ライフサイエンスコーパス: cytochrome c oxidase

1 by the binuclear heme a3/CuB active site of cytochrome c oxidase.

2 talation of the Cu(B) center of subunit 1 of cytochrome c oxidase.

3 a toxin at high concentrations and inhibits cytochrome c oxidase.

4 ansfer in the IMS and thus for biogenesis of cytochrome c oxidase.

5 p372 as the location of this site in the ba3 cytochrome c oxidase.

6 preformed stores and reduced deactivation by cytochrome c oxidase.

7 on, if any, of reduced deactivation of NO by cytochrome c oxidase.

8 A recent example is provided by studies of cytochrome c oxidase.

9 itochondrial matrix for eventual assembly of cytochrome c oxidase.

10 plays an important role in the formation of cytochrome c oxidase.

11 within different MRC components upstream of cytochrome c oxidase.

12 tory activity caused by diminished levels of cytochrome c oxidase.

13 ancer because of its action on mitochondrial cytochrome c oxidase.

14 e productive assembly of the subunits of the cytochrome c oxidase.

15 otoxic stress with a major contribution from cytochrome c oxidase.

16 d copper protein involved in the assembly of cytochrome c oxidase.

17 (2+) centres of soluble guanylate cyclase or cytochrome c oxidase.

18 m by association of the bc1 complex with the cytochrome c oxidase.

19 e a biosynthesis and/or transfer to maturing cytochrome c oxidase.

20 ation by potently inhibiting the heme-copper cytochrome c oxidase.

21 tner of Cox17 in transferring copper ions to cytochrome c oxidase.

22 a more specific defect of respiratory chain cytochrome-c oxidase.

23 unction in mitochondrial respiration through cytochrome-c oxidase.

24 tion into California using the mitochondrial cytochrome c oxidase 1 (CO1) gene.

25 ients with mutations in the two synthesis of cytochrome c oxidase 1 and 2 proteins (SCO1 and SCO2), e

26 Using human cells lacking Synthesis of Cytochrome c Oxidase 2 (SCO2-/-), we have tested the oxy

27 othesised a mechanistic relationship between cytochrome c oxidase activity and Cox7a1 protein levels

28 ction by measuring H2O2, lipid peroxidation, cytochrome c oxidase activity and mitochondrial ATP.

29 Loss of Blp decreases cytochrome c oxidase activity and uncouples oxidative ph

30 Cytochrome c oxidase activity assays verified this findi

31 tein, have approximately 50-70% reduction in cytochrome c oxidase activity in all tissues yet a parad

32 Methylene blue increased cytochrome c oxidase activity in the presence of hydroge

33 s occur in mild hypoxia, where mitochondrial cytochrome c oxidase activity is unimpaired, suggesting

34 In the absence of Cmc2, cytochrome c oxidase activity measured spectrophotometri

35 synthase activity was lower (P < 0.0001) and cytochrome c oxidase activity per Mt unit was higher (P

36 Cytochrome c oxidase activity was measured using a cytoc

37 Cytochrome c oxidase activity was significantly reduced

38 lls, for example, mitochondrial respiration, cytochrome c oxidase activity, and ATP production.

39 l density, mDNA/nDNA ratio), and functional (cytochrome c oxidase activity, ATP synthesis rate) marke

40 Total cytochrome c content, cytochrome c oxidase activity, citrate synthase activity

41 ned AMP-dependent kinase activation improved cytochrome c oxidase activity, rescued the motor phenoty

42 Cytochrome c oxidase activity, uncoupling protein 1 expr

43 and I, respectively, and consequently lacked cytochrome c oxidase activity.

44 ostasis protein influential in mitochondrial cytochrome c oxidase activity.

45 associated with a selective 65% reduction of cytochrome c oxidase activity.

46 hing cells for wild-type mtDNA and restoring cytochrome c oxidase activity.

47 itochondrial respiratory chain complex IV or cytochrome c oxidase activity.

48 he respiratory chain by up-regulation of the cytochrome c oxidase activity.

49 onditions some mature Cox2 is assembled into cytochrome c oxidase allowing weak respiratory growth.

