ライフサイエンスコーパス: cytochrome

1 the latter two pathways have iron-requiring cytochromes.

2 evelopment, but express residual murine p450 cytochromes.

3 ing as a substitute for outer-surface c-type cytochromes.

4 membrane-bound heterodisulfide reductase and cytochromes.

5 oxidases, a cytochrome bd-type (CydAB) and a cytochrome aa 3-type menaquinol (QoxAB) oxidase, and tha

6 aquinone:cytochrome c reductase (bc1 ) and a cytochrome aa3 -type oxidase.

7 l DNA (mtDNA) cytochrome oxidase I (COI) and cytochrome b (Cyt b) gene markers, we inferred the origi

8 ely cytochrome c oxidase subunit I (COI) and cytochrome b (cytb), were analysed in silico to identify

9 Cytochrome b 5 (cytb 5) is a membrane protein vital for

10 omplex formation depended on the presence of cytochrome b and Cox3, supporting the idea that supercom

11 ected to an NGS approach targeting two short cytochrome b gene (cytb) fragments on the Illumina MiSeq

12 ain reaction (PCR) (nested PCR targeting the cytochrome b gene) and quantitative PCR as reference sta

13 16S rDNA, 28S rDNA, Cytochrome oxidase I and Cytochrome b).

14 Species-specific primers were designed from cytochrome b, cytochrome oxidase I, and 16S rRNA genes t

15 l methods, i.e. Hake-ITS1-RFLP (89%) or Hake-Cytochrome b-RFLP (83%).

16 amined are enhanced by the accessory protein cytochrome b5 (b5), but the exact role of b5 in P450 17A

17 The small heme-containing protein cytochrome b5 can facilitate, inhibit, or have no effect

18 ull-length mammalian 72-kDa cytochrome P450-cytochrome b5 complex in lipid bilayers.

19 in vascular smooth muscle cells reveal that cytochrome b5 reductase 3 expression and activity is cri

20 Cytochrome b5, which augments several P450 activities, i

21 s and revealed the transmembrane topology of cytochrome b5.

22 the cytosolic surface of PSII directly above cytochrome b559, in close proximity to the QB site.

23 The A2A receptor with a cytochrome b562-RIL (BRIL) fusion (A2AR-BRIL) in the int

24 ieske FeS protein (PetC), a component of the cytochrome b6f (cyt b6f) complex.

25 ced mutant hcf222-1, the accumulation of the cytochrome b6f (Cytb6f) complex was reduced to 30% compa

26 short-range interactions with Complex I and cytochrome b6f are excluded from these regions of the me

27 stohydroquinone catalyzed by the chloroplast cytochrome b6f This intermediate state is formed by inte

28 At the protein level, ferredoxin, the cytochrome-b6f complex, and Fe-containing enzymes of the

29 widespread quinone oxido-reductases from the cytochrome bc family limit the amounts of released ROS t

30 ve phosphorylation system, in particular the cytochrome bc1 (complex III)-cytochrome c oxidase (compl

31 clinical development of drugs targeting the cytochrome bc1 :aa3 , as well as for the development of

32 The mycobacterial cytochrome bc1 :aa3 consists of a menaquinone:cytochrome

33 t discovery of small molecules targeting the cytochrome bc1 :aa3 in Mycobacterium tuberculosis trigge

34 luding inhibition of the QcrB subunit of the cytochrome bc1 complex, disruption of cell-wall homeosta

35 herichia coli cells harbouring CpcA-labelled cytochrome bd 1 ubiquinol oxidase in the cytoplasmic mem

36 around E. coli that identified high-affinity cytochrome bd oxidase as an essential bacterial gene pro

37 noculated with E. coli mutants defective for cytochrome bd oxidase did not.

38 , we show that the electron flow through the cytochrome bd oxidase is sufficient to maintain respirat

39 that the alternate terminal bd-type oxidase (cytochrome bd oxidase) is capable of maintaining a membr

40 Upon genetic deletion of the cytochrome bd oxidase-encoding genes cydAB, Q203 inhibit

41 . monocytogenes has two terminal oxidases, a cytochrome bd-type (CydAB) and a cytochrome aa 3-type me

42 Cytochrome bo3 is a respiratory proton-pumping oxygen re

43 (CcP)], suggesting both ascorbate (Asc) and cytochrome c (Cc) peroxidase activity.

