be traced in the solid state crystallographically and in solution using dynamic light

43 O)(CNMe)(6)](PF(6))(2) (n = 2,3) established crystallographically and spectroscopically, are quite si

44 ed of highly crystalline hydroxyapatite that crystallographically and structurally differs from bone

45 erichia coli, has been structurally resolved crystallographically and subjected to intensive mutagene

46 These results corroborate those obtained crystallographically and, importantly, provide structura

47 a5-C5H5)Br2(R,R-phospholane)] (characterized crystallographically) and [Rh(eta5-C5H5)(H)2(R,R-phospho

48 These compounds were characterized crystallographically, and also by NMR, EPR, electrochemi

49 was confirmed spectroscopically, chemically, crystallographically, and analytically.

50 sequence (C/CGG) and binds to that sequence crystallographically as a monomer.

51 iolato hydride, [3H]BF(4), was characterized crystallographically: as anticipated by biophysical stud

52 ominally disordered inverse structure orders crystallographically at low T, and (ii) at finite temper

53 We present results of the restoration of all crystallographically available intra- and extracellular

54 However, few of them have been characterized crystallographically, because they are either too reacti

55 Although neither THF nor Ph(3)PO formed crystallographically characterizable (C(5)Me(5))(3)LaL(x

56 The first crystallographically characterizable complex of Sc(2+) ,

57 The first examples of crystallographically characterizable complexes of Tb(2+)

58 ghly reactive due to steric crowding and few crystallographically characterizable Th(3+) complexes ar

59 trate analogue, we were now able to trap and crystallographically characterize various stages in the

60 Addition of Me(3)CCN to 1 produced the first crystallographically characterized (C(5)Me(5))(3)ML(2) c

61 (mu-H) and the proton of the (mu-NH) of the crystallographically characterized 3 show the proposed s

62 This crystallographically characterized 6-isocyano-2-formamid

63 In particular, we have crystallographically characterized a diamagnetic arylnic

64 via the primary amine moiety, affording the crystallographically characterized adduct [(L1)Pd(p-toly

65 ver complexes 3a and 3b are rare examples of crystallographically characterized Ag(I) cyclopentadieny

66 We have also crystallographically characterized an aralkylpalladium(I

67 A crystallographically characterized analog (Et4N)2[Co(L)C

68 obalt catalyst, 6-(H)2BPin, was prepared and crystallographically characterized and proved inactive f

69 The two compounds were crystallographically characterized and studied by absorp

70 dral Zintl ion [Fe@Ge(10)](3-) (1) which was crystallographically characterized as a [K(2,2,2-crypt)]

71 y led to a six-membered heterocycle that was crystallographically characterized as containing the -N(

72 he unusual catalytic CODH C-cluster has been crystallographically characterized as either a NiFe(4)S(

73 ded contact distance is the shortest for any crystallographically characterized compound.

74 nt study probes this issue by examining four crystallographically characterized Cu/aminoxyl halide co

75 nds are significantly shorter than any other crystallographically characterized d-f-block bimetallic,

76 vity of 2 with that of a more electron-rich, crystallographically characterized derivative, [Fe(III)S

77 Compounds 1-3 represent a rare series of crystallographically characterized diphosphenes bearing

78 or-arrested inclusion complexes, including a crystallographically characterized encapsulated Au(III)

79 We report the first crystallographically characterized examples of molecular

80 hen the metal is La, Ce, Pr, or U, the first crystallographically characterized examples of the tetra

81 y scattering (SAXS) and compared to existing crystallographically characterized Fe protein conformati

82 osed S-bound dimethyl sulfoxide ligands in a crystallographically characterized form), then olefin in

83 the [Au18(SC6H11)14] cluster is the smallest crystallographically characterized gold cluster protecte

84 ond" cores, including the first example of a crystallographically characterized heterobimetallic bis(

85 Compound 2 is the first example of a crystallographically characterized hydride complex in wh

86 (CH(2)CH(CH(2))(2))](2-), respectively, were crystallographically characterized in compounds with [K-

87 These results represent the first crystallographically characterized magnesium and zinc ca

88 A series of seven crystallographically characterized Mn monomers and dimer

89 (2)NBn](CO)(4)(dppn)](+) ([2](+)), the first crystallographically characterized model for the H(ox) s