50 enzyme, is well expressed in neurons rich in cytochrome c oxidase, an important enzyme of the energy-

51 o terminal respiratory oxidases, an aa3-type cytochrome c oxidase and a cytochrome bd-type menaquinol

52 tected the activity of mitochondrial enzymes cytochrome c oxidase and aconitase in differentiating NS

53 tected the activity of mitochondrial enzymes cytochrome c oxidase and aconitase.

54 ibits cellular respiration via NO binding to cytochrome c oxidase and confirm that the six-to-five-co

55 e bc1 complex in the absence of a functional cytochrome c oxidase and identify a supercomplex indepen

56 nd exhibited comparatively lower activity of cytochrome c oxidase and increased glucose uptake.

57 degradation of hypohemylated Cox1 subunit of cytochrome c oxidase and is active in cytochrome c oxida

58 pression of ATP synthase's catalytic domain, cytochrome c oxidase and its tyrosine phosphorylation, m

59 ochondrial copper metabolism and delivery to cytochrome c oxidase and mitochondrially localized CuZn-

60 Methylene blue's ability to increase cytochrome c oxidase and protect RGCs against these noxi

61 y of the copper-binding mitochondrial enzyme cytochrome c oxidase and reduced ATP levels, despite enh

62 al fragment of Rcf2 associate with monomeric cytochrome c oxidase and respiratory chain supercomplexe

63 mologue of Cmc1, whose function affects both cytochrome c oxidase and Sod1.

64 tochondrial fragmentation and a reduction of cytochrome c oxidase and succinate dehydrogenase activit

65 Activities of cytochrome c oxidase and succinate reductase were increa

66 pressions of mediators of energy metabolism (cytochrome c oxidase) and mediators of neuronal activity

67 in both respiratory function and activity of cytochrome c oxidase, and increased mitochondrial oxidat

68 Cox17, a protein involved in the assembly of cytochrome c oxidase, and the MICOS complex.

69 respiratory electron chain dependent on the cytochrome c oxidase, and this uncoupling induces the al

70 ease of the transcript abundance/activity of cytochrome-c-oxidase, and slower phycocyanin degradation

71 ated MT-CO2, the mtDNA-encoded subunit II of cytochrome c oxidase; and (3) reduced spare respiratory

72 Unlike cytochrome c oxidase, AOX is cyanide insensitive.

73 proximately 19% decrease, females only), and cytochrome C oxidase ( approximately 20% increase, femal

74 llary-to-fiber ratio ( approximately 78.8%), cytochrome-c oxidase ( approximately 35%), and activity

75 biochemical deconvolution cascade suggested cytochrome c oxidase as the potential target of IPE clas

76 rome c oxidase activity was measured using a cytochrome c oxidase assay kit to monitor the health of

77 The mitochondrial cytochrome c oxidase assembles in the inner membrane fro

78 The requirement for Cox20 in cytochrome c oxidase assembly and respiratory growth is

79 Our analyses show that Oms1 participates in cytochrome c oxidase assembly by stabilizing newly synth

80 present in the promoter of the mitochondrial cytochrome c oxidase assembly gene (SCO2), which is crit

81 dicate that KLF6-dependent regulation of the cytochrome c oxidase assembly gene is critical for maint

82 Here we isolate a cytochrome c oxidase assembly intermediate in preparator

83 ets, iron-sulfur cluster scaffold (ISCU) and cytochrome c oxidase assembly protein (COX10), decreased

84 -sulfur cluster scaffold homolog) and COX10 (cytochrome c oxidase assembly protein), two important fa

85 Cytochrome c oxidase assembly requires the synthesis of

86 of S1P with homomeric PHB2 is important for cytochrome-c oxidase assembly and mitochondrial respirat

87 chain 3 (LC3) associated with mitochondrial (cytochrome c oxidase), autophagosome (p62), and autolyso

88 The reaction of oxidized bovine cytochrome c oxidase (bCcO) with hydrogen peroxide (H(2)

89 cooperative but nonoverlapping functions in cytochrome c oxidase biogenesis.

90 the COX1 mRNA is coupled to the assembly of cytochrome c oxidase by a mechanism that involves Mss51.

