ライフサイエンスコーパス: cyclic AMP-dependent protein kinase

1 a phosphorylation by protein kinase C or the cyclic AMP-dependent protein kinase.

2 n their dependence on the signaling effector cyclic AMP-dependent protein kinase.

3 by beta-adrenergic receptors, cyclic AMP and cyclic AMP-dependent protein kinase.

4 atory subunit of protein kinase A (PKA), the cyclic AMP-dependent protein kinase.

5 isons to the crystallographic structure of a cyclic AMP-dependent protein kinase.

6 hares a common conserved catalytic core with cyclic AMP-dependent protein kinase.

7 higher concentrations, and does not inhibit cyclic AMP-dependent protein kinase.

8 tor [PKI(5-24)] and ATP-binding sites in the cyclic-AMP-dependent protein kinase.

9 e A and site B in the regulatory subunits of cyclic AMP-dependent protein kinases.

10 By using cyclic AMP-dependent protein kinase (1CDK) as a template

11 rophy protein kinase (DM-PK), as well as the cyclic AMP-dependent protein kinase (33%).

12 bitory cyclic nucleotide signaling involving cyclic AMP-dependent protein kinase A (PKA) and cyclic G

13 ippocampus (<9 postnatal days, <P9) requires cyclic AMP-dependent protein kinase A (PKA) but not Ca(2

14 ce lacking the RIIbeta regulatory subunit of cyclic AMP-dependent protein kinase A (PKA) display redu

15 ion methods were used to examine the role of cyclic AMP-dependent protein kinase A (PKA) in regulatin

16 re we report that HDAC8 is phosphorylated by cyclic AMP-dependent protein kinase A (PKA) in vitro and

17 We further show that the cyclic AMP-dependent protein kinase A (PKA) is essential

18 Here, we show that cyclic AMP-dependent protein kinase A (PKA) phosphorylat

19 perilipin A (Peri A) mediates the actions of cyclic AMP-dependent protein kinase A (PKA) to stimulate

20 he regulatory subunit (R(I)alpha(94-244)) of cyclic AMP-dependent protein kinase A (PKA) were probed

21 essed by prostaglandin E(2) (PGE(2)) and the cyclic AMP-dependent protein kinase A (PKA).

22 re, however, recent data have implicated the cyclic AMP-dependent protein kinase A as a negative regu

23 press a constitutively activated form of the cyclic AMP-dependent protein kinase A catalytic subunit

24 c28, and Som1, a downstream regulator of the cyclic AMP-dependent Protein Kinase A pathway.

25 gulation of survivin by CB1 is mediated by a cyclic AMP-dependent protein kinase A signaling pathway.

26 brates, such as hairy, hedgehog, patched and cyclic AMP-dependent protein kinase A, are responsible f

27 adrenergic receptors activates type I and II cyclic AMP-dependent protein kinase A, resulting in phos

28 lear expression is enhanced by inhibition of cyclic AMP-dependent protein kinase A.

29 , encoding the R1alpha regulatory subunit of cyclic-AMP-dependent protein kinase A, are the cause of

30 hippocampal neurons enhances the activity of cyclic AMP-dependent protein kinase, a key molecule that

31 pha(s), independent of adenylate cyclase and cyclic AMP-dependent protein kinase activation.

32 expression and was inhibited by unregulated cyclic AMP-dependent protein kinase activity like ADH2 e

33 an (PLB) can be phosphorylated at Ser(16) by cyclic AMP-dependent protein kinase and at Thr(17) by Ca

34 essed in baculovirus are substrates for both cyclic AMP-dependent protein kinase and autophosphorylat

35 Balanol is a potent inhibitor of cyclic AMP-dependent protein kinase and protein kinase C

36 that Ser-563 of rat HSL is phosphorylated by cyclic AMP-dependent protein kinase and that Ser-565 is

37 a protein of unknown function that binds to cyclic AMP-dependent protein kinase and the peripheral b

38 A-kinase anchoring proteins (AKAPs) tether cyclic AMP-dependent protein kinases and thereby localiz

39 re selective inhibitors of protein kinase C, cyclic AMP-dependent protein kinase, and cyclic GMP-depe

40 , and phosphorylation by CKII, cdc2, PKC-xi, cyclic AMP-dependent protein kinase, and ecto-protein ki

41 us in vitro phosphoryl transfer assays using cyclic AMP-dependent protein kinase as a representative

42 amphipathic helix of AKAPs are required for cyclic AMP-dependent protein kinase binding, with the si

43 XEEK1 is a substrate for the cyclic AMP-dependent protein kinase both in vitro and in

44 was significantly inhibited by activation of cyclic AMP-dependent protein kinase by forskolin.

