ライフサイエンスコーパス: cyclization reaction

1 )-Ynamides are converted to oxazolones via a cyclization reaction.

2 zo[b][1,6]naphthyridones via a base-mediated cyclization reaction.

3 a sequential Suzuki-Miyaura coupling/Petasis cyclization reaction.

4 the activated triple bond competes with the cyclization reaction.

5 result is retention of configuration in the cyclization reaction.

6 se peptide synthesis chemistry and a rhenium cyclization reaction.

7 new example of a dynamic kinetic asymmetric cyclization reaction.

8 ting the folding of the substrate during the cyclization reaction.

9 etermined to be large enough to dominate the cyclization reaction.

10 imics of the tetrahedral intermediate in the cyclization reaction.

11 idine were also used for the tandem coupling-cyclization reaction.

12 ered pi-bonds undergo a related acid-induced cyclization reaction.

13 is region is important for the corresponding cyclization reaction.

14 etal ion" hybrid mechanism to facilitate the cyclization reaction.

15 used was found to affect the outcome of the cyclization reaction.

16 way for either C- or D-ring formation in the cyclization reaction.

17 ntibody 4C6 efficiently catalyzes a cationic cyclization reaction.

18 cantly alter the pK(a) of the intramolecular cyclization reaction.

19 model for pilin-precursor processing and the cyclization reaction.

20 ide and tetraketide intermediates during the cyclization reaction.

21 ormation of FAICAR with the highly favorable cyclization reaction.

22 c diphosphate ester function to initiate the cyclization reaction.

23 olefins could serve as intermediates of the cyclization reaction.

24 bridization during a single enzyme-catalyzed cyclization reaction.

25 dinated diyne for the further intramolecular cyclization reaction.

26 ngement and Zn-ene-allene (or Zn-yne-allene) cyclization reaction.

27 es was achieved through a sequential Ugi-4CR/cyclization reaction.

28 for the diphosphate anion coproduct in this cyclization reaction.

29 f formylation that is attended by an unusual cyclization reaction.

30 ts the first example of a light-controllable cyclization reaction.

31 , a tandem beta-fragmentation-intramolecular cyclization reaction.

32 MeHg(+) and hCy7 through a mercury-promoted cyclization reaction.

33 tiated) and class II (protonation-initiated) cyclization reactions.

34 monophosphine Au-catalyzed monoallylic diol cyclization reactions.

35 n reactivity in many gold(I)-catalyzed enyne cyclization reactions.

36 ticipation of the lone pair electrons in the cyclization reactions.

37 fferent 1,5-epoxyalcohols and initiate their cyclization reactions.

38 te a new mechanism for racemization in Prins cyclization reactions.

39 l radicals are trapped by subsequent radical cyclization reactions.

40 is sequence, featuring two resin-bound macro-cyclization reactions.

41 catalyzes the oxidative deamination and the cyclization reactions.

42 dimerization observed in the intramolecular cyclization reactions.

43 important for controlling the hydrolysis and cyclization reactions.

44 n many important chemical processes, such as cyclization reactions.

45 l as intermediates of prototypical 1,6-enyne cyclization reactions.

46 s/intermediates in asymmetric intramolecular cyclization reactions.

47 carbinyl fragmentation avoided the secondary cyclization reaction (25 or 43 --> 26 or 44), whereas us

48 The enzyme catalyzing the cyclization reaction, abietadiene synthase, was purified

49 ated enyne-allene 21 followed by a C(2)-C(6) cyclization reaction and an intramolecular radical-radic

50 The examination of the reductive cyclization reaction and optimization of conditions is d

51 reaction to probe the mechanism of the Prins cyclization reaction and the subsequent nucleophilic cap

52 The relative rates of both the HDDA cyclization reactions and the simple DA cycloadditions w

53 s of this work was the use of olefinic-ester cyclization reactions and the utilization of glycal epox

54 a derailment of the natural anti-Markovnikov cyclization reaction, and not simply the consequence of

55 The pathways for C-Cl bond cleavage and cyclization reactions are discussed.

56 f several possibilities for the key bridging cyclization reaction, are described.

57 ia a highly diastereoselective N-acyliminium cyclization reaction as a key synthetic step.

58 The use of a cationic cyclization reaction as a probe of the glycosylation mec

59 olia to elucidate the stereochemistry of the cyclization reaction at these positions.

60 in competition with radical ring opening and cyclization reactions at reduced temperatures.

