ライフサイエンスコーパス: cyclic AMP

1 ium tuberculosis (Mtb) uses a complex 3', 5'-cyclic AMP (cAMP) signaling network to sense and respond

2 ADPKD pathology is elevated levels of 3', 5'-cyclic AMP (cAMP).

3 hat elevate the intracellular level of 3',5'-cyclic AMP (cAMP), indicating that MeCP2 may function as

4 A cyclic AMP receptor protein (CRP)-binding site (viz.

5 We show that a SP binding site and a cyclic AMP response element (CRE) in the ITGB8 core prom

6 and heart failure based on its activity as a cyclic AMP booster.

7 As a cyclic AMP effector, CRTC1 mediates anti-steatotic effec

8 2DL4 transcription, with contributions by a cyclic AMP response element (CRE) and initiator elements

9 a CCAAT enhancer binding (C/EBP) element, a cyclic AMP response element (CRE) and two activator prot

10 MC1R encodes a cyclic AMP-stimulating G-protein-coupled receptor that c

11 A gene encoding a cyclic AMP (cAMP) receptor protein (CRP) was identified

12 -cell factor/beta-catenin transcription in a cyclic AMP response-element binding protein binding prot

13 ontrolled by glycogen synthase kinase 3 in a cyclic AMP-protein kinase A-dependent manner.

14 d functional measurements of production of a cyclic AMP response element upstream of a secreted place

15 by various mycobacterial species produces a cyclic AMP burst within macrophages that influences cell

16 ements within the -4.5 kb promoter region (a cyclic AMP response and a downstream NF-E2/AP-1 element,

17 n, and facilitates lumen expansion through a cyclic AMP/protein kinase A (cAMP/PKA)-dependent pathway

18 itates autophagy through direct binding to a cyclic AMP response element binding site in the LC3B pro

19 Using a cyclic AMP (cAMP) assay and a Western blot for phosphory

20 timulate Na-dependent fluid absorption via a cyclic AMP-independent process involving apical membrane

21 These studies revealed a cyclic-AMP-dependent melanocytic signalling network not

22 intramitochondrial CO2-adenylyl cyclase (AC)-cyclic AMP (cAMP)-protein kinase A (PKA) pathway regulat

23 Accordingly, cyclic AMP/PKA signaling switches the fate of Nur77 from

24 -transcriptional hyperpolarization-activated cyclic AMP-gated channel (HCN1/2) up-regulation may unde

25 bodies, they inhibited G protein activation (cyclic AMP accumulation), G protein-coupled receptor kin

26 effective substrate for catalytically active cyclic AMP-dependent protein kinase in vitro.

27 oDCs, signaling through TLR8 in an adenosine/cyclic AMP-refractory manner.

28 Four of the selected 10 candidates (AIF, cyclic AMP-responsive element binding protein, ephrin ty

29 B-ZIP [CCAAT/enhancer-binding protein alpha, cyclic AMP-response element-binding protein (CREB), and

30 ion channels and mobilization of Ca(2+) and cyclic AMP (cAMP) signalling pathways.

31 e rod homeobox, orthodenticle homolog 2, and cyclic AMP response element-binding protein to predicted

32 regulated kinase 1/2 (ERK1/2) activation and cyclic AMP (cAMP) inhibition.

33 by beta-adrenergic receptors, cyclic AMP and cyclic AMP-dependent protein kinase.

34 ptosis signal-regulating kinase 1 (ASK1) and cyclic AMP (cAMP) response element-binding protein (CREB

35 ate feedforward calcium-protein kinase C and cyclic AMP-protein kinase A signaling, which open potass

36 EP-PTS are mediated by adenylate cyclase and cyclic AMP (cAMP) levels.

37 ule), possibly through adenylate cyclase and cyclic AMP signaling and a cytoplasmic heat-shock protei

38 The dopamine and cyclic AMP-regulated phosphoprotein of MR 32000 (DARPP-3

39 release, nucleoplasmic Ca(2+) elevation and cyclic AMP response element binding protein (CREB)-depen

40 tory showed significant decreases in ERK and cyclic AMP response element binding protein (CREB), but

41 growth factor 1 (IGF1), glucocorticoid, and cyclic AMP (cAMP)] triggers DNA replication and reentry

42 fluorescent biosensors for cyclic di-GMP and cyclic AMP-GMP by fusing the Spinach aptamer to variants

43 g extracellular signal-regulated kinases and cyclic AMP response element-binding protein.