44 rving as respiratory electron shuttle, ferri-cytochrome c (cyt c) acts as a peroxidase; i.e., it cata

45 d, catalytic circuit based on photosystem I, cytochrome c (cyt c) and human sulfite oxidase (hSOX).

46 cribe advancements in sensing technology for cytochrome c (cyt c) detection, at point-of-care (POC) a

47 CRALBP and cytochrome C (Cyt C) immunolabeling revealed that hyperr

48 It is well known that cytochrome c (Cyt c) is a crucial death regulator that t

49 Cytochrome c (cyt c) is a small soluble heme protein cha

50 Cytochrome c (Cyt c) is commonly used as intrinsic bioma

51 The multifunctional protein cytochrome c (cyt c) plays key roles in electron transpo

52 Globular proteins, such as cytochrome c (cyt c), display an organized native confor

53 Cytochrome c (cyt c), required for electron transport in

54 gly, D62-DPPC acyl chains were unaffected by cytochrome c accumulation, while cardiolipin showed majo

55 mbrane potential loss, increase of cytosolic cytochrome c and Bax levels, decrease of Bcl-2 levels an

56 er resolution images of individual proteins (cytochrome C and BSA) as well as of protein complexes (h

57 Cytochrome c and p53-related apoptosis mechanisms were i

58 of mitochondrial activity by phosphorylated cytochrome c and to develop novel therapeutic approaches

59 Here we mimic phosphorylation of cytochrome c by replacing tyrosine 48 with p-carboxy-met

60 It was recently shown that cytochrome c can induce pore formation in cardiolipin-co

61 ESI-QTOF-MS technique, formation of glycated cytochrome C containing up to 12 glucose moieties were o

62 onality: The phosphomimetic mutation impairs cytochrome c diffusion between respiratory complexes, en

63 after three initial reports of NECD from the cytochrome c dimer complex, no further evidence of the e

64 y 20-fold larger than the previously studied cytochrome c dimer.

65 e detection of apoptosis based on release of cytochrome c from mitochondria in lysates human embryoni

66 Escherichia coli cells harbouring wild-type cytochrome c from Rhodothermus marinus (Rma cyt c) were

67 ases are often activated upon the release of cytochrome c from the mitochondria, which is promoted by

68 Cytochrome C had multiple charges in non-glycated state,

69 e basal portion of the RPE, as identified by cytochrome C immunoreactivity, and that the hyporeflecti

70 The distribution pattern of cytochrome c in individual cells was used as a measure o

71 depicts a low barrier for the permeation of cytochrome C into the Bax C-terminal mouth, with the pat

72 collision cross sections of native-like, 7+ cytochrome c ions increase monotonically from 15.1 to 17

73 How cytochrome C is released from the mitochondria to the cy

74 ologous, nucleus-, and mitochondrion-encoded cytochrome c maturase systems.

75 bacteria, including Rhodobacter capsulatus, cytochrome c maturation (Ccm) is carried out by a membra

76 suggesting loss of the entire mitochondrial cytochrome c maturation pathway from Ophioglossum.

77 Cytochrome c oxidase (CcO) catalyzes the reduction of ox

78 Cytochrome c oxidase (CcO) is a transmembrane protein th

79 Proton pumping A-type cytochrome c oxidase (CcO) terminates the respiratory ch

80 Cytochrome c oxidase (CcO), the terminal enzyme in the e

81 ctor of the mitochondrial respiratory enzyme cytochrome c oxidase (CcO).

82 particular the cytochrome bc1 (complex III)-cytochrome c oxidase (complex IV) supercomplex (termed I

83 itochondrial protein with essential roles in cytochrome c oxidase (COX) assembly and the regulation o

84 Cytochrome c oxidase (COX) was initially purified more t

85 Copper is required for the activity of cytochrome c oxidase (COX), the terminal electron-accept

86 tes to fail in the assembly of mitochondrial cytochrome c oxidase (COX).

87 ction by measuring H2O2, lipid peroxidation, cytochrome c oxidase activity and mitochondrial ATP.

