ライフサイエンスコーパス: curvature

1 lastance increase during inflation, downward curvature).

2 oteins actively modulate the plasma membrane curvature.

3 the estimation of astigmatism than spherical curvature.

4 P proteins, consistent with loss of membrane curvature.

5 les into filaments at the inner face of cell curvature.

6 osely bound filaments of variable length and curvature.

7 hin macrophages were measured to have marked curvature.

8 eases) monotonically with increasing surface curvature.

9 adapt automatically to the local density and curvature.

10 changes in morphology induced by interfacial curvature.

11 res ranging from +50 nm to -500 nm radius of curvature.

12 ymmetrically, is predicted to favor membrane curvature.

13 he lipid membrane and the degree of membrane curvature.

14 n isotropic peak indicative of high membrane curvature.

15 ary (GB) velocity is proportional to GB mean curvature.

16 the virus quaternary arrangement and surface curvature.

17 metry with local variations in the radius of curvature.

18 localization is highly sensitive to membrane curvature.

19 pacing length and with resistance to wrinkle curvature.

20 as recruit proteins that can affect vesicle curvature.

21 gnals that are required for gravity-directed curvature.

22 and Rvs161p are known to recognize membrane curvature.

23 terogeneity in shear strength increases with curvature.

24 gments possess the ability to sense membrane curvature.

25 o areas with lower fluctuations of monolayer curvature.

26 m spin Hall system by control of its bending curvature.

27 s that varies quadratically with the bending curvature.

28 ipid bilayers than within nanoscale membrane curvature.

29 ituents have the larger negative spontaneous curvature.

30 eta-sheets using building blocks that impart curvature.

31 g, acylation significantly affected envelope curvature.

32 se in ACA was mainly owing to decreased iris curvature.

33 on with GARP2, or the generation of membrane curvature.

34 hat these tubulin heterodimers display lower curvatures.

35 ended cell sheets (SCS) of various sizes and curvatures.

36 of unknown cause, defined by abnormal spinal curvatures.

37 low (DF) occurs in arterial bifurcations and curvatures, activates endothelial cells (ECs), and resul

38 procal regulation of how the plasma membrane curvature affects the activities of endocytic proteins i

39 plant nutation, where the orientation of the curvature along the main axis of the organ aligns with t

40 ding part of the GUV-membrane exhibiting low curvature and a lack of surface contact, thus avoiding a

41 ally ligated carotids but also in the lesser curvature and branching point of the aortic arch in mice

42 -resolved pore-by-pore analysis of the local curvature and capillary pressure.

43 sical constraints, adhesive forces, membrane curvature and compaction.

44 However, exactly how membrane curvature and composition synergize remains largely unex

45 derlying biophysical mechanism dictating how curvature and composition synergize to modulate recruitm

46 This stabilizes positive curvature and decreases membrane fluidity, which inhibit

47 Z and suggest a functional link between FtsZ curvature and efficient constriction in C. crescentus.

48 these materials the interplay between Berry curvature and electron-electron interactions yields chir

49 brane-induced AH domains that alter membrane curvature and fluidity, mediating the scission of constr

50 ractility per se, promote changes to surface curvature and folding.

51 of distinctive shape, with pronounced shaft curvature and hooks of intermediate depth.

52 s 'horseshoe' lipid conformations favor such curvature and host membrane lipids that permit horseshoe

53 A flexible surface model describes how curvature and hydrophobic forces lead to the emergence o

54 Upon binding, the M2AH induces membrane curvature and lipid ordering, constricting and destabili

55 The relation between the lens curvature and material properties such as helical pitch,

56 es (numerals, words) and geometric features (curvature and real-world size).

57 PP4A activity is stimulated by high membrane curvature and synergizes with SNX9 BAR domain binding in

58 f action of acylation is to control membrane curvature and to modify HA's interaction with M1 protein

59 By finely designing the curvature and torsion, double-stranded DNA knots were ac

60 egate membrane receptors and affect membrane curvature and vesicle formation, fusion, and trafficking

61 ic minimal surfaces having negative Gaussian curvatures and can possess unusual mechanical and electr

62 Unfortunately, these high curvatures and complex forms are often difficult to manu

63 lloid-collector repulsion (reduced radius of curvature) and increased attraction (multiple points of

64 classifier (its ability to generate membrane curvature) and its maximal antimicrobial efficacy.