91 The Rhodobacter capsulatus cbb(3)-type cytochrome c oxidase (cbb(3)-Cox) belongs to the heme-co

92 y, we analyzed Cu delivery to the cbb3 -type cytochrome c oxidase (cbb3 -Cox) of Rhodobacter capsulat

93 Clones deficient in cytochrome c oxidase (CCO(-)) were identified by histoch

94 res in the reduction of dioxygen to water by cytochrome c oxidase (CcO) are particularly important to

95 ransfers electrons from the bc(1) complex to cytochrome c oxidase (CcO) as part of the mitochondrial

96 nificantly attenuate the function of Shy1 in cytochrome c oxidase (CcO) biogenesis as seen with the h

97 Cytochrome c oxidase (CcO) catalyzes the reduction of ox

98 Stalled biogenesis of the mitochondrial cytochrome c oxidase (CcO) complex results in degradatio

99 by deficiency in the entirely mtDNA encoded cytochrome c oxidase (CCO) enzyme by histochemical and i

100 functional mimic of the mitochondrial enzyme cytochrome c oxidase (CcO) has been a long-term goal of

101 13-subunit integral membrane protein bovine cytochrome c oxidase (CcO) have been studied by differen

102 on of the electron transport chain component cytochrome c oxidase (CcO) in cancer progression.

103 Cytochrome c oxidase (CcO) is a transmembrane protein th

104 The synthesis of the heme a cofactor used in cytochrome c oxidase (CcO) is dependent on the sequentia

105 Cytochrome c Oxidase (CcO) is known to catalyze the redu

106 nresolved issues regarding proton pumping in cytochrome c oxidase (CcO) is the identity of the gating

107 Cytochrome c oxidase (CcO) is the last electron acceptor

108 is required for the insertion of Cu(B) into cytochrome c oxidase (CcO) of mitochondria and many bact

109 The enzyme cytochrome c oxidase (CcO) or complex IV (EC 1.9.3.1) is

110 tional analyses have shown that bovine heart cytochrome c oxidase (CcO) pumps protons electrostatical

111 Cytochrome c oxidase (CcO) reduces O(2) to water via a s

112 Cytochrome c oxidase (CcO) reduces oxygen to water and u

113 Proton pumping A-type cytochrome c oxidase (CcO) terminates the respiratory ch

114 Cytochrome c oxidase (CcO) uses the energy released by r

115 malfunction of multiple proteins, including cytochrome c oxidase (CcO), and Cu/Zn superoxide dismuta

116 Cytochrome c oxidase (CcO), known as complex IV of the e

117 Cytochrome c oxidase (CcO), the terminal enzyme in the e

118 Cytochrome c oxidase (CcO), the terminal enzyme in the m

119 T is assumed to rely on photon absorption by cytochrome c oxidase (CCO), the terminal enzyme in the m

120 Biogenesis of cytochrome c oxidase (CcO), the terminal enzyme of the m

121 Here, we show that cytochrome c oxidase (CcO), the terminal oxidase of the

122 A key enzyme in aerobic metabolism is cytochrome c oxidase (CcO), which catalyzes the reductio

123 ctor of the mitochondrial respiratory enzyme cytochrome c oxidase (CcO).

124 ycle family to inhibit a biomimetic model of cytochrome c oxidase (CcO).

125 phism fingerprinting of the protein-encoding cytochrome c oxidase ccoN gene.

126 presses mitochondrial function by inhibiting cytochrome-c oxidase (CcOX; complex IV).

127 otein synthesis but rather have a problem in cytochrome c oxidase complex (COX) assembly.

128 tein p27 (Ldp27) is a component of an active cytochrome c oxidase complex in Leishmania donovani and

129 Deficiencies of cytochrome c oxidase complex IV, which reduces O2 in mit

130 a mitochondrial gene coding for a subunit of cytochrome c oxidase complex.

131 x1, Cox2, and Cox3, comprise the core of the cytochrome c oxidase complex.