90 This is a rare example of an isolable and crystallographically characterized phenoxyl radical and

91 m addition of a suitable amine-borane to the crystallographically characterized precursor [Rh(eta(6)-

92 n structures previously observed for over 40 crystallographically characterized rare-earth metal (N h

93 Isolation of the first crystallographically characterized REMB complex with sub

94 rylamine) "bipolarons": we have isolated and crystallographically characterized salts of the dication

95 We report herein a crystallographically characterized synthetic Cu(II)2(mu-

96 (DO2A)(DPA)(-) complex solutions (1.0 microM crystallographically characterized TBA x Eu(DO2A)(DPA))

97 (BF(4))(2) represents the first example of a crystallographically characterized terminal hydride prod

98 A crystallographically characterized three-coordinate, for

99 are reported for central glycyl residues in crystallographically characterized tripeptides with alph

100 ilized methylidenes candium complex has been crystallographically characterized, and its bonding sche

101 enium oxyanion complexes have been prepared, crystallographically characterized, and screened for the

102 Both Ge(TPP) and Ge(TPP)(py)2 have been crystallographically characterized, and the antiaromatic

103 Both products were crystallographically characterized, and the latter react

104 The series of zinc alkylperoxides is crystallographically characterized, and the structures s

105 conocene sandwich yields a rare example of a crystallographically characterized, base-free eta5,eta5-

106 The AgOTf complex, which was crystallographically characterized, exhibits a structure

107 exes nor their fleeting precursors have been crystallographically characterized, hindering direct exp

108 s of the quinoline-annulated porphyrins were crystallographically characterized, proving their connec

109 hthylpurine derivative has been obtained and crystallographically characterized.

110 N]Mo(NB(C6F5)3) complexes (n = 1 and 3) were crystallographically characterized.

111 ity, several large PAHs were synthesized and crystallographically characterized.

112 duct [Fe(II)(N3PySO(2))(NCS)] (2), which was crystallographically characterized.

113 ranium vinyl complexes that are reported and crystallographically characterized.

114 ate and resulting Pd-alkyl species have been crystallographically characterized.

115 All of these systems were crystallographically characterized.

116 NH(2)-BH(3))Cl(2)(thf)(3), 3, which has been crystallographically characterized.

117 were sufficiently stable to be isolated and crystallographically characterized.

118 zincate has also been spectroscopically and crystallographically characterized.

119 2))(P(i)Bu(3))(2)][BAr(F)(4)] have also been crystallographically characterized.

120 talloindene complexes have been isolated and crystallographically characterized.

121 .NHMe(2))][BAr(F)(4)], has been isolated and crystallographically characterized.

122 gen compounds were isolated and in one case, crystallographically characterized.

123 ) that have been isolated in good yields and crystallographically characterized.

124 which was isolated as the triflate salt and crystallographically characterized.

125 the monomeric (IPr**)AgH complex, which was crystallographically characterized.

126 xo-syn-isomer 8, which has been isolated and crystallographically characterized.

127 o)ethylene) complex has been synthesized and crystallographically characterized.

128 OEt(2) 5, PPh(3) 6,) both of which have been crystallographically characterized.

129 salts, which have been spectroscopically and crystallographically characterized.

130 )] and Cs3[U(III---)-N-(---U(III)] have been crystallographically characterized.

131 etic complex 3 [Ni(Ph)(PN(P)N(H))], which is crystallographically characterized.

132 d Cu(II) complexes have been synthesized and crystallographically characterized.

133 es were also synthesized, and the latter was crystallographically characterized.

134 lPhos, L2) was prepared in 63% yield and was crystallographically characterized; the [Pd(cinnamyl)Cl]

135 periodically layered zig-zag architecture of crystallographically co-oriented calcite lamellae.

136 del system that has been fully characterized crystallographically, computationally and kinetically.

137 space in the presence and absence of several crystallographically conserved and buried water molecule

138 mpetent to bind the inhibitor BIRB796 in the crystallographically correct position and with docked en

139 large external cleft, the cleft itself, the crystallographically defined binding pocket, and the gat

140 ecular dynamics study in which we analyzed a crystallographically defined complex that involves the H

141 d to define the electronic structures of two crystallographically defined Cu(II)-phenolate complexes.

