ライフサイエンスコーパス: cyanine

1 yene cations and dyes such as indigo and the cyanines.

2 ed C4'-dialkylamine-substituted heptamethine cyanines.

3 ear optical properties analogous to those of cyanines.

4 The J-aggregation of Cyanine-1dye in the presence of carboxymethyl amylose (C

5 initial donor for energy transfer with both Cyanine 3 (Cy3) and Alexa Fluor 647 (A647) fluorescent d

6 Here we report that small molecules, such as cyanine 3 (Cy3), a synthetic fluorescent molecule, and 4

7 One reporter is modified with cyanine 3 (Cy3), whereas the other is modified with a sp

8 uorescence resonance energy transfer between cyanine 3 and 5 terminally attached to duplex species ex

9 ines, were each combined with fluorescently (cyanine 3) labeled universal reference mRNA.

10 Conjugation of the fluorescent probe cyanine 5 at their focal point via click chemistry permi

11 eavage, induced by targeted enzymes leads to Cyanine 5 signal enhancement, which is finally quantifie

12 Fluorescently (cyanine 5) labeled cDNA probes, made individually from m

13 Fluorescently (cyanine 5) labeled normal pancreas mRNA was also compare

14 Atto467N (emitting at the same wavelength as cyanine 5, Cy5) were found to bleach significantly less

15 tinct acceptor fluorophores, fluorescein and cyanine 5, to label of NCoR and SRC3, respectively, we h

16 sures intensity of marker expression using a cyanine 5-conjugated antibody within the mask.

17 Using cyanine 5.5-superparamagnetic iron oxide nanoparticle (C

18 s labeled with the fluorophore/quencher pair Cyanine 5/BHQ2.

19 tation wavelength and emission wavelength of Cyanines 5 (Cy5), was used to amplify the fluorescence s

20 al resonance at the excitation wavelength of cyanine-5 (Cy5), thus providing an increase in fluoresce

21 ed that the probe incorporating a sulfonated cyanine-5 fluorophore was the most appropriate for imagi

22 robe was synthesized by covalently attaching cyanine 7 (Cy7), a near-infrared cyanine dye, to tilmano

23 -99m ((99m)Tc)-labeled TCP-1 and fluorescent cyanine-7 (Cy7)-labeled form of the peptide (Cy7-TCP-1).

24 overlap of the PPESO3 fluorescence with the cyanines' absorption.

25 tes 1a-1c consisting of a BODIPY donor and a cyanine acceptor were prepared using a simple synthetic

26 that the photoconversion product is a thiol-cyanine adduct in which covalent attachment of the thiol

27 No cyanine aggregation was observed in organic solvents or

28 Two novel fluorescent cyanine-AMP conjugates, F550/570 and F650/670, have been

29 arly all organic fluorophores, including the cyanine and Alexa dyes.

30 the fluorescence and FRET behaviors of both cyanine and Alexa fluorophores.

31 c structures consist of a positively charged cyanine and negatively charged dienolate moieties, confi

32 h, we demonstrate the correspondence between cyanines and the new class of alkyne carbocations, in sp

33 The preparation of cyanine antibody conjugates, drug cleavage mediated by 6

34 stain SYBR Safe indicates that it contains a cyanine-based cationic core structure identical to thiaz

35 Two-photon photoconversion of cyanine-based dyes offer several advantages over existin

36 nter cells upon coincubation and contain two cyanine-based fluorescent reporters covalently bound to

37 rall, this paper reports readily accessible, cyanine-based through-bond ET cassettes that are lypophi

38 We report that cyanine-based, organic dyes can be efficiently photoconv

39 Anionic and cationic cyanines can be organized into complementary cyanine sal

40 A cyanine-class near-infrared fluorescent dye, Cy7, and do

41 Our previous work found trimethine cyanine compounds that effectively inhibit PRMT1 activit

42 isualized with fluorescence microscopy using cyanine-conjugated and fluorescein-conjugated secondary

