ライフサイエンスコーパス: curing

1 arise again in the cured strain (reversible curing).

2 r1p, with both proteins needed for efficient curing.

3 eactions throughout the whole process of dry-curing.

4 [URE3], and Hsp42p aids Btn2 overproduction curing.

5 reby providing a powerful system for protein curing.

6 30 KHz) during and up to 10 min after light curing.

7 ccurring in the different muscles during dry-curing.

8 evented Sup35 fragmentation and caused prion curing.

9 f crosslinking, gel time, degree and rate of curing.

10 p is a specific Hsp40 important for [PSI(+)] curing.

11 saggregation does not adequately explain the curing.

12 portant for the contribution of ubiquitin to curing.

13 g approximately 1.4 microm thick films after curing.

14 ubstrate to Hsp70 had little or no effect on curing.

15 posites became more opaque or translucent on curing.

16 a carboxylic acid to the prepolymer prior to curing.

17 temperature-sensitive replicons to simplify curing.

18 ne to nornicotine during leaf senescence and curing.

19 and the weaker the variant, the greater the curing.

20 thermosets maintain their malleability after curing.

21 imately 1.5 h, not including overnight epoxy curing.

22 performed 0, 1, 3, 5, and 10 min after light curing.

23 in the acute mouse model of trypanosomiasis, curing 3/4 or 4/4 animals at 4 x 5 mg/kg.

24 highly significant improvement in survival, curing 33% to 90% of the animals, even at relatively low

25 the bispecific outperformed the SA approach, curing 35% more mice overall (P < .004).

26 2 in MM and NHL xenograft models, ultimately curing 80% of mice at optimal doses.

27 The first step in curing a disease is being able to detect the disease eff

28 ll, tissue, or whole organ, with the goal of curing a disease or at least improving the clinical stat

29 bination immunotherapies that are capable of curing a majority of tumors in experimental settings typ

30 of a particular intervention in managing or curing a specific condition, there exists a substantial

31 ack PDMS microfluidic devices, fabricated by curing a suspension of charcoal in PDMS, were used to me

32 -nitrosyl-myoglobin and is the basis of meat curing, a greater biological activity of the nitrite ani

33 l dimethacrylate, which showed a unique self-curing ability.

34 tion, thus separating filament cleavage from curing activities.

35 The curing activity of Hsp104 thus constitutes an antiprion

36 erivatives for understanding, diagnosing and curing AD.

37 n to achieve PVAI is a promising approach to curing AF.

38 MS)-based polymers synthesized with peroxide curing agents having tert-butyl side groups.

39 that MTBE is one of the byproducts of these curing agents, which cross-link PDMS via the methyl side

40 e seen in septa whose formulations use these curing agents.

41 ection, has been proposed as one approach to curing AIDS.

42 rve as a novel and effective platform toward curing AIDS.

43 excellent antitrypanosomal efficacy in vivo curing all infected animals in the STIB900 acute mouse m

44 antitrypanosomal efficacy than melarsoprol, curing all infected mice.

45 lantation (SCT) has been proven effective in curing AML by allowing for the administration of otherwi

46 Mermessus fradeorum and then used antibiotic curing and controlled mating assays to demonstrate that

47 time of the 3D model, and including time for curing and drying of materials, this procedure can be co

48 chemistry is employed to achieve rapid light-curing and minimize residual monomer of the lead materia

49 carcinogen N'-nitrosonornicotine during the curing and processing of tobacco.

50 e dependent on both postsilanization thermal curing and silanization time and relatively independent

51 Curing and storage for up to 8 months did not significan

52 ere collected at different stages during dry-curing and submitted to magnetic resonance imaging (MRI)

53 p in attempting to devise ways of arresting, curing, and preventing neuromuscular diseases.

54 l interactions of Ydj1p with Hsp70 abolished curing, and the J domain alone cured [URE3].

55 dication of both primary and distant tumors, curing animals of disease.