61 rresponding cycloaddition product makes this cyclization reaction attractive for a synthetic route to

62 effects disfavor the thermal C1-C6 diradical cyclization reaction (Bergman) and electronic effects fa

63 Compound 1 is prepared via a tripod-tripod cyclization reaction between 1,3,5-tris-bromomethyl-benz

64 eoside was accomplished by an intramolecular cyclization reaction between a radical at the 2'-positio

65 An anodic cyclization reaction between an enol ether radical catio

66 demonstrated employing a Pictet-Spengler bis-cyclization reaction between commercially available (R)-

67 F, II.Rh, effectively catalyzed Pauson-Khand cyclization reactions between 1,6-enynes and carbon mono

68 During investigations of cyclization reactions between chiral allylsilanes and N-

69 g and sulphur transfer steps are used in the cyclization reaction, but a 5'- H -phosphonate intermedi

70 r groups at C3 in radicals 8b slow the 3-exo cyclization reaction by a factor of 50.

71 enerate dehydrated peptides for study of the cyclization reaction by wild type LctM.

72 four-step sequence featuring a condensation/cyclization reaction cascade between 4-(2-aminophenyl)py

73 ich serves as the substrate for a subsequent cyclization reaction catalyzed by a terpenoid cyclase, m

74 -linalyl diphosphate and preceding the final cyclization reaction catalyzed by the monoterpene syntha

75 suicide inhibition, cyclization, and reverse cyclization reactions catalyzed by a group I intron from

76 he asymmetric intramolecular indium-mediated cyclization reaction delivers chromanes with excellent d

77 A Pd(II)-catalyzed C-H activation/C-O cyclization reaction directed by a proximate hydroxyl gr

78 hydrations of Ser and Thr residues and three cyclization reactions during the biosynthesis of the cyt

79 nyl N-arylsulfonamides undergo the oxidative cyclization reaction efficiently.

80 In the mannose series the cyclization reaction employed as clock results in the fo

81 the products obtained have revealed that the cyclization reactions follow an initial 6-endo-dig proce

82 enantioselective hydroboration-homologation-cyclization reaction followed by a hydrolysis-lactonizat

83 ndem cationic aza-Cope rearrangement/Mannich cyclization reaction for accessing the unprecedented bri

84 We report herein a reversible ring-opening-cyclization reaction for some of these spirooxindoles, w

85 The approach is based on a SmI(2)-mediated cyclization reaction for the construction of the oxacycl

86 e particularly interested in the use of this cyclization reaction for the synthesis of 6-azabicyclo[3

87 istry to the commonly employed electrophilic cyclization reaction for the synthesis of benzo[b]thioph

88 The DFT calculation of the iodine-mediated cyclization reactions for molecules containing methoxy,

89 The utility of oxidative cyclization reactions for the construction of tetrahydro

90 ication of thiyl-radical-mediated 5-exo-trig cyclization reactions for the preparation of a series of

91 ay crystal structures shows clearly that the cyclization reaction forces the two naphthyl rings into

92 by SmI2 results in an instantaneous [2 + 3] cyclization reaction, forming a bridged seven-membered r

93 ared to identify relevant amino acids of the cyclization reaction from alpha-terpineol to 1,8-cineole

94 ts efficient and stereoselective dehydrative cyclization reactions from monoallylic diols, with stere

95 to catalyze highly enantioselective Nazarov cyclization reactions, giving rise to cyclopentenoids in

96 aining pincer ligand to Pt catalyzed cascade cyclization reactions has allowed for the catalytic, dia

97 ergent hydroimination and iminohydroxylation cyclization reactions has been accomplished through the

98 unctional groups toward alkyne electrophilic cyclization reactions has been studied.

99 These cyclization reactions have been developed experimentally

100 Several formal heteroborylative cyclization reactions have been recently reported, but l

101 Wacker-type oxidative cyclization reactions have been the subject of extensive

102 iates, also referred to as N-acyliminium ion cyclization reactions, have been employed for the constr

103 ut the increase of the quantum yields of the cyclization reaction in a nonpolar hexane is observed on

104 om M. tuberculosis that catalyzes an unusual cyclization reaction in converting the known M. tubercul

105 alyzes a highly stereoselective chlorination-cyclization reaction in napyradiomycin antibiotic biosyn

106 phosphorus hydride mediated radical addition/cyclization reaction in the key step.

