ライフサイエンスコーパス: cytochrome c'

1 in the presence of NADPH by cell-free assay (cytochrome c).

2 itin, eglin c, ribonuclease A, lysozyme, and cytochrome c).

3 a number of heme protein systems, including cytochromes c'.

4 We study a protein (horse cytochrome c, 104 amino acids) whose fluorescence increa

5 c, as compared with those with nondetectable cytochrome c (11% versus 1%; P<0.001).

6 with decreasing protein molecular mass: for cytochrome c (12.3 kDa) and lysozyme (14.3 kDa) a detect

7 (PNA) can be used to control the assembly of cytochrome c (12.5 kDa, pI 10.5) and azurin (13.9 kDa, p

8 exhibited significant rates of reduction of cytochrome c (160 min(-1), largely superoxide dismutase-

9 efficiently as wild type MSR but the rate of cytochrome c, 2,6-dichloroindophenol, and menadione redu

10 l mortality than patients with nondetectable cytochrome c (6% versus 1%; P<0.001).

11 isotopes at the fundamental distribution of cytochrome c(+8) (m/z approximately 1549) were nearly ba

12 by DESI-MS, were 100% for melittin, 100% for cytochrome c, 90% for myoglobin, and 65% for bovine seru

13 properties are reminiscent of the A-state of cytochrome c, a compact denatured form found under acidi

14 fic ablation of the proapoptotic function of cytochrome c, a key regulator of mitochondria-mediated a

15 ress-triggered changes in the translation of cytochrome c, a pivotal regulator of apoptosis.

16 hondrial function and reduces the release of cytochrome c, a pro-apoptotic cell death factor.

17 lso propose an orientation of membrane-bound cytochrome c, a protein for which the membrane orientati

18 SRCD measurements of the folding kinetics of cytochrome c, a small, fast-folding protein.

19 om proteins; a deamidated tryptic peptide of cytochrome c, a tryptic peptide from unfolded and deamid

20 mitochondrial membrane potential, release of cytochrome c, activation of Bax and Bak, and processing

21 grity of mitochondria, leading to release of cytochrome c, activation of caspase-3 and eventually exe

22 Ad-MMP-9 infection induced the release of cytochrome c, activation of caspase-9 and -3, and cleava

23 mitochondrial permeability shift, release of cytochrome c, activation of caspases, and subsequent fra

24 res contained four basic proteins (lysozyme, cytochrome c, alpha-chymotrypsinogen A, and ribonuclease

25 Release of cytochrome c, an activator of caspase-9, from mitochondr

26 Cytochrome c, an essential electron carrier in mitochond

27 (flavoprotein, succinate dehydrogenase, and cytochrome c) and the synthesis and activity of key deni

28 depolarizes mitochondria membranes, releases cytochrome c, and activates caspases-9 and -3 and death

29 hondrial membrane depolarization, release of cytochrome c, and activation of both intrinsic and extri

30 mitochondrial membrane potential, release of cytochrome c, and activation of caspase-3.

31 tial within 30 min, release of mitochondrial cytochrome c, and activation of caspase-activated DNase

32 chondrial proteins, release of the apoptogen cytochrome c, and activation of executioner caspase-3 we

33 islets was strongly correlated with reduced cytochrome c, and agents that acutely and specifically r

34 he release of Smac, Omi, adenylate kinase-2, cytochrome c, and apoptosis-inducing factor (AIF) during

35 ized HAzPC associated with mitochondria, and cytochrome c, and apoptosis-inducing factor escaped from

36 ial membrane potential, cytosolic release of cytochrome c, and apoptosis.

37 Using myoglobin, cytochrome c, and beta-2-microglobulin as model protein

38 ic protein, thyroglobulin, histone, insulin, cytochrome C, and beta-galactosidase.

39 formed in ESI for three proteins (ubiquitin, cytochrome c, and carbonic anhydrase II) were investigat

40 horylation of Bcl-2, expression of cytosolic cytochrome c, and caspase 3 activity.

41 Bax expression, a disturbed distribution of cytochrome c, and cleaved caspase-3 positive staining in

42 e purification of the engineered peroxidase, cytochrome c, and covalent complex, along with activity

43 how a reduction of mitochondrial components, cytochrome c, and cytochrome b.

