ライフサイエンスコーパス: cytochrome b

1 16S rDNA, 28S rDNA, Cytochrome oxidase I and Cytochrome b).

2 Atovaquone targets parasite cytochrome b.

3 nits and the mitochondrially encoded subunit cytochrome b.

4 eveals the presence of the Y268S mutation in cytochrome b.

5 eakened interaction between this subunit and cytochrome b.

6 ansfer to the Rieske iron-sulfur protein and cytochrome b.

7 ion, which eliminates the proton acceptor in cytochrome b.

8 mitochondrial components, cytochrome c, and cytochrome b.

9 cripts for cytochrome oxidase II (COXII) and cytochrome b.

10 These cysts highly express cytochrome b.

11 lasmic mutation in a subunit of complex III, cytochrome b.

12 llowed by sequencing of a 201-bp fragment of cytochrome b.

13 ochondrial disease-related mutation in human cytochrome b.

14 ia a feedback loop that senses hemylation of cytochrome b.

15 nsformation of heme ligand sets reported for cytochrome bd.

16 herichia coli cells harbouring CpcA-labelled cytochrome bd 1 ubiquinol oxidase in the cytoplasmic mem

17 b light chain and encodes p22(phox) protein; cytochrome b-245 or NADPH oxidase 2, and encodes Nox2 or

18 dismutase, and NADPH oxidase-complex adaptor cytochrome b-245, alpha-polypeptide (p22phox) proteins,

19 ecies (ROS) because selective Cybb (encoding cytochrome b-245, beta polypeptide, also known as NOX2)

20 Cells containing a mitochondrial DNA cytochrome b 4-base-pair deletion ([rho(-)] cells) and c

21 Cytochrome b 5 (cytb 5) is a membrane protein vital for

22 cytochrome P450 reductase (CPR) and Mn(III) cytochrome b 5 (Mn cyt b 5); the manganese derivative of

23 ological partner proteins myoglobin (Mb) and cytochrome b(5) (b(5)) reveal interprotein ET rates comp

24 ently link cytochrome P450 2E1 (CYP2E1) with cytochrome b(5) (b(5)) through the formation of specific

25 The capacity of cytochrome b(5) (b(5)) to influence cytochrome P450 acti

26 nimals and contains three domains similar to cytochrome b(5) (b(5)), CHORD-SGT1 (CS), and cytochrome

27 of Zn-substituted myoglobin (Mb) variants to cytochrome b(5) (b(5)).

28 complex formation between myoglobin (Mb) and cytochrome b(5) (b(5)).

29 pation of cytochrome b(5) reductase (CYB5R), cytochrome b(5) (CYB5), and molybdenum cofactor sulfuras

30 me P450 2B4 were compared in the presence of cytochrome b(5) (cyt b(5)) and NADPH-cyt P450 reductase

31 tuted with Zn-deuteroporphyrin and monitored cytochrome b(5) (cyt b(5)) binding and electron transfer

32 Cytochrome b(5) (cyt b(5)) is one of the key components

33 [POR; HRN (hepatic reductase null) line] or cytochrome b(5) [HBN (hepatic cytochrome b(5) null) line

34 To investigate whether this is because cytochrome b(5) and cytochrome b(5) reductase can act as

35 ome b(5) oxidoreductase (Ncb5or), comprising cytochrome b(5) and cytochrome b(5) reductase domains, i

36 he spontaneous membrane insertion process of cytochrome b(5) and its mutants.

37 bicelles containing uniformly (15)N-labeled cytochrome b(5) are presented and theoretical analyses o

38 Cygb and demonstrate roles for ascorbate and cytochrome b(5) as reductants.

39 chrome b(5) has been deleted in all tissues [cytochrome b(5) complete null (BCN)], which surprisingly

40 ctivities were also significantly reduced by cytochrome b(5) deletion, leading to significantly lower

41 o the previous finding in the liver-specific cytochrome b(5) deletion, suggesting that extrahepatic c

42 However, neither AL10 nor AL21 contain the cytochrome b(5) domain normally present in this class of

43 Ncb5or is the first member of the cytochrome b(5) family shown to have such a heme environ

44 new insight into the factors stabilizing the cytochrome b(5) fold.