56 In this study, after successfully curing APEC of its plasmids, we were able to investigate

57 Rather, curing apparently occurs because Sup35-GFP polymers slow

58 l production, antimicrobial therapy, and for curing arthropods infected with bacterial endosymbionts

59 microbial activity in the in vivo C. elegans curing assay.

60 We also find curing associated with cell division.

61 r precursors with block copolymer templates, curing at 140-180 degrees C, and calcination to remove t

62 l congeners were more active than 1 in vivo, curing at least 2/4 infected animals in the acute mouse

63 diethylnyl oligomer precursor and then heat curing at temperatures between 300 and 1000 degrees C to

64 XPL can be topically applied, rapidly curing at the skin interface without the need for heat-

65 We propose a new paradigm focused on curing atherosclerosis early in the course of the diseas

66 However, curing B-ALL and CML mice requires killing leukemic stem

67 ith severe restrictions on biocompatibility, curing behavior, esthetics, and ultimate material proper

68 only 0.4-0.5% of Hg escaped from mixing and curing BFD-added cement.

69 ed with preventing, treating, and ultimately curing breast cancer are addressable in the laboratory,

70 hat elevating free ubiquitin levels enhances curing, but it did not overcome inhibition of curing cau

71 ability of excess Ssa to counteract [PSI(+)] curing by excess Hsp104.

72 ces de novo [PSI(+)] appearance and prevents curing by excess Hsp104.

73 +)] prion oligomers increase during [PSI(+)] curing by excess Ssa1.

74 Therefore, curing by Hsp104 overexpression depends on both the trim

75 uction, cures [PSI+], and potentiates [PSI+]-curing by Hsp104 overexpression.

76 oles of Hsp70, Sti1, and Hsp90 for efficient curing by overexpressed Hsp104 and provide evidence supp

77 n of BTN2 and CUR1 stabilizes [URE3] against curing by several agents, produces a remarkable increase

78 Btn2p nor Cur1p is needed for overproduction curing by the other.

79 , were exclusively identified at 9 months of curing by using both methodologies so that these peptide

80 In livers of susceptible but self-curing C57BL/6 mice, intracellular Leishmania donovani i

81 nd create public health benefits on par with curing cancer.

82 uring, but it did not overcome inhibition of curing caused by Hsp90 defects, suggesting that Hsp90 ma

83 40 chaperone, Sis1, rescues this toxicity by curing cells of [PrD(157)(+)].

84 Curing cells of [PSI(+)] alters their survival in differ

85 Curing CHC was associated with a reduction in MR among c

86 lthough important advances have been made in curing childhood cancer in the last several decades, lon

87 ased regeneration therapy for controlling or curing chronic human diseases is highly attractive.

88 ly, we find both drugs are more effective at curing chronic infections, judged by treatment duration

89 axomicin to be noninferior to vancomycin for curing Clostridium difficile infection (CDI) and superio

90 The success of FMT in curing Clostridium difficile infection (CDI) is well est

91 Curing CML depends on the eradication of LSCs.

92 herapeutic strategies aimed at preventing or curing CNS infection.

93 Here we explore the possibility of curing colour blindness using gene therapy in experiment

94 oncentration of PMMA, spin coating speed and curing condition, we obtained very smooth and ultrathin

95 For monitoring of curing conditions of each coating in the array, a viscos

96 ns about the influence of the components and curing conditions on the mechanical properties of the su

97 sition of the spotting buffer, postspotting "curing" conditions, and postspotting wash conditions.

98 se heating procedure, independent of nitrite-curing, depending strongly on the fecal inoculum used.

99 refractive index mismatch provides increased curing depth and assists shade-matching.

100 he current short wavelength initiators limit curing depth and efficacy because they do not absorb wit

101 ent, and combination chemotherapy capable of curing diffuse aggressive lymphomas.