44 terol loading, liver X receptor ligands, and cyclic AMP, and N-glycosylated SMPDL3A protein is detect

45 of the leucine-responsive protein (Lrp) and cyclic AMP (cAMP) receptor protein (CRP) in the transcri

46 and lsrRK operons are regulated by LsrR and cyclic AMP receptor protein (CRP) and that proper regula

47 utput and genetic program, including Ras and cyclic AMP response element-binding protein pathways and

48 astoma cells includes activation of RhoA and cyclic AMP response element-binding protein (CREB).

49 receptor EP2- and EP4-mediated signaling and cyclic AMP pathways to up-regulate IL-23 and IL-1 recept

50 r cyclic dinucleotides, such as c-di-GMP and cyclic-AMP-GMP, via interactions with both the backbone

51 8 mitogen-activated protein (MAP) kinase and cyclic-AMP-response element binding protein (CREB) activ

52 nists on IgE-dependent histamine release and cyclic-AMP generation in mast cells were determined.

53 VIPR2 transcription and cyclic-AMP signalling were significantly increased in cu

54 rane receptors and second messengers such as cyclic AMP.

55 ription factor 3 (ATF3), a member of the ATF/cyclic AMP response element-binding (ATF/CREB) family of

56 ) regulation of neuronal function, with both cyclic AMP (cAMP)- and RAS-dependent mechanisms describe

57 essed by means of preincubation with 8-bromo-cyclic AMP and forskolin.

58 own adipocytes by beta-AR agonism or 8-bromo-cyclic AMP increased the expression of PGC1alpha, PDK4,

59 lase in vitro, and the cAMP analogue 8-bromo-cyclic AMP partially rescued the circadian phenotype in

60 ereas the latter was also induced by 8-bromo-cyclic AMP.

61 h a membrane-permeant cAMP analogue (8-bromo-cyclic AMP; 8-Br-cAMP), stimulation of adenylate cyclase

62 t the exchange protein directly activated by cyclic AMP (Epac) increases melanoma cell migration via

63 el Galpha/cAMP/exchange protein activated by cyclic AMP (Epac)-dependent signaling pathway and requir

64 ch as exchange protein directly activated by cyclic AMP (EPAC).

65 of an exchange protein directly activated by cyclic AMP 1 (cAMP-1; Epac-1) on MERS-CoV replication.

66 acs (exchange proteins directly activated by cyclic AMP [cAMP]) act as downstream effectors of cAMP a

67 pac1 (exchange protein directly activated by cyclic AMP [cAMP]) couples intracellular cAMP to the act

68 P and exchange protein directly activated by cyclic AMP was required for the histamine effect on LPS-

69 suggests that Vfr activity is controlled by cyclic AMP (cAMP), it has been hypothesized that the put

70 urrent prostate cancer, which is enhanced by cyclic AMP signaling, increases AR-dependent growth of p

71 adipocytes stimulates energy expenditure by cyclic AMP (cAMP)-dependent increases in lipolysis and f

72 LuxR is regulated in response to glucose by cyclic AMP (cAMP) receptor protein (CRP).

73 fetal lung (HFL) is dramatically induced by cyclic AMP (cAMP).

74 rotein E (HYPE) and filamentation-induced by cyclic AMP (FIC)-1, respectively-in Saccharomyces cerevi

75 Filamentation induced by cyclic AMP (FIC)-domain enzymes catalyze adenylylation o

76 proteins with FIC (filamentation induced by cyclic AMP) domains use a conserved enzymatic machinery

77 Protein phosphorylation by cyclic AMP-dependent protein kinase (PKA) underlies key

78 ges shift when h-channels are potentiated by cyclic AMP.

79 e regulated at the level of transcription by cyclic AMP (cAMP) receptor protein (CRP).

80 , whereas stabilization of RP transcripts by cyclic AMP did not affect translation repression, sugges

81 , the toxic moiety which increases host cell cyclic AMP (cAMP).

82 In cardiomyocytes and smooth muscle cells, cyclic AMP (cAMP) and subsequent calcium (Ca(2+)) fluxes

83 intracellular Ca(2+) and decreased cellular cyclic AMP (cAMP).