45 We have now generated a model in which cytochrome b(5) has been deleted in all tissues [cytochr

46 iver-specific deletion, complete deletion of cytochrome b(5) leads to a neonatal increase in the expr

47 ructure analysis reveals similarities to the cytochrome b(5) motif, neither of the two axial histidin

48 null) line] or cytochrome b(5) [HBN (hepatic cytochrome b(5) null) line].

49 NADH cytochrome b(5) oxidoreductase (Ncb5or) is found in anim

50 The endoplasmic reticulum-associated NADH cytochrome b(5) oxidoreductase (Ncb5or) is widely distri

51 NAD(P)H cytochrome b(5) oxidoreductase (Ncb5or), comprising cyto

52 n Leishmania, we attempted to create NAD(P)H cytochrome b(5) oxidoreductase from L. major (LmNcb5or)

53 b(5) deletion, suggesting that extrahepatic cytochrome b(5) plays a significant role in its disposit

54 We demonstrated recently that cytochrome b(5) plays an important in vivo role in hepat

55 Ascorbate and cytochrome b(5) reduce the oxidized Cygb-NOD intermediat

56 cytochrome b(5) (b(5)), CHORD-SGT1 (CS), and cytochrome b(5) reductase (b(5)R).

57 igate whether other reducing enzymes such as cytochrome b(5) reductase (b5R), cytochrome P450 reducta

58 ified enzymes suggested the participation of cytochrome b(5) reductase (CYB5R), cytochrome b(5) (CYB5

59 provide strong evidence that cytochrome b(5)/cytochrome b(5) reductase can act as a sole electron don

60 whether this is because cytochrome b(5) and cytochrome b(5) reductase can act as the sole electron d

61 ase (Ncb5or), comprising cytochrome b(5) and cytochrome b(5) reductase domains, is widely distributed

62 PH concentrations below the apparent K(m) of cytochrome b(5) reductase, but well above that for POR,

63 Several lines of evidence indicate that the cytochrome b(5) reductase-like protein controls the oxid

64 he growth defect caused by overexpression of cytochrome b(5) reductase-like protein could be partiall

65 t overexpressed gene encodes a mitochondrial cytochrome b(5) reductase-like protein.

66 Addition of cytochrome b(5) to CPR-supported l-Trp incubations resul

67 dipocytes, whereas down-regulation of MOSC1, cytochrome b(5) type A (CYB5A), CYB5R1, CYB5R2, or CYB5R

68 ation of MOSC2 and the mitochondrial form of cytochrome b(5) type B (CYB5B) significantly inhibited t

69 Ascorbate and cytochrome b(5) were found to support a high NOD activit

70 for P450 2D6 and P450 3A4 in the presence of cytochrome b(5) with (R)-reticuline as substrate.

71 elate the nonfunctional property of a mutant cytochrome b(5) with its inability to insert into the li

72 CPR-supported d-Trp oxidations (+/-cytochrome b(5)) exhibit Michaelis-Menten kinetics.

73 ther electron acceptors (artificial dyes and cytochrome b(5)).

74 y charge-clustered mutants of rat microsomal cytochrome b(5), E11Q and E44Q, with the same total char

75 shows respective K(m) values for ascorbate, cytochrome b(5), NO, and O(2) of 0.25 mm, 0.3 microm, 40

76 hich to further investigate the functions of cytochrome b(5), particularly in extrahepatic tissues.

77 tive SERR enhancement of the anionic protein cytochrome b(5), whereas functionalization with SiO(2) a

78 esterone receptor membrane component 1) is a cytochrome b(5)-related drug-binding orphan receptor ess

79 esterone receptor membrane component 1) is a cytochrome b(5)-related protein that is up-regulated in

80 p3 transmembrane domain with that of Acta or cytochrome b(5).

81 cs which can be modulated by the addition of cytochrome b(5).

82 etely unrelated membrane-targeting domain of cytochrome b(5).

