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1 thritis is a common, complex disease with no curative therapy.
2 ctory prostate cancer, for which there is no curative therapy.
3 , and currently remains the only potentially curative therapy.
4 gressive primary brain tumor with no current curative therapy.
5  only those men with significant cancers for curative therapy.
6 atedly interpreted as providing evidence for curative therapy.
7 lar pancreatic cancer, which lacks effective curative therapy.
8 ith stem cell transplantation being the only curative therapy.
9 ith stem cell transplantation being the only curative therapy.
10 plantation is currently the only potentially curative therapy.
11 isease with high public health burden and no curative therapy.
12 in the abdomen, a characteristic that limits curative therapy.
13 an 85% of adults worldwide with no permanent curative therapy.
14 istant urothelial carcinoma has no uniformly curative therapy.
15 epresents a significant clinical obstacle to curative therapy.
16      Bone marrow transplantation is the only curative therapy.
17 applies to patients with MT-GCT treated with curative therapy.
18 nfected cells that persist after potentially curative therapy.
19  cell transplantation might be a potentially curative therapy.
20 e showing significant promise as potentially curative therapy.
21 r really have an opportunity for a potential curative therapy.
22 ents remains poor with short survival and no curative therapy.
23  the epileptogenic focus represents the only curative therapy.
24 ancer is notorious for recurrence even after curative therapy.
25 ading to limited availability of options for curative therapies.
26 taking decisions on efficient preventive and curative therapies.
27 tion of this cell population is required for curative therapies.
28 of virus cell entry and open new avenues for curative therapies.
29 /E7 vaccines already in clinical trials into curative therapies.
30 has produced limited clinical benefit and no curative therapies.
31 e and palliative care, and limited access to curative therapies.
32 th bladder cancer do not receive potentially curative therapies.
33  of retinal degeneration that currently lack curative therapies.
34 cer (NSCLC) being considered for potentially curative therapies.
35 ellular carcinoma (HCC) patients who receive curative therapies.
36 o address the unmet need for preventative or curative therapies.
37  problem in the United States; yet, the only curative therapy, a bone marrow transplant (BMT), is sel
38 ng ovarian cancer represent complications of curative therapies and/or underlying susceptibility stat
39 recurrent cervical carcinoma not amenable to curative therapy and at least one prior regimen in the m
40                   Treatment measures such as curative therapy and case isolation exert selective pres
41 as not required for immunologically specific curative therapy and induction of memory provided that a
42 fferences impact eligibility for potentially-curative therapy and prognosis.
43 ederal regulations require patients to forgo curative therapies, and they interpret phase I agents as
44 e on early stage tumor detection, receipt of curative therapy, and overall survival in patients with
45 vements in early tumor detection, receipt of curative therapy, and overall survival in patients with
46         JMML remains a disease for which few curative therapies are available other than myeloablativ
47  radiologists to detect smaller tumors, when curative therapies are most effective.
48                                              Curative therapies are most successful when cancer is di
49 is is important because effective, and often curative, therapies are available for many subtypes.
50              For both forms of XLP, the only curative therapy at present is allogeneic hematopoietic
51 nding of the tauopathies, there are still no curative therapies available.
52 ers are not yet treatable and/or are without curative therapies because of our limited understanding
53  transplantation (HCT) has been considered a curative therapy, but the procedure has inherent complic
54 riven proliferation of T-effector cells, but curative therapy can be achieved in nonconditioned hosts
55                                    Because a curative therapy can be offered to these patients (ie, b
56 ntify and treat more eligible candidates for curative therapy could be beneficial.
57 egenerative disorders for which no effective curative therapy currently exists.
58 f 11 patients (28%) who received potentially curative therapy died, compared with 62 of 71 patients (
59 stance within persisting tumor cells renders curative therapies elusive for the majority of women wit
60  myeloma is a B-cell malignancy for which no curative therapies exist to date, despite enormous resea
61                                              Curative therapy exists even in patients with resistant
62 mains a challenge to clinical medicine, with curative therapy experienced by a minority of patients.
63 ugh international clinical trials, effective curative therapies for about half of patients with sever
64 urpose of the study was to assess the use of curative therapies for hepatocellular carcinoma (HCC) in
65 ht enable the development of next-generation curative therapies for individuals with cancer.
66 gets for the development of preventative and curative therapies for Lyme disease.