84 receptors contribute to the overall cellular cyclic AMP response within several minutes after agonist

85 at impairs host defenses by raising cellular cyclic AMP (cAMP) levels.

86 er function was independent of the classical cyclic AMP/protein kinase A signaling machinery, endothe

87 action with the transcriptional coactivators cyclic-AMP response element-binding protein (CREB)-bindi

88 on factor homologous to the Escherichia coli cyclic AMP (cAMP) receptor protein (CRP), regulates many

89 tein interactions using the Escherichia coli cyclic AMP receptor protein (CRP).

90 Escherichia coli cyclic-AMP receptor protein (CRP) represents one of the

91 R and two sequences resembling the consensus cyclic AMP receptor protein (CRP) binding site were iden

92 n a common pathway with the widely conserved cyclic-AMP receptor protein that regulates protease prod

93 Conversely, cyclic AMP-dependent protein kinase signaling has a repr

94 affected the recruitment of the coregulators cyclic-AMP response element-binding protein-binding prot

95 CREB (cyclic AMP response element-binding protein) is a stimul

96 (activating transcription factor) and CREB (cyclic AMP response element-binding).

97 MIE enhancer binding sites for either CREB (cyclic AMP [cAMP] response element [CRE]) or NF-kappaB (

98 The transcriptional factor CREB1 (cyclic AMP [cAMP]-responsive element-binding protein 1)

99 , possibly through the activation of Creb3l3/cyclic AMP-responsive element-binding protein.

100 m that requires cAMP receptor protein (CRP), cyclic AMP (cAMP) and a CRP-S site in the sxy promoter.

101 In NC cultures, cyclic AMP (cAMP) induces melanocyte differentiation whi

102 in human breast cancer cell lines decreases cyclic AMP production, induces apoptosis, and blocks col

103 deletion of either cya or crp, demonstrating cyclic AMP (cAMP)-dependent activation of the P fimbrial

104 Dibutyryl cyclic AMP decreased NHERF1 and NHERF2 and increased SR-

105 cell permeable cyclic AMP analogue dibutyryl cyclic AMP (dbcAMP) resulted in a strong upregulation of

106 derived neurotropic factor (BDNF), dibutyryl cyclic AMP, and retinoic acid.

107 tner that directly couples the Dictyostelium cyclic AMP GPCR to Rap1.

108 enriched in the hippocampus that breaks down cyclic AMP and cyclic GMP.

109 anine or 8-bromo-cyclic GMP activates either cyclic AMP-dependent or cyclic GMP-dependent protein kin

110 For example, elevated cyclic-AMP signalling reduces persistent firing by openi

111 t missense mutations in PDE4D, which encodes cyclic AMP (cAMP)-specific phosphodiesterase 4D, were fo

112 Moreover, miR-132 overexpression enhanced cyclic AMP-response element-binding protein (CREB) phosp

113 Here we show that Epac1 (cyclic AMP sensor) potentiation of Piezo2-mediated mecha

114 orylates the downstream transcription factor cyclic AMP response element binding protein (CREB), whic

115 The transcription factor cyclic AMP-response element-binding protein 1 (CREB1) co

116 nd protein kinase A and transcription factor cyclic AMP-responsive element binding protein, regulator

117 Here we report that the transcription factor cyclic AMP-responsive element-binding protein H (CREB-H,

118 d by the liver-enriched transcription factor cyclic-AMP-responsive-element-binding protein H (CREBH)

119 in (CysLT(1)) expression using calcium flux, cyclic AMP, and chemotaxis assays.

120 ed on G-protein-coupled receptors (GPCR) for cyclic AMP (cAMP), a transduction step based on a hetero

121 re we uncover a novel regulatory pathway for cyclic AMP (cAMP) signaling by the phosphatase calcineur

122 nd contains a conserved recognition site for cyclic AMP-dependent protein kinase (PKA), corresponding

123 A synthase for cyclic AMP-GMP (cAG, also referenced as 3'-5', 3'-5' cGA

124 vation of class I (lac) and class II (galP1) cyclic AMP receptor protein-dependent promoters.

125 helix DNA-binding protein like its homologue cyclic AMP receptor protein (CRP).

126 ecently demonstrated that inhibition of host cyclic AMP-dependent protein kinase (PKA) activity negat

127 synthesizes a previously undescribed hybrid cyclic AMP-GMP molecule.

