ライフサイエンスコーパス: culture cell

1 ator Chorion factor 2 in flies and in tissue-culture cells.

2 manipulated to apply hemodynamic loading to culture cells.

3 he effects of FMNL3 suppression in mammalian culture cells.

4 reduced the AAPH pro-oxidant capacity in co-culture cells.

5 ructures containing the small GTPase Rab8 in cultured cells.

6 ,000-fold MECP2 up-regulation from the Xi in cultured cells.

7 lpha MAPK-induced BACE1 protein reduction in cultured cells.

8 nd stoichiometry in rat liver microsomes and cultured cells.

9 ently tagged clathrin coat components within cultured cells.

10 racellular vimentin and keratin filaments in cultured cells.

11 o 0.9 Hz after stimulation with 30 mM KCl in cultured cells.

12 ) strain A2MC2 induces type I interferons in cultured cells.

13 resistant to chemotherapeutic agents than 2D-cultured cells.

14 istance against random mutation was shown in cultured cells.

15 sed LRRK2-induced cytoplasmic aggregation in cultured cells.

16 HERV-K ENV imparts broad species tropism in cultured cells.

17 h mechanisms similar to those established in cultured cells.

18 expressed in adult Muller glia increased in cultured cells.

19 2 plays in its localization and stability in cultured cells.

20 system can restrict the JCPyV life cycle in cultured cells.

21 ormation in vivo, in contrast to findings in cultured cells.

22 ow yield functional folding of cone PDE6C in cultured cells.

23 7 reverse HOXC10-mediated drug resistance in cultured cells.

24 pig, ferret, and rabbit and in two types of cultured cells.

25 n and cell boundaries is a common feature of cultured cells.

26 lity and inhibitory activities reported with cultured cells.

27 ne expression patterns and protein levels in cultured cells.

28 ts Nf1 RasGAP activity in vivo as it does in cultured cells.

29 mimicked the effects of enzyme inhibition in cultured cells.

30 g of the regulation of glucose metabolism in cultured cells.

31 oxicity and reduced LRRK2 kinase activity in cultured cells.

32 d that of infectious EBOV and MARV in tissue cultured cells.

33 ortening upon long-term chemical exposure in cultured cells.

34 lopmental time points, dissected tissues and cultured cells.

35 negatively regulate YAP1 activity in tissue-cultured cells.

36 in the same species, in tissue sections and cultured cells.

37 fficult to study because HBV does not infect cultured cells.

38 take of recombinant AAV serotype 2 (AAV2) in cultured cells.

39 tin (mHTT) mediates its nuclear exclusion in cultured cells.

40 type during serial amplification passages in cultured cells.

41 specificity observed in vivo was retained in cultured cells.

42 s, as evidenced in various animal models and cultured cells.

43 man renalase 3'-UTR (untranslated region) in cultured cells.

44 hesions, and active beta1-integrin levels in cultured cells.

45 ered and shown to inhibit virus infection in cultured cells.

46 vercome by adaptation of the virus in tissue-cultured cells.

47 n with sonically prepared cell-free virus in cultured cells.

48 a model that induces protein aggregation in cultured cells.

49 been able to overcome these blocks in tissue-cultured cells.

50 y compound glycosylation and growth phase of cultured cells.

51 rate of diversification can be controlled in cultured cells.

52 protein and lipid delivery to nascent NR in cultured cells.

53 netic, genomic or other biological assays in cultured cells.

54 -1 in vitro and inhibits MOAP-1 stability in cultured cells.

55 egy of serial passage in nonhost animals and cultured cells.

56 en used to transfer constructs directly into cultured cells.

57 mes modulates the length of primary cilia in cultured cells.

58 e most potent ones were not acutely toxic to cultured cells.

59 ies of the PSP extracts were investigated in cultured cells.

60 re is much lower in human neurons than other cultured cells.

61 docin through cis- and trans-associations in cultured cells.

62 ects MKK and NLRP1B cleavage in vitro and in cultured cells.

63 processing of pri-mir-30c-1 in vitro and in cultured cells.

64 orylation and an increase in Abeta levels in cultured cells.

