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1 rative capacity of these T cells is severely curtailed.
2 se of the perception that benefits are being curtailed.
3 ompound, temperature-induced F activation is curtailed.
4 CHO mutants unable to produce HSPGs was also curtailed.
5 ction, whereas editing of others is severely curtailed.
6 ch the inhibitory activities of IFNgamma are curtailed.
7 sion, this interstitial diffusion process is curtailed.
8 sis, but the productive program was severely curtailed.
9 protein, the growth of the cells is severely curtailed.
10 as recombination at niche-specific genes is curtailed.
11 t atherogenesis, the formation of plaque, is curtailed.
13 epressing the expression of VEGFR-1, thereby curtailing a central angiogenic driver of vascular growt
14 extinction, measuring the rate and extent of curtailing a response that was previously, but is no lon
15 to incoming 'foreign' DNA, their activity is curtailed; a process known as restriction alleviation (R
16 iency in mice reduces microglial activation, curtails abnormal vessel growth, and allows for rapid no
17 ormulations can have the intended purpose of curtailing abuse, but the extent of their effectiveness
19 mmalian target of rapamycin kinase primarily curtailing activity of the target of rapamycin complex (
22 , viral growth in cultured D2F2/E2 cells was curtailed after several cycles, and viral yield was very
23 lished CD8+ T cells were able to effectively curtail Ag presentation, resulting in limited CD8+ T cel
24 r pharmacologic inhibition of Pim-1 activity curtails AKT inhibitor-induced upregulation of RTKs in p
25 atment modalities are needed to eliminate or curtail alloantibody production and its deleterious effe
27 tted that a pro-inflammatory environment may curtail anti-tumor immunity and favor cancer initiation
29 al evaluation of a sequence of choices, they curtailed any further evaluation of a sequence as soon a
31 rsely, glycolysis and lipid biosynthesis are curtailed as sugar levels decrease and KIN10 regains act
32 nlikely to evolve resistance be developed to curtail associated morbidity and mortality and ultimatel
38 ested populations to recover once harvest is curtailed because harvesting often creates strong select
39 h LLINs, their transmission potential may be curtailed because of longer-term fitness costs that pers
40 diseases consultation and management will be curtailed because we provide cognitive services that are
42 the 3,5,3',5'-positions of the ABP units to curtail binding by the CBPQT(4+) ring if not sterically
43 biting integrins alpha1beta1 and alpha5beta1 curtails both galectin-8- and VEGF-C-mediated LEC sprout
45 ation of this approach, however, is severely curtailed by allograft rejection primarily initiated by
46 whose microtubule and kinetochore binding is curtailed by Aurora B is the spindle and kinetochore-ass
47 n the newborn mammalian heart, it is quickly curtailed by developmental mechanisms that render cardio
48 ty in various cancer types, but their use is curtailed by dose-limiting side effects such as hypergly
51 tidepressant in routine clinical settings is curtailed by its abuse potential as well as possible psy
56 self-administration training, responding was curtailed by requiring rats to cross an electrified floo
57 the therapeutic promise of QS-21 adjuvant is curtailed by several factors, including its scarcity, di
59 sion of Ag-specific CD4 T cells was slightly curtailed by the absence of IL-18Ralpha; however, contra
61 pproximately 60 min, which is only prevented/curtailed by the arrival of the opposing replication for
62 ch a C-H activation reaction can be severely curtailed by the distance of the C-H bond in question fr
63 tive antipsychotic medication but its use is curtailed by the risk of clozapine-induced agranulocytos
65 apy could serve as a microbiota surrogate to curtail C. difficile colonization of antibiotic-treated
69 Simultaneous loss of both pathways severely curtails CE resulting in a shortened, anteriorly displac
70 eripheral linkers in any manner dramatically curtailed channel opening, highlighting the requirement
71 These results suggest new approaches both to curtail CMV infection and to purge the virus from organ
73 ne dynamics offering a promising strategy to curtail deleterious socioaffective effects of stress and
74 ymatically active but clustering defective), curtailed dendritic growth, spine formation, and long-te
76 ion and that overexpressing CEACAM1 in liver curtailed diet-induced metabolic abnormalities by protec
77 (RAD27) during strand displacement synthesis curtails displacement in favor of flap cutting, thus sug
78 l key events in which ICP27 plays a role are curtailed during infection with ICP27 phosphorylation si
80 neous lymphocyte subpopulation essential for curtailing effector T cells and establishing peripheral
81 hat EndoMT contributes to renal fibrosis and curtailing endothelial TGF-beta signals favors Smad1/5 p
83 pancreas-specific deletion of Stat3 in mice curtailed ER-mediated suppression of lipid synthesis.