44 aspase-8, deficient release of mitochondrial cytochrome c, and delayed activation of both caspase-9 a

45 duced unfolding of SNase, from acid-unfolded cytochrome c, and from folding of Azoarcus ribozyme.

46 in blocking apoptosis by reduction of ferric cytochrome c, and gentle tuning of NO concentration in t

47 CRALBP, cytochrome C, and GNB3 showed that the RPE interdigitati

48 enzymatic activity and immunoreactivity for cytochrome c, and identical functional properties shared

49 ious Mossbauer investigations on a bacterial cytochrome c, and is not reproduced by the simulations.

50 of the mass spectral response for myoglobin, cytochrome c, and lysozyme is presented for laser electr

51 apped, translated into a solution containing cytochrome c, and monitored for 3-NBS leakage.

52 and release of mitochondrial release of AIF, cytochrome c, and Smac induced by UVB.

53 as well as mitochondrial release of AIF and cytochrome c, and subsequent activation of caspase-9 in

54 on of the effector caspase-9, independent of cytochrome c, and subsequently the processing of the exe

55 mitochondrial truncated Bid, the release of cytochrome c, and the activation of caspase-3, thereby c

56 f caspases, apoptogenic mitochondrial factor cytochrome c, and the Bcl-2 family proteins in DR6-induc

57 R) in portal blood, the release of cytosolic cytochrome c, and the cleaved caspase 9 expression in in

58 cular, appeared to be restricted to nitrated cytochrome c, and thus, no association of non-nitrated c

59 elease, lipid peroxidation, translocation of cytochrome c, and TUNEL labeling in the ischemic cortex.

60 Proteins carbonic anhydrase, cytochrome c, and ubiquitin were used to demonstrate the

61 esults constitute the molecular mechanism of cytochrome c- and dATP-mediated activation of Apaf-1.

62 2 positions (C(18:2)/C(18:2)), formed in the cytochrome c- and H(2)O(2)-driven enzymatic oxidation re

63 acid-binding protein, myoglobin and somatic cytochrome-C) and others (creatine kinase M, malate dehy

64 e myocardial levels of lipid hydroperoxides, cytochrome-c, and mitochondrial aconitase activity were

65 ns c-Jun N-terminal kinase 3, caspase 3, and cytochrome C, Annexin V staining, RNA degradation, and o

66 tryptophans in three well-studied proteins, cytochrome c, apomyoglobin, and lysozyme, as a function

67 her a caspase-dependent mechanism, involving cytochrome c, apoptosis protease-activating factor-1 (Ap

68 avage; and Bcl-2 phosphorylation, as well as cytochrome c, apoptosis-inducing factor (AIF), and endon

69 The release of the apoptogenic factors cytochrome c, apoptosis-inducing factor (AIF), and proin

70 D ( approximately 16% decrease, males only), cytochrome C ( approximately 19% decrease, females only)

71 ase of intermembrane space proteins, such as cytochrome c, are early events during intrinsic (mitocho

72 Apoptotic factors, including cytochrome c, are released through these pores from the

73 Cytochromes c' are pentacoordinate heme proteins with st

74 a picosecond timescale for the heme protein, cytochrome c, as a function of oxidation and hydration,

75 gment-elevation AMI patients with detectable cytochrome c, as compared with those with nondetectable

76 s approach to the absolute quantification of cytochrome C (as target compound) in a commercial protei

77 terial heme protein Alcaligenes xylosoxidans cytochrome c' (AXCP) forms a novel five-coordinate heme-

78 between Fe2S2- (adrenodoxin-like) and heme- (cytochrome c) binding domains.

79 % (w/v) bovine serum albumin and 0.01% (w/v) cytochrome C (both are proteins), and 0.002% (w/v) human

80 ation and identification of proteins such as cytochrome c, bovine serum albumin, and high-molecular w

81 brane pores large enough to release not only cytochrome c, but also allophycocyanine, a protein of 10

82 erobic electron acceptors include oxygen and cytochrome c, but an acceptor that can function under an

83 electrons coming from NADH and ubiquinol to cytochrome c, but it is also capable of producing signif

84 sequent release of the mitochondrial protein cytochrome c, but the second mitochondrion-derived activ

85 Here, we identify a dihaem cytochrome c (C8j_0815; TsdA) as the enzyme responsible.

86 a result, during steady-state turnover with cytochrome c, calmodulin now deactivates the enzyme and

87 induced mitochondrial trafficking of Bax and cytochrome c, caspase-3 activation, and oxidative stress

88 he product of the enzymatic reaction reduces cytochrome c, causing an increase in absorbance at 550 n

89 (CcP)], suggesting both ascorbate (Asc) and cytochrome c (Cc) peroxidase activity.