128 neutralized EF, as assayed by an increase in cyclic AMP (cAMP) production by Chinese hamster ovary (C

129 x is activated in response to an increase in cyclic AMP (cAMP) signaling.

130 dopaminergic neurons generated increases in cyclic AMP (cAMP) across multiple spatial regions in the

131 arly equipotent with their parent peptide in cyclic AMP activation assays, but the GLP-1 thiopeptides

132 Activation of the A2b receptor results in cyclic AMP-dependent activation of the cystic fibrosis t

133 d metabolomics reveals concomitant shifts in cyclic AMP and fucose metabolism consistent with photota

134 s steroidogenesis largely through a surge in cyclic AMP (cAMP).

135 Notably, deficits in cyclic-AMP response element-binding protein signaling we

136 ampal astrocytes induces a large increase in cyclic-AMP (cAMP) accumulation and release of adenosine.

137 Signal transduction studies included cyclic AMP and Ca(2+) mobilization assays.

138 y involving intracellular elements including cyclic AMP (cAMP).

139 des, and key regulatory molecules, including cyclic AMP (cAMP) receptor protein (CRP) and c-di-GMP, w

140 intracellular calcium (Ca(2+)) or increased cyclic AMP (cAMP), and subsequent protein kinase A activ

141 P2 agonists, but not EP4 agonists, increased cyclic-AMP levels in mast cells.

142 Drug combinations induce cyclic AMP (cAMP) accumulation and up-regulate PDE4B.

143 anscriptional level, PSEN1/2 removal induced cyclic AMP response element-binding protein (CREB)/CREB-

144 2 stimulated the expression of the inducible cyclic AMP early repressor, which appears to directly in

145 Adenylyl cyclase (AC) converts ATP into cyclic AMP (cAMP), an important second messenger in cell

146 inding protein) expression and intracellular cyclic AMP (cAMP), which correlates with attenuated CREB

147 ates in parallel two different intracellular cyclic AMP-dependent signaling branches mediated by prot

148 y and associated with elevated intracellular cyclic AMP (cAMP) and reduced plasma membrane localizati

149 require a receptor to generate intracellular cyclic AMP (cAMP) in a broad range of cell types.

150 associated with an increase in intracellular cyclic AMP (cAMP) and protein-kinase-A activity.

151 denylate cyclase, decreases in intracellular cyclic AMP (cAMP) levels and inhibition of protein kinas

152 nied by a >50-fold increase in intracellular cyclic AMP and a >4-fold increase in the phosphorylation

153 cyclases (ACs), which increase intracellular cyclic AMP (cAMP) levels in the exocrine pancreas.

154 nhancing effects via increased intracellular cyclic AMP (cAMP) signaling in the brain.

155 Ang II-induced intracellular cyclic AMP accumulation precedes CREB phosphorylation an

156 sodilator-induced elevation of intracellular cyclic AMP (cAMP) is a central mechanism governing arter

157 ith ST and their expression of intracellular cyclic AMP (cAMP) when treated with LT.

158 overcome through elevation of intracellular cyclic AMP (cAMP), as occurs with conditioning lesions o

159 ing supraphysiologic levels of intracellular cyclic AMP (cAMP).

160 e by modulating the amounts of intracellular cyclic AMP (cAMP).

161 In human MPhi, RvD2-stimulated intracellular cyclic AMP was dependent on GPR18.

162 duction in dendritic cells via intracellular cyclic AMP.

163 When intracellular cyclic AMP (cAMP) levels rise, GluA2/3 channels shift to

164 bitory cyclic nucleotide signaling involving cyclic AMP-dependent protein kinase A (PKA) and cyclic G

165 nger inhibited by myelin, and this effect is cyclic AMP (cAMP)- and transcription-dependent.

166 sence of admixed B subunit, it displayed low cyclic AMP (cAMP) induction and no enterotoxicity.

167 ity resulted from reduced G-protein-mediated cyclic AMP (cAMP) signaling.

168 aling via the intracellular second messenger cyclic AMP (cAMP) has long been implicated in the repres

169 In many bacteria, the second messenger cyclic AMP (cAMP) interacts with the transcription facto

170 The prototypic second messenger cyclic AMP (cAMP) is essential for controlling cellular

171 RATIONALE: Although the second messenger cyclic AMP (cAMP) is physiologically beneficial in the h

172 adation of the prolipolytic second messenger cyclic AMP (cAMP).

