ライフサイエンスコーパス: curb

1 characterized by cracks, potholes, or broken curbs).

2 developed with the overfitting problem well curbed.

3 thholding a macrolide from patients with low CURB 65 scores, despite evidence that these patients hav

4 PSI had higher net benefit than mSOFA and CURB-65 for mortality, whereas mSOFA seemed more applica

5 l and the Pneumonia Severity Index (PSI) and CURB-65 scores were measured on admission.

6 a, Respiratory Rate, Blood Pressure and Age (CURB-65) score, and Pneumonia Severity Index (PSI) were

7 scrimination, followed by qSOFA, CRB, mSOFA, CURB-65, and PSI.

8 Taken together, the results reveal that RecG curbs a potentially negative effect of proteins that dir

9 , a Rho GTPase family member, is proposed to curb Abeta production.

10 2s is a major area of investigation aimed at curbing allergic lung inflammation and exacerbation.

11 P regulatory circuit in the hexose transport curb, although other redundant pathways also contribute.

12 onists and Y2R antagonists may be useful for curbing and/or preventing binge drinking, protecting vul

13 mobility (ie, walking down steps, stairs, or curbs), and driving.

14 grow unless additional measures are taken to curb anthropogenic P emissions.

15 Curbing antibiotic use requires the development of simpl

16 ors of endogenous ghrelin could be useful in curbing appetite and combating obesity.

17 PET/CT scanner after administration of (11)C-CURB ( approximately 350 MBq and approximately 2 mug).

18 , and methods by which this influence can be curbed are suggested.

19 tes of infection or tissue injury, likely to curb (auto)-inflammatory responses.

20 tion of APCs is a major regulatory mechanism curbing autoimmune responses and acts in concert with Fa

21 the importance of NOX-derived superoxide in curbing autoreactivity due, in part, to control of Treg

22 tion is key for efforts to develop agents to curb bacterial infections.

23 des the basis for taking effective action to curb biodiversity loss across the planet by 2020-an urge

24 effects of the cancer drug imatinib might be curbed by applying such premises.

25 hesize that the rate of BKV infection can be curbed by competitively preventing viral binding to cell

26 Tumor growth can also be curbed by pharmacologically uncoupling bioenergetic path

27 The early Paleozoic greenhouse may have been curbed by the evolution of rhizospheres with an increase

28 omprehensive gene profiling technologies are curbed by the problem of segregating these large amounts

29 V)2-mediated Ca(2+) rises are preferentially curbed by uptake into the endoplasmic reticulum and mito

30 dentify two small molecules that effectively curb cancer stem cell properties in a preclinical model.

31 rom deforestation and degradation (REDD) may curb carbon emissions, but the consequences for fire haz

32 ce, a focus on evidence-based practice and a curbed caring disposition.

33 uppressors, such as p53 and p19ARF (ARF), to curb cell cycle progression in response to increased c-M

34 esveratrol, restored apoptotic function, and curbed cell proliferation.

35 lexities of these factors will be pivotal in curbing CHIKV transmission.

36 reenhouse gases at the source are crucial to curb climate change, but due to insignificant economic i

37 ount the first phase of IFN-I production and curb CMV replication in infected mice.

38 is a viable target for therapeutics aimed at curbing colon carcinoma metastasis.

39 axation levels and/or additional measures to curb consumption).

40 e affordable, and realised new provisions to curb costs (including tests of new health-care delivery

41 umber of Americans unless steps are taken to curb current trends.

42 Whey protein has been indicated to curb diet-induced obesity, glucose intolerance and delay

43 reatment is to control infection and thereby curb disease progression.

44 F receptor polarity and function in order to curb disease progression.

45 Curbing domestic emissions of particulates and precursor

46 that while desensitization of nAChRs indeed curbs dopamine released by stimuli emulating tonic firin

47 y the successful development of ponatinib to curb drug resistance, we hypothesize that the incorporat

48 s to reduce HCV infection must be focused on curbing drug use and especially on the sharing of needle

49 egatively regulate the RUNX1 super-enhancer, curbing EBNA2 activation.