107 zes two sequential, mechanistically distinct cyclization reactions in the formation of a mixture of a

108 The complex oxidative cyclization reaction involved in the biosynthesis of the

109 The cyclization reaction involves addition of a rhodium-stab

110 arbonyldiimidazole-mediated one-pot/two-step cyclization reaction involving amino acid unsymmetrical

111 or constructing metallabenzenes has emerged, cyclization reactions involving metal-thiocarbonyl, meta

112 ies grandis), and the olefin product of this cyclization reaction is considered to be the precursor i

113 sm, in which a thermodynamically unfavorable cyclization reaction is coupled to an electronic conjuga

114 The first cyclization reaction is initiated by protonation of the

115 e stereoselective nature in the C-N coupling cyclization reaction is interpreted in terms of minimiza

116 shortcoming is particularly costly when the cyclization reaction is performed after a long sequence

117 ectivity for the dimeric products 6 in these cyclization reactions is discussed.

118 ansient carbocation intermediates in terpene cyclization reactions is generally under kinetic rather

119 e substrate, which is the nucleophile in the cyclization reaction, is replaced with a hydroxyl group

120 During investigations of the radical cyclization reactions, it was discovered that excess tet

121 An intramolecular cyclization reaction leading to the loss of the C-X chai

122 toxy)hexanes have been synthesized and their cyclization reactions leading to di- and trisubstituted

123 iterpenoid oxidation activities, including a cyclization reaction, leading to a triterpenoid lactone.

124 ormation of amide bonds and their effects on cyclization reactions led us to alkylate the amide bond.

125 The cyclization reaction mechanism and the enantiomeric comp

126 By exploiting the ring-opening-cyclization reaction mechanism, we have designed and syn

127 thylhex-4-ene-1-thiol via (3,5)-thionium-ene cyclization reaction mediated by boron trifluoride ether

128 ynthesized from thioacrylates via thia-Prins cyclization reaction mediated by trimethylsilyltrifluoro

129 wo diastereochemically complementary radical cyclization reactions mediated by Ti(III) and Mn(III), r

130 as sufficient to "short circuit" the complex cyclization reaction normally catalyzed by ent-kaurene s

131 n the presence of oxygen, a radical addition/cyclization reaction occurred which resulted in the form

132 these alcohols to thionyl chloride, cascade cyclization reactions occurred to furnish polycyclic com

133 oacetonitrile, a subsequent condensation and cyclization reaction occurres to produced 4-amino-3,7-di

134 c phosphonamides have been synthesized via a cyclization reaction of (S,S)-aminobenzylnaphthols with

135 A tandem deprotection-cyclization reaction of 1,1-diacylcyclopropanes is descr

136 lightly more endothermic than the comparable cyclization reaction of 1b to 2b.

137 nium acetate assisted gold-catalyzed cascade cyclization reaction of 2-alkynylarylketones is describe

138 ified isoflavonoids 1-11 are proposed, and a cyclization reaction of 9 was conducted to support one o

139 esized by lanosterol synthase (LSS) in a key cyclization reaction of a cholesterol synthesis pathway.

140 ss a pyran ring formed through a spontaneous cyclization reaction of a dithiolene side-chain hydroxyl

141 The cyclization reaction of an epoxyalcohol is catalyzed by

142 A Sc(OTf)3-catalyzed three-component cyclization reaction of arylamines, beta,gamma-unsaturat

143 The halogen-mediated cyclization reaction of aryldiynes to produce halogenate

144 beta-carbon atom by a Mannich-type addition/cyclization reaction of isocyanoacetate pronucleophiles

145 an operationally simple, palladium-catalyzed cyclization reaction of N-aryl imines, affording indoles

146 using the same protocol, we carried out the cyclization reaction of relevant molecules, such as lapa

147 FP) is triggered by a spontaneous main chain cyclization reaction of residues 65-67.

148 rs, and it relies on the fourfold oligomeric cyclization reaction of resorcinol with 2,3-dihydrofuran

149 nd high-yielding indium trichloride mediated cyclization reaction of silylated homoallylic alcohols,

150 lkyne 6, and the intramolecular Michael-type cyclization reaction of the phenolic naphthoquinone 20.

151 A cationic cyclization reaction of the readily available 2-(2-(1H-i

152 The efficiency of the redox-mediated Bergman cyclization reaction of this stable Pt(0) metalloenediyn

153 An efficient 1,4-hydrovinylative cyclization reaction of triynes and tetraynes catalyzed

154 A catalytic asymmetric aldol addition/cyclization reaction of unactivated ketones with isocyan

155 nism of the Dess-Martin periodinane-mediated cyclization reaction of unsaturated anilides discovered

156 ngle-site solid catalysts for the asymmetric cyclization reactions of 1,6-enynes.