173 ar concentrations of the secondary messenger cyclic AMP, thereby impairing or activating host cell fu

174 ynthesizes the asymmetric signaling molecule cyclic AMP-GMP (cAG or 3', 3'-cGAMP).

175 Following cAMP elevation, neuritogenic cyclic AMP sensor/Rapgef2 is activated for signaling to

176 sors protein kinase A, Epac, or neuritogenic cyclic AMP sensor/Rapgef2 but, rather, depend on ERK and

177 such as gradual hypoxia, nitric oxide (NO), cyclic AMP and in vivo conditions, and measured transcri

178 a-MSH increased intracellular Ca(2+) but not cyclic AMP levels.

179 calcium flux and ERK phosphorylation but not cyclic AMP production or CREB phosphorylation.

180 Activation of cyclic AMP-dependent protein kinase signaling also modul

181 s as a phosphoprotein and that activation of cyclic AMP-dependent protein kinase signaling modulates

182 Inhibitors and activators of cyclic AMP (cAMP)-dependent pathways were used to assess

183 rehalose or glycerol, but not by addition of cyclic AMP.

184 eassembled MHC-II enhanceosome consisting of cyclic AMP response element-binding protein (CREB) and n

185 medium spiny neurons and in dysregulation of cyclic AMP signaling, cell death and protocadherin genes

186 activation of adenylyl cyclase, elevation of cyclic AMP levels, and protein kinase A (PKA) activation

187 en combined with neurotrophins, elevation of cyclic AMP levels, olfactory ensheathing cells, a steroi

188 eptor and provide a molecular explanation of cyclic AMP-dependent protein kinase-mediated repression

189 Both over expression of cyclic AMP response element binding protein (CREB) in th

190 ochemical or real time FRET-based imaging of cyclic AMP revealed that deletion of AKAP5 sensitized th

191 esults define the species-specific impact of cyclic AMP-dependent protein kinase signaling on pregnan

192 toxic effect of LT resulting in increases of cyclic AMP (cAMP) and disturbance of cellular metabolic

193 Inhibition of cyclic AMP (cAMP)-specific phosphodiesterase 4 (PDE4) ha

194 onical LT pathway, because the inhibition of cyclic AMP response element (CRE)-binding protein (CREB)

195 ond, PB25 likely possesses a higher level of cyclic AMP (cAMP) than JM101.

196 nylate cyclase that generates high levels of cyclic AMP (cAMP), causing alterations in multiple host

197 inhibit adenylate cyclase, reduce levels of cyclic AMP and protein kinase A (PKA) activity, abrogate

198 whose activity depends on cellular levels of cyclic AMP).

199 Activating Peptide (PACAP) impacts levels of cyclic AMP, a key second messenger available in brain ce

200 protein kinase A-mediated phosphorylation of cyclic AMP response element binding protein (CREB).

201 A subunit capable of inducing production of cyclic AMP and not on the B subunit.

202 cyaA, that is defective in the production of cyclic AMP, which extends lifespan and enhances dauer fo

203 nylate cyclase 5 catalyzes the production of cyclic AMP, which is a second messenger molecule involve

204 y were used to confirm in vivo production of cyclic AMP-GMP by the enzyme DncV.

205 reviously, we demonstrated that silencing of cyclic AMP (cAMP) response element binding protein 3-lik

206 KACA, which encodes the catalytic subunit of cyclic AMP-dependent protein kinase (protein kinase A [P

207 ce lacking the RIIbeta regulatory subunit of cyclic AMP-dependent protein kinase A (PKA) display redu

208 SP family verprolin homologous/suppressor of cyclic AMP receptor) regulatory complex (W/SRC) is an ev

209 n ovariectomized rats via phosphorylation of cyclic-AMP response element binding protein, which requi

210 s with both positive and negative effects on cyclic AMP-protein kinase A signaling underlie much of t

211 se studies explore the effects of statins on cyclic AMP-modulated signaling pathways in vascular endo

212 iotic progression and decreased intra-oocyte cyclic AMP (cAMP) levels in perinatal ovaries.