50 be a potential therapeutic target in SIRS by curbing effector cytokine production from CD8(+) T cells

51 ern transportation, which despite efforts to curb emissions, continues to play a critical role in env

52 Despite 20 years of effort to curb emissions, greenhouse gas (GHG) emissions grew fast

53 hat acylated ghrelin stimulates appetite and curbs energy expenditure during deficient energy intake,

54 of ethanol may help identify drug targets to curb excessive alcohol consumption.

55 tage for the host bacteria is that the SaPIs curb excessive phage growth while enhancing their gene t

56 Here, we show that TMEM16F is required to curb excessive T cell responses in chronic infection wit

57 ibition of PUMA expression may be useful for curbing excessive cell death associated with tissue inju

58 selective FoxO6 inhibition is beneficial for curbing excessive hepatic glucose production and improvi

59 In vivo studies revealed that Retro-2 curbed experimental L. amazonensis infections in a dose-

60 NA-directed Nedd4.2 gene silencing could not curb fatty acid-induced loss of SNAT2 adaptation.

61 This indicates that if governments act on curbing fire usage and effectively plan public health pr

62 ack loop is similar to the "hexose transport curb" first described almost 30 years ago.

63 To curb further extinctions and develop effective mitigatio

64 Consequently, immediate global action to curb future warming is essential to secure a future for

65 ene therapy provide an intriguing option for curbing glioma related deaths.

66 or, free fatty acid receptor 1 (Ffar1), that curbs glucose uptake when fatty acids are available.

67 Policies that attempt to curb greenhouse gas emissions, allocate emissions rights

68 The donor ACP (CurB) had high affinity for the enzyme (Kd = 0.5 muM) an

69 opagation and are potential drug targets for curbing herpesvirus infections.

70 coupling, might be of therapeutic value for curbing HF-exacerbating hyperaldosteronism.

71 Nrg4 gene transfer curbed HFD-induced hepatic steatosis by inhibiting lipog

72 ownregulated cell surface expression of MET, curbing HGF-independent MET activity, and engaged natura

73 for tyramine, and suggest that it serves to curb high levels of courtship activity through functioni

74 directed toward HIV-infected cells appear to curb HIV pathogenesis.

75 indicate that inhibiting inflammation could curb HIV propagation.

76 velopment of new microbicides or vaccines to curb HIV-1 infection at its earliest stages during mucos

77 ccines to prevent MTCT.IMPORTANCE Efforts to curb HIV-1 transmission in pediatric populations by anti

78 tegies to exploit miRNAs therapeutically for curbing HIV-1 infectivity, replication and latency since

79 worked to balance the ocean N budget and to curb ice age-interglacial change in the N inventory.

80 Blocking experiments demonstrated that regDC curb IFN-gamma secretion by NK cells through a dominant

81 country, or individual to fish sustainably, curb illegal fishing, or create large marine reserves as

82 these checks provide important guidance for curbing illegal sales.

83 th and duration of immune responses, thereby curbing immune-mediated tissue damage, regulating resolu

84 with positron emission tomography and [(11)C]CURB in 22 healthy control subjects and ten chronic cann

85 t absence of CaMK4 restores IL-2 production, curbs increased T cell activation, and augments the numb

86 These changes curbed infarct expansion and preserved left ventricular

87 in enhancing the ability of chondrocytes to curb inflammation in diseased joints.

88 Most of the known regulatory mechanisms that curb inflammatory gene expression target pre-transcripti

89 A2a agonists may be effective at curbing inflammatory lung tissue damage.

90 eroceptive cravings to cognitive control for curbing internal urges.