88 synthase activity was lower (P < 0.0001) and cytochrome c oxidase activity per Mt unit was higher (P

89 itochondrial respiratory chain complex IV or cytochrome c oxidase activity.

90 tected the activity of mitochondrial enzymes cytochrome c oxidase and aconitase in differentiating NS

91 tected the activity of mitochondrial enzymes cytochrome c oxidase and aconitase.

92 otein synthesis but rather have a problem in cytochrome c oxidase complex (COX) assembly.

93 Proton transfer in cytochrome c oxidase from the cellular inside to the bin

94 Here, metabarcoding of cytochrome c oxidase I (COI) region of mitochondrial DNA

95 nd decreased levels of mitochondrial complex cytochrome c oxidase I/IV and lower ATP levels.

96 on function (Q) of the redox center CuA from cytochrome c oxidase is attained by tuning the accessibi

97 ong with a correlation between the number of cytochrome c oxidase operons and heterotrophic or diazot

98 Defects in mitochondrial cytochrome c oxidase or respiratory chain complex IV (CI

99 unravel the use of the mitochondrial marker cytochrome c oxidase subunit 1 (coxI) as barcode for Lon

100 in a stretch of 22 identical amino acids in cytochrome c oxidase subunit 1 and NADH dehydrogenase su

101 voltage-dependent anion channel (VDAC), and cytochrome c oxidase subunit 4 (COX IV).

102 Two DNA barcode regions, namely cytochrome c oxidase subunit I (COI) and cytochrome b (c

103 Pyrosequencing of genetic marker, COI (cytochrome c oxidase subunit I) and subsequent sequence

104 Conditional deletion of cytochrome c oxidase, the terminal enzyme in the respira

105 d inhibition are significantly attenuated in cytochrome c oxidase-deficient mice.

106 Cytochrome c oxidases of facultative members of the comm

107 cbb3-type cytochrome c oxidases, which catalyze the terminal step

108 Ubiquinol cytochrome c oxidoreductase (bc1 complex) serves as an i

109 e, the flexible pore may selectively aid the cytochrome C passage.

110 ndrial respiration via the energy-conserving cytochrome c pathway in both strains, the mutant was una

111 idopsis (especially after restriction of the cytochrome c pathway) but cannot compensate for the lack

112 A member of class I heme peroxidases [TcAPx-cytochrome c peroxidase (CcP)], suggesting both ascorbat

113 Microbial cytochrome c peroxidases (Ccp) have been studied for 75

114 Although cytochrome c phosphorylation-in particular, at tyrosine

115 When the vesicle-associated cytochrome c Raman spectrum is compared with a spectrum

116 ytochrome bc1 :aa3 consists of a menaquinone:cytochrome c reductase (bc1 ) and a cytochrome aa3 -type

117 In this work, cytochrome c reductase (CcR) biofunctionalized self asse

118 fide bond cross-link caused a >/=95% loss of cytochrome c reductase activity that was reversible with

119 function of the subunit b of the menaquinone:cytochrome c reductase.

120 Superoxide generation was measured by cytochrome C reduction in the presence and absence of N-

121 chondrial outer membrane (MOM), which causes cytochrome c release and apoptosis.

122 o the MOM bypasses the need for Mff to evoke cytochrome c release, and occludes the effect of SENP3 o

123 both Drp1 binding to Mff and stress-induced cytochrome c release.

124 spases activation, Bcl-xL sequestration, and cytochrome c release.

125 ubunits: the catalytic CcoN subunit, the two cytochrome c subunits (CcoO and CcoP) involved in electr

126 Rather than inert passing of the cytochrome C through a rigid pore, the flexible pore may

127 insight in atomic detail into the release of cytochrome C through Bax oligomeric pores.

128 on proceeds through selective interaction of cytochrome c with cardiolipin, resulting in protein unfo

129 To verify selective interactions of cytochrome c with cardiolipin, these experiments were re

130 In this work, the interaction of cytochrome c with cardiolipin-containing phospholipid ve

131 isotopes at the fundamental distribution of cytochrome c(+8) (m/z approximately 1549) were nearly ba

132 Bax expression, a disturbed distribution of cytochrome c, and cleaved caspase-3 positive staining in

133 CRALBP, cytochrome C, and GNB3 showed that the RPE interdigitati

134 apped, translated into a solution containing cytochrome c, and monitored for 3-NBS leakage.