90 Cytochrome c (CC)-initiated Apaf-1 apoptosome formation

91 Cytochrome c (CcP) and ascorbate peroxidase (APX) are he

92 s to the periplasmic enzymes that reduce apo-cytochrome c (CcsX) or repair oxidative protein damages

93 H2O2-dependent apoptosis in mouse embryonic cytochrome c(+/+) cells than in cytochrome c(-/-) cells.

94 se embryonic cytochrome c(+/+) cells than in cytochrome c(-/-) cells.

95 Both channel activities are modified by cytochrome c, consistent with entrance of this protein i

96 ria differed primarily at a Raman biomarker, cytochrome c, corresponding to a bacteroid-specific term

97 arkers of WAT mitochondrial protein content (cytochrome c, COXIV-subunit I, and citrate synthase acti

98 Biomolecule cytochrome c (Cty c), a small molecule of a chain of ami

99 Cytochrome c (CYC) oxidase (COX), a multisubunit enzyme

100 and the nuclear-encoded subunits of COX and cytochrome c (CYC), we hypothesized that some codons in

101 lus fumigatus alternative oxidase (aoxA) and cytochrome C (cycA) null mutants and assessed their abil

102 rving as respiratory electron shuttle, ferri-cytochrome c (cyt c) acts as a peroxidase; i.e., it cata

103 ns and ER stress as shown by increased HSP60/Cytochrome C (Cyt C) and CHOP-ATF3 levels respectively.

104 d, catalytic circuit based on photosystem I, cytochrome c (cyt c) and human sulfite oxidase (hSOX).

105 An axial S(Met) bond is also present in cytochrome c (cyt c) and is generally thought to increas

106 tive stress sensor contains the heme protein cytochrome c (cyt c) as sensing element whose spectral r

107 Cytochrome c (cyt c) binds to and penetrates lipid struc

108 tivation of peroxidase catalytic function of cytochrome c (cyt c) by anionic lipids is associated wit

109 y to investigate the early folding states of Cytochrome c (cyt c) by monitoring the distance between

110 ted for the first time that the heme protein cytochrome c (Cyt c) can enter the interior of a MOF des

111 The active site of cytochrome c (Cyt c) consists of a heme covalently linke

112 cribe advancements in sensing technology for cytochrome c (cyt c) detection, at point-of-care (POC) a

113 Proteins in the cytochrome c (cyt c) family with His-Met heme axial liga

114 alent mechanisms, are employed to immobilize cytochrome c (cyt c) for electrochemical analysis.

115 The release of cytochrome c (cyt c) from mitochondria is an important e

116 denatured states and the native structure of cytochrome c (Cyt c) from Saccharomyces cerevisiae.

117 activation is accompanied by the release of cytochrome c (cyt c) from the intermembrane gap and subs

118 Native cytochrome c (cyt c) has a compact tertiary structure wi

119 Horse heart cytochrome c (cyt c) has emerged as a paradigm for the s

120 Mammalian cytochrome c (Cyt c) has two primary functions: transfer

121 CRALBP and cytochrome C (Cyt C) immunolabeling revealed that hyperr

122 competent peroxidase form of pentacoordinate cytochrome c (cyt c) in a complex with a mitochondria-sp

123 vine serum albumin (BSA), lysozyme (lyz) and cytochrome c (cyt c) in singular and competitive manner

124 of Thr78Cys/Lys79Gly/Met80X mutants of yeast cytochrome c (cyt c) in which Cys78 becomes one of the a

125 It is well known that cytochrome c (Cyt c) is a crucial death regulator that t

126 Cytochrome c (cyt c) is a heme-containing protein that p

127 Cytochrome c (cyt c) is a small soluble heme protein cha

128 Cytochrome c (Cyt c) is an apoptosis-initiating protein

129 Cytochrome c (Cyt c) is an important biomarker in cell l

130 Cytochrome c (Cyt c) is commonly used as intrinsic bioma

131 Although the primary function of cytochrome c (cyt c) is electron transfer, the protein c

132 Cytochrome c (cyt c) is one of the most widely studied b

133 During apoptosis, cytochrome c (cyt c) is released from intermembrane spac

134 arly mitochondria-specific cardiolipin (CL), cytochrome c (cyt c) loses its tertiary structure and it

135 cytochrome c synthase (HCCS) is required for cytochrome c (cyt c) maturation and therefore respiratio

136 n one-shot adsorption of chemically-modified cytochrome c (cyt c) onto bare gold electrodes.