102 utaneous leishmaniasis is an ultimately self-curing disease for which systemic therapy with pentavale

103 uired disorders have made the possibility of curing diseases a reality.

104 The majority ranked developing medicines and curing diseases as the most important contributions of s

105 eventive or therapeutic approaches aiming at curing DNP.

106 Gene therapy holds great promise for curing Duchenne muscular dystrophy (DMD), the most commo

107 r the Bayonne ham is directly related to its curing due to the salt used in process coming from the n

108 nd Stem cell factor and offers the chance of curing early-stage disease while preventing neuroendocri

109 ive review, CMT with LDIFRT was effective in curing early-stage HD and was not associated with an inc

110 alterations indeed act on polyglutamines via curing endogenous prions, other alterations decrease siz

111 Methods for curing endogenous prophages from the comK attachment sit

112 Here, we conduct curing experiments, intra- and interspecific crosses, cy

113 ial role in MTBE degradation through plasmid-curing experiments.

114 continued to propagate after composite light curing finished.

115 Light cure is a popular mode of curing for dental adhesives.

116 enchymal stem cells') hold the potential for curing generalized skeletal diseases, their clinical eff

117 and thus could be a means of ameliorating or curing genetic diseases in which a deficiency of liver c

118 el TSHR Ag-specific immunotherapies aimed at curing Graves' disease in humans.

119 Nitrite-curing had an antioxidant effect during digestion, but t

120 exuded adhesive substances, favor subsequent curing (hardening) via formation of an adhesive film, an

121 Indeed, curing HCV infection with an oral medication is now real

122 may represent a viable treatment option for curing HCV infection.

123 es has been paramount to the VA's success in curing HCV infection.

124 ietic stem cell transplantation (alloSCT) in curing hematologic malignancies is due to a graft-versus

125 Interventions aimed at curing HIV infection have the potential to improve overa

126 Recent case reports have suggested that curing HIV infection is possible, renewing excitement ab

127 viral persistence and hence be a barrier to curing HIV infection.

128 is critical because it is a major barrier to curing HIV infection.

129 therapy (cART) presents a major barrier for curing HIV infections.

130 nfected CD4+ T cells is the major barrier to curing HIV, and has been extensively studied in this lig

131 re critical to understanding the barriers to curing HIV-1 infection.

132 Elimination of this reservoir is critical to curing HIV-1 infection.

133 ells (rCD4 cells), posing a major barrier to curing HIV-1 infection.

134 common with ART and is the major barrier to curing HIV-1 infection.

135 emory CD4(+) T cells is the major barrier to curing HIV-1 infection.

136 tic implications with respect to the goal of curing HIV-1 infection.

137 CD4(+) T cells serves as a major barrier to curing HIV-1 infection.

138 combination antiretroviral therapy and make curing HIV-1 infections a major challenge.

139 The barrier to curing HIV-1 is thought to reside primarily in CD4(+) T

140 rapies (ART) and remain the major barrier to curing HIV-1.

141 ish a latent infection presents a barrier to curing HIV.

142 IV-1 provirus represents a major obstacle to curing HIV.

143 (TPR) interaction motif was dispensable for curing; however, cells expressing Sti1 defective in Hsp7

144 fly, Drosophila melanogaster, contribute to curing human diseases of the nervous system?

145 and the Hsp90 inhibitor radicicol abolished curing, implying that Sti1 acts in curing through Hsp70

146 of Hsp104p on both prion induction and prion curing in a prion-specific manner.

147 This latent reservoir is a major barrier to curing individuals of HIV-1 infection.

148 that enable their identification: reversible curing, inducible "spontaneous generation," and phenotyp

149 ovirus and rotavirus, in both preventing and curing infection.

150 ch they contribute to reservoirs relevant to curing infection.

151 Curing infections increasingly requires antimicrobials t

152 age stress attained with soft-start or pulse curing is a modest decrease in final conversion.