86 nels (SK channels) modulate excitability and curtail excitatory postsynaptic potentials (EPSPs) in ne
89 tegy by both suppressed neovessel growth and curtailing fibrosis typically associated with the involu
90 esults in a loss of the ability of leptin to curtail food intake and suppress expression of Agrp.
93 enforcement in these two hotspots could help curtail future elephant losses across Africa and disrupt
94 e calls in the media to destroy the viruses, curtail future research in this area, and protect the pu
101 eptual challenge of designing therapies that curtail glucose production without promoting hepatic lip
102 by the AMP-activated protein kinase Snf1 to curtail glycerol production when nutrients are limiting.
103 se by citrate, which accumulated and thereby curtailed glycolytic outflow in nitrogen-limited yeast.
104 inase also attenuated synapse maturation and curtailed growth and varicosity formation of sensory neu
105 e (MAPK), attenuated synapse maturation, and curtailed growth of sensory neurons contacting L7, but n
106 eatitis by degrading trypsinogen and thereby curtailing harmful intra-pancreatic trypsinogen activati
107 ates strong selection differentials, whereas curtailing harvest will often result in less intense sel
108 e from the perspectives of improving health, curtailing health care expenditures, and job creation an
110 eostasis and limit autoimmunity but can also curtail host immune responses to various types of tumors
112 Immunized Zbtb20-deficient mice exhibit curtailed humoral responses and accelerated loss of anti
113 (cKOs; ell2(loxp/loxp) CD19(cre/+)) exhibit curtailed humoral responses both in 4-hydroxy-3-nitrophe
114 ells' primary response to anti-CD3 antibody, curtailing IL-2 production, and preventing entry into th
115 lator of the Roquin ubiquitin ligase, Roquin curtails IL-17A synthesis, and the 3' untranslated regio
119 ation of how variable gene expression can be curtailed in developing cells to ensure their differenti
120 starvation, whereby stable RNA synthesis is curtailed in favour of transcription of amino acid biosy
121 ulation of glutamate during PIDs is strongly curtailed in Ip3r2-deficient mice, resulting in ameliora
123 ess number of TUNEL(+) apoptotic neurons and curtailed induction of caspase-3 and Bax, compared to ve
124 ia/macrophages and ICAM1(+) capillaries, and curtailed induction of pro-inflammatory genes IL6, MCP1
129 to this clinically relevant strain of Mp by curtailing inflammatory cell recruitment and limiting an
130 ble and can potentially be used initially to curtail influenza-induced disease until a more appropria
133 ation and DNMT3a induction in PC12 cells and curtailed ischemic cell death (by 64 +/- 9%; p<0.05) com
135 nutrient environments engage mechanisms that curtail ketolytic capacity, controlling the utilization
141 hypothesis that extensive winter sea ice and curtailed meridional ocean overturning in the North Atla
148 D3 and CD28, this functional convergence was curtailed on surfaces in which engagement of these two s
149 a generate an initial burst of ROS, which is curtailed once mitochondria depolarize or prevented by p
150 t endogenous AMY-R transmission in the AcbSh curtails opioid function in the postprandial period, sug
151 During migration, obligate migrants can curtail or delay flights in response to inclement weathe
154 have seen this cost mount up, as resistance curtails or precludes the activities of some of our most
156 al insulin administration might be useful in curtailing overconsumption of snacks with accentuated re
157 emonstrating effectiveness of Gemcitabine to curtail pancreatic cancer and in-vivo studies failing to
158 olecules suggests that they could be used to curtail pathological processes associated with these mol
160 d protective responses against pathogens but curtails potential for causing harm to the host through
161 ely, collapse the metabolic oscillations and curtail production of reactive oxygen species and nitric
162 ease of miRNP stability in Ld-infected cells curtails production of proinflammatory cytokines, which
164 e-affected brain, but also potentially could curtail protective immune responses in the periphery.