83 These data provide strong evidence that cytochrome b(5)/cytochrome b(5) reductase can act as a s

84 adicals per PS II, and the yield of oxidized cytochrome b 559 by optical difference spectroscopy is 0

85 w that human erythrocyte membranes contain a cytochrome b(561) (Cyt b(561)) and hypothesize that it m

86 ythrocyte membranes showed only the duodenal cytochrome b(561) (DCytb) isoform.

87 ascorbate-regenerating electron transporter cytochrome b(561-1).

88 tion (CHGB, exon 4, Glu348Glu; P=0.002), and cytochrome b-561 (CYB561, intron 1, C719G; P<0.001), an

89 d the heme-binding electron transfer protein cytochrome b(562) (cyt b(562)).

90 omplication, we have engineered a variant of cytochrome b(562) (cyt c-b(562)) featuring a c-type link

91 eins, namely, the heme binding capability of cytochrome b(562) and the antibiotic degrading beta-lact

92 These observations suggest that the cytochrome b(562) folding energy landscape is minimally

93 was then replaced by a DNA cassette encoding cytochrome b(562) with differing linking sequences at ea

94 The folding of cytochrome b(562), a four-helix-bundle heme protein, is

95 sion proteins in a manner similar to that of cytochrome b(562).

96 haped relationship to the reduction state of cytochrome b(566), suggesting that superoxide production

97 s not required for catalytic turnover of the cytochrome b 6 f complex, the role of the single chlorop

98 ingle mutants Tyr112Phe and Trp125Leu in the cytochrome b 6 subunit.

99 reduced accumulation of the ATP synthase and cytochrome b ( 6 )/f complexes.

100 encoding the cytochrome b(6) subunit of the cytochrome b(6) f complex, was selected to expand our un

101 hown in single flash turnover experiments of cytochrome b(6) reduction and oxidation, the R214H mutat

102 single core genome locus, petB, encoding the cytochrome b(6) subunit of the cytochrome b(6) f complex

103 mponents of both photosystem I (PSI) and the cytochrome b(6)/f (Cyt b(6)/f) complex.

104 coexist within a large active photosystem I-cytochrome b(6)/f complex.

105 compared the lipid binding properties of the cytochrome b(6)f and bc(1) complexes that function in ph

106 also reported that the Chl a molecule in the cytochrome b(6)f complex does not change orientation in

107 The crystal structure of the cyanobacterial cytochrome b(6)f complex has previously been solved to 3

108 The accumulation of the cytochrome b(6)f complex is also strongly reduced to a l

109 The cyanobacterial cytochrome b(6)f complex is central for the coordination

110 SII but no change in the accumulation of the cytochrome b(6)f complex or photosystem I.

111 A native structure of the cytochrome b(6)f complex with improved resolution was ob

112 ells accumulate 14 to 20% less photosystems, cytochrome b(6)f complex, and ATP synthase but 30% more

113 However, the residual fraction of assembled cytochrome b(6)f complexes exhibits single-turnover elec

114 the presence of two distinguishable pools of cytochrome b(6)f complexes with different functions that

115 ential component of the cytochrome bc(1) and cytochrome b(6)f complexes, and it is exported across th

116 rising multiple subunits and many cofactors, cytochrome b(6)f from the chloroplast of the green alga

117 lic electron transport via photosystem I and cytochrome b(6)f is largely unaffected.

118 Accordingly, measurements of flash-induced cytochrome b(6)f turnover and respiration pointed to a r

119 Cytochrome b, a central catalytic subunit of complex III

120 pressure selects parasites with mutations in cytochrome b, a respiratory protein with low but essenti

121 Both are located on cytochrome b, a transmembrane protein of the bc1 complex

122 e p22 phagocytic oxidase subunit (p22(phox)) cytochrome b alpha gene (CYBA) C242T, crystallizable gam

123 We applied mtDNA cytochrome b and 11 microsatellite loci to 26 samples (N

124 n 300 samples were collected and analyzed at cytochrome b and 11 microsatellites loci for investigati

125 eractions between the Rieske protein and the cytochrome b and c sites and provide part of the driving

126 Using paired cytochrome b and control region data across individuals,

127 omplex formation depended on the presence of cytochrome b and Cox3, supporting the idea that supercom

128 refore, TtRp likely translocates between the cytochrome b and cytochrome c sites by passive diffusion

129 lity of the Fe/S protein to move between the cytochrome b and cytochrome c(1) subunits of the enzyme.