135 erobic electron acceptors include oxygen and cytochrome c, but an acceptor that can function under an

136 electrons coming from NADH and ubiquinol to cytochrome c, but it is also capable of producing signif

137 ria differed primarily at a Raman biomarker, cytochrome c, corresponding to a bacteroid-specific term

138 The glycated species of cytochrome C, lysozyme, and beta-casein formed during gl

139 pathological changes and increased levels of cytochrome c, Smac/DIABLO and AIF in the cytosol while t

140 imilar to the previously reported results on cytochrome c, these fragment ions form near residues kno

141 the SH3 domain, dihydrofolate reductase, and cytochrome c, where the transparent window vibrational p

142 models of the OMM, is investigated to probe cytochrome c-induced permeability.

143 induce cell death through direct release of cytochrome c.

144 an enhanced ability to transfer electrons to cytochrome c.

145 reactivity of the reduced FMN domain toward cytochrome c; (v) response to calmodulin binding; and (v

146 e cofactors (hemes b and copper for CcoN and cytochromes c for CcoO and CcoP) were present within the

147 The mesh is functionalized with cytochrome-c (cyt-c) and incorporated as a working elect

148 Muscle studies showed global cytochrome-c oxidase deficiency in all patients tested a

149 not lead to cerebral caspase-3 activation or cytochrome-c release.

150 the oxidation state of mitochondrial enzyme cytochrome-c-oxidase (oxCCO) have the potential to yield

151 Cytochrome-correlated leakage was observed only in cardi

152 The cytochrome (cyt) b6f complex and Stt7 kinase regulate th

153 tosystem I (PSI), photosystem II (PSII), and cytochrome (Cyt) b6f within thylakoid membranes at the m

154 dehydrogenase was fused to a natural minimal cytochrome domain in its c-terminus to achieve direct el

155 t has inherently higher transcript levels of cytochrome enzymes (Cyp2d3, Cyp2d5, and Cybrd1, which ca

156 These results suggest that cytochrome-induced permeabilization proceeds through sel

157 letion of Adrb2 and Cox10, a gene encoding a cytochrome IV oxidase assembly factor, prevented the met

158 nd reduces oxygen to water without involving cytochrome-linked electron transport chain.

159 e Por gene in the liver, and show that human cytochrome metabolism is used following repopulation wit

160 deleted (<5%), they predominantly use human cytochrome metabolism.

161 The decaheme cytochrome MtrC from Shewanella oneidensis MR-1 immobili

162 and hydrogenases, formate dehydrogenase, and cytochromes of Desulfovibrio were found in high abundanc

163 divisions of the IC were identified based on cytochrome oxidase (CO) histochemistry.

164 d 4B send segregated projections to distinct cytochrome oxidase (CO) stripes in area V2: neurons in C

165 NADPH-d), glutamic acid decarboxylase (GAD), cytochrome oxidase (CO), and calretinin (CR).

166 The yeast bc1 complex (complex III) and cytochrome oxidase (complex IV) are mosaics of core subu

167 o of the candidate glycoproteins identified (cytochrome oxidase 2 (COX2) and NADH:ubiquinone oxidored

168 ity trade data and mitochondrial DNA (mtDNA) cytochrome oxidase I (COI) and cytochrome b (Cyt b) gene

169 exhibited 98-100% partial mitochondrial DNA Cytochrome Oxidase I (mtCOI) gene identity with the B. t

170 es of four genetic loci (16S rDNA, 28S rDNA, Cytochrome oxidase I and Cytochrome b).