166 pulations at sea level, in contrast with the curtailed range available to visitors at high altitudes.
167 s that the virus has evolved mechanisms that curtail rather than foster the spread of infection under
169 ption factor at the Wnt4 promoter and causes curtailed recruitment of c-Myc and p300, and histone hyp
173 iewed by many as being too restrictive, thus curtailing research, commercial development, and optimiz
174 ing T cells with two molecular mechanisms to curtail responsiveness in different biological circumsta
175 am transcriptional controller of miR-29c and curtailing REST induction prevents miR-29c down-regulati
178 ion of antero-posterior positional values is curtailed, self-organization can then produce several di
183 an increasing number of Americans choose to curtail sleep in favor of other social, leisure, or work
184 ese groups repeatedly experience chronically-curtailed sleep and demonstrate COMT-related treatment r
186 ming (OF) has been believed to be capable of curtailing some hazardous effects associated with chemic
187 a mesh whose vertices then are mapped onto a curtailed sphere; and finally moving the vertices so as
188 rigenesis, oral administration of SQ-CDDP NP curtailed spontaneous tumor formation and azoxymethane-i
192 cute stress, thereby enhancing inhibition to curtail stress-induced activation of the hypothalamic-pi
193 modest ground-state affinity is required to curtail substrate saturation and product inhibition and
194 moving SUMO from specific substrates and how curtailing sumoylation levels can regulate transcription
199 (TbetaRII(endo+/-)) mice to explore whether curtailed TGF-beta signaling significantly modifies neph
200 tate the formulation of novel therapies that curtail the accumulation of somatic expansions and may p
201 min-expressing (PV+) interneurons to rapidly curtail the activity of striatal projection neurons (SPN
202 pment and progression are urgently needed to curtail the AF epidemic and improve outcomes in affected
204 causes of sleeplessness in order to promptly curtail the chronic effects of sleep loss and effectivel
207 ivation by anti-inflammatory cytokines would curtail the duration of TCR activation and re-establish
208 ional basis for targeting the p53 pathway to curtail the effects of CTGF/CCN2 on neovessel formation
209 ial for the PA3286 shunt in P. aeruginosa to curtail the efficacy of inhibitors targeting FabY, an en
210 ether TLRs possess the reciprocal ability to curtail the extent of sterile inflammation is uncertain.