142 cytochrome c peroxidase (rCcP), in which the crystallographically defined cytochrome c binding site i

143 forms oligomers more readily, suggesting the crystallographically defined dimer interface is one of t

144 le receptors active in cells verify that the crystallographically defined HAMP conformers are maintai

145 The crystallographically defined interface is shown to be co

146 protein designed to disrupt contacts in the crystallographically defined interface.

147 omote arrestin-2 oligomerization via the two crystallographically defined ligand-binding locations.

148 to directly calculate the EXAFS spectrum of crystallographically defined model complexes.

149 00000 compounds for predicted binding to the crystallographically defined nucleotide binding region o

150 relaxation measurements, we demonstrate that crystallographically defined superatomic solids assemble

151 imilar position in the bovine structure, the crystallographically defined, conserved steroid binding

152 is greatly enhanced by residues flanking the crystallographically-defined recognition motif, apparent

153 an that of DeltaGly-141, consistent with its crystallographically demonstrated more rigid loop.

154 ial diastereomers, lending strong support to crystallographically derived models of aminoglycoside-ri

155 Data Bank entries 1EHK and 1XME ), having a crystallographically detectable water between the Cu(B)

156 traces of the homology-modeled CTP onto the crystallographically determined ADP carrier structure in

157 ey amino acids at the active site, as in the crystallographically determined APE1 complexed with an A

158 We also show that crystallographically determined binding site locations r

159 forming a complex virtually identical to the crystallographically determined bound structure.

160 quality of these maps allowed us to build in crystallographically determined conformations of kinesin

161 esence of side-chain residues fixed at their crystallographically determined coordinates.

162 (30) (x approximately 60), 2, as the largest crystallographically determined discrete transition meta

163 a coarse-grained dynamics method comes to a crystallographically determined intermediate structure w

164 h a set of five proteins with at least three crystallographically determined on-pathway high-resoluti

165 to generate ligand conformations similar to crystallographically determined protein/ligand complex s

166 The release of one sodium ion from the crystallographically determined sodium binding site Na2

167 the direction, amplitude, and time scales of crystallographically determined structural changes.

168 abilized Et(3)BNH(2)BH(3)(-) anion, with the crystallographically determined structure of the [Et(3)B

169 While the crystallographically determined structure of the enzyme

170 hiolate-protected Au nanoparticle that has a crystallographically determined structure.

171 By fitting the crystallographically determined structures of these Fab

172 for {ES-NO}7 are in good agreement with the crystallographically determined substrate-bound active s

173 In this study, we have crystallographically determined the 3D structure of the

174 Crystallographically determined, apparent dissociation c

175 e shape comparisons are made relative to the crystallographically determined, bioactive conformation

176 e distinct electronic spin states reveal two crystallographically different iron(II) sites, and analy

177 teracting with one or more Ge atoms in three crystallographically different molecules in the structur

178 lr(Mtb) is found to be a dimer formed by two crystallographically different monomers, each comprising

179 tes that have identical hole density but are crystallographically different outside of the CuO(2) pla

180 -pair salt isolated as K(L(C))(+)//DNB(-) is crystallographically differentiated from the "contact" i

181 g the conformations of a mobile loop that is crystallographically disordered in both prior crystal st

182 ion of the primary sequence corresponds to a crystallographically disordered loop adjacent to the act

183 These materials are crystallographically disordered on the atomic scale, but

184 ique information regarding the function of a crystallographically disordered segment of the loop near

185 ut that 214 residues, including the NTD, are crystallographically disordered.

186 compounds of the type [CuLCl](2), identified crystallographically, dissociate in solution to give mon

187 aces is linked to simultaneous growth of the crystallographically distinct (001) basal plane.

188 forms islands that are compact in shape with crystallographically distinct boundaries that have essen

189 phase to be Mn(19)Si(33), one of a series of crystallographically distinct higher manganese silicides

190 The complex studied has two crystallographically distinct iron sites; one site has a

191 hese two polymorphs of NaNbO(3) contains two crystallographically distinct Na sites.

192 g salts of [1]+, which were characterized by crystallographically, EPR, and elemental analyses.