91 different families of viruses; while TRIM56 curbs intracellular YFV/DENV2 RNA replication, it acts a

92 atty acid amide hydrolase enzyme probe (11)C-CURB is within the same range as other radiotracers labe

93 (11)C-carbonyl-URB694 ((11)C-CURB) is a novel (11)C-labeled suicide irreversible radi

94 Valorization of industrial residues curbs issues related to food security and environmental

95 r the mutant protein efficiently and thereby curb its toxicity suffer the worst damage from polygluta

96 iates such as morphine more effective, while curbing its liability to be abused.

97 vels with anemia and make further efforts to curb lead pollution and childhood anemia.

98 Several BRAF inhibitors aimed at curbing MAPK pathway activity are currently in advanced

99 w therapeutic opportunities that may help to curb melanoma metastasis.

100 ption domain-associated protein (TRRAP), and curbed mTOR signaling, indicating that Tel2 affects all

101 ers and the importance of these findings for curbing N2O emissions.

102 ncluding cell-cycle arrest and apoptosis, to curb neoplastic growth.

103 all molecule inhibition of Wnt, were able to curb NF2 deficiency-elicited cell proliferation at the c

104 sufficiently high antibody concentration to curb nicotine distribution to the brain.

105 Continued public health efforts to curb obesity prevalence are needed to reduce the project

106 lization of the protein by the glass and the curbing of oxygen diffusion.

107 With curbs on emissions of these substances, the recovery of

108 l cholesterol in regions with decline and to curb or prevent the rise in Asian populations and elsewh

109 Interventions and policies that can curb or reverse the increase, and mitigate the health ef

110 reducing greenhouse gas emissions, and thus curbing, or even reversing, the increase in their atmosp

111 Most immediately, it can have a role in curbing outbreaks of hepatitis E in humanitarian crises.

112 Using this scaffold we ideate strategies to curb overgeneralization of fear in PTSD.

113 In the present study, we show that SOCS3 curbs pathologic angiogenesis.

114 ntly enacted federal legislation targeted at curbing perceived abuses of cash benefits for former Sup

115 This curbs phagocyte secretion of IL-23, a cytokine controlli

116 ocytes, attenuated infarct inflammation, and curbed post-MI left ventricular remodeling.

117 ncing of endothelial cell adhesion molecules curbed post-MI monocyte recruitment to the remote myocar

118 ntary approaches to improve the efficacy and curb potential toxicities of this approach.

119 ed pretreatment activity calculation methods curb potentially achievable tumor-absorbed dose values.

120 of Amazonian freshwater ecosystems cannot be curbed presently because existing policies are inconsist

121 ssociation with decreased number of appetite-curbing pro-opiomelanocortin (POMC) neurons; whether the

122 The transcriptional regulator STAT3 curbs pro-inflammatory cytokine production mediated by N

123 , synthetic challenges have, until recently, curbed progress.

124 estimate the radiation dosimetry from (11)C-CURB scans in humans.

125 red imatinib as an agent to treat GISTs with curbed side effects and reveal a bottom-up approach to c

126 finasteride as a novel therapeutic avenue to curb symptom fluctuations in TS.

127 the site of infection, which is essential to curb systemic virus spread.

128 draining the primary site of infection thus curbing systemic viral spread.

129 eiotropic cytokine that can both promote and curb Th2-dependent allergic responses.

130 tening antibiotics to improve cure rates and curb the alarming emergence of drug resistance is the ma

131 t young people, families, and communities to curb the commencement of smoking among children and adol

132 and TasP in real-world settings, efforts to curb the continuing HIV epidemic through use of these no

133 Pediatricians should help curb the epidemic through prevention and the usual pedia

134 ding active surveillance components, to help curb the epidemic.

135 nts already infected with HIV-1, may help to curb the epidemic.

136 ential to developing effective strategies to curb the global HIV epidemic.

137 ent as prevention" has emerged as a means to curb the global HIV epidemic.

138 e promising new field of immunometabolism to curb the global obesity and T2D epidemics.

139 To be able to curb the global pandemic of physical inactivity and the

140 massive investment in HIV treatment, and to curb the global TB burden.