130 Rieske protein is mobile, moving between the cytochrome b and cytochrome c1 components during turnove

131 sulfur cluster in a conformation proximal to cytochrome b and distal to cytochrome c1.

132 is both required for efficient synthesis of cytochrome b and for protection of the newly synthesized

133 Tyr to Cys mutation cross-links together the cytochrome b and iron-sulfur subunits and renders the ba

134 e Q(o) site by weakening the binding between cytochrome b and ISP through hydrogen bonding provided b

135 when the iron-sulfur cluster is proximal to cytochrome b and minimizing binding of the product, redu

136 results suggest that functional variation in cytochrome b and NADH dehydrogenase could mechanisticall

137 ommunication between the two active sites of cytochrome b and open new possibilities for the utilizat

138 systems whereas two negative control genes (cytochrome b and peptidase inhibitor 3) show no signific

139 tterns of molecular evolution differ between cytochrome b and the control region.

140 the downregulation of the redox activity of cytochromes b and c in freezing yeast cells in a contact

141 lled protein structures of the mtDNA marker (cytochrome b) and estimated the environmental envelopes

142 mino N form H-bonds with conserved Asp228 of cytochrome b, and the formylamino O H-bonds via a water

143 inct step preceding transfer of electrons to cytochrome b, and with conformational gating models that

144 potency and identified the reduction site of cytochrome b as its cellular target.

145 We show that newly synthesized cytochrome b assembled through a series of four assembly

146 nt by locking the iron-sulfur subunit in its cytochrome b-binding conformation.

147 ssed mitochondrial precursor transcript (ND5-cytochrome b) but had no effect on steady-state levels o

148 hondria morphologic changes and reduction of cytochrome b/c.

149 he idea that alanine substitution at S322 of cytochrome b causes conformational changes at the Q(o) s

150 which we sequenced two mitochondrial genes, cytochrome b (cob) and cytochrome oxidase (cox1), for mu

151 is, we generated a data set of mitochondrial cytochrome b (cob) and mitochondrial cytochrome c oxidas

152 mitochondrial NADH dehydrogenase5 (nad5) and cytochrome b (cob) transcripts at the nad5-1550 and cob-

153 resulted in sequestration of Cbp3-Cbp6 in a cytochrome b-containing complex, thereby making Cbp3-Cbp

154 Its core subunit, cytochrome b, contains two sites, center P and center N,

155 The complex has a cytochrome b core and a central quinone exchange cavity,

156 evolves about 60% as rapidly as that of host cytochrome b, corresponding to approximately 1.2% sequen

157 This was thought to be mediated by duodenal cytochrome b (Cybrd1), a ferric reductase enzyme residen

158 Two mitochondrial genes, namely, cytochrome b (CYT B) and NADH dehydrogenase subunit 2 (N

159 ypeptide derived from the C-terminal half of cytochrome b (Cyt b) encoded by the mitochondrial genome

160 atin-induced apoptosis due to an increase of cytochrome b (Cyt b) expression and its release from mit

161 tive open reading frame of the mitochondrial cytochrome b (cyt b) gene in melanoma cells established

162 l DNA (mtDNA) cytochrome oxidase I (COI) and cytochrome b (Cyt b) gene markers, we inferred the origi

163 ts and newly designed from the mitochondrial cytochrome b (cyt b), cytochrome oxidase I (COI), and 12

164 ur DNA sequences were analysed-mitochondrial cytochrome b (cyt b), nuclear elongation factor-1alpha (

165 tutions in the atovaquone-binding regions of cytochrome b (cytb) and the azithromycin-binding region

166 Mitochondria-encoded Cytochrome B (CYTB) gene mutations were reported in diff

167 one, a ubiquinone analogue, targets C. felis cytochrome b (cytb), of which 30 unique genotypes have b

168 skippers based on three mitochondrial genes (cytochrome b (Cytb), the NADH dehydrogenase subunit 1 (N

169 ely cytochrome c oxidase subunit I (COI) and cytochrome b (cytb), were analysed in silico to identify

170 using mitochondrial genes, and in particular cytochrome b (cytb).

