ライフサイエンスコーパス: cyano group

1 e ring opening, the unusual migration of the cyano group.

2 han phenolic substrates due to the aliphatic cyano group.

3 eraction observed in this study was with the cyano group.

4 s that are activated by electron-withdrawing cyano groups.

5 ly 5:1) in favor of the proximal methoxy and cyano groups.

6 metacyclophanediene 1 is diprotonated at the cyano groups (1H2 2+) in various superacid media.

7 Without the cyano group, acid 26 and xanthate 27 were found to be mo

8 ion of a hydrophobic substituent next to the cyano group and aminoquinoline methylation considerably

9 ubstitution of the guanidine group with an N-cyano group and replacement of guanidine with amidine, p

10 hydrogen bonding interactions involving the cyano group and residue 751 in the ATP site.

11 eactive azadienophiles including unactivated cyano groups and heterosubstituted imine derivatives suc

12 t a 3(R)-phenylmethyl group, a hydrophilic 7-cyano group, and a 4-sulfonyl group bearing a variety of

13 hydrogen bonding interactions involving the cyano group, and its fluorescence quantum yield increase

14 -propenylcuprate at C4 and introduction of a cyano group as a carboxylic acid equivalent at C2.

15 s featuring the participation of unactivated cyano groups as enophile and dienophile cycloaddition pa

16 A new 1,4-dihydropyridine 5a, containing a cyano group at the C3 position, was recently reported to

17 nship perspective, the new abietane 5 having cyano groups at C-2 and C-13 and a phenolic ring C has b

18 ion further enhanced activity with methyl or cyano groups being preferred at the 2-position.

19 e, the replacement of the carbon atom in the cyano group by an isovalent silicon atom has a pronounce

20 is bound in the P1 binding site and that the cyano group can act as a H-bond acceptor for the amide p

21 The cyano group enhances binding by several orders of magnit

22 bind to the catalytic site of DPPIV with the cyano group forming a covalent bond with the serine resi

23 correlation was obscured by the transfer of cyano groups from modified to unmodified cysteines durin

24 n of the peptide/protein upon removal of the cyano groups from the derived bisthiocyanate.

25 observation that NHC-boryl radicals abstract cyano groups from various organic nitriles has been parl

26 Intramolecular carbopalladation of the cyano group has been employed for the synthesis of 3,4-d

27 lpalladium species to the triple bond of the cyano group, have been studied.

28 presence of a powerful electron-withdrawing cyano group in compound 5d expectedly produced the most

29 ine 5 to a dinitrile 7, 8, or 9 with the two cyano groups in 1,3 or 1,4 distance.

30 ic group in the 4 position is coupled with a cyano group, in one case, and the dimethylamino group in

31 scribe an analogue of dZ (cyano-dZ) having a cyano group instead of a nitro group, including its synt

32 Iterative transformation of the 5-cyano group into an amidine allows synthesis of 2,5-terp

33 molecular dynamics simulations show that the cyano group is exposed to solvent and forms hydrogen bon

34 triple bond]N) fluorescence is high when the cyano group is hydrogen bonded and low when it is not.

35 Hydrogen bonding to the cyano group is known to play a major role in modulating

36 The more strongly electron-accepting cyano group is predicted to shift the transitions of dia

37 Replacement of the iminium motif by a cyano group is well tolerated and gives an additional de

38 (2) The cyano group leads to an increase in the acidities but to

39 ximum rates confirm that sequestering of the cyano groups occurs concomitantly with the development o

40 tional group transformations involving the 5-cyano group of 4 furnished the 5-carboxamide derivatives

41 aziridine ring opening, interaction with the cyano group of cyanoaziridines, or opening of the iminop

42 YP) is responsible for the conversion of the cyano group of pinacidil to the corresponding amide.

43 lized the orientation of the electronegative cyano group of the hapten.

44 2)=Y(-) + CH(3)Y, i.e., on the effect of the cyano group on acidities, proton-transfer barriers, and

45 Introducing an electron-deficient p-cyano group on the B-phenyl substituent creates a twiste

46 the fact that the stabilizing effect of the cyano group on the transition state is greater than that

47 = alkyl, protected aldehyde, aminocarbonyl, cyano groups, or isoxazole ring) with thiol salts were i

48 rmation on the rubbed surface, and the polar cyano groups point down toward the layer surface deduced

49 lectivity are mediated by the binding of the cyano group to a new auxiliary pocket in nNOS.

50 romophore containing an electron-withdrawing cyano group to delocalize negative charge from the chrom

51 ich then undergo smooth cycloaddition with a cyano group to generate the desired fused 1,2,3-triazole

52 rformance is further enhanced by introducing cyano groups to the CoPc molecule.

53 rated that C-H bonds can be activated by the cyano group under high pressure, but at room temperature

54 mide, hydrazine and methylhydrazine to the 5-cyano group was carried out to give the corresponding an

55 nced binding for inhibitors containing the m-cyano group was observed for coagulation factor Xa and f

56 Two azidoneonicotinoids with a nitro or cyano group were compared with the corresponding desnitr

57 An allyl and a cyano group were introduced into the resulting adduct by

58 mma (PPARgamma), whereas analogs without the cyano group were weakly cytotoxic and did not activate P

59 alization at the 2-position, adjacent to the cyano group, when the 4-subsitutent is larger than cyano

60 where the water molecule is displaced by the cyano group which interacts with the same Thr residue.

61 of TO is replaced by an electron withdrawing cyano group, which was expected to decrease the suscepti

62 formed by combining the electron-withdrawing cyano group with thiophene or benzothiadiazole units.

63 , a(u), b(1g), and b(2u), all located at the cyano group) with pi*-orbitals of the ring systems.