141 injection-risk behaviors simultaneously may curb the growing HIV epidemic in the Mexico-US border re

142 eproducibility of (bio)chemical research and curb the growing trend of structural misassignments.

143 iciency virus (HIV)-1 are urgently needed to curb the growth of the acquired immunodeficiency syndrom

144 the general population and whether they can curb the growth of the infected group while keeping the

145 Treatment interventions to curb the HCV epidemic among HIV-infected men who have se

146 te new guidelines that will serve efforts to curb the hepatitis C epidemic, rather than frustrate the

147 ivity in reviewer decisions, which serves to curb the herding process, can be beneficial for the scie

148 -term health-care and prevention services to curb the HIV epidemic and improve the quality of life of

149 immunodeficiency virus (HIV) transmission to curb the HIV epidemic, there is a need to develop evalua

150 therapeutic vaccine offers the best hope to curb the HIV-AIDS epidemic gripping sub-Saharan Africa,

151 AIDS (UNAIDS) has set a "90-90-90" target to curb the human immunodeficiency virus (HIV) epidemic by

152 bilitation programs after transplantation to curb the muscular loss and (ii) systematic attention to

153 rgence of resistance and support the need to curb the nontherapeutic use of medically important antim

154 pneumoniae colonization has the potential to curb the number of HAIs.

155 division but turn on asymmetric division to curb the number of ISCs when proinflammatory response ca

156 exclusivity of breastfeeding are unlikely to curb the obesity epidemic.

157 ioidergic function might thus be critical to curb the obesity epidemic.

158 products may limit their appeal to youth and curb the onset of cigarette smoking.

159 epidermal progenitor cells where it acts to curb the rate of proliferation as well as in their proge

160 inflammatory cytokines and chemokines and to curb the recruitment of inflammatory myeloid cells into

161 Effective strategies are needed to curb the reemerging epidemic of HDV infection in these h

162 al food ingredients are critically needed to curb the rise in metabolic disease.

163 n to Combat Antibiotic-Resistant Bacteria to curb the rise of "superbugs," bacteria resistant to anti

164 Visionary political leadership is needed to curb the rise of MDR and XDR tuberculosis worldwide, thr

165 in the most affected countries in Africa to curb the rising burden of disease and control future out

166 tion and other preventive therapies may help curb the rising incidence of HF.

167 ers local communities a legal avenue to help curb the rising tide of juvenile smoking without raising

168 as potential supplements for microbicides to curb the spread of HIV-1 through sexual contact.

169 s that warrant further investigation to help curb the spread of these potentially lethal organisms.

170 emented a number of innovative strategies to curb the transmission of wild poliovirus (WPV) in the co

171 In an effort to curb the treatment costs of this common disorder, ration

172 To curb the trend toward increasingly resistant microorgani

173 siness has hindered public health efforts to curb the use of tobacco products.

174 ivin A in skeletal muscle, whereas activin A curbed the IL6-induced acute-phase response in liver.

175 adrenocorticotropic hormone and cortisol and curbed the meal-related rise in plasma glucose.

176 Inclusion of unsaturated R groups curbed the overall reactivity (varphi = 1 to 2 orders of

177 rohibit commercial transplants in India have curbed the trade.

178 but possible complications have temporarily curbed the use of this vaccine.

179 nal innovation and purifying selection, thus curbing the concentration imbalance arising from gene du

180 t antiviral strategies would be effective in curbing the dangers of a re-emergent 1918 or 1918-like v

181 ulted in a more potent and reliable means of curbing the effects of activated PKR.

182 rent multi-faceted preventive strategies for curbing the epidemic of diabetes in the older population

183 Curbing the epidemic will require maximizing the impact

184 mic, rendering these measures ineffective at curbing the epidemic.

185 he role of treatment as prevention (TasP) in curbing the epidemic.