65 ring was classified by Hodgkin's criteria in cultured cells, 18% displayed tonic class 1 excitability

66 ent gene expression with 40-fold contrast in cultured cells, 32-fold in subcutaneous mouse tissue, an

67 tous structures, or rodlets, in human tissue culture cells, after gene transfer to adult mice, and ex

68 FBS-cultured cells also showed higher MsgA and NanA activity

69 both in Xenopus embryos and mammalian tissue culture cells, also impacts nuclear size.

70 ough LpdA is translocated inefficiently into cultured cells, an L. pneumophila DeltalpdA mutant displ

71 We show that 'EC-tagging' occurs in tissue culture cells and Drosophila engineered to express CD an

72 fied with AtMSI4 from A. thaliana suspension culture cells and identified by liquid chromatography-ma

73 gy to measure microtubule assembly in tissue culture cells and Xenopus egg extracts using two-photon

74 assembly, we combined experiments in tissue culture cells and Xenopus laevis egg extracts with a mat

75 the RNAs synthesized in abortively infected cultured cells and a human skin lesion by next-generatio

76 thermore, FBS transcripts can be taken up by cultured cells and affect the results of highly sensitiv

77 irected mutagenesis, mouse inoculation (from cultured cells and after cohabitation), monitoring of ba

78 ANGPTL2 can increase NOTCH activation in cultured cells and ANGPTL receptor interacted with NOTCH

79 ction of monogenic neuromuscular diseases in cultured cells and animal models.

80 With demonstrated utility in both cultured cells and animals, this mRNA delivery technolog

81 ent ~70-nanometer lateral resolution in both cultured cells and brain tissue, performing three-color

82 Following translocation into cultured cells and clustering by intimin, Tir Y474 is ph

83 ted LPS-induced paracellular permeability in cultured cells and enhanced expression of the adherens j

84 e exhibiting Cl-13 wild-type-like fitness in cultured cells and immunocompromised mice.

85 down-regulated were assessed for function in cultured cells and in a transgenic mouse.

86 ral genome promote viral RNA accumulation in cultured cells and in animal models of HCV infection.

87 hondrial and nuclear translocation of p53 in cultured cells and in APP/PS1 mice.

88 Hypoxia induced expression of KIT in cultured cells and in human colon tumor xenografts and t

89 2O3 exposure increased MTHFD1 SUMOylation in cultured cells and in in vitro SUMOylation reactions, an

90 llel with enhanced mitochondrial function in cultured cells and in leukocytes extracted from healthy

91 e to elevated beta-hydroxybutyrate levels in cultured cells and in livers from mice subjected to prol

92 logical and immunological characteristics in cultured cells and in mice.

93 T promoted SiO2 NP-induced apoptosis both in cultured cells and in mouse lung tissue.

94 In cultured cells and in samples from patients, HEV produce

95 In cultured cells and in transgenic mice, deficiency in end

96 its efficacy in blocking HCV replication in cultured cells and in treatment of patients with HCV inf

97 sphorylated downstream of AngII signaling in cultured cells and in vitro by PKC and PKA.

98 nscriptionally regulated by SKP2 in vitro in cultured cells and in vivo in mouse models.

99 dented telomere-specific DDR inactivation in cultured cells and in vivo in mouse tissues.

100 (G93A) uncovers a survival defect ex vivo in cultured cells and in vivo in tissues lacking Aptx.

101 rties of FABP5-expressing carcinoma cells in cultured cells and in vivo.

102 Loss of function in cultured cells and in zebrafish unexpectedly leads to in

103 broadly localized to the plasma membrane of cultured cells and intact blood vessels in the inner ret

104 as well as single-molecule precision in both cultured cells and intact brain tissue.

105 We noted specific subsets of RBPs in cultured cells and leaves and a comparison of Arabidopsi

106 dard 96-well plate with the ability to image cultured cells and membrane-bound microbeads in twelve i

107 the mitochondrial oxygen consumption rate of cultured cells and mice.

108 nd identification of sialoglycoproteins from cultured cells and model organisms.