45 yclic GMP-dependent protein kinase (cGK) and cyclic AMP-dependent protein kinase (cAK) contain two di

46 ly blocked by intracellular injection of the cyclic AMP dependent protein kinase (cAMP-PK) regulatory

47 ssumed to be cyclic AMP-dependent and due to cyclic AMP-dependent protein kinase (cAPK) activation ba

48 In Saccharomyces cerevisiae, the unregulated cyclic AMP-dependent protein kinase (cAPK) activity of b

49 e binding first is unique to p38 compared to cyclic AMP-dependent protein kinase (cAPK) and most tyro

50 ified derivative of the catalytic subunit of cyclic AMP-dependent protein kinase (cAPK) whose fluores

51 Cyclic AMP-dependent protein kinase catalyzed the incorp

52 Phosphorylation of isoform A by the cyclic AMP-dependent protein kinase caused a 2.5-fold in

53 Serine 87, a cyclic AMP-dependent protein kinase consensus site locat

54 Cyclic-AMP-dependent protein kinase-defective pituitarie

55 utyryl cyclic AMP) nor an inhibitor (H89) of cyclic AMP-dependent protein kinase had any effect on FP

56 tion of the transporter, excluding a role of cyclic AMP-dependent protein kinase in hPGT regulation.

57 effective substrate for catalytically active cyclic AMP-dependent protein kinase in vitro.

58 modulin, phosphorylation of isoform A by the cyclic AMP-dependent protein kinase increased activity 1

59 via phosphorylation-dephosphorylation, with cyclic AMP-dependent protein kinase increasing activity

60 Cyclic AMP-dependent protein kinase is tethered to prote

61 ss of multiple prostate cancer cell lines by cyclic AMP-dependent protein kinase-mediated actions.

62 Large changes in activity are linked to cyclic AMP-dependent protein kinase-mediated phosphoryla

63 eptor and provide a molecular explanation of cyclic AMP-dependent protein kinase-mediated repression

64 ylation of synapsin Ia at serine 9 by either cyclic AMP-dependent protein kinase or p21-activated pro

65 Phosphorylation of the catalytic subunit of cyclic AMP-dependent protein kinase, or protein kinase A

66 The cyclic AMP-dependent protein kinase phosphorylated the i

67 n the current study, a putative second AANAT cyclic AMP-dependent protein kinase phosphorylation site

68 Cyclic AMP dependent protein kinase (PKA) is controlled,

69 v-Mos as Ser-56, which is phosphorylated by cyclic AMP dependent protein kinase (PKA).

70 We investigated the effect of cyclic AMP-dependent protein kinase (PKA ) on v-Mos kina

71 ecently demonstrated that inhibition of host cyclic AMP-dependent protein kinase (PKA) activity negat

72 channels, which requires phosphorylation by cyclic AMP-dependent protein kinase (PKA) anchored via a

73 (V)1.1) activity requires phosphorylation by cyclic AMP-dependent protein kinase (PKA) anchored via a

74 Activated cyclic AMP-dependent protein kinase (PKA) and Akt are do

75 Cyclic AMP-dependent protein kinase (PKA) and members of

76 The 3'-5' cyclic AMP-dependent protein kinase (PKA) and serine 312

77 ion mutant beta(2)AR (PKA(-)) that lacks the cyclic AMP-dependent protein kinase (PKA) consensus phos

78 The dimerization/docking (D/D) domain of the cyclic AMP-dependent protein kinase (PKA) holoenzyme med

79 We have investigated the involvement of cyclic AMP-dependent protein kinase (PKA) in LTP by dire

80 l on IL-1beta-induced NO production; H-89, a cyclic AMP-dependent protein kinase (PKA) inhibitor, ant

81 bited by wortmannin (100 nm), but not by the cyclic AMP-dependent protein kinase (PKA) inhibitor, H89

82 Cyclic AMP-dependent protein kinase (PKA) is anchored at

83 viously described form of LTD, activation of cyclic AMP-dependent protein kinase (PKA) is necessary a

84 In cancer cells, cyclic AMP-dependent protein kinase (PKA) is secreted in

85 (AC6-WT) or an AC6 mutant lacking a PKC and cyclic AMP-dependent protein kinase (PKA) phosphorylatio