65 es between predictions (power-law or concave curvature) and observed empirical data (convex curvature

66 repeatability of axial length (AL), corneal curvature, and anterior chamber depth measurements of 2

67 low magnetic field strength, small radius of curvature, and high electric current mark the electron d

68 stant, the Fermi velocity, the Fermi surface curvature, and high-energy details.

69 uities, power vector of astigmatism, corneal curvature, and lens replacement frequency were obtained

70 The effects of membrane size, spontaneous curvature, and membrane stiffness on vesiculation and ve

71 ldren exhibited a narrower ACA, steeper iris curvature, and more anteriorly inserted iris than those

72 rinsic capacity to sense and induce membrane curvature, and play crucial roles for organizing and rem

73 for the correlation among domain preference, curvature, and retinotopy based on neuronal preference f

74 Outcome measures included AL, corneal curvature, and the measurement of anterior chamber depth

75 , review basic mechanisms used to sense this curvature, and then summarize the existing literature co

76 s plus-end binding, stabilizes protofilament curvature, and ultimately promotes microtubule disassemb

77 with a variety of complex shapes, cleavages, curvatures, and hierarchy.

78 e propensity by AF are negligible for higher curvature angle >90 degrees .

79 ity (i.e., 2.5-3.8 fold elevation) for lower curvature angle <90 degrees while the changes in stroke

80 large circular structures with 2.5-5 degrees curvature angles between subunits, followed by disassemb

81 refractive error, axial length (AL), corneal curvature, anterior chamber depth, lens thickness, and c

82 Complex, asymmetric curvatures are employed to enhance the performance of op

83 al features of cell shape, such as length or curvature, arise through the spatial regulation of cell

84 sults demonstrate the suitability of contour curvature as a basis for size-invariant object represent

85 We review the role of membrane curvature as a spatial cue for recruitment and regulatio

86 ree rotationally phased bent DNA of the same curvature as in a nucleosome, and that bending is modula

87 se in the deformation energy due to Gaussian curvature associated with scalloped edges, demonstrating

88 otrusions but not predominately the positive curvature associated with the tips of cellular protrusio

89 The curvature-associated morphological transition cannot be

90 quantifying the interplay between a colony's curvature at the frontier and its selection length scale

91 )D, p curvature </= 0.006), with much of the curvature attributed to a single study.

92 The average curvature (average negative DeltaCPdouble dagger) was -1

93 flying insects typically increase equatorial curvature between the front and side of the eye, which i

94 tinuum analytical methods, that the point of curvature binds an excess fractional charge and sequence

95 sable for initiation of PSM assembly and PSM curvature but required for PSM extension.

96 igated the mechanisms controlling beta-sheet curvature by studying the geometry of beta sheets in nat

97 omputational models, showing that beta-sheet curvature can be controlled with atomic-level accuracy.

98 We recently showed that membrane shape/curvature can in itself mediate the recruitment of lipid

99 Here, we show how curvature can likewise be used to control material failu

100 ric tool for controlling fracture behaviour: curvature can stimulate or suppress the growth of cracks

101 SNX9 BAR domain binding in a process we call curvature cascade amplification.

102 quires far higher protein coverage to induce curvature changes compared to those observed for the end

103 ng movement with reduced speed and transient curvature changes of the parasite.

104 gatively affected by shmoo-like positive ZCF curvature, consistent with the flattening of the ZCF dur

105 le-body exercise and (2) that the CP and the curvature constant (W') of the power-time relationship f

106 ntain rich local high-order patterns such as curvature, corners, and junctions.

