ライフサイエンスコーパス: cuniculi

1 as infected with both E. intestinalis and E. cuniculi.

2 nents of these organelles in Encephalitozoon cuniculi.

3 tive immune response against Encephalitozoon cuniculi.

4 ficant sequence similarity to proteins in E. cuniculi.

5 chizosaccaromyces pombe) and Encephalitozoan cuniculi.

6 r had positive serologic test results for E. cuniculi.

7 the microsporidian parasite Encephalitozoon cuniculi.

8 s (CTL) in survival of mice infected with E. cuniculi.

9 pecies-specific primers for E. hellem and E. cuniculi.

10 n intestinalis (2.3 Mbp) and Encephalitozoon cuniculi (2.9 Mbp) revealed massive gene losses and redu

11 0 tpr homologs in Treponema paraluiscuniculi Cuniculi A strain and determined their sequence architec

12 unclassified Fribourg-Blanc isolate, and the Cuniculi A strain of T. paraluiscuniculi.

13 (Bosnia strain), Treponema paraluiscuniculi (Cuniculi A, H, and K strains), and a little-characterize

14 Encephalitozoon cuniculi, a microsporidial species most commonly recogni

15 Hence, E. cuniculi, a minimal eukaryotic cell that has removed all

16 The inference is that E. cuniculi also uses these proteins to steal ATP from its

17 during murine infection with Encephalitozoon cuniculi, an intracellular parasite, was observed.

18 ut also had cross-reactivity to spores of E. cuniculi and E. intestinalis.

19 his study, we show that both Encephalitozoon cuniculi and Encephalitozoon intestinalis are preferenti

20 rikingly similar to those of Encephalitozoon cuniculi and Encephalitozoon intestinalis in both form a

21 scence histograms showed that rabbit anti-E. cuniculi and rabbit anti-E. intestinalis sera were react

22 ents for the microsporidians Encephalitozoon cuniculi and Trachipleistophora hominis.

23 Encephalitozoon species (E. intestinalis, E. cuniculi, and E. hellem).

24 oridian spores of Encephalitozoon hellem, E. cuniculi, and E. intestinalis were propagated in axenic

25 from the eukaryotic pathogen Encephalitozoon cuniculi bound to tryptophan, a HisRS from Burkholderia

26 ochondrion and host has been subverted in E. cuniculi, by reductive evolution and analogous gene repl

27 of the N-terminal domain of Encephalitozoon cuniculi Cdc27 (Cdc27(Nterm)), revealing a homo-dimeric

28 n solution, and abolishes the capacity of E. cuniculi Cdc27 to complement Saccharomyces cerevisiae Cd

29 tect naive CD8(-/-) mice against a lethal E. cuniculi challenge.

30 the microsporidian parasite Encephalitozoon cuniculi consists of 15 heptad repeats, which approximat

31 Encephalitozoon cuniculi continues to pose a problem for immunocompromis

32 As a result, a new component of the E. cuniculi developing spore wall was identified.

33 lysis provides a basis for distinguishing E. cuniculi, E. hellem, and E. intestinalis in clinical spe

34 med 3B6, strongly recognized Encephalitozoon cuniculi, E. hellem, and E. intestinalis.

35 cleotide probes specific for Encephalitozoon cuniculi, E. hellem, and Encephalitozoon (Septata) intes

36 iaDB contains the genomes of Encephalitozoon cuniculi, E. intestinalis and E. bieneusi.

37 l and structural analyses of Encephalitozoon cuniculi Ecm1, a prototypal cellular cap methyltransfera

38 challenged with the parasite Encephalitozoon cuniculi, effector CD8+ T cell survival and polyfunction

39 es: Enterocytozoon bieneusi, Encephalitozoon cuniculi, Encephalitozoon hellem, and Encephalitozoon in

40 t the intracellular parasite Encephalitozoon cuniculi encodes a complete mRNA capping apparatus consi

41 Here we show that E. cuniculi encodes a minimized 411-aa Fcp1-like protein (E

42 The E. cuniculi genome does contain four genes for an unrelated

43 genome of the microsporidian Encephalitozoon cuniculi has lost all of its genes for MCF proteins.

44 E. cuniculi has the smallest sequenced eukaryotic genome, 2

45 uman E. cuniculi isolate was identical to E. cuniculi III, which had been isolated only from domestic

46 PCR tests were developed to differentiate E. cuniculi in clinical samples.

47 rime an IEL response against Encephalitozoon cuniculi in vitro.

48 neration of CD8(+) T-cell immunity during E. cuniculi infection and the cytokines involved in this pr

49 gamma(delta) T cells were susceptible to E. cuniculi infection at high challenge doses.