67                  Current models predict that curative therapies for many cancers will require the eli
68 resent a path forward for the development of curative therapies for the majority of cancer patients.
69 en-specific regulatory T cells could provide curative therapies for these problems.
70        Currently, there are no preventive or curative therapies for this dominantly inherited disease
71             How dangerous does a potentially curative therapy for a fatal illness need to be before w
72 ic BM transplantation, and thereby provide a curative therapy for a wide spectrum of human diseases.
73       Mercaptopurine (MP) is the mainstay of curative therapy for acute lymphoblastic leukemia (ALL).
74 ensive research, but so far no preventive or curative therapy for AD is available, and clinical trial
75 mpared in patients who underwent potentially curative therapy for adenocarcinoma of the pancreatic he
76                         There is no accepted curative therapy for ATL.
77              Presently, there is no accepted curative therapy for ATL.
78          Presently, there is not an accepted curative therapy for ATL.
79              Currently, there is no accepted curative therapy for ATL.
80                                              Curative therapy for cancer patients with advanced-stage
81 ell transplantation (HCT) may offer the only curative therapy for certain life-threatening immune def
82  liver transplantation is currently the only curative therapy for chronic end-stage liver disease and
83 one marrow transplantation (BMT) is the only curative therapy for chronic myelogenous leukemia (CML),
84 marrow transplantation (BMT) offers the only curative therapy for chronic myelogenous leukemia.
85 c blood or marrow transplantation (BMT) is a curative therapy for chronic myeloid leukemia (CML).
86 geneic stem cell transplantation is the only curative therapy for chronic myeloid leukemia.
87 Despite intensive efforts in recent years, a curative therapy for cutaneous T-cell lymphoma (CTCL) ha
88                                              Curative therapy for diabetes mellitus mainly implies re
89 urvival outcomes between patients undergoing curative therapy for HCC in the background of NASH compa
90 y has become an integral part of potentially curative therapy for head and neck cancer and has been i
91 opoietic cell transplantation, a potentially curative therapy for hematologic diseases.
92  Reduced intensity has allowed a potentially curative therapy for hematologic malignancies to be offe
93 c stem cell (HSC) transplantation is used as curative therapy for hematologic malignancies.
94  blood and marrow transplantation (BMT) as a curative therapy for hematological malignancies lies in
95  bone marrow transplantation (allo-BMT) is a curative therapy for hematological malignancies, but is
96 transplantation (allo-HSCT) is a potentially curative therapy for hematological malignancies.
97 rgical excision remains the only potentially curative therapy for hepatic malignancies.
98 diofrequency ablation (RFA) is a potentially curative therapy for hepatocellular carcinoma (HCC).
99 atectomy is safe, effective, and potentially curative therapy for hepatocellular carcinoma.
100 ains the most effective and only potentially curative therapy for hilar cholangiocarcinoma.
101             Solid organ transplantation is a curative therapy for hundreds of thousands of patients w
102 es to evolve as an effective and potentially curative therapy for limited numbers of patients with re
103 tic stem cell transplantation is a potential curative therapy for malignant and nonmalignant diseases
104 c stem cell transplantation is a potentially curative therapy for many malignant and non-malignant he
105 ntation of cord blood provides a potentially curative therapy for many patients without a suitably hu
106 nd currently represents the only potentially curative therapy for metastatic colorectal cancer.
107                                Currently, no curative therapy for metastatic prostate cancer exists.
108 ietic cell transplantation (HCT) is the only curative therapy for MF.
109                               Traditionally, curative therapy for most renal cancers involved open ra
110 oietic stem cell transplantation is the only curative therapy for myelodysplasia (MDS).
111  stem cell transplantation (HCT) is the only curative therapy for myelodysplastic syndrome (MDS).
112 ansplantation (HSCT) is the only potentially curative therapy for myelofibrosis.
113 ellular immunotherapy (ACT) is a potentially curative therapy for patients with advanced cancer.
114 etic stem cell transplantation (HSCT) offers curative therapy for patients with hemoglobinopathies, c
115 ron-sparing surgery (NSS) provides effective curative therapy for patients with localized renal cell
116 etic cell transplantation offers potentially curative therapy for patients with myelodysplastic syndr
117                            HSCT represents a curative therapy for patients with MYSM1 deficiency.
118 lthough surgery remains the only potentially curative therapy for patients with primary GEP-NETs, oth
119                           PURPOSE Surgery is curative therapy for pediatric low-grade gliomas (LGGs)
120 neic bone marrow transplantation is the only curative therapy for PNH.