107 In both APAC eyes and fellow eyes, iris curvature decreased after LPI (P < .001).

108 Here, we quantify the curvature-dependent localization of chemoreceptors in li

109 es constitute a novel tool for investigating curvature-dependent processes in live cells.

110 face-based) shapes: area, volume, thickness, curvature, depth, Laplace-Beltrami spectra, Zernike mome

111 al reconstruction microscopy), which enables curvature detection 10x faster via PLM.

112 Membrane curvature detection with PLM requires fewer localization

113 we identify and characterize CrvA, the first curvature determinant in V. cholerae.

114 f strontium titanate with a figure of merit (curvature divided by electric field) of 3.33 MV(-1), com

115 ted by an active biophysical process of cell curvature driven by the polarized distribution of xylogl

116 drolase genes pgp1 or pgp2 or a reduction in curvature due a frameshift mutation in cjj81176_1105, a

117 retical proposals further suggest that Berry curvature effects, together with strong spin-orbit inter

118 of valley magnetoelectricity driven by Berry curvature effects.

119 composition indicate that the average stored curvature elastic stress of the membrane is reduced on e

120 using geometric considerations, interfacial curvature, electrostatic interactions, partition coeffic

121 lipid-binding capacity and induces membrane curvature even in the absence of the transmembrane helix

122 is difference was characterized by a reduced curvature factor when curve fitting was used to model th

123 We recover the curvature field parameters by minimizing the objective f

124 s exhibit the same morphology, with negative curvature flanking the edges and with no visible protein

125 ture preferences for each lipid, the favored curvature for each phase, and the thermophoretic flow ar

126 of the budding virus to cause the necessary curvature for membrane scission.

127 rvature) and observed empirical data (convex curvature) for the allometric scaling of metabolic rate.

128 for lipid-protein interactions suggests the curvature force field of the membrane comes into play.

129 To quantify how curvature forms, we developed QuASAR (quantitative analy

130 e protein's C terminus may modulate membrane curvature-generating activity present in other protein d

131 gi cisterna by regulating its association to curvature-generating proteins.

132 with a concomitant dissociation of membrane curvature-generating proteins.

133 s from these distinct mechanisms to membrane curvature generation and sensing have remained controver

134 s of the helical motif up-regulated membrane curvature generation in cellulo, introducing the possibi

135 a tube attributes, such as length, width and curvature, have enabled plants to exploit many specializ

136 ions are critically sensitive to the surface curvature in both the strong- and weak-binding limits.

137 ique for the detection of nanoscale membrane curvature in correlation with single-molecule dynamics a

138 lenges in precisely controlling the membrane curvature in live cells.

139 d with released particles with flat envelope curvature in the absence of the matrix (M1) protein laye

140 properties of the filament, and the maximum curvature in the braid.

141 s have either a monotonic or a non-monotonic curvature in the observation plane of propagation, depen

142 y switch because of its negative spontaneous curvature in the target bilayer, as determined by contin

143 plex shapes, many of which exhibit elaborate curvature in three dimensions, illustrated for example b

144 CurT induces membrane curvature in vitro and is distributed all over the thyla

145 toward implementing near-arbitrary geometric curvatures in nanophotonics.

146 plasma membrane where there is micron-scale curvature, including the cytokinetic furrow and the base

147 crvA is quorum regulated, and CrvA-dependent curvature increases at high cell density.

148 d morphology as the coat area or spontaneous curvature increases, whereas the membrane remains essent

149 stigated the influence of membrane rigidity, curvature induced by the protein coat, area covered by t

150 likely arises from the significantly reduced curvature-induced frustration at the convex interfaces o

151 Because the curvature-induced stresses are independent of material p

152 Bif-1 is a membrane-curvature inducing protein that is implicated in the reg

153 t require any energy-consuming machinery, or curvature-inducing agent, or intrinsic asymmetry of the

154 te Carlo (LMC) which uses local gradient and curvature information for efficient exploration of param

155 el for the planar assembly, the induction of curvature into the RSV CA hexamer lattice arises predomi

156 gments, it appears that the ability to sense curvature involves a balance between the numbers of posi

157 present simulations suggest that aortic arch curvature is an important risk factor for embolic stroke

158 This tracheid curvature is consistent with acropetal auxin transport p

159 ivision to occur and that FzlA-mediated FtsZ curvature is correlated with efficient division.