43 visualized by fluorescence microscopy using cyanine-conjugated and fluorescein-conjugated secondary

44 Hybridization signals were visualized with cyanine (Cy)-5 or Cy-3 fluorescent reporter molecules, a

45 dyes (termed dyedrons) comprised of multiple cyanine (Cy3) donors coupled to a single malachite green

46 t labeling of lysine groups on proteins with cyanine CyDye DIGE Fluor minimal dyes before isoelectric

47 idic media with the generation of a deep red cyanine derivative, absorbing at 537 nm, which is visibl

48 SYBR Green 1 is an asymmetrical cyanine DNA-binding dye that provides an opportunity for

49 n allowed the conjugation with a fluorescent cyanine dye (Cy5) and biotin, resulting in binding K(i)

50 and MeHg(+) -responsive near-infrared (NIR) cyanine dye (hCy7) for MeHg(+) detection within living s

51 all the dyes studied relative to a benchmark cyanine dye (ICG) during photoexcitation with exceptiona

52 Herein we utilize cyanine dye 3,3'-diethyl-9-methyl-thiacarbocyanine iodid

53 tact and were detected using the symmetrical cyanine dye 3,3'-diethylthiadicarbocyanine iodide (DiSC2

54 ansferred through an acetylene bridge to the cyanine dye acceptor, which emits light at approximately

55 tion of densely packed, discrete clusters of cyanine dye aggregates with tunable absorption spectra a

56 ormation of an encounter complex between the cyanine dye and ionized thiol prior to their conjugation

57 to study the interaction between a cationic cyanine dye and peptide nucleic acid (PNA)-DNA duplexes.

58 enching of a conjugated polyelectrolyte by a cyanine dye are investigated by femtosecond fluorescence

59 his is the first demonstration of an encoded cyanine dye as a ncAA in a eukaryotic expression system

60 at combines a rhodium metalloinsertor with a cyanine dye as the fluorescent reporter.

61 Overall, a cyanine dye can dissociate aggregated Tau in an ex vivo

62 Solution and solid-phase syntheses of a cyanine dye conjugated to polystyrene beads (desired for

63 We report that the cyanine dye Cy5 and several of its structural relatives

64 BLM, deglycoBLM, and BLM disaccharide to the cyanine dye Cy5**.

65 assay, and in vivo optical imaging using the cyanine dye Cy5.5 conjugate.

66 probe (TRAP) consisting of a monosubstituted cyanine dye derivatized with arsenic (i.e., TRAP_Cy3) to

67 layed library for binding to the fluorogenic cyanine dye Dimethyl Indole Red (DIR).

68 We have used a cyanine dye family as a paradigm and high-resolution cap

69 ry oligonucleotides were conjugated with the cyanine dye fluorophores Cy3 and Cy5 to quantify the mel

70 A new asymmetric, squarylium cyanine dye functionalized by boronic acid ("SQ-BA") was

71 d the photophysics of the series and monomer cyanine dye have been studied in solution.

72 ons from PbS QDs by adsorbed J-aggregates of cyanine dye in aqueous dispersions.

73 is observed from J-aggregates of the achiral cyanine dye in association with a random coil CMA, sugge

74 Although cyanine dye loading is often accompanied by fluorescence

75 estigated for polyelectrolytes consisting of cyanine dye pendant polylysines ranging in number of pol

76 The influence of the DNA target and probe cyanine dye position on oligo-DNA duplex formation behav

77 YTOX Green stain is a cationic unsymmetrical cyanine dye that is excluded from live cells but can rea

78 We have developed a new unsymmetrical cyanine dye that overcomes this problem.

79 The cyanine dye thiazole orange (TO) is a well-known fluorog

80 A symmetrical cyanine dye was previously shown to bind as a cofacial d

81 Therefore, the heptamethine cyanine dye will be an attractive scaffold to create a s

82 sensor 790 combines a near-infrared emitting cyanine dye with a sulfur-rich receptor to provide a sel

83 on between DNA and a benzothiazole-quinoline cyanine dye with a trimethine bridge (TO-PRO-3) results

84 labeling method using ISEL combined with the cyanine dye YOYO-1 that binds to DNA.

