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1 iers such as SIGCAFKILGY(-cysteamine) [SIGC(-cysteamine)].
2 to produce pantothenic acid (vitamin B5) and cysteamine.
3 pionic acid, 4-pyridinylethanemercaptan, and cysteamine.
4 increased the production of hypotaurine from cysteamine.
6 -cysteine with isosteric substrate analogues cysteamine, 3-mercaptopropionic acid, and propane thiol
8 pered our understanding of the metabolism of cysteamine, a product of the constitutive degradation of
12 However, experimental studies with the thiol cysteamine and its disulfide cystamine have demonstrated
13 e or withanolide A, was highly reactive with cysteamine and rapidly succumbed to irreversible nucleop
14 therefore studied the actions of cystamine, cysteamine and several reference thiol agents as cytopro
15 ell-known radioprotective agents L-cysteine, cysteamine, and 2-[(aminopropyl)amino]ethanethiol (WR-10
18 t assay using 14C-(C-1)-labeled L-serine and cysteamine as substrates, counting the thialysine produc
20 ndings suggest that combination therapy with cysteamine bitartrate and N-acetylcysteine is associated
21 aimed to assess whether combination of oral cysteamine bitartrate and N-acetylcysteine is beneficial
22 olled trial to determine whether 52 weeks of cysteamine bitartrate delayed release (CBDR) reduces the
24 s, we evaluated the antifibrotic efficacy of cysteamine bitartrate, an antioxidant therapy for patien
25 the sensitive voltammetric determination of cysteamine (CA), nicotinamide adenine dinucleotide (NADH
26 such as acetone, acetaldehyde, isoprene, or cysteamine can be detected in the breath gas with SPI, R
32 Lipophilic thiols such as mercaptoethanol or cysteamine could partially reverse the CCl4-induced calc
36 yer principle by modifying Au electrode with cysteamine (Cys) and immobilization of ferrocene cored p
37 lized on the Au/SPE previously aminated with cysteamine (Cys) by self-assembling monolayer technique.
39 nic acid (cysteine without the amino group), cysteamine (cysteine without the carboxylic acid), or me
45 ly of enzymes includes cysteine dioxygenase, cysteamine dioxygenase, mercaptosuccinate dioxygenase, a
47 ned carbon chain and lacks a carboxyl group, cysteamine displays a catalytic efficiency (kcat/Km) wit
49 modified with a self-assembled monolayer of cysteamine followed by cross-linking with glutaraldehyde
51 to be ineffective at zinc ejection, although cysteamine formed a transient complex with the zinc fing
52 d that the steady state percentage yields of cysteamine from cystamine and pantethine during the tran
54 In the case of the bacterial member ELIC, a cysteamine-gated channel from Erwinia chrisanthemi, a st
55 abeled diketide-SNAC 2 and N-[1-(14)C-acetyl]cysteamine gave a k(exch) of 0.15 +/- 0.06 min(-)(1), wi
57 amine) specifically and efficiently leads to cysteamine (half-cystamine) modification of a single sit
58 ted the extracellular levels of free reduced cysteamine, homocysteine, and cysteine from OHSCs within
63 sed on layer-by-layer assembly was formed by cysteamine in combination with a fourth-generation poly(
64 relies upon the finding that hCBS will take cysteamine in place of L-homocysteine, thereby producing
66 of N-acetylating a model compound containing cysteamine in the presence of acetyl-CoA, consistent wit
67 eptide, and subsequent Michael addition with cysteamine increased masses by the predicated 77 and 154
70 bilayer and semi circled DDA on the MPA and cysteamine layers were confirmed by the increased redox
73 opamine by the RNA aptamer, immobilized at a cysteamine-modified Au electrode, and further electroche
74 interactions between the positively charged cysteamine-modified electrode and the negatively charged
76 be performed by the RNA aptamer tethered to cysteamine-modified gold electrodes via the alkanethiol
79 , heme oxygenase-1, neutrophil infiltration, cysteamine, mucin, hydrogen sulfide, ghrelin, adiponecti
80 e chain elongation intermediates as N-acetyl cysteamine (NAC) thioesters and have used them as substr
81 e synthesis of taurine, the final product of cysteamine oxidation and the second most abundant amino
82 rophage cultures revealed that cystamine and cysteamine possess significant antiviral properties at n
83 with 70 mol % mercaptopropanol and 30 mol % cysteamine/propanedithiol to facilitate membrane fusion
85 ults, treatment of cultured macrophages with cysteamine reduced cellular generation of reactive oxyge
86 rs (e.g., DMSO, glycerol, and cationic thiol cysteamine) reduces the incidence of instability after i
87 m and cystamine, diethyl dithiocarbamate and cysteamine, respectively, were found to be ineffective a
88 erestingly, exposure of cells to cysteine or cysteamine resulted in elevated intracellular hypotaurin
89 cystinotic cells' cystine content by use of cysteamine results in normalization of the apoptotic rat
90 unosensor for the detection of MDM2 based on cysteamine self assembled monolayers on a clean polycrys
93 ite-directed mutagenesis indicate that SIGC(-cysteamine) specifically and efficiently leads to cystea
94 od an aptamer was used to aggregate cationic cysteamine-stabilized CdTe/ZnS core/shell quantum dots,
95 Other antioxidants, approved for human use (cysteamine, succimer, dimercaprol), were not efficacious
96 utants in the presence of a concentration of cysteamine that elicits an intracluster open probability
101 In a study of renal ischemia reperfusion, cysteamine therapy initiated 10 days after injury and co
103 de that serves as a chemical intermediate in cysteamine therapy of cystinosis, and PQLC2 gene silenci
104 adulthood and the effects of long-term oral cysteamine therapy on its nonrenal complications have no
105 who received long-term (> or =8 years) oral cysteamine therapy were taller and heavier, had a renal
107 eaction of some of its epoxide moieties with cysteamine to afford a monolith rich in surface thiol gr
108 hrough reaction of its epoxide moieties with cysteamine to afford a monolith rich in surface thiol gr
111 displayed more severe lesions in response to cysteamine treatment compared with wild-type counterpart
112 othyroidism, and death increased as time off cysteamine treatment increased, and it decreased as time
113 viously unrecognized antifibrotic actions of cysteamine via TGF-beta-independent mechanisms that incl
115 phosphopantetheine, pantetheine, and finally cysteamine was observed with ThnR, ThnH, and ThnT, respe
116 onyl-S-pantetheine or L-threonyl-S-(N-acetyl)cysteamine was used as a small-molecule thioester analog
117 st successful of these biomimetic catalysts (cysteamine) was used to encapsulate firefly luciferase,
118 athione, and the simplest stable aminothiol, cysteamine, we enabled the nanoparticles to exhibit not
119 2+/-0.2 mM for L-serine and 5.6+/-2.2 mM for cysteamine, with kcat = 1.3+/-0.1s(-1) for the formation
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