ライフサイエンスコーパス: cyanate

1 nts of OSCN(-) (hypothiocyanite) and OCN(-) (cyanate).

2 dation and preventing the formation of toxic cyanate.

3 roxidase activity was not affected by sodium cyanate.

4 ministration of 100, 200 or 300 mg/kg sodium cyanate.

5 zide or other weak acids such as formate and cyanate.

6 healthy subjects was induced with potassium cyanate.

7 hesis, SAR, and preclinical evaluation of 17-cyanated 2-substituted estra-1,3,5(10)-trienes as antica

8 Sodium cyanate, a neurotoxic chemical in rodents, primates and

9 Cyanate, a reactive electrophilic species in equilibrium

10 Cyanate, a reactive species in equilibrium with urea, ca

11 ; but rather (3) that urea, via breakdown to cyanate and ammonium ions, may cause cell stress because

12 r ring by treatment with beta-ethoxyacryloyl cyanate and cyclization to form the uracil ring.

13 ep involves a carbamylation reaction between cyanate and the nascent alpha amino group resulting from

14 bstituent groups R in heteroatom-substituted cyanates and thiocyanates RX-YCN and the isomeric isocya

15 ilyl azide or isocyanate or potassium azide, cyanate, and bromide) to yield unstable hypervalent iodi

16 and ions, notably carbon monoxide, cyanide, cyanate, and hydrogen sulfide, are potent inhibitors of

17 pe involve the HOMO of a nearly linear (thio)cyanate anion and the LUMO of the acyl cation, in partic

18 A range of substrates has furnished cyanated azaindoles in good to excellent yields under th

19 odynamic potential--EPR spectra confirm that cyanate binds selectively to C(red2).

20 Their dependencies on pH and azide or cyanate concentrations are consistent with both earlier

21 ing reactions with dialkynes, while the (iso)cyanate-containing polymers reacted with diamines to aff

22 hydrolysis product, cyanoacetaldehyde), with cyanate, cyanogen, or urea.

23 Sodium cyanate depleted GSH levels in all regions of mouse brai

24 action of cysteine sulfhydryls with residual cyanate derived from urea.

25 KC8 reduction of 3 resulted in cyanate dissociation to give [U(Tren(TIPS))] (4) and KNC

26 llustrated using agarose supports containing cyanate ester, N-hydroxy-succinimide, and epoxy function

27 ve and quantitatively dominant mechanism for cyanate formation and protein carbamylation at sites of

28 combination of NMR and IR spectroscopy, and cyanate formation was further confirmed by performing a

29 grating R group and the neighboring iso(thio)cyanate function.

30 ous amino ester hydrochlorides and potassium cyanate in a planetary ball-mill is described.

31 to generate V(N[t-Bu]Ar)(3) (1-V) and sodium cyanate in an isolated yield of 77%.

32 tissue GSH/GSSG ratios, likely results from cyanate-induced inhibition of glutathione reductase acti

33 rovide a direct source of isocyanic acid and cyanate ion (NCO(-)) to humans at levels that have recog

34 active intermediates, such as free radicals, cyanate ions, and isocyanic acid, which can form cross-l

35 (3) Cyanate is a strong inhibitor of CO(2) reduction but inh

36 of aryl chlorides and triflates with sodium cyanate is reported.

37 scopy, fluorescence from fluorescein isothio-cyanate-labeled FN-oligonucleotides was detected in reti

38 ximately thiocyanate approximately nitrate < cyanate < azide < fluoride << cyanide.

39 Cyanate modification of the lysines in model alpha-helix

40 , is chemically masked with an electrophilic cyanate motif in order to construct a fluorescent probe

41 The molecular and cellular mechanisms of cyanate neurotoxicity are not understood.

42 The results of this study suggest that cyanate neurotoxicity, and perhaps cassava-associated ne

43 Recent studies suggest that cyanate (OCN(-)) is a potentially important source of re

44 addition to N3(-), thiocyanate ((-)SCN) and cyanate ((-)OCN) anions were also studied.

45 avity (e.g.: fluoride, F(-); cyanide, CN(-); cyanate, OCN(-); thiocyanate, SCN(-); and nitrate, NO(3)

46 This study investigates the effect of sodium cyanate on glutathione (GSH) homeostasis in rodent brain

47 Addition of the weakly acidic anions azide, cyanate, or formate accelerates the decay of the O inter

48 . pasteurianum was activated by thiocyanate, cyanate, or sulfhydryl compounds; inhibited by sulfite,

49 Acyl-, alkoxycarbonyl-, and carbamoyl cyanates R-CO-OCN are predicted to be in some cases isol

50 ing N-cyano-N-phenyl-p-toluenesulfonamide as cyanating reagent in the presence of AgOTf and NaOAc in

51 Employing the electrophilic cyanating reagent N-cyano-N-phenyl-p-toluenesulfonamide

52 repare aryl nitriles by using a carbon-bound cyanating reagent which undergoes cross-coupling with th

53 sily accessible and environmentally friendly cyanating reagent, NCTS.

54 ion to give [U(Tren(TIPS))] (4) and KNCO, or cyanate retention in [U(Tren(TIPS))(NCO)][K(B15C5)2] (5,

55 The strategy is based on a [3,3]-allyl cyanate sigmatropic rearrangement from enantioenriched g

56 f 2-phenylpyridine derivatives and potassium cyanate through C-H bond functionalization in the presen

57 -allenyl rearrangement, conversion of benzyl cyanates to o-isocyanatotoluenes, and conversion of N-cy

58 is based on enzymatic kinetic resolution and cyanate-to-isocyanate rearrangement as key steps.

59 The key step is stereospecific allyl cyanate-to-isocyanate rearrangement, which proceeds with

60 The key step is allyl cyanate-to-isocyanate rearrangement.

61 ha-tertiary allylamines via stereocontrolled cyanate-to-isocyanate sigmatropic rearrangement reaction

62 H2CH2NSiiPr3)3) with CO gave the uranium(IV) cyanate [U(Tren(TIPS))(NCO)] (3).

63 le for the conversion of azide to nitride to cyanate using 4, NaN3 and CO is presented.

64 Reaction of cyanate with the alpha-amino group of hemoglobin (HbOCN)