85 erated photobleaching of the light-sensitive cyanine dye, 3,3'-diethylthiacarbocyanine iodide (DiSC(2

86 re examined: Rhodamine 6G, crystal violet, a cyanine dye, and a cationic donor-acceptor substituted s

87 lipid-specific since inclusion of a cationic cyanine dye, DiIC18(3), to impart positive charge in pla

88 amer selected for binding to the fluorogenic cyanine dye, dimethylindole red (DIR), also binds and ac

89 y attaching cyanine 7 (Cy7), a near-infrared cyanine dye, to tilmanocept, a radiopharmaceutical that

90 Receptor-bound, cyanine dye-labeled ligands, [Cy]ligands, were discrimin

91 d to adjust the extent of aggregation of the cyanine dye.

92 model the trans-cis isomerization of a model cyanine dye.

93 um, including a near-infrared (NIR)-emitting cyanine dye.

94 plays an induction period unlike that of the cyanine dye.

95 ine kinase c-Met conjugated to a fluorescent cyanine dye.

96 d with increasing DS (of CMA), rendering the cyanine dye/CMA complex a more rigid (a high fluorescenc

97 ans of Stark effect in planar heterojunction cyanine dye/fullerene organic solar cells enables one to

98 Here, we show that, when cyanine-dye labeled 2'-deoxy and 2'-O-methyl oligonucleo

99 's complexity: cylinders self-assembled from cyanine-dye molecules.

100 Similar cyanine dyes (DiSC(3)(3), DiSC(4)(3), DiSC(5)(3), and Di

101 Other cyanine dyes (e.g., Cy3, Alexa 555) were not significant

102 data that show susceptibility of a class of cyanine dyes (e.g., Cy5, Alexa 647) to ozone levels as l

103 e-shell nanoparticles that encapsulated with cyanine dyes and applied the dye-doped nanoparticles as

104 ocavities containing two spatially separated cyanine dyes are presented here, where simultaneous stro

105 Unsymmetrical cyanine dyes are widely used in biomolecular detection d

106 ntum dot-quantum rods (QD-QRs) as donors and cyanine dyes as acceptors, which are conjugated to QD-QR

107 terature survey indicated no previous use of cyanine dyes as contrast agents for in vivo optical dete

108 ed for the site-specific genetic encoding of cyanine dyes as non-canonical amino acids (Cy-ncAAs) int

109 Previous studies have utilized cyanine dyes as Tau aggregation inhibitors in vitro.

110 , monofunctional, water-soluble heptamethine cyanine dyes containing a robust C-C bond at the central

111 dure to the synthesis of otherwise difficult cyanine dyes containing multiple heteroatoms in the indo

112 Cyanine dyes have been shown to undergo reversible photo

113 nding of structure-property relationships in cyanine dyes is critical for their design and applicatio

114 the corresponding electronic potential makes cyanine dyes the compounds to which simple free-electron

115 le fragment antibody protein and a family of cyanine dyes to create new protein-dye fluoromodules tha

116 beling methodology that uses platinum-linked cyanine dyes to directly chemically label mRNA from as l

117 nsfers the pH sensitivity of photolabile NIR cyanine dyes to highly emissive and long-lifetime pH-ins

118 amplified quenching of PPESO3 by a series of cyanine dyes via singlet-singlet energy transfer.

119 phenyl-, and phenyl-substituted heptamethine cyanine dyes were prepared by a modified Suzuki--Miyaura

120 h high affinity to several other fluorogenic cyanine dyes with emission wavelengths covering most of

121 lass of NIR fluorescent dyes, pyrrolopyrrole cyanine dyes, have exceptionally long FLTs ranging from

122 The binding interactions between two cyanine dyes, pseudoisocyanine (PIC) and pinacyanol (PIN

123 were obtained for host-guest films using two cyanine dyes, reaching 27%.