193 absence of dynamics but the boron pairs are crystallographically equivalent or (2) the boron pairs a

194 tides form parallel-stranded duplexes with a crystallographically equivalent strand, resulting in the

195 tensive single amino acid mutagenesis within crystallographically established domains, manipulation o

196 The total number of crystallographically estimated Pt atoms, 8 +/- 3, which

197 formations of EGFR kinase have been resolved crystallographically, experimental characterization of t

198 Pm3n cubic, 3-D P4(2)/mnm tetragonal, and a crystallographically forbidden 12-fold symmetry liquid q

199 ahedral and icosahedral symmetry, exhibiting crystallographically forbidden five-fold symmetry elemen

200 This Ndelta hydrogen, which crystallographically has no hydrogen-bonding partner and

201 ty due to the Sn(2+) s(2) lone pair causes a crystallographically hidden, locally distorted state to

202 environments, and the divalent metal site is crystallographically identified and has a Phpy ligand at

203 of phosphatidyl-4,5-bisphosphate (PIP2) at a crystallographically identified binding site, but an add

204 On the basis of crystallographically identified cation-binding sites at

205 are consistent with one another and with the crystallographically identified contact residues.

206 ments between LeuT and vSGLT reveal that the crystallographically identified galactose-binding site i

207 Mutations of the crystallographically identified metal-binding residues h

208 recluded correlation of EPR signals with the crystallographically identified monocopper and dicopper

209 The molecule has crystallographically imposed C(2) symmetry.

210 modimer, previous structures have captured a crystallographically-imposed symmetric state.

211 ocktails, four compounds could be identified crystallographically in the active site.

212 ay, and its structure has been characterized crystallographically in the apo-state, in the metal-boun

213 The structure approximates that established crystallographically in the C-cluster of C. hydrogenofor

214 Five crystallographically independent 1D channels including t

215 There are two crystallographically independent Fab fragments in the as

216 A comparison of two crystallographically independent flexizyme conformations

217 The two crystallographically independent ligand molecules adopt

218 embly-competent CA hexamers and derived four crystallographically independent models that define the

219 nd-to-end twist of 144 degrees , and the two crystallographically independent molecules of 2m have tw

220 c showed that the structures consist of four crystallographically independent molecules, A, B, C, and

221 coordination sphere of the metals in the two crystallographically independent orientations is identic

222 ad-to-tail overlap complexes in four of five crystallographically independent parallel dimers.

223 ray diffraction indicated that one out of 15 crystallographically independent phosphorus atoms appear

224 ns are found in each active site of the four crystallographically independent subunit copies in the H

225 Two crystallographically independent views reveal that the c

226 d along the chain due to the presence of two crystallographically independent {Mn2(saltmen)2} units,

227 nium ion or N-acetylgalactal form, which are crystallographically indistinguishable at the present re

228 ically equivalent or (2) the boron pairs are crystallographically inequivalent but are rendered magne

229 tra yield isotropic chemical shifts for each crystallographically inequivalent carbon and spin-lattic

230 Each crystalline form contains two crystallographically inequivalent clusters with the same

231 ure superconductors (HTSCs) that possess two crystallographically inequivalent CuO(2) planes in the u

232 the successful, prospective optimization of crystallographically intractable fragment hits into more

233 re of the rat endophilin A1 dimer determined crystallographically is maintained under predominantly v

234 25(SCH 2CH 2Ph) 18 nanoparticle structure is crystallographically known to consist of a centered Au 1

235 Channels filled with crystallographically located water and acidic groups are

236 the soluble region of pmoB at the site of a crystallographically modeled dicopper center.

237 NA glycosylase AlkD from Bacillus cereus, we crystallographically monitored excision of an alkylpurin

238 osphine (SP)-PMeIs(p-MeOC6H4) was determined crystallographically; NMR studies and comparison to the

239 nodes and seven tricarboxylate ligands (both crystallographically nonequivalent), resulting in a 173.

240 two end facets of wurtzite CdS nanorods are crystallographically nonequivalent, asymmetric heterostr

241 This observation suggests that some of the crystallographically observed allosteric effects that re

242 ere interpreted as being consistent with the crystallographically observed ARD structure.

243 The crystallographically observed binding interface was conf

244 Finally, we demonstrate that the crystallographically observed conformation of the mobile

245 pontaneously from the active to the inactive crystallographically observed conformation.

246 h the isotropic thermal fluctuations and the crystallographically observed conformational changes wit

247 lated conformation of 2 agreed well with the crystallographically observed conformations of 1 and 2.

248 ree nucleotide states could sample the major crystallographically observed conformations.