153 Hsp104 deficiency curing is a result of failure to cleave the Sup35p amylo

154 This curing is enhanced in the presence of [PIN(+)].

155 This normal-level Hsp104 curing is promoted by Sti1p, Hsp90, and Sis1p, proteins

156 on of these prions, but its role in [PSI(+)] curing is unknown.

157 Btn2p, in curing, is colocalized with Ure2p in a single locus, sug

158 tention and symbolizes current confidence in curing it.

159 photochemically with the screws in place; on curing, it bonds to the surrounding layer of PDMS and fo

160 We hypothesize that curing light transmission and cure depth are influenced

161 include the following information about the curing light: 1) radiant power output throughout the exp

162 oxyphenyltrioxanes are highly efficacious in curing malaria-infected mice.

163 in 17XNL (Py17XNL), induce a transient (self-curing) malaria infection.

164 otein 9) system, hold clinical potential for curing many monogenic disorders, including neuromuscular

165 insights into new therapeutic strategies for curing memory loss in the disease.

166 g cause of cancer death in American men, and curing metastatic disease remains a significant challeng

167 o display to ensure high resolution of photo-curing methacrylate based SMPs that requires higher expo

168 es to an MV protein were highly effective at curing mice from ECTV infection when administered after

169 fficacious in an in vivo model of infection, curing mice infected with a lethal dose of S. aureus.

170 as superior to either drug alone, capable of curing mice.

171 Despite curing millions, these drug regimens are limited by the

172 erapy of choice for most patients with JMML, curing more than 50% of affected children.

173 bitors markedly improved treatment outcomes, curing more than 80% of the tumor-bearing mice.

174 g high-throughput screens, we identify prion-curing mutants and engineer "anti-prion drives" that rev

175 The high bonding strength, the fast-curing nature, and the composition of the biobased mater

176 neurodegeneration provides the best hope of curing non-motor symptoms.

177 and dynamic temperature scan DSC with light-curing occurring immediately, or at 5 or 10 minutes afte

178 ake new seeds, whereas Hsp104 overproduction curing occurs by a different mechanism.

179 phenotype that was also observed during the curing of [PSI(+)] by certain variants of [PIN(+)].

180 Curing of [PSI(+)] by overexpressing catalytically inact

181 -21 impairment of [PSI(+)] and blocks Hsp104 curing of [PSI(+)].

182 usly implicated in the Hsp104 overproduction curing of [PSI(+)].

183 this reduction in aggregation suggested that curing of [PSI+] by inactivation of Hsp104 might be inde

184 This was tested by measuring the rate of curing of [PSI+] cells in both dividing and nondividing

185 We demonstrate that both curing of [URE3] and enhancement of [PSI(+) ] in the pre

186 Our data imply that curing of [URE3] by overproduced Ydj1p does not involve

187 Cur1p is needed for Hsp42 overproduction curing of [URE3], but neither Btn2p nor Cur1p is needed

188 ation of temperature conditions of radiation curing of arrays of organic protective coatings for auto

189 derable shrinkage stress develops during the curing of dental composites, various soft-start photocur

190 ected population (created through antibiotic curing of infected females) were mated to uninfected fem

191 ntilevers are fabricated by ultraviolet (UV) curing of PEG-DA prepolymer introduced into a poly(dimet

192 Curing of pFKN (creating Psm M6C) caused a significant r

193 on-productive self-adherence, and preventing curing of the adhesive.

194 Thorough curing of the devices is obtained through the combined u

195 elative to parental controls, and antibiotic curing of the gut bacteria significantly rescues hybrid

196 We experimentally characterize how the curing of the polymer affects its drainage dynamics and

197 e application of a magnetic field during the curing of the prepolymer resin.

198 Curing of the prion form of Rnq1 from wild-type cells dr

199 Conversely, curing of the replicon from these cells results in dimin

200 Oxidation of dopa, as occurs during curing of the secreted mussel glue, dramatically reduces

201 can be permanently retained by templated UV-curing of the solvent, offering great promise for comple

202 (D184N) that confers resistance to guanidine-curing of the yeast [PSI(+)] prion.