213 ntal stages, chemotaxing to either folate or cyclic AMP and moving with both blebs and pseudopods or

214 atment of BeWo cells with the cell permeable cyclic AMP analogue dibutyryl cyclic AMP (dbcAMP) result

215 ceptor gamma coactivator 1alpha (PGC1alpha), cyclic AMP-responsive element binding protein binding pr

216 MP-dependent protein kinase A (PKA), phospho-cyclic AMP response-element binding protein (phospho-CRE

217 BDNF) induction and increased phosphorylated cyclic-AMP response-binding protein (pCREB) to CREB rati

218 gage the key regulator of skin pigmentation, cyclic AMP, showing a major difference compared with the

219 rotrophic factor (BDNF)/TrkB and presynaptic cyclic AMP (cAMP)/PKA signaling.

220 In addition to an expected primary cyclic AMP-binding site, a second ligand-binding site is

221 s, and functional assays that RGS17 promotes cyclic AMP (cAMP)-responsive element binding protein (CR

222 system, and the cyclic AMP receptor protein-cyclic AMP (CRP-cAMP) complex.

223 Tax binds the cyclin D1 promoter-proximal cyclic AMP response element (CRE) in the presence of pho

224 VASP bundles Rac1, Rac2, cyclic AMP-dependent, and cyclic GMP-dependent protein k

225 inoic acid receptor binding elements [RARE], cyclic AMP [cAMP] response elements [CRE], NF-kappaB bin

226 t is initiated by beta-adrenergic receptors, cyclic AMP and cyclic AMP-dependent protein kinase.

227 was initiated by beta-adrenergic receptors, cyclic AMP and protein kinase A as revealed by pharmacol

228 exhibit increased RAS activation and reduced cyclic AMP generation, there was a neurofibromin dose-de

229 hen cells re-orientate to a needle releasing cyclic-AMP, they stereotypically produce first microspik

230 ding was dependent on GTGAN6CCACC and showed cyclic AMP (cAMP) dependency.

231 Hundreds of hormones and ligands stimulate cyclic AMP (cAMP) signaling in different tissues through

232 Thus agonists that stimulate cyclic AMP production may cause relaxation with resultan

233 C5F2 stimulated cyclic AMP production in beta2AR-transfected CHO cells a

234 ing duct through adenylyl cyclase-stimulated cyclic AMP, which exists as multiple isoforms; the speci

235 wn to antagonize hepatic glucagon-stimulated cyclic AMP (cAMP) signalling independently of AMP-activa

236 induced by LKB1 inactivation and subsequent cyclic AMP-responsive element-binding protein (CREB)/CRE

237 esistance to bile, and ability to synthesize cyclic AMP-GMP.

238 control open field nor rotarod motor tests; cyclic AMP responses to stimulation of D1 receptors by d

239 uclei of H295R adrenocortical cells and that cyclic AMP (cAMP) signaling promotes nuclear sphingolipi

240 Previously we have demonstrated that cyclic AMP response element binding protein (CREB) is co

241 In this paper, we report that cyclic AMP (cAMP)-dependent protein kinase A (PKA) promo

242 Here we reported that cyclic AMP-responsive element-binding protein H (CREBH)

243 The cyclic AMP (cAMP) receptor protein (CRP) indirectly incr

244 The cyclic AMP (cAMP)-dependent catabolite repression effect

245 The cyclic AMP protein kinase A pathway governs numerous bio

246 The cyclic AMP response element binding protein (CREB) is a

247 The cyclic AMP response element-binding protein (CREB) initi

248 The cyclic AMP-induced increase in androgen-dependent and an

249 The cyclic AMP-responsive element binding- and NMDA-regulate

250 protein kinases, which in turn activated the cyclic AMP response element-binding protein and the micr

251 promotes axon regeneration by activating the cyclic AMP (cAMP) signalling pathway.

252 olvement of a PDE gene in TGCT, although the cyclic AMP signaling pathway has been investigated exten

253 r factor of activated T cells (NFAT) and the cyclic AMP (cAMP) response element (CRE) modulate KSHV-m

254 sive ArcA-ArcB two-component system, and the cyclic AMP receptor protein-cyclic AMP (CRP-cAMP) comple

255 essed by prostaglandin E(2) (PGE(2)) and the cyclic AMP-dependent protein kinase A (PKA).

256 of fad regulon genes, its modulation by the cyclic AMP (cAMP) receptor protein-cAMP complex (CRP-cAM

257 the canonical pH-sensing pathway and by the cyclic AMP (cAMP)/protein kinase A (PKA) pathway.