160 ount of crowding required to induce membrane curvature is correlated with membrane tension.

161 ethod that incorporates bone intrinsic local curvature is introduced to assess the compressive failur

162 These results demonstrate that CA lattice curvature is not dependent on disorder or variability in

163 How cells recognize membrane curvature is not fully understood.

164 the limit where the protein-induced membrane curvature is of the same order as the amplitude due to t

165 ed, despite studies suggesting that membrane curvature itself can trigger biochemical reactions.

166 he time derivative of curvature, rather than curvature itself, hinting at an adaptation mechanism con

167 ior lens surface; anterior/posterior corneal curvature (K); and refraction were measured preoperative

168 and (iii) the generation of altered membrane curvature leading to aberrant recruitment of proteins.

169 e surface can dramatically increase membrane curvature, leading to fission.

170 This curvature leads to a radial variation of the optical axi

171 (ACA), iris thickness (IT), iris area, iris curvature, lens vault (LV), anterior vault, angle openin

172 tive scores for both low and high 25(OH)D, p curvature </= 0.006), with much of the curvature attribu

173 70 diopters, as measured using the sagittal curvature map that was obtained by Scheimpflug tomograph

174 l geometry at a fine level of detail through curvature measurements, yielding accurate heritability m

175 aluate the effect of misalignment on corneal curvature measurements.

176 The model further suggests that curvature-mediated filament alignment speeds up furrow c

177 the ability to target or manipulate membrane curvature might be an essential activity of proteins fun

178 dicts the sign and magnitude of the Gaussian curvature modulus that is in agreement with experimental

179 c42p focus formation depends on ZCF membrane curvature: mutant analysis showed that Cdc42p localizati

180 ells containing regions of negative Gaussian curvature naturally develop anomalously large fluctuatio

181 x more concentrated on the negative Gaussian curvature neck of the nanoscale membrane buds.

182 The tracheid curvature observed in Selaginella rhizophores provides a

183 photonics process, with a minimum radius of curvature of 100 nm.

184 associated with the lateral size and surface curvature of 2D zeolites.

185 imer formation by inducing a strong membrane curvature of approximately 100 degrees .

186 The curvature of biological membranes at the nanometer scale

187 esult of less Li consumption and much larger curvature of dendrite tips that leads to an enhanced ele

188 ell-established role in maintaining the high curvature of disc edges, and each function is fulfilled

189 rporation of Shs1 vs Cdc11, which alters the curvature of filamentous septin rings.

190 Curvature of FtsZ filaments promotes membrane deformatio

191 of Drp1 in solution as well as the preferred curvature of helical Drp1 self-assembly on membranes.

192 physin/Rvs (BAR) domain proteins control the curvature of lipid membranes in endocytosis, trafficking

193 led carbon nanotube (SWCNT) with a radius of curvature of order 10 nm results in tearing across the t

194 The spontaneous curvature of palmitate was calculated by molecular dynam

195 eting sequence (BATS) domain that senses the curvature of PtdIns(3)P-containing membrane.

196 sion was magnified more than 50 times by the curvature of space around matter in an intervening galax

197 patches of negative, zero and positive mean curvature of the air-smectic interface has a profound ef

198 ty the depth and width of which reflects the curvature of the beta-sheet segment.

199 n the behaviour of the condensate due to the curvature of the dispersion relation and the possibility

200 alisation effects may be observed due to the curvature of the dispersion relation.

201 ion by the sliding forces, regulation by the curvature of the flagellum, and regulation by the normal

202 or a phase inversion in which the preferred curvature of the interfacial surfactant layer changes it

203 flection temperature, Tinf ) and the overall curvature of the log(rate) versus temperature plot (the

204 e azobenzene moiety destroys or recovers the curvature of the main chain, which demonstrates external

205 where the SOC is predominantly caused by the curvature of the molecule's surface.