132 Hydrogen sulphide (H2S) blocks the cytochrome-c oxidase complex (COX), predicting the evolu

133 tide (reduced) dehydrogenase (complex I) and cytochrome c oxidase (complex IV) activity levels (immun

134 The formation of the mature cytochrome c oxidase (complex IV) involves the associati

135 particular the cytochrome bc1 (complex III)-cytochrome c oxidase (complex IV) supercomplex (termed I

136 he terminal enzyme of the respiratory chain, cytochrome c oxidase, consists of a hydrophobic reaction

137 Cytochrome c oxidase contributes to the transmembrane pr

138 ociated with electron and proton transfer in cytochrome c oxidase could, in principle, be used to dis

139 present study, we found that the decrease in cytochrome c oxidase (COX) activity was ascribable to a

140 alized respiratory terminal oxidases (RTOs), cytochrome c oxidase (Cox) and cytochrome bd quinol oxid

141 ant decrease in the level of fully assembled cytochrome c oxidase (COX) and in its activity, suggesti

142 l oxidases: the thylakoid membrane-localized cytochrome c oxidase (COX) and quinol oxidase (Cyd) and

143 eporter protein, mitochondrial activity with cytochrome c oxidase (COX) and succinate dehydrogenase (

144 Cytochrome c oxidase (COX) and succinate dehydrogenase (

145 , suggesting an involvement in the CRC, with cytochrome c oxidase (COX) as a relevant protein complex

146 itochondrial protein with essential roles in cytochrome c oxidase (COX) assembly and the regulation o

147 east Saccharomyces cerevisiae, mitochondrial cytochrome c oxidase (COX) biogenesis is translationally

148 -immunoprecipitation using antibodies to the cytochrome c oxidase (COX) complex, present in the inner

149 frequently associated with cardiomyopathy is cytochrome c oxidase (COX) deficiency caused by mutation

150 Cytochrome c oxidase (COX) deficiency is a frequent bioc

151 Accordingly, CO increased cytochrome c oxidase (COX) enzymatic specific activity a

152 itochondrial respiratory capacity due to low cytochrome c oxidase (COX) expression.

153 oxidase subunit 4 isoform 1 (Cox4i1) impair cytochrome C oxidase (COX) function, the multimeric enzy

154 -2-HG-mediated inhibition of the activity of cytochrome c oxidase (COX) in the mitochondrial electron

155 Cytochrome c oxidase (COX) is the terminal enzyme of the

156 Cytochrome c oxidase (COX) is the terminal enzyme of the

157 Cytochrome c oxidase (COX) or complex IV of the mitochon

158 of this pathway involves phosphorylation of cytochrome c oxidase (COX) subunit 4-isoform 1 (COX4i1),

159 ovel component of the yeast cytochrome bc(1)-cytochrome c oxidase (COX) supercomplex.

160 Cytochrome c oxidase (COX) was initially purified more t

161 oteins that are required for the assembly of cytochrome c oxidase (COX), a mitochondrial respiratory

162 Cytochrome c oxidase (COX), the last enzyme of the respi

163 Copper is required for the activity of cytochrome c oxidase (COX), the terminal electron-accept

164 Cytochrome c oxidase (COX), the terminal enzyme of the m

165 sed mitochondrial iron loading and levels of cytochrome c oxidase (COX), which led to mitochondrial d

166 isorders from a range of 'large' and 'small' cytochrome c oxidase (COX)-deficient regions in skeletal

167 Ragged-red and cytochrome c oxidase (COX)-negative fibers, together wit

168 mtDNA was analyzed from cytochrome c oxidase (COX)-positive and COX-negative are

169 add two copper ions to the catalytic core of cytochrome c oxidase (COX).

170 tes to fail in the assembly of mitochondrial cytochrome c oxidase (COX).

171 sembly and metalation of functionally active cytochrome c oxidase (COX).

172 Mitochondrial Complex IV [cytochrome c oxidase (COX)] deficiency is one of the mos

173 chondrial transcription factor A (T-fam) and cytochrome c oxidase (COX, complex IV).

174 Isolated cytochrome-c oxidase (COX) deficiency is one of the most

175 ults of histochemical analysis revealed that cytochrome-c oxidase (COX) deficiency was more evident i

176 mitochondrial respiratory chain complex IV (cytochrome c oxidase, COX).

177 The cytochrome c oxidase Cox2 has been purified from native

178 Cytochrome c oxidases (Coxs) are the basic energy transd

179 ol-cytochrome c reductase; cyt. bc1) and IV (cytochrome c oxidase; CytcO).

