ライフサイエンスコーパス: cubitus

1 : fused (a protein-serine/threonine kinase), cubitus interruptus (a transcription factor), and costal

2 form of the zinc-finger transcription factor Cubitus interruptus (Ci(155)), the main effector of Hh s

3 sion by the zinc-finger transcription factor Cubitus interruptus (Ci(rep)).

4 he kinase Fused and the transcription factor Cubitus interruptus (CI) act positively upon targets.

5 hile the F box protein Slimb is required for Cubitus interruptus (Ci) and Armadillo/beta-catenin (Arm

6 e formation of a truncated repressor form of Cubitus interruptus (Ci) and by stimulating the nuclear

7 ugh phosphorylating the transcription factor Cubitus interruptus (Ci) and G protein coupled receptor

8 The Cubitus interruptus (Ci) and Gli proteins are transcript

9 f Hh are the zinc-finger containing proteins Cubitus interruptus (Ci) and Gli, in flies and vertebrat

10 -regulated transcription factors, Drosophila Cubitus interruptus (Ci) and mammalian Gli proteins.

11 e formation of a truncated repressor form of Cubitus interruptus (Ci) and stimulating the transcripti

12 ctivation of vn is mediated through the gene cubitus interruptus (ci) and that this activation requir

13 hh in the germarium, while patched (ptc) and cubitus interruptus (ci) are expressed in somatic cells

14 Recent progress has unveiled Cubitus interruptus (Ci) as a complex transcription fact

15 tes the function of the transcription factor Cubitus interruptus (Ci) at three levels: protein stabil

16 oreover, we find that activated Fu regulates Cubitus interruptus (Ci) by both promoting its transcrip

17 ers the activity of the transcription factor Cubitus interruptus (Ci) by inhibiting the proteolysis o

18 cubitus interruptus (ci) encodes a transcription factor

19 The Drosophila segment polarity gene cubitus interruptus (ci) encodes a zinc finger protein t

20 The Gli/Cubitus interruptus (Ci) family of transcription factors

21 The Drosophila cubitus interruptus (ci) gene encodes a sequence-specifi

22 lated processing of the transcription factor cubitus interruptus (Ci) in Drosophila depends on phosph

23 ate the activity of the transcription factor Cubitus interruptus (Ci) in response to the Hh signal.

24 Cubitus interruptus (Ci) is a transcriptional factor tha

25 The segment polarity gene cubitus interruptus (ci) maps to the most intensively st

26 phorylation by PKA, GSK3, and CKI to prevent Cubitus interruptus (Ci) processing through unknown mech

27 a direct transcriptional requirement for the Cubitus interruptus (Ci) protein.

28 e known Hh cytoplasmic components, including Cubitus interruptus (Ci) the only known target of Hh sig

29 n Hh signaling by regulating the activity of Cubitus interruptus (Ci) through phosphorylation of the

30 The Hedgehog (Hh) signal is transduced via Cubitus interruptus (Ci) to specify cell fates in the Dr

31 expression, accomplished through binding of Cubitus interruptus (Ci) to the Cyclin E promoter, media

32 Cubitus interruptus (Ci), a Drosophila transcription fac

33 Overexpressing the repressor form of Cubitus interruptus (Ci), a Hh pathway antagonist, also

34 , a protein secreted by posterior cells, and Cubitus interruptus (Ci), a protein in the Hh response p

35 In Drosophila, Hh transduces its signal via Cubitus interruptus (Ci), a transcription factor present

36 the secreted protein, Hedgehog (Hh), and by Cubitus interruptus (Ci), a transcriptional effector of

37 ns of Hh have been shown to be transduced by Cubitus interruptus (Ci), a zinc finger transcription fa

38 l for activation by the transcription factor Cubitus interruptus (Ci), and a cluster of binding sites

39 tial proteolysis of the transcription factor Cubitus interruptus (Ci), and the ability of a complex c

40 his complex, Costal2 (Cos2), Fused (Fu), and Cubitus interruptus (Ci), bind each other directly to fo

41 e Fused (Fu), and the Drosophila Gli homolog cubitus interruptus (Ci), in two distinct manners.

42 In Drosophila the Gli homolog, cubitus interruptus (CI), is expressed only in the anter

43 BP, interacts with the transcription factors Cubitus interruptus (CI), MAD, and Dorsal (DL) and funct

44 els and rate of nuclear entry of full-length Cubitus interruptus (Ci), the Hh signaling target, are e

45 We mapped chromatin binding sites for Cubitus interruptus (Ci), the transcription factor that

46 ence of Hh, the sole Drosophila Gli homolog, Cubitus interruptus (Ci), undergoes partial proteolysis

47 creased stability of a transcription factor, Cubitus interruptus (Ci), whereas Wg signal transduction

48 a vertebrate homolog of the Drosophila gene cubitus interruptus (ci), which encodes a transcriptiona

49 In Drosophila, Cubitus interruptus (Ci), which mediates hedgehog signal

50 GLI3 is homologous to Drosophila Cubitus interruptus (Ci), which regulates the patched (p

51 ion of the zinc finger transcription factor, Cubitus interruptus (Ci), while other studies suggest a

52 thought to involve the segment polarity gene cubitus interruptus (ci).