157 Novel molecular iodine catalyzed cyclization reactions of 2-amino anilines with aryl alky

158 ypothesis for the gem-dimethyl effect in the cyclization reactions of 2-chloroethoxide derivatives ha

159 demonstrate that at pH 7.5 the CHI-catalyzed cyclization reactions of 4,2',4',6'-tetrahydroxychalcone

160 e examined the spontaneous and CHI-catalyzed cyclization reactions of 4,2',4',6'-tetrahydroxychalcone

161 The intramolecular cyclization reactions of aziridines with pi-nucleophiles

162 The use of cascade cyclization reactions of benzannulated enyne-allenes as

163 In this review a collection of examples of cyclization reactions of bis(allenes) is presented as we

164 Parallel cyclization reactions of bromo ketone 10 with thioamides

165 ted lactams, prepared through group-transfer cyclization reactions of carbamoyl radicals, undergo a C

166 The ongoing controversy whether cyclization reactions of conjugated allenes or ketenes f

167 re is generated by periplasmic oxidation and cyclization reactions of d-tyrosine and l-diaminobutyric

168 eparation of chalcogenophene derivatives via cyclization reactions of diynols promoted by diorganyl d

169 Cyclization reactions of donor-acceptor (D-A) cyclopropa

170 The first cyclization reactions of enoldiazo compounds with nitros

171 transition metal-mediated cycloaddition and cyclization reactions of enyne and diyne substrates asse

172 his work, the mechanism of 10 representative cyclization reactions of hepta-1,2,4,6-tetraenes with di

173 This review aims to provide an overview of cyclization reactions of N-acyliminium ions derived from

174 Intramolecular endo-cyclization reactions of N-acyliminium ions have seen wi

175 We report herein copper(II)-catalyzed cyclization reactions of silyl enol ethers derived from

176 The 6-exo cyclization reactions of the enol ether radical cations

177 mics the second step of splicing and reverse cyclization reactions of the self-splicing intron from T

178 nificant structural similarity, catalyze the cyclization reactions of the universal alicyclic precurs

179 tate analogues, catalyze disfavored endo-tet cyclization reactions of trans-epoxy alcohols, in formal

180 Highly diastereoselective metalloamination/cyclization reactions of zinc(II) hydrazides obtained th

181 radical-forming C2-C6 cyclization (Schmittel cyclization) reaction of the chlorinated benzoenyne-alle

182 , was shown to be effective at promoting the cyclization reaction on a preparative scale.

183 The stereochemical outcome of cyclization reactions originating from the oxidation of

184 The cyclization reactions proceed via transition-state inter

185 The cyclization reaction proceeds with excellent diastereose

186 This cyclization reaction proceeds with the loss of only the

187 eropyrenes were formed after a 4-fold alkyne cyclization reaction promoted by triflic acid.

188 f the adenylate nucleophile required for the cyclization reaction provides slow hydrolysis as the onl

189 tial palladium-catalyzed alpha-arylation and cyclization reactions provides a general approach to an

190 The cyclization reactions require the electrogeneration of 1

191 The cyclization reaction requires an Asn at position P1 foll

192 t efficiency by means of a sortase-catalyzed cyclization reaction, requiring only minimal modificatio

193 landin H(2) requires two oxygenation and two cyclization reactions, resulting in the formation of fiv

194 ow how antibody catalysis can guide cationic cyclization reactions selectively to form products (in h

195 uctural basis for this coupled isomerization-cyclization reaction sequence can be inferred by homolog

196 followed by a hitherto unprecedented cascade cyclization reaction sequence comprising a Cu-catalyzed

197 chanistic studies suggest that the oxidative cyclization reaction sequence is initiated by an electro

198 alkoxyallylboration-hydroboration-iodination-cyclization reaction sequence.

199 hese synthons were examined in an ozonolysis/cyclization reaction sequence.

200 embered ring systems obtained by these novel cyclization reactions serve as useful and versatile inte

201 tional experiments are consistent with these cyclization reactions taking place by an anti-oxypallada

202 ta obtained by HPLC analysis support a rapid cyclization reaction that can be reversed upon acid dena

203 cross-coupling reaction and a photo-Nazarov cyclization reaction that deliver the complete nakiterpi

204 is a thermodynamically controlled asymmetric cyclization reaction that produces two new stereogenic c

205 The molecule is produced by an unusual cyclization reaction that yields mainly a product with C

206 -oxindoles undergo a reversible ring-opening-cyclization reaction that, from a single compound in pro

207 strong solvent polarity effect, whereas the cyclization reactions that gave distonic radical cation

208 re model, the LctM-catalyzed dehydration and cyclization reactions that occur in two distinct active