50 In the current study, we demonstrate that E. cuniculi infection causes strong Toll-like receptor 4 (T

51 imals, CD4(-/-) mice were able to resolve E. cuniculi infection even at a very high challenge dose (5

52 he present study, immune response against E. cuniculi infection in CD4(+) T-cell-deficient mice was e

53 ta obtained in these studies suggest that E. cuniculi infection induces a strong and early CD8+ T res

54 an IFN-gamma-mediated protection against E. cuniculi infection that is independent of NO production.

55 E. cuniculi infection thus offers an example of an intracel

56 response generated in the gut after oral E. cuniculi infection was evaluated.

57 The role of gamma(delta) T cells against E. cuniculi infection was further evaluated by using gene-k

58 Ag-specific CD8+ T cell immunity against E. cuniculi infection was noted in delta(-/-) mice.

59 ntigen-specific CD8(+) T-cell response to E. cuniculi infection was observed in CD4(-/-) mice (precur

60 lpha subset of IEL in response to an oral E. cuniculi infection was observed.

61 T-cell response in CD4(-/-) mice against E. cuniculi infection was studied.

62 it greater susceptibility to Encephalitozoon cuniculi infection, and their ability to evoke an Ag-spe

63 Effectively, after Encephalitozoon cuniculi infection, CD11b(-) CD8(+) DC were activated in

64 tical for protection against Encephalitozoon cuniculi infection.

65 nt did not identify factors for suspected E. cuniculi infection.

66 induction of CD8+ T-cell immunity against E. cuniculi infection.

67 l priming of CD8+ T cell immunity against E. cuniculi infection.

68 tant role in defense against Encephalitozoon cuniculi infection.

69 Encephalitozoon cuniculi infects a wide range of mammalian hosts.

70 Encephalitozoon cuniculi is a protozoan parasite that has been implicate

71 Encephalitozoon cuniculi is commonly found in domestic rabbits and roden

72 it is able to grow in vitro, Encephalitozoon cuniculi is currently the best-studied microsporidian.

73 of a recently cultured human Encephalitozoon cuniculi isolate was analyzed by gene amplification and

74 The human E. cuniculi isolate was identical to E. cuniculi III, which

75 These E. cuniculi isolates also differed from one another in the

76 In addition, some E. cuniculi isolates had heterogeneous copies of the SWP-1

77 uence analysis of the PTP gene divided 11 E. cuniculi isolates into three genotypes in congruence wit

78 o-locates with mitochondrial Hsp70 to the E. cuniculi mitosome.

79 The Encephalitozoon cuniculi mRNA cap (guanine N-7) methyltransferase Ecm1 h

80 chain reaction testing were positive for E. cuniculi of genotype III in each recipient; the organism

81 crophages were infected with Encephalitozoon cuniculi or Encephalitozoon intestinalis, and the recrui

82 rown Encephalitozoon hellem, Encephalitozoon cuniculi, or Vittaforma corneae or with Enterocytozoon b

83 protein interactions of the Encephalitozoon cuniculi polar tube proteins (EcPTPs).

84 ormatic investigation of the Encephalitozoon cuniculi proteome.

85 Mice infected with E. cuniculi secrete significant levels of gamma interferon

86 mples reacted with anti-E. hellem or anti-E. cuniculi sera, nor were they amplified with species-spec

87 ) cultures from knockout mice pulsed with E. cuniculi spores were unable to develop a robust CD8(+) T

88 harvested) and dead (boiled) Encephalitozoon cuniculi spores.

89 s, and E. hellem, as well as Encephalitozoon cuniculi, spores in fecal samples and is a useful tool f

90 ents in Russia and the first detection of E. cuniculi strain II in a human.

91 ht new dog isolates were characterized as E. cuniculi strain III by use of molecular methods.

92 arasites to a species level and to define E. cuniculi strains I, II, and III.

93 he existence of functional APC/C genes in E. cuniculi, the evolutionarily conserved dimeric propertie

94 In E. cuniculi, the iron (frataxin) and sulphur (cysteine desu

95 consistent with this hypothesis, all four E. cuniculi transporters can transport ATP, and three of th

96 ot Encephalitozoon hellem or Encephalitozoon cuniculi was confirmed in 6 of 8 mammalian stool samples

97 Encephalitozoon cuniculi was detected in three patients: one with strain

98 In this study, the genetic diversity of E. cuniculi was examined at the polar tube protein (PTP) an

99 The proteins of E. cuniculi were compared with a previously characterized s

100 donors protected SCID mice infected with E. cuniculi, whereas administration of CD8(+) T cells from

101 f effector CD8(+) T-cell immunity against E. cuniculi, which is critical for host survival.

102 ted in vivo activity against Encephalitozoon cuniculi, with prolonged survival and the prevention of