249 We also confirm that a crystallographically observed disorder to order transiti

250 observed crystal structure but maintain key crystallographically observed hydrogen bonds still have

251 as of Get3 open and closed structures in the crystallographically observed no-nucleotide, two ATP, an

252 orientation is very close (<1 A RMSD) to the crystallographically observed orientation in most cases,

253 rather than C-8, indicating that the second crystallographically observed orientation is significant

254 Crystallographically observed structural changes (e.g.,

255 e actinyl tetrahalide dianions and reconcile crystallographically observed structural motifs and non-

256 or requires an extension of the lever arms' crystallographically observed structure.

257 rameworks are covalently functionalized with crystallographically ordered pendant metal clusters have

258 The only previous crystallographically proven 26- and 29-atom DI members a

259 pret such data in terms of a small number of crystallographically refinable, time-independent structu

260 The crystallographically refined occupancies of these confor

261 Both phases are crystallographically related to the parent beta (BCC) ma

262 ng kinetic model at two levels: first, using crystallographically relevant internal cavities and thei

263 eta(2)-side S,O-bound (MS2) photoisomers are crystallographically resolved by probing a light-induced

264 rmational transition pathways connecting the crystallographically resolved conformations.

265 om a molecular dynamics (MD) simulation of a crystallographically resolved IN/inhibitor complex revea

266 We find that crystallographically resolved Ti17O24(OPr(i))20 nanopart

267 ructure of these Lewis pairs was established crystallographically, revealing an additional Ru-Al inte

268 ay scattering studies confirm the state seen crystallographically, showing that the DnaB ATPase domai

269 slippage in boron nitride nanotubes that are crystallographically similar to carbon nanotubes, but el

270 [K(2.2.2-cryptand)][Cp'3UH], which could be crystallographically similar, the hydride complex was sy

271 A crystallographically symmetric dimer binds no ligands.

272 e, or l-cysteine-l-phosphotyrosine formed on crystallographically textured films of gold, we conclude

273 r high temperature properties without HRE, a crystallographically textured nanoscale grain structure

274 We determine crystallographically that NurA folds in a toroidal dimer

275 on of the human EGFR dimer has been resolved crystallographically, the crystal structures do not reve

276 ncluding the transmembrane pocket identified crystallographically, the extracellular (EC) domain, and

277 fusion hairpin forms have been characterized crystallographically, the transiently extended prehairpi

278 nel is the "mobile" Glu(292), which was seen crystallographically to adopt distinct positions up and

279 oxygenating 1 in CH(2)Cl(2) were identified crystallographically to be [Fe(2)(mu-OH)(2)(mu-O(2)CAr(T

280 the most soluble, with a paratope we showed crystallographically to be virtually identical to that o

281 were calculated for the three systems known crystallographically to contain cations in close contact

282 isons among all the multi-domain NRs studied crystallographically to date show significant variations

283 the longest 3(10) helical structure observed crystallographically to date.

284 r(f)(4)](-) (9) can be synthesized and shown crystallographically to feature a terminally bound GaI l

285 um Neisseria meningitidis (NmHO) possesses a crystallographically undetected C-terminal fragment that

286 l 2-fold and mirror symmetry, exhibits three crystallographically unique one-dimensional channels as

287 The two structures contain five crystallographically unique subunits of MntR, providing

288 The overlay of eight crystallographically unique U3S molecules reveals a huge

289 vel, because such boundary is, in principle, crystallographically unobservable.

290 Examples for n = 1 and 3 have been crystallographically verified for R = 2,6-iPr2C6H3 (Dipp

291 carbamic acid pairs, the latter of which are crystallographically verified for the first time in a po

292 y establish a FeCO vibrational signature for crystallographically verified pentacoordination.

293 n one case, the B-H bond activation step was crystallographically verified, a snapshot of the sigma-b

294 y example in which the parent phenol is also crystallographically well-defined.

295 e structures of Fab fragments not determined crystallographically were predicted by homology modeling

296 o "open/closed" states previously identified crystallographically, were indicated to have direct effe

297 GlcN6P binding becomes apparent crystallographically when the pH is raised to 8.5, where

298 ly resembles the CFeSP/MeTr complex observed crystallographically with 2:1 protein stoichiometry, whi

299 plex is the first such complex to be trapped crystallographically with a DD-peptidase.

300 This could in theory be achieved crystallographically with a structure whose three-dimens