171 diversity, and large-scale mitochondrial DNA cytochrome oxidase I barcoding has exposed many potentia

172 on a single locus, the barcode region in the cytochrome oxidase I mitochondrial gene, and analyzed re

173 fic primers were designed from cytochrome b, cytochrome oxidase I, and 16S rRNA genes to generate PCR

174 Consistent with cytochrome oxidase involvement, the glycolytic effect wa

175 barcoding region of the mitochondrial gene, cytochrome oxidase subunit I (COI), is highly variable a

176 on by covalent modification of mitochondrial cytochrome oxidase, a phenomenon of pathological relevan

177 seal and sea lion pups for Nissl substance, cytochrome oxidase, and vesicular glutamate transporters

178 ssembled 104 complete body maps, revealed by cytochrome-oxidase activity in layer 4 of 8 rodent and 1

179 lutamate transporter-2, which suggested that cytochrome-oxidase maps closely mirror thalamic innervat

180 omical organization, initially defined using cytochrome-oxidase staining of post-mortem tissue.

181 chrome P-450 2D6, encoded by the polymorphic cytochrome P-450 2D6 gene (CYP2D6), oxidizes tamoxifen t

182 Cytochrome P-450 2D6, encoded by the polymorphic cytochr

183 multiple xenobiotic response genes, such as cytochrome P-450 and glutathione S-transferases, potenti

184 MicroRNAs (miRNAs) that regulate the cytochrome P-450 isoforms involved in acetaminophen (APA

185 Prodrug-mediated utilization of the cytochrome P450 (CYP) 1A1 to obtain the selective releas

186 in vitro assessment confirmed inhibition of cytochrome P450 (CYP) 2C19 and CYP3A4 by meropenem, sugg

187 Cytochrome P450 (CYP) 3A accounts for nearly 30% of the

188 Here we have begun to uncover the effects of cytochrome P450 (CYP) 4A in TAMs on lung pre-metastatic

189 om the crosstalk between endocannabinoid and cytochrome P450 (CYP) epoxygenase metabolic pathways.

190 Cytochrome P450 (CYP) family members are known to be pre

191 polyunsaturated fatty acids derived from the cytochrome P450 (CYP) monooxygenase pathway serve as vit

192 Cytochrome P450 (CYP)1A enzymes are protective against h

193 Multiple cytochrome P450 (CYP1A1, CYP2A19 and CYP2C36) genes disp

194 d pheromones in the MG, including members of cytochrome P450 (CYP450) family and genes involved in fa

195 Intracellular enzymes, such as cytochrome P450 (CYP450), have also been suggested to co

196 maize PLASTOCHRON1 (ZmPLA1) gene, encoding a cytochrome P450 (CYP78A1), results in increased organ gr

197 membrane protein vital for the regulation of cytochrome P450 (cytP450) metabolism and is capable of e

198 Cytochrome P450 (P450) 17A1 catalyzes the oxidations of

199 Recently, zebrafish and human cytochrome P450 (P450) 27C1 enzymes have been shown to b

200 Cytochrome P450 (P450, CYP) 17A1 plays a critical role i

201 Cytochrome P450 (P450, CYP) 21A2 is the major steroid 21

202 Aldosterone synthase (AS, cytochrome P450 11B2, cyp11B2) is the sole enzyme respon

203 The clinical utility of inhibiting cytochrome P450 17A1 (CYP17), a cytochrome p450 enzyme t

204 describes the linkage between inhibition of cytochrome P450 19A aromatase (the MIE) and population-l

205 Cytochrome P450 27A1 (CYP27A1 or sterol 27-hydroxylase)

206 Cytochrome P450 27A1 (CYP27A1) is a ubiquitous enzyme th

207 Human cytochrome P450 3A4 (CYP3A4) is a major hepatic and inte

208 Inhibition of cytochrome P450 3A4 (CYP3A4), the major drug metabolizin

209 The contributions of cytochrome P450 3A5 to the metabolic clearance of market

210 Cytochrome P450 46A1 (CYP46A1, cholesterol 24-hydroxylas

211 By the time cytochrome P450 7A1 expression is reduced these drugs ma

212 or hepatocellular bile salt transporters and cytochrome P450 7a1, the key regulator of bile salt synt

213 explained by the effect of the two azoles on cytochrome P450 activity, measured on D. magna in vivo.

214 inal chemists to stabilize candidates toward cytochrome P450 activity, which increases the risk for n

215 Surprisingly, this cytochrome P450 also catalyzes the non-oxidative isomeri

216 Here we provide evidence that cytochrome P450 aromatase (AROM), the enzyme converting

217 which reportedly regulates the expression of cytochrome P450 aromatase (P450arom).