171 Species-specific primers were designed from cytochrome b, cytochrome oxidase I, and 16S rRNA genes t

172 etal transporter 1 (DMT1) 3.2-fold, duodenal cytochrome b (Dcytb) 1.8-fold, and transferrin receptor

173 ensitive than with a mitochondrial probe for cytochrome b despite higher copy numbers of mitochondria

174 Previous work has shown that, although cytochrome bd does not pump protons, turnover is coupled

175 Here, we establish a rate for cytochrome b evolution in avian malaria parasites relati

176 Respiratory chain complex III and possibly cytochrome b function are essential for this increase.

177 ected to an NGS approach targeting two short cytochrome b gene (cytb) fragments on the Illumina MiSeq

178 We characterized the C. felis cytochrome b gene (cytb) in cats with cytauxzoonosis and

179 Our research revealed that a mutation in the cytochrome b gene (G126S) in 35% tested T. urticae popul

180 We found that the parasite cytochrome b gene evolves about 60% as rapidly as that o

181 y applying a previously established parasite cytochrome b gene mutation rate (0.012 mutations per sit

182 A sequences of portions of the mitochondrial cytochrome b gene obtained from gorilla parasites closel

183 throughout Europe using 476-bp mitochondrial cytochrome b gene sequences.

184 ain reaction (PCR) (nested PCR targeting the cytochrome b gene) and quantitative PCR as reference sta

185 sing conserved regions of mitochondrial DNA (cytochrome b gene) was performed to evaluate the halal a

186 linked to the appearance of mutations in the cytochrome b gene.

187 e diversity in New World Myotis by analyzing cytochrome-b gene variation from an expansive sample ran

188 d targeting mitochondrial ND5, ATPase 6, and cytochrome b genes to amplify 172, 163, 141, 129 and 108

189 oth nuclear (MHC DRB) and mitochondrial DNA (cytochrome b) genes.

190 could distinguish C. felis cytb1 from other cytochrome b genotypes.

191 y using stopped flow, the reduction rates of cytochromes b(H) and c(1) were 403 s(-1) (t(1/2) 1.7 ms)

192 rane potential, and redox states of NADH and cytochromes b(H), b(L), c(1), c, and a,a(3)] were compar

193 introduction, we analyzed L. littorea, using cytochrome b haplotypes.

194 g two one-electron carriers, a low potential cytochrome b heme and the "Rieske" iron-sulfur cluster.

195 The cytochrome bd-I complex of Escherichia coli is a respira

196 Loss of the flavohemoglobin Hmp and cytochrome bd-I elicit the greatest sensitivity to NO-me

197 a mean of approximately 76, indicating that cytochrome bd-I is concentrated in mobile patches in the

198 uent catalytic steps of the Escherichia coli cytochrome bd-I oxidase were investigated by means of ul

199 YtfE), and the expression of the NO-tolerant cytochrome bd-I respiratory oxidase (CydAB).

200 echanisms to evade nitrosative stresses, the cytochrome bd-I respiratory oxidase is the main contribu

201 Intriguingly, the cytochrome bd-I respiratory oxidase was the only system

202 (YTL01) that expresses functional GFP-tagged cytochrome bd-I terminal oxidase complexes under wild-ty

203 The Salmonella cytochrome bd-II oxidase synergized with nitrate reducta

204 - intermediate, indicating a direct role for cytochrome b in O2*- generation.

205 s of our tests suggest that the evolution of cytochrome b in Peromyscus is chiefly governed by purify

206 saturation, indicating an indirect role for cytochrome b in the mediation of NO consumption.

207 Molecular analyses were applied to mtDNA cytochrome b, intron AM2B1 and 15 microsatellite loci.

208 We show that the reduction site of cytochrome b is also a druggable target.

209 Because cytochrome b is encoded by the maternally inherited para

210 in the mitochondrial inner membrane by which cytochrome b is hemylated.

211 bc(1) activity, indicating that the S322 of cytochrome b is important.