124 and higher emission rates than commonly used cyanine dyes.

125 d by PCR, and the products were labeled with cyanine dyes.

126 -helix DNA-binding motifs with intercalating cyanine dyes.

127 DNA constructs labeled with cyanine fluorescent dyes are important substrates for si

128 4-nitrobenzyl alcohol (NBA) or Trolox to the cyanine fluorophore Cy5 dramatically enhanced fluorophor

129 ly unexploited photochemical reaction of the cyanine fluorophore scaffold.

130 ed as ca. 20 pM (equivalent to 10 zmol) of a cyanine fluorophore, Cy5.

131 Cyanine fluorophores are commonly used in single-molecul

132 Far-red cyanine fluorophores find extensive use in modern micros

133 nal stacking is an intrinsic property of the cyanine fluorophores irrespective of the length of the t

134 port the synthetic variation of pentamethine cyanine fluorophores with modifications of physicochemic

135 nd through meso-substitution of pentamethine cyanine fluorophores.

136 Antagonist activity depended on cyanine heterocycle, polymethine bridge length, and the

137 ucture-activity relationship for symmetrical cyanine inhibitors of human tau aggregation was elaborat

138 HF6/PH6* hexapeptide motifs, indicating that cyanine interacted with a species in the aggregation pat

139 yanine Cy7 or, alternatively, a heptamethine cyanine IRDye 800CW) that were linked at the positions +

140 s via Forster resonance energy transfer from cyanine J-aggregates.

141 By titrating DB270 and/or cyanine-labeled DNA with protein or unlabeled DNA, and f

142 he very small reorganization energy in these cyanine-like chromophores.

143 of the third-order polarizability (gamma) of cyanine-like molecules through incorporation of polariza

144 amer, display conjugated structures near the cyanine limit of bond length equalization as a result of

145 itting electrochemical cells (LECs) based on cyanine molecules were prepared.

146 red (DIR), also binds and activates another cyanine, oxazole thiazole blue (OTB), giving two well-re

147 on the nature of the dye pair used, with the cyanine pair Cy3-Cy5 showing the least amount of fluctua

148 -dioctadecyl-3,3,3',3'-tetra-methylindocarbo-cyanine perchlorate (DiI) was applied via tracheal insti

149 '-dioctadecyl-3,3,3',3'-tetramethylindocarbo-cyanine perchlorate (DiI) was used to label selectively

150 dioctadecyl-3,3,3',3'-tetramethylindodicarbo-cyanine perchlorate.

151 elating the ground state polarizabilities of cyanine, phenothiazine, and arylmethine derivatives calc

152 resonance energy transfer (FRET), and loaded cyanine probe (e.g., 1,1-dioctadecyl-3,3,3,3-tetramethyl

153 lors by covalently linking a photoswitchable cyanine reporter and an activator molecule to assist bio

154 cyanines can be organized into complementary cyanine salts, offering potential building blocks to mod

155 Measurement of the time dependence of cyanine staining of pores shows fluctuations of fluoresc

156 gated the structure-activity relationship of cyanine structures.

157 Further, as is the case with many cyanines, the dye suffers from low photostability.

158 modified by (a) electronic tuning along the cyanine-type axis via modification of the donor-acceptor

159 etermined by the electronic structure of the cyanine-type backbone (approach (a)).

160 issense mutants as targets, interaction with cyanine was localized to the microtubule binding repeat

161 The photophysical behavior of the cyanines was investigated using UV-vis and steady-state

162 New cyanines were prepared by an efficient and practical rou

163 Cyanines, which represent a class of charged chromophore

164 are based on rhodamines, carbopyronines and cyanines with excellent photophysical properties, that i