137 ies designed to investigate the integrity of cytochrome c (cyt c) photo-cross-linked via MPE.

138 tion of cardiolipin (CL) by its complex with cytochrome c (cyt c) plays a crucial role in triggering

139 The multifunctional protein cytochrome c (cyt c) plays key roles in electron transpo

140 has been suggested that the alkaline form of cytochrome c (cyt c) regulates function of this protein

141 tic stress induces apoptosis, which involves cytochrome c (Cyt c) release from mitochondria and subse

142 Cytochrome c (cyt c) release from mitochondria is accept

143 Cytochrome c (cyt c) release upon oxidation of cardiolip

144 s of the spontaneous reversible unfolding of Cytochrome c (Cyt c) under native conditions have led to

145 dy the reversible unfolding and refolding of cytochrome c (Cyt c) under native conditions.

146 Using a collection of dye-labeled cytochrome c (cyt c) variants, we identify transformatio

147 Cytoplasmic cytochrome c (cyt c) was released early in both cases, b

148 Interactions of cytochrome c (cyt c) with cardiolipin (CL) are important

149 Interactions of cytochrome c (cyt c) with cardiolipin (CL) partially unf

150 interaction of the simple, globular protein cytochrome C (Cyt C) with MPMN surfaces using experiment

151 rochemical immunosensor for the detection of cytochrome c (cyt c), a heme containing metalloprotein u

152 Cytochrome c (cyt c), a mitochondrial intermembrane elec

153 Bad dephosphorylation, increased cytoplasmic cytochrome c (cyt c), and RGC death.

154 Globular proteins, such as cytochrome c (cyt c), display an organized native confor

155 Cytochrome c (cyt c), required for electron transport in

156 nsfer reorganization free energy (lambda) of cytochrome c (Cyt) in electrostatic complexes that mimic

157 Various standard proteins (e.g. cytochrome C (Cyt-C), myoglobin (MYO) and bovine serum a

158 re is also a required role for mitochondrial cytochrome c (cyt-c).

159 Cytochrome c' (Cyt c') is a c-type cytochrome with a pen

160 hieved using redox cofactors namely oxidized cytochrome-c (Cyt-c) and Co-enzyme-Q (Co-Q) immobilized

161 The mesh is functionalized with cytochrome-c (cyt-c) and incorporated as a working elect

162 We have demonstrated that a protein (cytochrome c (Cytc c) or bovine serum albumin (BSA)) can

163 as an oligopeptide stopper, we have employed cytochrome C (CytC) as a protein stopper to produce the

164 oxygen to water, the one-electron reductant Cytochrome c (Cytc) being the source of electrons.

165 Monolayers of the redox protein Cytochrome C (CytC) can be electrostatically formed on a

166 The combined use of cytochrome c (CYTc) loss-of-function mutants and respira

167 r the directed immobilization of horse heart cytochrome c (cytc) on gold electrode surfaces to achiev

168 tion (MOMP) via BAK and BAX oligomerization, cytochrome c (cytc) release, and caspase activation are

169 Mammalian cytochrome c (Cytc) transfers electrons from the bc(1) c

170 -phycoerythrin (R-PE) and positively charged cytochrome c (CYTC) within the same DFGF apparatus is sh

171 te ETp across the electron-mediating protein cytochrome c (CytC), measured in a monolayer configurati

172 with alpha-chymotrypsin (ChT), histone, and cytochrome c (CytC).

173 rom mitochondria inhibited BAK/BAX-dependent cytochrome c (cyto c) release.