206 tification factor has a local maximum as the curvature of the nanopore surface varies, and if it is l

207 k unprecedentedly reveals that the increased curvature of the ring itself promotes its disassembly.

208 d Xenopus that the mechanisms that drive the curvature of the stomach are intrinsic to the gut tube i

209 t by local geometrical features, such as the curvature of the tissue interface.

210 envelope structure results from the extreme curvature of the viral capsid, as 'horseshoe' lipid conf

211 net increase in the recruitment by membrane curvature of tN-Ras when reducing the acyl chain saturat

212 , we found increased recruitment by membrane curvature of tN-Ras when substituting PC for PE, and whe

213 s, angles formed between adjacent cells, and curvatures of cell surfaces at gaps.

214 We provide the first evidence that it is the curvatures of maturational changes in neurophysiological

215 introduced to quantitatively predict bending curvatures of the fabricated sheets.

216 d theory, examining the dependence of ribbon curvature on blade curvature, the longitudinal load impo

217 h to investigate the systematic influence of curvature on the collective crowding or spreading of tis

218 ght, and can thereby mimic complex geometric curvatures on a flat, wavelength-scale thick surface.

219 small changes in the coat area, spontaneous curvature or membrane tension cause the membrane to "sna

220 inflation, pressure-volume curve with upward curvature) or overdistension (i.e., elastance increase d

221 The results demonstrated that curvature pattern of aorta can play a determinant role i

222 Membrane curvature, PI(4,5)P2, and PI(3)P signals are needed for

223 materials to rigid substrates with Gaussian curvature-positive for spheres and negative for saddles-

224 plore this, we looked for correlations among curvature preference, receptive field (RF) end-stopping,

225 econstitute and measure the intrinsic septin curvature preference.

226 CME endocytic protein caveolin1 show no such curvature preference.

227 urther, we found a progression in population curvature preferences along the visual hierarchy, where,

228 mong these category domains, retinotopy, and curvature preferences: for example, in inferotemporal co

229 example, in inferotemporal cortex, face- and curvature-preferring domains show a central visual field

230 with high fidelity, giving rise to membrane curvatures present in cells yet previously difficult to

231 nstrained flat elastic sheets to adopt fixed curvature profiles.

232 erC16 to modulate the membrane fluidity, its curvature propensity, and the membrane interface propert

233 ns at highly curved membrane sites through a curvature-protein coupling mechanism that supports the e

234 ormalized" curvature, rather than "absolute" curvature, provided a better account of responses.

235 The curvature radii of the biconvex lens array are in the ra

236 hroats in between of less than 29 nm, with a curvature radius r k < 14.4 nm; typical large needle-lik

237 structures to generate well-defined membrane curvatures ranging from +50 nm to -500 nm radius of curv

238 undary form: for these neurons, "normalized" curvature, rather than "absolute" curvature, provided a

239 the motors respond to the time derivative of curvature, rather than curvature itself, hinting at an a

240 ning which autophagy proteins are capable of curvature recognition.

241 ), whereas the second captured more abstract curvature-related shape features.

242 ct of the altered anterior/posterior corneal curvature relationship.

243 change in the anterior to posterior corneal curvature relationship; this needs to be taken into acco

244 ration between sites for gravity sensing and curvature response has facilitated discovery.

245 Its localization at the high-curvature rim domains of outer segment disk membranes su

246 n-2/rds functions directly to shape the high-curvature rim domains of the outer segment disk and sugg

247 of the molecular mechanisms underpinning the curvature-sensing behaviors of peptides, which will prov

248 Based on the sequences of the curvature-sensing fragments, it appears that the ability

249 The tubulin curvature-sensing model is supported by our identificati

250 provide evidence for an alternative, tubulin curvature-sensing model of microtubule depolymerization

251 the conformational entropy model to engineer curvature sensitivity into a series of multi-component s

252 alysis of multiple mutants, we conclude that curvature sensitivity is intrinsic to chemoreceptor trim

253 These proteins may act as curvature sensors, membrane benders, and scaffolding mol

254 ch will prove useful in the design of future curvature sensors.