217 e ILC2/IL-13 axis as a targetable pathway to curtail the M-MDSC compartment and improve bladder cance
218 kewise, potent p110delta-specific inhibitors curtail the proliferation of GOF Shp2-expressing hematop
219 ing that the antiviral state can effectively curtail the replication of primate lentiviruses in hosts
222 many positively charged residues that could curtail the sliding due to attractive interactions with
224 transducer and activator of transcription 3) curtail the susceptibility of latently infected cells to
226 imethamine resistance in Africa threatens to curtail the therapeutic lifetime of antifolate antimalar
227 limitations of current clustering approaches curtail the types of biological network analyses that ca
228 tream Lys-63-linked deubiquitinase, strongly curtailed the ability of MLK3 to affect the proapoptotic
230 ly induced reduction of GAD65 autoreactivity curtailed the development of early T-cell responses to o
231 ere, we showed the absence of Foxo1 severely curtailed the development of Foxp3(+) regulatory T (Treg
232 murine models of obesity, DPD prevented and curtailed the development of impaired glucose homeostasi
234 inish Notch-driven colonic crypt hyperplasia curtailed the fitness advantage conferred by aerobic res
235 rget of rapamycin (mTOR) inhibitor, CCI-779, curtailed the growth of a subcutaneous challenge of mult
236 onally, SBM treatment activated macrophages, curtailed the levels of free glutathione, and augmented
237 dingly, the blockade of GC receptors in vivo curtailed the LPS-induced increase in the content of PrP
239 DNMT3a siRNA treatment also significantly curtailed the post-OGD cell death in PC12 cells (by 54 +
240 ng as a timer for cell cycle exit, p27(Kip1) curtailed the programmed expansion of interleukin-2-prod
241 expression of this short C-terminal segment curtailed the replication of influenza viruses as effect
247 des that could be utilized in monitoring and curtailing the illegal trade of these endangered species
248 uppresses production of IFN-gamma and IL-12, curtailing the innate response and its transition to ada
250 tion of beverage-only ingestive episodes and curtailing the length of the ingestion period may hold p
252 (or related molecules) could be effective in curtailing the macrophage-associated HIV-1 reservoir in
254 a critical role in inhibiting HIV infection, curtailing the pool of dNTPs available for reverse trans
255 ellular chaperones, could have a key role in curtailing the potentially pathogenic effects of the mis
256 imit the extent of NADPH oxidase activation, curtailing the production of potentially harmful reactiv
259 that increases basal energy expenditure and curtails the development of obesity, insulin resistance,
260 en deuterium pathways are inefficient, which curtails the disk's deuterated water formation and its v
261 enzymes have an important feedback role that curtails the duration of AHR signalling, but it remains
262 ly limited control associated with lower SES curtails the extent to which people can expect to realis
265 uirement to perdeuterate proteins critically curtails the potential of (1) H-detection by the loss of
267 isappearance of faunas of Burgess Shale type curtails the stratigraphic record of a number of iconic
269 g maturation undergoes sweeping changes that curtail their colocalization during the later stages of
270 ntibodies have inherent limitations that can curtail their efficacy in this setting, including poor t
271 eurons (mitral cells, MCs) that dramatically curtailed their responsiveness, suggesting a novel cellu
272 probability of spontaneous fusion events has curtailed their visualization at individual release site
273 n limited to the nanosecond temporal regime, curtailing their application in systems that require mor
279 uld exhibit adenovirus immunity, which could curtail transgene expression and therapeutic efficacy, w
282 Flicr's molecular effects are subtle, but by curtailing Treg activity, Flicr markedly promotes autoim
284 is limitation in a powerful model system has curtailed unfolding the full potential of ChR2 for behav
285 is algorithm would save institutional costs, curtail unnecessary isolation days, reduce the nosocomia
286 sensitive ATP-inactivated potassium channels curtailed VF occurrence in a porcine model of commotio c
288 I interferons is critical for strategies to curtail viral mechanisms that impede innate immune defen
289 2) prevention or delay of MI with drugs that curtail viral replication; and 3) abrogation of MI by th
290 benefits of antiretroviral therapy (ART) in curtailing viral load in HIV-infected individuals, ART d
294 (+) cells and antienvelope CD4(+) T cells in curtailing virus replication and antienvelope V1/V2 Abs
295 viruses share an Env protein with similarly curtailed VRA and VRB regions, and infection by both is
296 d the miR-29c promoter vector expression was curtailed when cotransfected with a REST expressing plas
297 lanocyte migration into the blood is somehow curtailed, whereas a significant proportion of patients
298 iety and these pathological behaviors can be curtailed with subchronic administration of a selective
299 o [a,d]-cyclohepten-5,10-imine maleate], the curtailed WT and KO responses were indistinguishable, an
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