258 e propose reflects regulation of feaR by the cyclic AMP receptor protein (CRP) and the nitrogen assim

259 is subject to transcriptional control by the cyclic AMP receptor protein, riboswitch-mediated transcr

260 he trg promoter is activated directly by the cyclic AMP receptor protein.

261 SHIP1 can be phosphorylated by the cyclic AMP-dependent protein kinase (PKA), resulting in

262 dimerization and docking (D/D) domain of the cyclic AMP (cAMP)-dependent protein kinase.

263 altered expression of many components of the cyclic AMP and WNT signalling pathways.

264 Triggering of the cyclic AMP pathway increases gluconeogenic gene expressi

265 In thyroid FRTL-5 cells, activation of the cyclic AMP pathway increases the association of Nedd4 wi

266 are mediated, in part, by activation of the cyclic AMP response element binding protein (Creb) in th

267 c28, and Som1, a downstream regulator of the cyclic AMP-dependent Protein Kinase A pathway.

268 on GBSM, and this leads to activation of the cyclic AMP-PKA pathway, and ultimately the opening of K(

269 hese candidate genes, six are members of the cyclic AMP-protein kinase A pathway, an evolutionarily c

270 se miRNAs directly reduced expression of the cyclic AMP-responsive element-binding protein (CBP), whi

271 ts or transfected with caveolin-1 siRNA, the cyclic AMP response to the beta(3)-AR agonist CL316243 b

272 Here, we report that the cyclic AMP (cAMP) response of CRHR1 in physiologically r

273 Here, we report that the cyclic AMP/Vfr-dependent signaling (CVS) pathway is defe

274 tes target gene expression by binding to the cyclic AMP-response element as a homodimer or a heterodi

275 three transcription factors that bind to the cyclic AMP-responsive elements on the Mkp-1 promoter.

276 iration, Shewanella oneidensis MR-1 uses the cyclic AMP receptor protein (CRP) for this purpose.

277 oneidensis is a metal reducer that uses the cyclic AMP receptor protein, CRP, to regulate anaerobic

278 F-kappaB and factors that associate with the cyclic AMP-response element adjacent to the NF-kappaB si

279 as the retinoblastoma protein (pRb) and the cyclic-AMP response element binding binding protein (CBP

280 ave usually been attributed to action of the cyclic-AMP Response Element Binding Protein (CREB).

281 t amygdala neurons with higher levels of the cyclic-AMP-response-element-binding protein (CREB) are m

282 It appears that the cyclic-AMP-CRP regulatory system has been adapted to res

283 ts caused by plasma adenosine acting through cyclic AMP.

284 of differentiating brown adipocytes through cyclic AMP (cAMP)/protein kinase A (PKA)-mediated lipoly

285 H(2)R signaling through cyclic AMP and exchange protein directly activated by cy

286 t, like classical brown fat, they respond to cyclic AMP stimulation with high UCP1 expression and res

287 ental mammals changed the way it responds to cyclic AMP/protein kinase A (cAMP/PKA) signalling.

288 it did potentiate the secretory response to cyclic AMP agonists.

289 Blebbing cells are strongly chemotactic to cyclic-AMP, producing nearly all of their blebs up-gradi

290 tylation at CREB-target genes in response to cyclic-AMP, yet transcription was not uniformly inhibite

291 f the phosphodiesterase 4B (PDE4B) unleashes cyclic-AMP (cAMP) inhibitory effects toward the PI3K/AKT

292 us in vitro phosphoryl transfer assays using cyclic AMP-dependent protein kinase as a representative

293 nctional activity assays, performed by using cyclic AMP experiments, assessed that they behave as pot

294 s neurotransmitters, regulate PDAC cells via cyclic AMP (cAMP)-dependent signaling in vitro, that soc

295 criptionally upregulated by gonadotropin via cyclic AMP/androgen through androgen receptors (AR).

296 nes in response to histamine stimulation via cyclic AMP elevation.

297 While cyclic AMP (cAMP)-mediated signaling has been shown to b

298 factor POU1F1 to the GH promoter along with cyclic AMP (cAMP) response element binding protein (CREB

299 ry rat granulosa cells and MLTC-1 cells with cyclic AMP (cAMP) or in vivo treatment of rat adrenals w

300 -ZIP domain, APH-2, like HBZ, interacts with cyclic AMP response element binding protein (CREB) and d