180 th MICOS disassembly, abnormal cristae, mild cytochrome c oxidase defect, and sensitivity to glucose

181 ndria and CMC2 expression knockdown produces cytochrome c oxidase deficiency in Caenorhabditis elegan

182 Muscle studies showed global cytochrome-c oxidase deficiency in all patients tested a

183 ndividuals with mitochondrial complex IV (or cytochrome c oxidase) deficiency have mutations in the b

184 Clonality was demonstrated by following cytochrome c oxidase-deficient (CCO(-)) cells that share

185 Cytochrome c oxidase-deficient (CCO(-)) metaplastic glan

186 tal muscle biopsies revealed the presence of cytochrome c oxidase-deficient fibres and multiple mitoc

187 ccumulation, mitochondrial proliferation and cytochrome c oxidase-deficient fibres, but no typical ra

188 colemmal accumulation of mitochondria and/or cytochrome c oxidase-deficient fibres.

189 However, the cytochrome c oxidase-deficient load was over four times

190 d inhibition are significantly attenuated in cytochrome c oxidase-deficient mice.

191 nit of cytochrome c oxidase and is active in cytochrome c oxidase-deficient mitochondria.

192 ions in individual muscle fibres with 20% of cytochrome c oxidase-deficient myofibres accumulating tw

193 Laser capture microdissection of cytochrome-c oxidase-deficient fibers revealed mitochond

194 tant lines impaired in the expression of the CYTOCHROME C OXIDASE DEFICIENT1 (COD1) gene, which encod

195 ble reduction of oxygen to bound peroxide at cytochrome c oxidase determining the net flux.

196 Fluorophore-labeled cytochrome c oxidase displayed a similar increase when r

197 The aa(3)-type cytochrome c oxidase from Rhodobacter sphaeroides utiliz

198 trochemical modulation has been performed on cytochrome c oxidase from Rhodobacter sphaeroides.

199 Proton transfer in cytochrome c oxidase from the cellular inside to the bin

200 Proton transfer in cytochrome c oxidase from the cellular inside to the bin

201 the kinetics of dioxygen reduction by ba(3) cytochrome c oxidase from Thermus thermophilus in the ab

202 The ba3-type cytochrome c oxidase from Thermus thermophilus is a memb

203 an 844 base pair region of the mitochondrial Cytochrome c oxidase gene, present at approximately 1 pp

204 elevated expression of several mitochondrial cytochrome C oxidase genes, suggesting increased aerobic

205 quone-sensitive) control strain in bc(1) and cytochrome c oxidase genes.

206 of proton translocation in these cbb(3)-type cytochrome c oxidases has remained controversial.

207 chondrial proliferation and total absence of cytochrome- c oxidase histochemical stain.

208 argeting short (127-314 bp) fragments of the cytochrome c oxidase I (CO1) DNA barcode region were dev

209 ochondrial DNA control region (mtDNA CR) and cytochrome c oxidase I (COI) gene from five populations

210 Here, metabarcoding of cytochrome c oxidase I (COI) region of mitochondrial DNA

211 uce DNA barcodes from the mitochondrial gene cytochrome c oxidase I (COI).

212 in expression of the mitochondrially encoded cytochrome C oxidase I (MTCO1), complex I activity, and

213 techniques based on two mitochondrial genes (cytochrome c oxidase I and 16S rRNA) we prove the existe

214 seq flowcell to obtain 658 base pairs of the cytochrome c oxidase I DNA barcode in 1,010 specimens fr

215 We sampled haplotypes of mitochondrial cytochrome c oxidase I from 28 Lepidoptera species and 1

216 is of sequence analysis of the mitochondrial cytochrome c oxidase I gene.

217 nd decreased levels of mitochondrial complex cytochrome c oxidase I/IV and lower ATP levels.