209 Terpene synthases often catalyze complex cyclization reactions that typically represent the commi

210 tituted peptides and suggest that during the cyclization reaction the peptide substrate is preorganiz

211 addition to the generality and scope of this cyclization reaction, this article describes a number of

212 ted that, after future implementation of the cyclization reactions, this framework can be used to ide

213 described, which involves an intramolecular cyclization reaction through a nucleophilic substitution

214 mploy an optimized first-order bioorthogonal cyclization reaction to control the self-assembly of a f

215 to which is an adventurous samarium-mediated cyclization reaction to establish the tricyclic core and

216 The experiments also revealed that the cyclization reaction to form 4-halo-thiophene derivative

217 or a two-step process involving a Schmittel cyclization reaction to form biradical 13 followed by an

218 follows: (a) a pinacol-terminated 1,6-enyne cyclization reaction to form the cis-hydrindanone core (

219 -allene 12, which then underwent a Schmittel cyclization reaction to generate the benzofulvene biradi

220 ient and diastereoselective radical addition/cyclization reaction to give trisubstituted piperidines

221 pliced precursor on chitin resin allowed the cyclization reaction to proceed in vitro.

222 ines participate in efficient intramolecular cyclization reactions to afford a variety of piperidine

223 of the subsequent dehydration and Paal-Knorr cyclization reactions to be measured.

224 ral alkynylindoles undergo gold(I)-catalyzed cyclization reactions to form a single isomer in each ca

225 donor (reverse addition), undergo efficient cyclization reactions to give N-heterocyclic furanosides

226 zation to give cyclic phosphonates and other cyclization reactions to give pi-rich P-heterocycles.

227 ndergo spontaneous intramolecular 5-exo-trig cyclization reactions to provide hydroxy-gamma-butyrolac

228 An oxidative cyclization reaction transforms nonemissive azoanilines

229 oxidation potential, contributes to a rapid cyclization reaction triggered by copper(II) ion in wate

230 Cyclization reactions triggered by the oxidation of a ke

231 s prepared and studied in the intramolecular cyclization reaction under acidic conditions in our seco

232 s effective in catalyzing the metalloradical cyclization reaction under neutral and mild conditions.

233 The 5-exo alkyl radical cyclization reaction under nonreductive Keck-allylation

234 nes 4, where R(3) is aryl, undergo 5-exo-dig cyclization reactions under relatively mild conditions (

235 nones 8, 17, and 18 undergo 2-fold reductive cyclization reactions upon exposure to hydrogen in the p

236 This work showcases a new catalytic cyclization reaction using a highly Lewis acidic borane

237 Enantioselective Michael addition-cyclization reactions using different alpha,beta-unsatur

238 demonstrate a one-pot, tandem dihalogenation-cyclization reaction, using the same catalytic system tw

239 anthanide-mediated, intramolecular amination/cyclization reaction was determined for the formation of

240 estigations, an interesting stereoconvergent cyclization reaction was discovered for the efficient as

241 The cyclization reaction was employed for a synthesis of the

242 A minor byproduct in the reductive cyclization reaction was identified that for the first t

243 ime, and amount of base on the efficiency of cyclization reaction was investigated.

244 An unexpected diastereoselective cyclization reaction was observed, leading preferentiall

245 The outcome of a new cyclization reaction was predicted by using these theore

246 The Rh(II)-catalyzed cyclization reaction was quite versatile with regard to

247 The utility of these cyclization reactions was illustrated with the synthesis

248 product of a Raney-cobalt mediated reductive cyclization reaction, was readily converted into the cis

249 The kinetic parameters of the cyclization reaction were also studied.

250 nalization, McMurry coupling, and finalising cyclization reactions were explored.

251 The 5-exo cyclization reactions were fast (k(c) > 2 x 10(5) s(-1))

252 The cyclization reactions were found to proceed in high yiel

253 ty of competitive pinacol rearrangements and cyclization reactions were overcome to develop a 7-step

254 ermediate, in contrast to other Au-catalyzed cyclization reactions where this intermediate severely r

255 anism is thought to be due to a head-to-tail cyclization reaction, where the N-terminal and C-termina

256 N-cinnamoyl-1-naphthylamines undergo a cyclization reaction with triflic acid to form 4-phenyl-

257 oach is exploited for multifold C-C coupling cyclization reactions with C-C cleavage using symmetrica

258 Two free-radical cyclization reactions with the radical at the chiral C4

259 dramatic impact on the ratio of exo- to endo-cyclization reactions, with bicyclo[4.1.0] intermediates

260 covered and used three times in Pauson-Khand cyclization reactions without deterioration of yields or