203 ies will enable the permanent prevention and curing of type 1 diabetes.

204 ling of temperature and radiation effects in curing of UV-curable coating formulations by using multi

205 the enigmatic specificity of Hsp104-mediated curing of yeast prions and sheds light on the limitation

206 PG2-expressing MDA MB 361 xenografts, either curing or greatly inhibiting tumor growth and extending

207 d varying degrees of resistance to guanidine-curing or impaired [PSI(+)] propagation.

208 t step toward preventing this cell death and curing or slowing the disease.

209 ptimization of processing conditions such as curing parameters in fabrication of UV-cured automotive

210 have long been known to be more effective in curing patients than single drugs, the impact of such tr

211 The only current treatment capable of curing patients with myelodysplastic syndromes (MDS) is

212 Although there are no current means of curing PD, the understanding of reactive oxygen species

213 fic T cells in causing lethal CNS disease or curing pervasive and life-long CNS infection.

214 Hsp104 then counteracts this curing possibly by catalyzing formation of new polymers.

215 Curing PrD-GFP prions, by inhibiting Hsp104's fragmentat

216 idised peptides generated throughout the dry-curing process (0, 2, 3.5, 5, 6.5 and 9months), focusing

217 f the giant protein titin throughout the dry-curing process (2, 3.5, 5, 6.5, and 9 months) through th

218 sarcoplasmic proteins throughout the ham dry-curing process by using a label-free mass spectrometry m

219 UV curable resin followed by an immediate UV curing process to polymerize the droplets and fix the or

220 of naturally generated peptides during a dry-curing process, showing methionine (Met) oxidation in th

221 During the curing process, those cells having both Ure2p-GFP aggreg

222 peptides naturally generated during the dry-curing process.

223 of the oxidation mechanisms occurring in dry-curing processing.

224 sis enzyme, a phage integrase and a death-on-curing protein.

225 Also dry-curing proved a promising technique for masking boar tai

226 ell division is not a determining factor for curing [PSI+] by inactivating Hsp104 with guanidine.

227 In a screen for antiprion systems curing [PSI+] without protein overproduction, we detecte

228 isible lesion," we may be one step closer to curing psoriasis.

229 able formulations can be analyzed during the curing reaction.

230 Btn2p curing requires cell division, and our results suggest t

231 el approaches to predicting, preventing, and curing respiratory disease.

232 , and the utilization of soft-start or pulse curing results in specimens with reduced final conversio

233 The effects of a curing salt composition (with and without nitrifying sal

234 n nicotinamide and decrease in pyridoxine by curing salts and the decrease in both vitamins by pH24,

235 nces (TBARS) were reduced by the addition of curing salts but were low in all cases, suggesting high

236 In most cases, reduction of curing salts content resulted in significant increase of

237 The effect of the concentration of curing salts, the nature of the probiotic culture (free

238 as tools for understanding skin biology and curing skin disease outweigh potential toxicity concerns

239 in this issue demonstrate the feasibility of curing spontaneous autoimmunity in animal models via sho

240 nking was accomplished by a simple, brief UV curing step at modest temperatures.

241 ich requires no further modification/ex-situ curing step.

242 rethane dimethacrylate denture resins in the curing step.

243 ovington, and NC07-847) at harvest and after curing/storage for 4 or 8 months.

244 y almost always improves, if not permanently curing, strabismic deviations.

245 is crucial for designing the prevention and curing strategy of cancer.

246 During curing, Sup35-GFP fluorescent aggregates get bigger and

247 mbine a gradient temperature heater and a UV curing system with the full capabilities of our high-thr

248 o advances in understanding, preventing, and curing T1D has been the inability to "see" the disease i

249 ew approaches to preventing, diagnosing, and curing TB are needed, which depend on a better understan

250 l could exist for US to enhance conventional curing techniques.