255 edictive model incorporating HLA and corneal curvature shows greatest potential for noninvasive clini

256 CRP, but do not affect the posterior corneal curvature significantly, as measured by Scheimpflug tomo

257 ing the membrane-fusing GTPase Sey1p and the curvature-stabilizing protein Yop1p from Saccharomyces c

258 ork on its own, serving as both a fusion and curvature-stabilizing protein.

259 Sey1p also forms networks with other curvature-stabilizing proteins, including reticulon and

260 The curvature stress and hydrophobic surfaces of the all-ato

261 wn to describe the sensitivity to thickness, curvature stress, and the mechanical properties of the l

262 ver, it directly controls the sensitivity to curvature stress.

263 Isolated crystals, however, showed reduced curvature suggesting that intracellular forces bend thes

264 -dimensional phase-field model with an added curvature term successfully captures the crack's path.

265 requires fewer localization events to detect curvature than three-dimensional single-molecule localiz

266 ex patterns, such as corners, junctions, and curvature, than to their oriented line or edge component

267 ngular lattice of CA hexamers, with variable curvature that destroys the ideal symmetry of a planar l

268 , and many PIT sites showed a preference for curvature that was concave relative to fixation.

269 These nano-domains induce membrane curvature that would promote a closer contact between ve

270 uctures of dArmRP deviated from the designed curvature, the insertion of the most conserved binding p

271 the dependence of ribbon curvature on blade curvature, the longitudinal load imposed on the ribbon,

272 ical relationships between tissue growth and curvature, the role of cell density and cell vigor remai

273 assessing the contribution of FtsZ filament curvature to constriction.

274 silicon-on-insulator wafer with a deliberate curvature to form an arch shape.

275 ments could modulate the potency of membrane curvature to recruit lipidated proteins and thereby syne

276 in length, modulate the capacity of membrane curvature to recruit lipidated proteins.

277 12 +/- 4)x more concentrated on the positive curvature top and (26 +/- 11)x more concentrated on the

278 Our multidimensional small-curvature tunneling (SCT) computations indicate that, un

279 tition state theory (CVT) inclusive of small curvature tunneling (SCT) reveals the influential role o

280 riational transition state theory with small curvature tunneling), kappaSCT .

281 diate structures characterized by increasing curvature, ultimately leading to the closed-shell fuller

282 ations and was found to be comparable to the curvature values derived from VLP size distributions.

283 e measured pupil diameter, radius of corneal curvature values, central corneal thickness, WtW, ACD, L

284 l cell-membrane properties, such as membrane curvature, volume, and surface area.

285 Curvature was however apparent at higher fluence rates.

286 Previously, when such curvature was observed, concentrations in solution could

287 Phase maps helped to highlight high-curvature wavefronts and rotors.

288 gh we found no evidence for altered membrane curvature, we confirmed that daptomycin inhibits cell wa

289 functional theory and calculations of Berry curvature, we identify the Weyl points and demonstrate t

290 pported lipid bilayers on beads of different curvature, we reconstitute and measure the intrinsic sep

291 e changes in angle parameters, ACA, and iris curvature were not significantly different between the 2

292 The mechanism and function of this curvature were previously unknown.

293 flet, generating foci of enhanced charge and curvature where endophilin and synaptojanin are recruite

294 of the myosin domain in vivo disrupts tissue curvature where myosin is uniform.

295 que internal order that leads to spontaneous curvature, which allows accessing conformations that ran

296 sue deformations, including anisotropies and curvatures, which shape growing volumes and sheets of ce

297 sufficiently separated to limit spontaneous curvature while sheltering the hydrophobic sterol from t

298 Engineered hemispherical membrane curvature with a radius >/=24 nm was detected with PLM,

299 strong preference towards positive membrane curvatures with a radius <200 nm.

300 heets, and the ability to control beta-sheet curvature would allow design of binding proteins with ca