109 Using cultured cells and mouse skeletal muscle, we show that T

110 of the protein triggers TDP-43 pathology in cultured cells and mouse skeletal muscle, which can be c

111 expressed ribosomal protein genes in single cultured cells and mouse thymus sections, revealing cell

112 hundreds of ADP-ribosylated proteins in both cultured cells and mouse tissues.

113 e feedback loop of the Hippo pathway in both cultured cells and mouse tissues.

114 Both cultured cells and mouse xenografts grow in an environme

115 e show that pALT(INK4a/b) is present in both cultured cells and naked mole rat tissues but is absent

116 lation and silencing upon differentiation in cultured cells and native epiblast.

117 Eya-So transcriptional output in vivo and in cultured cells and on meta analysis of their chromatin o

118 pproximately 7-kDa cytoplasmic C terminus in cultured cells and purified from Escherichia coli The al

119 ion of GLUT4, MEF2A, PGC-1alpha and HDAC5 in cultured cells and skeletal muscle of Wistar rats.

120 We use different types of animal tissues and cultured cells and test the performance of the method un

121 diates aggregation of otherwise non-adherent cultured cells and that loss of Ihog activity disrupts w

122 p to 4-fold, as shown by molecular assays in cultured cells and the use of a fluorescent reporter in

123 d on the introduction of random mutations in cultured cells and the use of nuclear transfer to genera

124 tion and RNA dynamics has been successful in cultured cells and tissues of vertebrates but is challen

125 LCMV/TransS showed slower growth kinetics in cultured cells and was highly attenuated in vivo in a mo

126 sS exhibited reduced viral multiplication in cultured cells and was highly attenuated in vivo while c

127 protective against mitochondrial toxicity in cultured cells and zebrafish models.

128 0.3 Hz, respectively, for adrenal slices and cultured cells) and increased up to 0.9 Hz after stimula

129 il shortening and mRNA degradation in tissue culture cells, and we detect a reduced number of Mad and

130 ibe key findings in human postmortem brains, cultured cells, and animal models of disease that suppor

131 expression of adipocyte marker genes in the cultured cells, and shRNA knockdown of PPFP eliminated t

132 dolosa induced a robust cytokine response in cultured cells, and this effect was dependent on the fla

133 Influenza vaccines propagated in cultured cells are approved for use in humans, but their

134 and expand Ag-specific memory B cells; these cultured cells are highly effective in presenting Ag to

135 es, but differences in CA between tumors and cultured cells are uncharacterized.

136 Cultured cells are widely used in mechanistic studies of

137 We found that overexpression of PKCgamma in cultured cells, as well as in vitro incubation of PKCgam

138 downstream signaling, and inhibit growth of cultured cells, as well as recruit immune effector cells

139 Similar rings are observed in Xenopus tissue culture cells at a lower frequency but are enriched in c

140 mechanodynamics of epithelial monolayers by culturing cells at an air-liquid interface.

141 In cultured cells, ATF4 induces transcriptional expression

142 Experiments in cultured cells, brain slices, and in living mice demonst

143 mpromises bipolar spindle assembly in tissue culture cells but not in X. laevis egg extracts.

144 ffected the kinetics of VEEV accumulation in cultured cells but strongly inhibited its pathogenesis i

145 C) exhibited Cl-13-like growth properties in cultured cells, but in contrast to Cl-13, rCl-13/LASV-GP

146 RNA and lipids in single organelles of live cultured cells by biomolecular component analysis using

147 pacity for efficient productive infection of cultured cells by herpes simplex virus 1 has made it a p

148 he IP receptor in podocytes was confirmed in cultured cells by immunoblotting and quantitative real-t

149 ation of HuR and target RNAs in vitro and in cultured cells by interfering with the binding of HuR to

150 Here we demonstrate this approach in cultured cells by monitoring a viral infection and the c

151 gical inhibition of Hsc70 ATPase activity in cultured cells by the drug VER155008 prevents this chape

152 e show that PIM1 is modified in vitro and in cultured cells by the Small ubiquitin-like modifier (SUM

153 However, cultured cells can acquire resistance to K5Is, indicativ

154 Next, we show that the damping rate of cultured cells can be changed in a dose-dependent fashio

155 Knockdown of LACTB2 in cultured cells caused a moderate but significant accumul

156 In contrast, recent work that employed cultured cells claimed that only PrP(C) with sialylo-GPI

157 2 genes could be recovered and maintained in culture, cell clones with simultaneously inactive GLT25D