251 By varying curing temperature and resin formulation, the clear tren

252 ckness combinations, coating properties, and curing temperature for operation in liquid environments.

253 The incorporation of Al and increased curing temperature promotes the crystallization and cros

254 h poly(4-vinyl)phenol (PVP) require very low-curing temperatures ( approximately 110 degrees C) and a

255 S. cerevisiae prion domain are necessary for curing the [URE3] prion.

256 Curing the adhesive furnished mechanically stable aggreg

257 Curing the adhesive with ultraviolet light furnishes mec

258 o satisfying interventions for preventing or curing the disease emphasize the need to better understa

259 ed individuals and hence a major obstacle in curing the disease.

260 HIV-1 reservoirs as they create barriers to curing the disease.

261 s of persistent virus infection, effectively curing the host of infection.

262 lead to novel interventions aimed at either curing the infection or preventing the development of in

263 pe 1 (HIV-1) remains a principal obstacle to curing the infection.

264 on-to-treat basis, opens the perspective for curing the large majority of these so far difficult-to-t

265 Although curing the leukemia is always the most formidable challe

266 ith a combination of F8-TNF and doxorubicin, curing the majority of treated animals (29/37).

267 sity achieved in the focal region allows for curing the material quickly, while the brief duration of

268 After curing the printed PDMS, the paper-based devices can be

269 physical aggregation pattern of Rnq1 without curing the prion.

270 r Treg alone or Treg-depleted CD4 T cells in curing the scurfy mice.

271 In vivo assays showed that curing the three plasmids resulted in severe attenuation

272 Curing the trxR mutation restored virulence comparable t

273 leos(t)ide analogues are capable of reliably curing the viral infection.

274 After curing, the chips were carefully removed from the mold a

275 ivity of Hsp104, leading to so called "prion curing," the loss of prion-related phenotypes.

276 ycobacterium tuberculosis (Mtb) infection by curing them of a primary lung infection were compared wi

277 adhesive system is detrimental to the light-curing thereof.

278 icate the utility of chromatin remodeling in curing this complex autoimmune disorder.

279 ing new therapeutic targets and, ultimately, curing this disease.

280 There are currently no options for curing this infection.

281 abolished curing, implying that Sti1 acts in curing through Hsp70 and Hsp90 interactions.

282 ences (p > .05) in DC within each increasing curing time between the modified adhesives compared to S

283 dium, with stiffnesses controlled by polymer curing time; (2) heart cell contractility inducible by e

284 Increasing curing times (10, 20, 40 sec) led to increased DC values

285 sors is more challenging due to their longer curing times.

286 ay include cryogenic fuel-filling, and shell curing, to produce ready-to-use IFE targets.

287 rstand the relationship between trimming and curing, trimming was followed by measuring the loss of G

288 s in the long-term goal of preventing and/or curing type 1 and type 2 diabetes.

289 Curing type 1 diabetes by islet transplantation requires

290 scal investments, no means for preventing or curing type 1 diabetes exists, and, globally, the qualit

291 slet transplantation has great potential for curing type 1 diabetes; however, long-term islet surviva

292 get that can be harnessed for preventing and curing type 2 diabetes.

293 Thermal curing under reduced pressure or chemical cross-linking

294 The output from a light-curing unit (LCU) is commonly characterized by its irrad

295 nergistically increased mouse survival time, curing up to 10%.

296 led to the concept of lethal mutagenesis for curing viral infections, and work with drugs such as rib

297 the therapeutic potential of IFN-lambda for curing virus infections in the gastrointestinal tract.

298 of these methods, we found that the rate of curing was not significantly affected by cell division.

299 with a more transparent phenotype and phage curing with more opaque colonies in all strain pairs, an

300 sp104 homolog in vitro, and is essential for curing yeast prions by Hsp104 overexpression in vivo.