218 in mood disorders and of the side effects of cytochrome P450 aromatase inhibitors, which are frequent

219 an facilitate, inhibit, or have no effect on cytochrome P450 catalysis, often in a P450-dependent and

220 ction, we have prepared a selenolate-ligated cytochrome P450 compound I intermediate.

221 Although the cytochrome P450 CYP27B1 plays a critical role in vitamin

222 The role of cytochrome P450 drug metabolizing enzymes in the efficac

223 ls suggest that changes in the production of cytochrome P450 eicosanoids alter BP.

224 review summarizes the emerging evidence that cytochrome P450 eicosanoids have a role in the pathogene

225 raenoic acid (20-HETE), one of the principle cytochrome P450 eicosanoids, is a potent vasoactive lipi

226 orometric method was used to compare general cytochrome P450 enzyme activity by monitoring the transf

227 arvae relative to adults may be due to lower cytochrome P450 enzyme activity in fat bodies.

228 Here we report the engineering of a cytochrome P450 enzyme by directed evolution to catalyze

229 (1,25(OH)2D3), occurs in the kidney via the cytochrome P450 enzyme CYP27B1.

230 CYP121, the cytochrome P450 enzyme in Mycobacterium tuberculosis tha

231 Sterol 14alpha-demethylase (CYP51) is a cytochrome P450 enzyme required for biosynthesis of ster

232 fungi using azole compounds that inhibit the cytochrome P450 enzyme sterol 14alpha-demethylase.

233 characterization of vinorine hydroxylase, a cytochrome P450 enzyme that hydroxylates vinorine to for

234 f inhibiting cytochrome P450 17A1 (CYP17), a cytochrome p450 enzyme that is required for the producti

235 o deliver the desired outcome, an engineered cytochrome P450 enzyme was employed to effect a chemo- a

236 ay for the metabolism of arachidonic acid by cytochrome P450 enzymes emerged.

237 Cytochrome P450 enzymes have been engineered to catalyze

238 in biosynthesis, including ABC transporters, cytochrome P450 enzymes, and an acyltransferase.

239 se (CPR) is the redox partner for most human cytochrome P450 enzymes.

240 In contrast, pharmacological inhibition of cytochrome P450 epoxygenases opened the myocardial mPTP

241 ify novel phenotypic associations related to Cytochrome P450 Family 2 Subfamily A Member 6 (CYP2A6),

242 D responsive genes, 25(OH)D3-24-hydroxylase (cytochrome P450 family 24 subfamily A member 1) mRNA exp

243 ry low level of 25(OH)D3-1alpha-hydroxylase (cytochrome P450 family 27 subfamily B member 1), and the

244 Enzymes belonging to the cytochrome P450 family have an essential role in creatin

245 ither pitavastatin nor pravastatin depend on cytochrome P450 for primary metabolism.

246 iption analysis identified overexpression of cytochrome P450 genes as the main mechanism driving this

247 n-donation from the axial thiolate ligand of cytochrome P450 has been proposed to increase the reacti

248 , improving metabolic stability and reducing cytochrome P450 inhibition driven drug-drug interaction

249 ed Nrf2-luc response were ameliorated by the cytochrome P450 inhibitor aminobenzotriazole.

250 e (CBR-096-4) devoid of antifungal and human cytochrome P450 inhibitory activity with excellent pharm

251 ther taxa, NMP is primarily detoxified via a cytochrome P450 mediated pathway.

252 ntial for drug interactions due to competing cytochrome P450 metabolism between statins and commonly

253 Using a LC-MS method, putative cytochrome P450 metabolites of NMP were identified and q

254 Cytochrome P450 monooxygenase was involved in the produc

255 ron-containing enzymatic catalyst-based on a cytochrome P450 monooxygenase-for the highly enantiosele

256 own inhibitors of the important enzyme class cytochrome P450 monooxygenases (CYPs), thereby influenci

257 Cytochrome P450 monooxygenases (P450) in the honey bee,

258 extremely large repertoire of genes encoding cytochrome P450 monooxygenases and glutathione S-transfe

259 erentially expressed genes (DEGs), including cytochrome P450 monooxygenases and UDP-glycosyltransfera

260 Cytochrome P450 monooxygenases CYP101A1 and MycG catalyz

261 Cytochrome P450 monooxygenases play a critical role in i

262 The Jeotgalicoccus sp. peroxygenase cytochrome P450 OleTJE (CYP152L1) is a hydrogen peroxide

263 he omega-3 and the omega-6 lipid products of cytochrome P450 oxidase 2C promote neovascularization in

264 l functional replicas of the peroxidases and cytochrome P450 oxidizing enzymes.