218 the available structures of ba(3)- and aa(3)-cytochrome c oxidases identifies possible active pathway

219 atomistic molecular dynamics simulations of cytochrome c oxidase in an explicit membrane-solvent env

220 binding of Na(+) and Ca(2+)cations to bovine cytochrome c oxidase in its fully oxidized and partially

221 Cytochrome c oxidase in the inner membrane of mitochondr

222 e a is an essential cofactor for function of cytochrome c oxidase in the mitochondrial electron trans

223 Deletion of subunit Va of cytochrome c oxidase, inhibition of F(1)F(0) adenosine t

224 on function (Q) of the redox center CuA from cytochrome c oxidase is attained by tuning the accessibi

225 on of the protonation rate at the surface of cytochrome c oxidase is found when the lipid area surrou

226 rmore, a reaction step that in the wild-type cytochrome c oxidase is linked to simultaneous proton up

227 The heme(a3)/Cu(B) active site of cytochrome c oxidase is responsible for cellular nitrite

228 The Cox2 subunit of Saccharomyces cerevisiae cytochrome c oxidase is synthesized in the mitochondrial

229 The O-->E intermediate of cytochrome c oxidase is the first redox state in its cat

230 Cytochrome c oxidase is the last respiratory complex of

231 sessment of mitochondrial content (mtDNA and cytochrome C oxidase IV [COXIV]), complete ((14)CO(2) pr

232 Mitochondrial cytochrome c oxidase-IV, ATP synthase-beta, and NADH deh

233 te (Cu(A)) on subunit II (CoxB) of bacterial cytochrome c oxidase lie on the periplasmic side of the

234 This approach identified cytochrome c oxidase (LmCOX) subunit IV as a LACK-depend

235 ession of mitochondrial-encoded subunit 1 of cytochrome c oxidase (MTCO1), a subunit of respiratory c

236 reduced forms are reported for two bacterial cytochrome c oxidase mutants that define the D and K pro

237 Muscle biopsies showed cytochrome c oxidase-negative fibers and mtDNA multiple

238 atients, muscle biopsy showed ragged-red and cytochrome c oxidase-negative fibres with combined respi

239 ies of specific membrane proteins, including cytochrome c oxidase, NhaA Na(+)/H(+) exchanger, ClC-7 H

240 Cytochrome c oxidases of facultative members of the comm

241 plex I (NADH:quinone oxidoreductase) and IV (cytochrome c oxidase) of this patient.

242 In cytochrome c oxidase, one such pathway starts near a con

243 ong with a correlation between the number of cytochrome c oxidase operons and heterotrophic or diazot

244 Defects in mitochondrial cytochrome c oxidase or respiratory chain complex IV (CI

245 the oxidation state of mitochondrial enzyme cytochrome-c-oxidase (oxCCO) have the potential to yield

246 impressive results, a model of mitochondrial cytochrome c oxidase polypeptide I was obtained with a T

247 uptake in the Asn-139-Thr/Asp-132-Asn mutant cytochrome c oxidase, proton pumping was impaired, which

248 Cytochrome c oxidase reduces O(2) to H(2)O, a reaction c

249 e to Zn(2+) addition, which in the wild-type cytochrome c oxidase slows the reaction, indicating that

250 We developed specific primers for the cytochrome c oxidase subunit 1 (cox1) gene of bdelloid r

251 unravel the use of the mitochondrial marker cytochrome c oxidase subunit 1 (coxI) as barcode for Lon

252 mitochondrial fraction indicates binding of cytochrome c oxidase subunit 1 (mt-COX1) mRNA from the m

253 in a stretch of 22 identical amino acids in cytochrome c oxidase subunit 1 and NADH dehydrogenase su

254 e KRIPP1 knockdown, A/U-tailed mRNA encoding cytochrome c oxidase subunit 1 declined concomitantly wi

255 uberculosis, a sequence in the mitochondrial cytochrome C oxidase subunit 1 gene of nematodes and the

256 nal assays, CB9032258 restored mitochondrial cytochrome c oxidase subunit 1 levels and rescued impair

257 of apoE4, including decreased mitochondrial cytochrome c oxidase subunit 1 levels, reduced mitochond

258 The region of the mitochondrial cytochrome c oxidase subunit 1 used as the animal barcod

259 EIL2 with the mitochondrion-specific protein cytochrome c oxidase subunit 2 (MT-CO2).

260 h the mitochondrial genes MT-CO2 and MT-CO3 (cytochrome c oxidase subunit 3); importantly, both enzym

261 voltage-dependent anion channel (VDAC), and cytochrome c oxidase subunit 4 (COX IV).