158 y more embedded ribonucleotides than that of cultured cells, consistent with the high ratio of ribonu

159 t displayed altered substrate specificity in cultured cells, consistent with the idea that SUMOylatio

160 mal aggregation in NHFs-cultured cells, MWFs-cultured cells contain more and bigger lysosomal accumul

161 The cultured cells contained HPV-16, formed colonies in soft

162 sion of contractile smooth muscle markers in cultured cells could be partially or completely represse

163 ious studies predate the infectious HCV cell culture (cell culture-derived HCV [HCVcc]) system.

164 ansgenic Drosophila, providing evidence that cultured cell cytoneme analysis is predictive of in vivo

165 Here, we introduce a fixation method whereby cultured cell cytonemes can be preserved for imaging stu

166 e testing methodologies, including toxigenic culture, cell cytotoxicity, antigen detection, and, more

167 n results in premature ciliary resorption in cultured cells dependent on function of the tubulin deac

168 For example, SARS-CoV infection of cultured cells depends on endosomal acid pH-dependent pr

169 irmed the cell-based observations using both cultured cell-derived and patient-derived xenograft stud

170 ting embryonic tissue and in differentiating culture cells, despite these genes being located on diff

171 Asc restoration in cultured cells dramatically altered their stress respons

172 beta oligomers (oAbeta) from hAPP-expressing cultured cells, EE prevented several morphological featu

173 hromosome could be selectively eliminated in cultured cells, embryos, and tissues in vivo.

174 Experiments in cultured cells established biochemical assays for disass

175 Recently, cultured cell experiments identified human MX2 as a key

176 hat are elicited by brief pulses of light to cultured cells expressing melanopsin and to neurons-expr

177 In cultured cells, expression of both the mutant SDR9C7 pro

178 idarum, a starter population was passaged in cultured cells for 28 generations without standard infec

179 We demonstrate that cultured cells form multiple nanotubes that mediate inte

180 Cultured cells from both diseases have similar sensitivi

181 We cultured cells from healthy gastric tissues, single-sort

182 In mice lacking CPEB1 and in cultured cells from which CPEB has been depleted, random

183 In cultured cells, Fucci(CA) produced a sharp triple color-

184 Work in cultured cells has established a wide array of functions

185 Genetic engineering of model organisms and cultured cells has for decades provided important insigh

186 Human tissue culture cells have long been a staple of molecular and c

187 Although cultured cells have facilitated investigations of lncRNA

188 While studies of cultured cells have led to new insights into biological

189 Consistent with the results in cultured cells, hepatic levels of Insig-2 mRNA were enha

190 detected for 14 days after MOCV infection of cultured cells; however, there was little change in the

191 roteins and protected mucus-producing tissue culture cells in vitro.

192 HIF target gene expression both in mice and cultured cells in a manner that was at least in part ind

193 hase kinase-3beta inhibitor for 3 days, then cultured cells in renal epithelial growth medium to indu

194 organization and dynamics are controlled in cultured cells in vitro However, our understanding of mi

195 ibrils display cytotoxic capabilities toward cultured cells in vitro, with oligomers producing elevat

196 However, emerging evidence suggests that culturing cells in ambient air, or "normoxia," is far fr

197 In this study, we demonstrate that culturing cells in different physical environments, stif

198 These effects can be recovered by culturing cells in the presence of a ROS quencher or in

199 ng machines have been studied extensively in cultured cells; in contrast, remarkably little is known

200 requirements to achieve lytic replication in cultured cells included (i) either in vitro cultures of

201 Sterol depletion in cultured cells increased flux through the Bloch pathway,

202 ormal protein distributions were reversed in cultured cells incubated with SB216763, a small molecule

203 ce for deoxyribonucleotides, and analysis of cultured cells indicates that mammalian mitochondrial DN

204 Overexpression of Aurora B in cultured cells induces defective chromosome segregation

205 , ruzasvir, velpatasvir, and pibrentasvir in cultured cells infected with HCV recombinants expressing

206 In cultured cells, infectivity and cytokine induction were

207 encephalitis in mice, and its replication in cultured cells is inhibited by the zinc finger antiviral

208 RQC recruitment to the ER in cultured cells is stimulated by translation stalling.

209 Overexpression of CK1epsilon in cultured cells led to increased tau phosphorylation at m

210 nic brain tissue, as well as in human tissue culture cell lines using RNA in situ hybridization.

