ライフサイエンスコーパス: cystoblast

1 SC) and their differentiated daughter cells (cystoblasts).

2 asymmetrically, producing another GSC and a cystoblast.

3 tem cell produces a daughter stem cell and a cystoblast.

4 ifferentiation of the stem cell progeny, the cystoblast.

5 ct regulator of the switch from stem cell to cystoblast.

6 ach other in reciprocal patterns in GSCs and cystoblasts.

7 -contacting PGCs directly differentiate into cystoblasts.

8 differentiation of immediate GSC daughters, cystoblasts.

9 m cells and the immediate descendents called cystoblasts.

10 ary regulators of bam expression in GSCs and cystoblasts.

11 ls, apparently by inducing them to divide as cystoblasts.

12 lls and high levels of Nanos in the dividing cystoblasts.

13 In cystoblasts, accumulating Bam protein antagonizes pumili

14 rosomes that anchor the spindles of dividing cystoblasts, and at the nuclear rim of the developing oo

15 ling, one GSC daughter differentiates into a cystoblast (CB) and this fate is stabilised by Brain tum

16 l, causing it to switch to a differentiating cystoblast (CB).

17 with the CpCs, and a more posterior located cystoblast (CB).

18 at fusome biogenesis is an obligate step for cystoblast cell fate and that Bam is the limiting factor

19 ndicate that, like bam, bgcn is required for cystoblast development and that germ cells lacking bgcn

20 ranous cisternae within the fusome and block cystoblast differentiation altogether.

21 est that Bam and Bgcn cooperatively regulate cystoblast differentiation by controlling localization o

22 n of TER94 is Bam-dependent, suggesting that cystoblast differentiation may be linked to fusome retic

23 nts that are necessary for activation of the cystoblast differentiation program.

24 sion of SXL, which in turn causes defects in cystoblast differentiation similar to the Bruno mutant p

25 Mutations in genes required for cystoblast differentiation, such as bag-of-marbles, bloc

26 he relationship between fusome cisternae and cystoblast differentiation, we have begun to identify ot

27 To understand how Bruno controls cystoblast differentiation, we used a bioinformatics app

28 whereas bag-of-marbles (bam) is required for cystoblast differentiation.

29 hat bam is both necessary and sufficient for cystoblast differentiation.

30 diated translational repression required for cystoblast differentiation.

31 dicates that bam expression is necessary for cystoblast differentiation; bam mutant germ cells fail t

32 produced eggs, indicating that stem-cell and cystoblast divisions in the female germline do not requi

33 arbles (bam) gene as an intrinsic factor for cystoblast fate in Drosophila germline cells and shown t

34 ssed, probably because they cannot adopt the cystoblast fate.

35 ila germ line stem cell differentiation to a cystoblast is gradual.

36 ion that germ cells lacking bgcn cannot form cystoblasts is that bgcn stem cells resist genetic ablat

37 SC) to its differentiated daughter cell, the cystoblast, is controlled by both niche signals and intr

38 ed for the four synchronous divisions of the cystoblast leading to cyst formation.

39 Thus, stem cells/cystoblasts of the adult ovary are capable of forming st

40 The cystoblast produces a syncytial cluster of 16 cells by p

41 ntagonize Nos expression; thus, derepressing cystoblast-promoting factors.

42 nizes pumilio, permitting the translation of cystoblast-promoting transcripts.

43 tional repressors Nanos and Pumilio, whereas cystoblasts require the bam and bgcn genes.

44 some, a cytoplasmic structure that spans the cystoblast's progeny that develop to form a germline cys

45 generate a daughter germline stem cell and a cystoblast that will develop into a mature egg.

46 invariably divide asymmetrically to produce cystoblasts that proceed normally through oogenesis-rema

47 Bruno is required for the differentiation of cystoblasts, the committed daughters of germline stem ce

48 asymmetrically to produce daughter GSCs and cystoblasts, the latter of which develop into germline c

49 The cystoblast then divides and matures into an oocyte, a pr

50 es in a 16-cell syncytium that arises from a cystoblast which undergoes 4 synchronous divisions with

51 ng indicator, is restricted to GSCs and some cystoblasts, which have repressed bam expression.