212 Our results show that cytochrome b is less variable than expected given the di

213 f quinol with oxygen that are observed after cytochrome b is reduced were unaffected by the E272Q sub

214 Cytochrome bd is a quinol oxidase from Escherichia coli,

215 Cytochrome bd is encoded by cydAB from the cydABDC gene

216 omplex has a dual function for biogenesis of cytochrome b: it is both required for efficient synthesi

217 mine the presteady-state kinetics of ISP and cytochrome b(L) reduction by ubiquinol.

218 otential inhibits electron transfer from the cytochrome b(L) to b(H) hemes, thereby promoting the for

219 milar reduction kinetic is also observed for cytochrome b(L), indicating a simultaneous reduction of

220 chrome b synthesis and thus reducing overall cytochrome b levels.

221 es that encode components of NADPH oxidases (cytochrome b light chain and encodes p22(phox) protein;

222 roduce hydrogen peroxide; instead, it uses a cytochrome b-like protein as an electron acceptor.

223 eals an operon (cydAB) apparently encoding a cytochrome bd-like oxidase homologous to oxidases in Esc

224 eric [NiFe]-hydrogenase that lacks a typical cytochrome b membrane anchor subunit, which transfers el

225 d with point mutations in the Q(o) pocket of cytochrome b, most notably near the conserved Pro(260)-G

226 dox potential of the FeS cluster, or a E272Q cytochrome b mutation, which eliminates the proton accep

227 II subunit Rieske iron sulfur protein in the cytochrome b-null cells and treatment of wild-type cells

228 In bacterial cytochrome b of the cytochrome bc(1) complex, there is a

229 Arg-94 in cytochrome b of the Rhodobacter sphaeroides bc(1) comple

230 gene markers, Cytochrome Oxidase I (COI) and Cytochrome b oxidase (COB), have been used to assess DNA

231 with data showing that CydX is required for cytochrome bd oxidase activity, copurification experimen

232 the naphthoquinones, which pass electrons to cytochrome bd oxidase and the anaerobic terminal reducta

233 around E. coli that identified high-affinity cytochrome bd oxidase as an essential bacterial gene pro

234 pothesis that CydX is a subunit of the CydAB cytochrome bd oxidase complex that is required for compl

235 indicate that CydX interacts with the CydAB cytochrome bd oxidase complex.

236 A M. tuberculosis cytochrome bd oxidase deletion mutant (DeltacydKO) was h

237 noculated with E. coli mutants defective for cytochrome bd oxidase did not.

238 Moreover, cytochrome bd oxidase expression increased, but cytochro

239 rose, E. coli became strictly dependent upon cytochrome bd oxidase for continued respiration.

240 e propose that the sulfide resistance of the cytochrome bd oxidase is a key trait that permits respir

241 Competitive colonizations revealed that cytochrome bd oxidase is more advantageous than nitrate

242 , we show that the electron flow through the cytochrome bd oxidase is sufficient to maintain respirat

243 Cytochrome bd oxidase operons from more than 50 species

244 production of reactive oxygen species by the cytochrome bd oxidase was below the detection level of 1

245 that the alternate terminal bd-type oxidase (cytochrome bd oxidase) is capable of maintaining a membr

246 In the absence of the back-up cytochrome bd oxidase, growth failed.

247 Mutants lacking the high-affinity cytochrome bd oxidase, which is used when oxygen tension

248 Upon genetic deletion of the cytochrome bd oxidase-encoding genes cydAB, Q203 inhibit

249 odes products required for the production of cytochrome bd oxidase.

250 The quinol-linked cytochrome bd oxidases are terminal oxidases in respirat

251 The cytochrome bd oxidases are terminal oxidases that are pr

252 Although cytochrome bd oxidases have been studied for more than 7

253 The results indicate that cytochrome bd oxidases like the heme-copper oxidases bre

254 However, in cytochrome bd oxidases, the fourth electron is donated b

255 The cytochrome b oxidation center is a validated antimalaria

256 n for 12s rRNA) in: third codon positions of cytochrome B, probably because, unlike rRNAs, specific m

257 Finally, homology models of the cytochrome b protein revealed a substitution in rutilus

258 dases (RTOs), cytochrome c oxidase (Cox) and cytochrome bd quinol oxidase (Cyd), are present in the p

259 The kinetics and extent of cytochrome b reduced by quinol in the presence of variab

260 Additionally, the extent of fast cytochrome b reduction by menaquinol through center N in

261 in a non-linear inhibition of the extent of cytochrome b reduction by quinol together with a shift o

262 sult in a linear inhibition of the extent of cytochrome b reduction through center N.