211 ion, rCl-13(GPC/VGKS) grew to high titers in cultured cell lines and in immunodeficient mice.

212 Studies with cultured cell lines and primary embryonic cells showed t

213 nthetic yeast centromeric plasmids (YCps) to cultured cell lines at rates similar to that of 12 kb YC

214 studying the effect of anti-cancer drugs in cultured cell lines by monitoring phosphatidylserine tra

215 to produce vaccines by adaptation of ASFV to cultured cell lines have been made.

216 We further cultured cell lines specific for four SIV-derived epitop

217 We have shown previously in cultured cell lines that Bok interacts strongly with ino

218 We found that in cultured cell lines, FAM92A colocalizes with Cby1 at the

219 sed chromatin organization studies have used cultured cell lines, limiting their generalizability.

220 or 16,698 single cells from a combination of cultured cell lines, primate frontal cortex tissue and t

221 In cultured cell lines, the EXT1 and EXT2 enzymes, initiati

222 ariations in cell-cycle requirements between cultured cell lines, we generated knockouts across cell

223 as project for 11 punctate proteins in three cultured cell lines.

224 rter plasmids into Huh7, BNL-1ME, and HEK293 cultured cell lines.

225 e explicitly demonstrate this exchange by co-culturing cell lines with distinct mtDNA haplotypes.

226 on gene expression have been well studied in cultured cells, little is known about its functions in i

227 In cultured cells, loss of JAM-A caused an approximately 30

228 Serum steroids and cultured cell media androgens were measured with liquid

229 As have made targeted mutagenesis routine in cultured cells, mice, zebrafish and other model systems.

230 s (1.6%, p<0.01), and were higher for the co-culture cell model compared to Caco-2 cells (p<0.01).

231 ro digestion, cellular uptake (Caco-2 vs. co-culture cell model: Caco-2:HT-29-MTX (90:10%) and coloni

232 Using a cultured cell model of erythroid differentiation, deplet

233 ate partners interacted both in vitro and in cultured cell models.

234 tochondrialand lysosomal aggregation in NHFs-cultured cells, MWFs-cultured cells contain more and big

235 In zebrafish and cultured cells, NCOA4 plays an essential role in erythro

236 and the basal body in different tissues and cultured cells of Drosophila melanogaster, highlighting

237 Cultured cells of Eschscholzia californica (Papaveraceae

238 -active frustule biosilica was isolated from cultured cells of the marine diatom Pinnularia sp. and f

239 Expression in cultured cells of these APOL1 risk variants, commonly re

240 ia physically interact and cross-regulate in cultured cells, our work indicates that a conserved EXC-

241 In cultured cells, overexpressed Smad3 is sufficient to ind

242 Functional analysis in cultured cells overexpressing FLAG-tagged wild-type or m

243 ased the incidence of inclusion formation in cultured cells overexpressing P23H rod opsin, and increa

244 Furthermore, in cultured cells, overexpression of N22A mutant OTUB1 impa

245 tial for binding to beta-Catenin in vitro In cultured cells, phosphorylation of specific serine resid

246 also show that association rates measured in cultured cells predict the extent of internalization of

247 s capable of interaction with poly(A) RNA in cultured cells, primarily mediated by the N-terminal reg

248 hitectures and similar fine structures to 2D-cultured cells, providing a pathway to enable our unders

249 In cultured cells, Rbpr2 localized to membranes and promote

250 In contrast, overexpression of SORLA in cultured cells reduced the abundance of endogenous calci

251 observe that the baseline state of untreated cultured cells relative to untreated rat liver shows str

252 Cultured cells repopulated tracheal scaffolds in a heter

253 However, mutagenized cultured cells require cloning to yield homogeneous popu

254 Cultured cells require the actions of growth factors to

255 itro, depletion of FL2 from mammalian tissue culture cells results in a more than twofold increase in

256 WH by siRNA in Drosophila, mouse, and human cultured cells results in DNA damage with strand breaks

257 iption (TPRT) and mobilized efficiently in a cultured cell retrotransposition assay.