186 he transcription of lytic IE1/IE2 mRNA while curbing the expression of latency-associated UL138 mRNA.

187 proteasome inhibitors have the potential of curbing the growth of a c-myc-related tumor.

188 By curbing the information-degrading effects of cell-to-cel

189 t VGF is required for the effects of LiCl in curbing the response to amphetamine.

190 rol and public health interventions aimed at curbing the spread of antibiotic-resistant pathogens.

191 While public health policies aimed at curbing the underlying causes of the obesity epidemic ar

192 nce, a focus on evidence-based practice that curbs the ad hoc repertoire of the caring disposition.

193 ay represent an evolutionary adaptation that curbs the amplified infection risk after CNS trauma, due

194 L-27R-/- mice, these data suggest that IL-27 curbs the development of immunopathology by limiting par

195 c RTL therapy induces a cytokine switch that curbs the encephalitogenic potential of PLP 139-151-spec

196 y a Toll-like receptor agonist that not only curbs the host inflammatory response but also eliminates

197 ed either epithelial cadherin (E-Cad), which curbs the malignant behavior of tumor cells, or neuronal

198 To investigate whether ATXN1[30Q]-D776 curbs the progressive disease in ATXN1[82Q]-S776 mice, w

199 , allotransplanted and autochthonous tumours curb their growth, thus extending animal survival by 37%

200 ered for making opiates more effective while curbing their liability to be abused.

201 ceae to pinpoint possible control points for curbing their spread.

202 n intervention known as self-affirmation can curb these negative outcomes.

203 on gill poxvirus in Atlantic salmon may help curb this disease and provide comparative knowledge.

204 g studies and begun to develop approaches to curb this growth.

205 al activation of an inhibitory pathway might curb this initial steep rise in firing rate.

206 infection control practices is essential to curb this nosocomial, iatrogenic disease.

207 eling and management, critically required to curb this rare disorder in the families.

208 ical interactions in silicate-rich rocks may curb this transport drastically and even inhibit it alto

209 cation about the low risk of CBC may help to curb this trend.

210 a vaccine is the best long-term solution for curbing this global epidemic.

211 principle that epigenetic interventions can curb TNR expansions.

212 ontinuous supply of potent killer T cells to curb Toxoplasma gondii growth during latency.

213 with a positive test result could profoundly curb transmission.

214 s crucial for the design of interventions to curb transmission.

215 osis, but the ability of diagnostic tests to curb tuberculosis transmission is dependent on multiple

216 re appealing candidates to reprogram TAM and curb tumor-mediated immunosuppression, thereby empowerin

217 e efficacy of RFA in producing local cure or curbing tumor progression during the waiting period.

218 Inactivation of PIN1 function conversely curbs tumour growth and cancer stem cell expansion, rest

219 rtant to understand what mechanisms exist to curb unwanted activation.

220 lerance in vivo, and as a potential means of curbing unwanted T cell responses.

221 ong e-cigarette regulation could potentially curb use among youth and possibly limit the future popul

222 These data show that Abr and Bcr normally curb very specific functions of mature tissue innate imm

223 This process could be curbed via enforced expression of retrovirally encoded P

224 pression of a subset of antiviral genes that curb viral replication until mitochondrial MAVS can indu

225 alpha/beta interferon receptor is needed to curb viral replication, it is dispensable for the induct

226 , thereby slowing down the host's ability to curb virus replication and induce adaptive immunity.

227 imultaneously suppress virus replication and curb virus-induced detrimental host immune responses in

228 In some cases, cell death curbs virus replication.

229 (11)C-CURB was well tolerated in all subjects, with no radiotr

230 sight into creating optimal interventions to curb weight gain in women with breast cancer.

231 The LOS inhibitory effect was curbed when all 3 factors were expressed, which suggests

232 uced BFR (-92%), a suppression only slightly curbed when disuse was interrupted by 10 min of weight b

233 Health and social policies are needed to curb widening life expectancy inequalities, help deprive