263 robe based on sequences of the mitochondrial cytochrome b region was designed.

264 different single amino acid substitutions in cytochrome b rendering the yeast resistant to the inhibi

265 l methods, i.e. Hake-ITS1-RFLP (89%) or Hake-Cytochrome b-RFLP (83%).

266 In vitro response and cytochrome b sequence did not indicate atovaquone resist

267 In vitro response to atovaquone and cytochrome b sequence of clinical isolates were determin

268 ern South China Seas using the mitochondrial cytochrome b sequences and Bayesian Skyline Plot analyse

269 Phylogenetic analysis of cytochrome b sequences derived from these subfossils cor

270 These new data (188 cytochrome b sequences) bring the total number of sequen

271 METHODOLOGY AND PRINCIPAL FINDINGS: Cytochrome-b sequences were generated and phylogenetical

272 s) were classified as Chlorocebus sabaeus by cytochrome b sequencing.

273 Failure to hemylate cytochrome b sequesters the Cbp3-Cbp6 complex in early a

274 erial system, we show that mutation G167P in cytochrome b shifts the equilibrium distribution of ISP-

275 The nucleotide sequence of cytochrome b showed extremely high utility for recent ep

276 he quinone when the Rieske protein is in the cytochrome b site, as the residue experiencing the remar

277 d between the hydroquinone and His154 at the cytochrome b site.

278 we show that a conserved Tyr residue of the cytochrome b subunit of cytochrome bc(1) is critical for

279 ia eutropha, including the membrane-integral cytochrome b subunit, was investigated electrochemically

280 tional repositioning of the cd1 helix in the cytochrome b subunit.

281 one center N can equilibrate between the two cytochrome b subunits of the bc(1) complex dimer.

282 ex, thereby making Cbp3-Cbp6 unavailable for cytochrome b synthesis and thus reducing overall cytochr

283 ntermediates, thereby causing a reduction in cytochrome b synthesis via a feedback loop that senses h

284 e, we report that Cbp3-Cbp6 also coordinates cytochrome b synthesis with bc(1) complex assembly.

285 acquisition that triggers the progression of cytochrome b through successive assembly intermediates.

286 shift of this helix modulates the ability of cytochrome b to bind ISP.

287 ochrome b were observed in 2 cases (ratio of cytochrome b to ND1: 0.80 [95% CI, 0.68-0.92] vs 0.99 [9

288 . monocytogenes has two terminal oxidases, a cytochrome bd-type (CydAB) and a cytochrome aa 3-type me

289 ases, an aa3-type cytochrome c oxidase and a cytochrome bd-type menaquinol oxidase.

290 In Escherichia coli, the biogenesis of both cytochrome bd-type quinol oxidases and periplasmic cytoc

291 e test for evidence of positive selection on cytochrome b variation within and among species of the e

292 Using cytochrome b variation, we characterized phylogenetic di

293 extraction of DNA, followed by nested PCR of cytochrome b, was the optimal strategy, allowing reliabl

294 munoreactivities of cytochrome oxidase 1 and cytochrome b were found in HD patients relative to contr

295 Deletions at the segment of cytochrome b were observed in 2 cases (ratio of cytochro

296 t cells deficient in the complex III subunit cytochrome b, which are respiratory incompetent, increas

297 Surprisingly, CcmF is a cytochrome b with a haem never before realized, and in v

298 volves interactions of the newly synthesized cytochrome b with assembly factors and structural comple

299 ) complex and its effect on the reduction of cytochrome b with center P blocked.

300 ts the catalytic quinol oxidation Qo site in cytochrome b with cytochrome c1.