258 phenotyping analysis of FGF-10 mobilized and cultured cells revealed expression of the MSC markers CD

259 xpressed functional VAP-1, and evaluation of cultured cells revealed that sVAP-1 promotes leukocyte m

260 In cultured cells, RGNs on-target editing activity had been

261 HSV infection in these cultured cells shows the properties expected for a laten

262 Here, we report that in SPECC1L-knockdown cultured cells, staining of canonical adherens junction

263 35Pro]) and the REEP6.1 frameshift mutant in cultured cells suggest that these changes destabilize th

264 d from host cells in response to bacteria in cultured cell systems and in the intestine in vivo Uric

265 This is observed in cultured cell systems, as well as in clinical trials in

266 In cultured cells, tacrolimus inhibited dephosphorylation o

267 In cultured cells, TBK1 associates with and activates mTORC

268 ce from experiments conducted in vivo and in cultured cells that indicates aldosterone and vasopressi

269 lated in Abcc5(-/-) tissues were depleted in cultured cells that overexpressed human ABCC5.

270 ignificantly decreased the viral RNA load in cultured cells that were infected with viruses of the fa

271 In cultured cells, the mutations reduced the DNA binding af

272 s by analyzing LZA element function in human cultured cells; the LZA element-mediated transcriptional

273 In cultured cells, this capacity is tightly aligned to phos

274 t Pik3ca induces centrosome amplification in cultured cells (through a pathway involving AKT, ROCK an

275 While smFISH has been developed for culture cells, tissue sections and whole-mount invertebr

276 inolevulinic acid (ALA) treatment of mice or cultured cells to bypass the rate-limiting enzyme in hep

277 lain elevated CA in vivo because exposure of cultured cells to hypoxia or mimicking hypoxia pharmacol

278 Sample preparation takes 3 d from cultured cells to pooled libraries.

279 well-established model systems ranging from cultured cells to simple organisms and to mice and plant

280 In this study, from supernatant of culture cells transfected with DNAs of an Autographa cal

281 In cultured cells, treatment with sunitinib and erlotinib,

282 saying short CREs in a limited repertoire of cultured cell types.

283 ken together, these results demonstrate that culturing cells under hyperoxic conditions reduces their

284 with PRC1, PRC2, and H3K27me3 in embryos and cultured cells using ChIP-seq (chromatin immunoprecipita

285 sociated AAA+ ATPase VPS4 on EV release from cultured cells using two methods for EV recovery, differ

286 pair resolution during HIV-1 replication in cultured cells using vectors that force template switchi

287 y (STORM) to Xenopus egg extracts and tissue culture cells, we report various distribution patterns o

288 In cultured cells, we found that corin activation was inhib

289 High levels of RSV F expression in cultured cells were observed with rHPIV1-C(Delta170)-F1,

290 infection and GP-mediated membrane fusion in cultured cells were remarkably suppressed by treatment w

291 latory activity of GPC6 was also observed in cultured cells, where this GPC increased the binding of

292 nge at the frequency of 5% in primary tissue culture cells, whereas higher levels were seen in severa

293 induced aggregation of alpha-syn*A53T-YFP in cultured cells, whereas none of six Parkinson's disease

294 describes how to identify the active RBPs in cultured cells, whereas this Protocol Extension also ena

295 as validated for targeting lysosomes in live cultured cells, which enabled identification and subsequ

296 ectron battery by stimulating a monolayer of cultured cells, which fluoresces a calcium ion wave at a

297 antly increased MMPs expression in 3D vs. 2D cultured cells, while pharmacological inhibition of MMPs

298 cifically addressed whether nonproliferating cultured cells will sense the presence of microgravity i

299 Importantly, treatment of porcine cultured cells with Ad5-poIRF7/3(5D) inhibited the repli

300 ools for the efficient delivery of mRNA into cultured cells would advance many areas of research, and