86 Activation of cyclic AMP-dependent protein kinase (PKA) results in the

87 Dephosphorylation of the cyclic AMP-dependent protein kinase (PKA) site phosphose

88 One of the cyclic AMP-dependent protein kinase (PKA) substrates in

89 Cyclic AMP-dependent protein kinase (PKA) targets contra

90 AKAP79 complex are involved in targeting the cyclic AMP-dependent protein kinase (PKA) to the beta(1)

91 Protein phosphorylation by cyclic AMP-dependent protein kinase (PKA) underlies key

92 stimulated lipolysis occurs by activation of cyclic AMP-dependent protein kinase (PKA) which phosphor

93 We find that activation of cyclic AMP-dependent protein kinase (PKA) with forskolin

94 nd contains a conserved recognition site for cyclic AMP-dependent protein kinase (PKA), corresponding

95 SHIP1 can be phosphorylated by the cyclic AMP-dependent protein kinase (PKA), resulting in

96 LNCaP cells with agents that signal through cyclic AMP-dependent protein kinase (PKA), such as epine

97 Activators of cyclic AMP-dependent protein kinase (PKA), such as PGE2

98 12 cells or PC12 cells that are deficient in cyclic AMP-dependent protein kinase (PKA), two observati

99 putative residue for phosphorylation by the cyclic AMP-dependent protein kinase (PKA), we examined t

100 onstitutive) lipolysis and as an enhancer of cyclic AMP-dependent protein kinase (PKA)-stimulated lip

101 and is subject to negative regulation by the cyclic AMP-dependent protein kinase (PKA).

102 al bundle upon phosphorylation by the enzyme cyclic AMP-dependent protein kinase (PKA).

103 interaction between the catalytic subunit of cyclic AMP-dependent protein kinase (PKA-Calpha) and SAF

104 type Ialpha regulatory subunit (RIalpha) of cyclic AMP-dependent protein kinase (PKA; PRKAR1A) lead

105 delta, contains sites for phosphorylation by cyclic-AMP dependent protein kinase (PKA) but not Cdc2 k

106 ieved by spatial and temporal enhancement of cyclic-AMP-dependent protein kinase (PKA) activity speci

107 The cross-modulation of glycine responses by cyclic-AMP-dependent protein kinase (PKA) and protein ki

108 u with 441 amino acids was phosphorylated by cyclic-AMP-dependent protein kinase (PKA) or glycogen sy

109 It encodes a protein with 23 predicted cyclic-AMP-dependent protein kinase (PKA) phosphorylatio

110 in naive synapses dephosphorylates the major cyclic-AMP-dependent protein kinase (PKA) site, whereas

111 tor are mediated through Gs proteins and the cyclic-AMP-dependent protein kinase (PKA) system, beta-a

112 The results also suggest that cyclic AMP-dependent protein kinase plays a key role in

113 e-anchoring protein (AKAP) that recruits the cyclic AMP-dependent protein kinase (protein kinase A (P

114 KACA, which encodes the catalytic subunit of cyclic AMP-dependent protein kinase (protein kinase A [P

115 We further show that the cyclic AMP-dependent protein kinase (protein kinase A [P

116 We also found that cyclic AMP-dependent protein kinase (protein kinase A) r

117 Transfection with a plasmid encoding the cyclic AMP-dependent protein kinase (protein kinase A; P

118 ding on transcription, protein synthesis and cyclic-AMP-dependent protein kinase (protein kinase A, o

119 ding in an orientation similar to binding of cyclic AMP-dependent protein kinase rather than that of

120 ain of the type Ialpha regulatory subunit of cyclic AMP-dependent protein kinase (RI) with the tyrosi

121 Activation of cyclic AMP-dependent protein kinase signaling also modul

122 Conversely, cyclic AMP-dependent protein kinase signaling has a repr

123 s as a phosphoprotein and that activation of cyclic AMP-dependent protein kinase signaling modulates

124 esults define the species-specific impact of cyclic AMP-dependent protein kinase signaling on pregnan

125 We show here that activation of the cyclic AMP-dependent protein kinase signaling pathway sy

126 Cyclic AMP-dependent protein kinase specifically phospho

127 orylated histone H1 and a peptide encoding a cyclic AMP-dependent protein kinase substrate.

128 In the structure of cyclic AMP-dependent protein kinase, the catalytic loop

129 owever, the effect of FGF is not mediated by cyclic AMP-dependent protein kinase, TPA-sensitive isofo

130 Deuteration of amide protons on cyclic AMP-dependent protein kinase was measured after s

131 ATP-phosphates and CDK2, binding studies of cyclic AMP-dependent protein kinase with ATP analogues s

132 lthough the interaction of serine/threonine, cyclic AMP-dependent protein kinase with protein kinase