121 opoietic stem cell transplantation, the only curative therapy for SCD and Thal, is limited by the abs
122 c cell transplantation is, to date, the only curative therapy for SCD, but its application is limited
123 ransplantation (alloHCT) represents the only curative therapy for several hematologic malignancies, a
124                Additionally, HSCT has been a curative therapy for several nonmalignant hematologic di
125 e cyclophosphamide (Cy) has been promoted as curative therapy for severe aplastic anemia (SAA).
126                                     The only curative therapy for sickle cell disease (SCD) is alloge
127 one marrow transplantation (BMT) is the only curative therapy for sickle cell disease (SCD).
128 nib and, to date, there remains no effective curative therapy for systemic mastocytosis associated wi
129 ic cell transplantation provides potentially curative therapy for t-MDS, but additional improvements
130 se (NCDB), we examined patients who received curative therapy for the following sites: oral tongue, o
131 marrow transplantation is currently the only curative therapy for the hematopoietic complications of
132 murafenib response with the ultimate goal of curative therapy for the subset of melanoma patients wit
133 arrow transplantation remains the only known curative therapy for these patients and the use of reduc
134 e therapy does appear feasible and may offer curative therapy for those with refractory and relapsed
135 ment by islet transplantation is a potential curative therapy for type 1 diabetes.
136 cess of islet transplantation as a potential curative therapy for type 1 diabetes.
137 onfined to regional lymph nodes, there is no curative therapy for widely metastatic disease.
138                                Nevertheless, curative therapy has remained elusive for important path
139  transplantation (BMT) is currently the only curative therapy; however, toxic myeloablative precondit
140 ntial to vastly increase the availability of curative therapy in CLL while retaining a low treatment-
141 reatment paradigms, and deintensification of curative therapy is a current research focus for these p
142                                     The only curative therapy is allogeneic transplantation.
143                                           No curative therapy is available for malignant gliomas.
144                                           No curative therapy is currently available for AGU.
145 onal myeloid-disabling disorder for which no curative therapy is currently available.
146                             When potentially curative therapy is no longer an option, the patient, fa
147 rlier diagnosis, which may allow potentially curative therapy, is necessary.
148 ize, such that surgery, the only potentially curative therapy, is not possible.
149 n early stage are candidates for potentially curative therapies (local ablation, resection, or transp
150 tients, but the efficacy of this potentially curative therapy may be limited by poor persistence of T
151 ifferences in recurrence-free survival after curative therapy (median, 60 versus 56 months; P = 0.303
152 r stem cells is believed to be essential for curative therapy of cancers, but supporting evidence is
153 tegies besides Bcr-Abl kinase inhibition for curative therapy of CML.
154 alkylating agents have a central role in the curative therapy of many human tumors; yet, resistance t
155 c stem cell transplantation remains the only curative therapy of MF, but due to its associated morbid
156 ses, stem cell pathways must be targeted for curative therapy of Ph(+) leukemia.
157 ital anemias for which there is presently no curative therapy other than allogeneic hematopoietic ste
158                                    To obtain curative therapy, other effective agents, based on HL bi
159  62 of 71 patients (87%) who did not receive curative therapy (P = .0001).
160  in order to design safer and more effective curative therapy, particularly for children with SCID di
161                                           No curative therapy presently exists.
162 e (41.2% vs. 30.9%), or received potentially curative therapy (resection, transplantation), compared
163                               The absence of curative therapy results in lifelong carriage marked by
164                                              Curative therapy, thanks to insights into the molecular
165 vior, treatment coverage, and the effects of curative therapies that also block Plasmodium parasite t
166 ions with potential to reduce anti-Wolbachia curative therapy times to between one and two weeks.
167                               Among possible curative therapies, traditional antiretroviral therapy,
168                                        Novel curative therapies using genetic transfer of normal glob
169                                              Curative therapy was achieved with doses of 101M that di
170 mediate or high grade, for which no standard curative therapy was available, an Eastern Cooperative O
171 osis and offering these patients potentially curative therapy wherever appropriate is of utmost impor
172             Patients with PC not amenable to curative therapy who had received no prior therapy for m
173                        The safety of any new curative therapies will be paramount given the excellent

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