53 o by regulating the stability of full-length Cubitus interruptus (Ci).

54 te for the Hh-dependent transcription factor cubitus interruptus (Ci).

55 nase Fused (Fu) and the transcription factor Cubitus interruptus (Ci).

56 pathway, including the transcription factor Cubitus interruptus (Ci).

57 iscs by regulating the transcription factor, Cubitus interruptus (Ci).

58 ting the pathway's transcriptional effector, Cubitus interruptus (Ci).

59 onal regulation of the transcription factor, Cubitus interruptus (Ci).

60 ifunctional transcriptional mediator, called Cubitus interruptus (Ci).

61 ase Fused (Fu), and the transcription factor Cubitus interruptus (Ci).

62 ffecting the expression of an ato activator, Cubitus interruptus (Ci).

63 ase Fused (Fu), and the transcription factor Cubitus interruptus (Ci).

64 tes a signal transduction pathway regulating Cubitus interruptus (Ci).

65 ying the activity of the DNA-binding protein Cubitus interruptus (Ci).

66 ecifically activated by exogenously supplied Cubitus interruptus (Ci).

67 moothened (Smo) and the transcription factor Cubitus interruptus (Ci).

68 of the Hedgehog pathway transcription factor cubitus interruptus (Ci)/Gli by Cul3-Hedghog-induced MAT

69 that shares high levels of homology with the Cubitus interruptus (Ci)/Gli family of proteins.

70 edgehog (Hh) signaling pathway by inhibiting Cubitus interruptus (Ci)/Glioma-associated oncogene homo

71 by preventing proteolysis of the full-length Cubitus interruptus (Ci-155) transcriptional activator t

72 in ligase that is likely to act by targeting Cubitus interruptus and an unknown activator of hedgehog

73 conserved zinc finger domain with Drosophila Cubitus interruptus and are believed to function as tran

74 sion induced Hedgehog targets by stabilizing Cubitus interruptus and inducing decapentaplegic.

75 Specifically, engrailed and cubitus interruptus are expressed in complementary domai

76 a repressor form of the transcription factor Cubitus interruptus can block decapentaplegic misexpress

77 s the Hedgehog signal transduction component Cubitus interruptus for degradation by Cullin-3 and the

78 signaling from HH by governing access of the cubitus interruptus protein to the nucleus.

79 discs causes the accumulation of full-length Cubitus interruptus protein, but not of Smoothened, in b

80 ehog, patched, decapentaplegic, wingless and cubitus interruptus) are expressed in analogous patterns

81 latent cytoplasmic transcription factor Ci (Cubitus interruptus).

82 ation of Hedgehog (Hh) target genes requires Cubitus interruptus, a 155 kDa cytoplasmic zinc finger p

83 Roc1a mutant cells hyperaccumulate Cubitus interruptus, a transcription factor that mediate

84 a zinc-finger protein related to Drosophila cubitus interruptus, and Alx4(tm1rwm), a targeted null m

85 s receptor Patched, the transcription factor Cubitus interruptus, and the engrailed target gene that

86 Among them, hedgehog, patched, smoothened, cubitus interruptus, branchless, breathless, sprouty, de

87 ng the proteolytic processing of full-length Cubitus interruptus, Ci (Ci155), to generate a truncated

88 nce between repressor and activator forms of Cubitus interruptus, CiR and CiA.

89 a coactivator for the transcription factors Cubitus interruptus, Dorsal, and Mad, and as a cosuppres

90 er eukaryotic transcription factors, such as Cubitus interruptus, NF-kappa B and sterol regulatory el

91 of hedgehog downstream transcription factor cubitus interruptus, the Drosophila homologue of vertebr

92 e that unlike the results seen with Gli3 and Cubitus Interruptus, the fly homolog of Gli, only a mino

93 An important gene epistatic to hedgehog is cubitus interruptus, which encodes the fly homolog of a

94 oundary between the engrailed-expressing and cubitus interruptus-expressing domains, indicating that

95 ferent functions of their Drosophila homolog cubitus interruptus.

96 ity and activity of the transcription factor Cubitus interruptus.

97 naling through transcriptional repression of cubitus interruptus.

98 Smoothened and the transcriptional effector Cubitus interruptus.

99 ion of developmental genes like engrailed or cubitus interruptus.

100 ludes Fused, Costal, Suppressor of Fused and Cubitus interruptus.

101 gnaling pathway regulate a target other than Cubitus interruptus.

102 wing and leg by regulating the expression of Cubitus interruptus.

103 Hedgehog-dependent transcriptional regulator Cubitus interruptus.

104 i family are homologs of the Drosophila gene cubitus interruptus.

105 The Drosophila GLI protein, Cubitus interuptus (Ci), regulates segment polarity and

106 are zinc finger genes related to Drosophila cubitus interuptus, a component of the hedgehog signal t

107 heart and renal abnormalities, micrognathia, cubitus valgus, high-arched palate, short metacarpals an