262 he assembly of nuclear-encoded subunits like cytochrome c oxidase subunit 4 (Cox4) into the mature co

263 ow that the mitochondrial complex IV subunit cytochrome C oxidase subunit 4 (Cox4i1) is a direct TAp7

264 Specifically, decreased levels of cytochrome C oxidase subunit 4 isoform 1 (Cox4i1) impair

265 was to analyze the function of lung-specific cytochrome c oxidase subunit 4 isoform 2 (COX4i2) in vit

266 d recently by our laboratory to regulate all cytochrome c oxidase subunit genes and some NMDA and AMP

267 Two DNA barcode regions, namely cytochrome c oxidase subunit I (COI) and cytochrome b (c

268 Drosophila, mt:CoI(T300I), which affects the cytochrome c oxidase subunit I (CoI) locus.

269 S and of the main alternatively used marker [Cytochrome c oxidase subunit I (COI) mtDNA] belonging to

270 equence of the "DNA barcoding" region of the cytochrome c oxidase subunit I (COI).

271 sed on a single mitochondrial locus, such as cytochrome c oxidase subunit I (COI).

272 in the mtDNA [NADH dehydrogenase 6 (ND6) and cytochrome c oxidase subunit I (COI)] or nuclear DNA [ad

273 rtial sequence for the mitochondrial-encoded cytochrome c oxidase subunit I (Cox 1) gene in the cell

274 chondrial transcription factor-1 (Tfam), and cytochrome c oxidase subunit I (Cox-1) was determined by

275 de diversity (pi) for the mitochondrial gene cytochrome c oxidase subunit I (cox1).

276 swarms by sequencing 1173 bases of the gene cytochrome c oxidase subunit I (cox1, COI) from 504 indi

277 translation-competent, long poly(AU)-tailed cytochrome c oxidase subunit I and edited apocytochrome

278 tures) over a 6-mo period were identified by cytochrome c oxidase subunit I barcoding (>2-mm mobile o

279 We examined Cytochrome c oxidase subunit I haplotypes from introduce

280 preferential inhibition of synthesis of the cytochrome c oxidase subunit I over apocytochrome b were

281 For the second objective, mitochondrial cytochrome c oxidase subunit I sequences of 16 individua

282 Pyrosequencing of genetic marker, COI (cytochrome c oxidase subunit I) and subsequent sequence

283 ing human immunoglobulin lambda locus (IGL), cytochrome c oxidase subunit II (COX2), Golgi-associated

284 ted, and the norE product is a member of the cytochrome c oxidase subunit III family.

285 The cytochrome c oxidase subunit isoform Cox7a1 is highly ab

286 d transcription of the mtDNA encoded protein cytochrome c oxidase subunit-I (COI).

287 ption-factor-A (TFAM), mitochondrial-protein-cytochrome-C-oxidase subunit-2 (COX2), sirtuin-1 (SIRT1)

288 ntially affected, with near normal levels of cytochrome c oxidase subunit2 and Nad7 but little Nad6 p

289 ichiometric imbalance between mitochondrial (cytochrome c oxidase subunits 1 and 2) and nuclear (succ

290 pecies, respiratory dysfunction, and loss of cytochrome c oxidase subunits and activity.

291 A key component of such metabolism is cytochrome c oxidase, the 13-subunit terminal complex of

292 Conditional deletion of cytochrome c oxidase, the terminal enzyme in the respira

293 t the unusual sensitivity of skeletal muscle cytochrome c oxidase to sulfide poisoning in ethylmaloni

294 xidative phosphorylation while also exposing cytochrome c oxidase to this metabolic poison.

295 plex followed by cytochrome c oxidation by a cytochrome c oxidase, ubiquinol oxidation by Cox2 is of

296 nstant approximately 65 mus in the wild-type cytochrome c oxidase) was impaired in the Asp372Ile vari

297 , whereas mice deficient in the synthesis of cytochrome c oxidase, which have reduced COX, were prote

298 3) pharmacologic and genetic manipulation of cytochrome c oxidase, which restores sensitivity to TMZ-

299 cbb3-type cytochrome c oxidases, which catalyze the terminal step

300 OX5b-1 gene, which encodes an isoform of the cytochrome c oxidase zinc binding subunit.