265 enzyme reduction by the redox partner NADPH-cytochrome P450 oxidoreductase, and the amount of P450 r

266 ereas anti-inflammatory metabolites from the cytochrome P450 pathway were reduced in cART/HIV-1-expos

267 It lacks all genes encoding heme-containing cytochrome P450 proteins.

268 nd CYP6AA7 were separately co-expressed with cytochrome P450 reductase (CPR) in insect Spodoptera fru

269 Cytochrome P450 reductase (CPR) is the redox partner for

270 nctioned as type I nitroreductase (TbNTR) or cytochrome P450 reductase (TbCPR) dependent prodrugs tha

271 NADPH-cytochrome P450 reductase is a multi-domain redox enzyme

272 one synthetase, glutathione reductase, NADPH-cytochrome P450 reductase, biliverdin reductase, and thi

273 nhibit warfarin deactivation via the hepatic cytochrome P450 system.

274 apsigargin biosynthesis, by showing that the cytochrome P450 TgCYP76AE2, transiently expressed in Nic

275 le of CYP46A1, an important brain enzyme and cytochrome P450 that could be activated pharmacologicall

276 ) is metabolized by cyclooxygenase (COX) and cytochrome P450 to produce proangiogenic metabolites.

277 Additionally, 16 cytochrome P450 transcripts related to secondary metabol

278 s ago to help explain reactivity patterns in cytochrome P450, and subsequently has been used to provi

279 process is dependent on hepatic induction of cytochrome P450, family 7, subfamily b, polypeptide 1 (C

280 Cytochrome P450-2E1 (CYP2E1) increases oxidative stress.

281 synthesis, which involves a uniquely adapted cytochrome P450-amidotransferase enzyme pair and highlig

282 Biosynthetic pathways involving cytochrome P450-catalyzed oxidation of fatty acids in ye

283 nteractions of full-length mammalian 72-kDa cytochrome P450-cytochrome b5 complex in lipid bilayers.

284 of in vivo glycosylation, selective in vitro cytochrome P450-mediated oxidation, and chemical oxidati

285 ct metabolism-an alcohol dehydrogenase and a cytochrome P450-produces unexpected rearrangements in st

286 Cytochrome P450-reductase (CPR) is a versatile NADPH-dep

287 d alpha-linolenic acid, respectively) in the cytochrome P450/soluble epoxide hydrolase pathway.

288 Subsequently, deletion of two cytochromes P450 in the dynemicin cluster suggested that

289 cterium tuberculosis H37Rv genome encodes 20 cytochromes P450, including P450s crucial to infection a

290 AHR activation induces cytochrome P4501 (CYP1) enzymes, which oxygenate AHR lig

291 enobiotic metabolizing enzyme genes, notably cytochrome P4501A1 encoded by CYP1A1, in response to the

292 Expression of liver cytochrome P4502E1 did not correlate with TCA levels.

293 Cytochrome P450cam (CYP101Fe(3+)) regioselectively hydro

294 Previous crystal structures of cytochrome P450cam complexed with its redox partner, put

295 The most up-regulated genes include cytochrome P450s (CYP) CYP6P9a, CYP6P9b and CYP6M7.

296 luated whether tyrosine hydroxylase (TH) and cytochrome P450s (CYPs) catalyzed this process.

297 cluding the drug-metabolizing enzymes of the cytochrome P450s (P450).

298 Here, we report the discovery of five cytochrome P450s and two acetyltransferases which cataly

299 Many family 4 cytochrome P450s play key roles in fatty acid hydroxylat

300 mutant lacking a trans-outer membrane porin-cytochrome protein complex required for direct intercell

301 dings demonstrate the potential of multiheme cytochromes to catalyze technologically relevant reactio