174 rate synthase), and the expression levels of cytochrome c, cytochrome c oxidase subunit 1, and mitoch

175 + H2O) with electrons donated by periplasmic cytochrome c (cytochrome c-dependent NO reductase; cNOR)

176 hibitor, prevented the increase in cytosolic cytochrome c, decreased caspase-3 activation, and partia

177 , exercise-induced increases in the mRNAs of cytochrome c, delta-aminolevulinate synthase, and citrat

178 polarization of mitochondria, and release of cytochrome c, demonstrating its important role as an ant

179 The diheme cytochrome c (DHC) from Rhodobacter sphaeroides is a sol

180 es for all three monomeric proteins, and for cytochrome c, dimers of significant intensity are also o

181 in an observed sequence coverage of 79% for cytochrome C (eight peptides), 47% for beta-lactoglobuli

182 hampers mitochondrial respiration, releases cytochrome c, elevates mitochondrial lipid peroxidation,

183 ectron transfer-triggered folding of reduced cytochrome c, far-UV time-resolved circular dichroism (T

184 65 mM SDS to induce the MG state in oxidized cytochrome c, folding of redcyt c was triggered with fas

185 f a relatively low molecular weight protein, cytochrome-c, for ESI-MS detection.

186 -coordinate heme-nitrosyl complex (5c-NO) of cytochrome c' from Alcaligenes xylosoxidans (AXCP) in wh

187 either heme face exists, as in the microbial cytochrome c' from Alcaligenes xylosoxidans (AxCYTcp), w

188 The five-coordinate NO-bound heme in cytochrome c' from an overexpressing variant of denitrif

189 tured state of a class II c-type cytochrome, cytochrome c' from Rhodopseudomonas palustris.

190 Examples include cytochrome c, green fluorescent protein, Mito-Tracker Re

191 re reveals a core that is typical of class I cytochromes c, having alpha-helices folded into a compac

192 using solutions of 1pmol/mul angiotensin II, cytochrome c, hemoglobin, and beta-casein.

193 -Volmer quenching constants (Ksv) for hemin, cytochrome c, hemoglobin, and myoglobin were 5.6x10(7),

194 ta defensin 1, truncated human lymphotactin, Cytochrome C, holo hemoglobin-alpha, ovalbumin, human tr

195 ged: the first was to maintain the KD of the cytochrome c' in the 1 microM range, and the second was

196 The association with nitrated cytochrome c, in particular, appeared to be restricted t

197 n conformations of a small globular protein, cytochrome c, in the presence of guanidine hydrochloride

198 d had greater amounts of cytosolic mtDNA and cytochrome c, increased apoptosis, and more IL-1beta sec

199 eased activation of caspase-3 and release of cytochrome c, indicating that a mitochondrial pathway wa

200 lding proteins, including alpha-lactalbumin, cytochrome c, intestinal fatty acid binding protein (IFA

201 Cytochrome c' is a heme protein from a denitrifying vari

202 wnstream of the mitochondria, with cytosolic cytochrome c, kills brain tumor cells but not normal bra

203 nents abolishes the ability of cells to form cytochrome c, leading in the case of Rhodobacter capsula

204 agonist could be shown to induce release of cytochrome c, leading to activation of caspase 9.

205 mP in a complex with its substrate, L. major cytochrome c (LmCytc) to 1.84 A, and compared the struct

206 PDGF, but not cytochrome C, localized at a protrusion tip induced a co

207 volves mitochondria, indicated by release of cytochrome c, loss of mitochondrial membrane potential a

208 ss of bovine thrombin, bovine serum albumin, cytochrome C, lysozyme and myoglobin.

209 ion to peptides, gas-phase HDX of ubiquitin, cytochrome c, lysozyme, and apomyoglobin were examined.

210 The glycated species of cytochrome C, lysozyme, and beta-casein formed during gl

211 Five proteins (ribonuclease A, cytochrome c, lysozyme, myoglobin, bovine serum albumin)

212 Cytochrome c [M + 5H](5+) ions present in one conformer

213 (NANOG, MYOD), antibodies, native proteins (cytochrome C), magnetic nanoparticles (MNPs), and nuclei

214 We show that as neurons mature, cytochrome c- mediated apoptosis progresses from inhibit

215 horylation and fatty acid oxidation, such as cytochrome c, medium-chain acyl-CoA dehydrogenase, and a

216 Mitochondrial biogenic (cytochrome c, mitochondrial transcription factor A), mor

217 dione or benzoquinone and weak activity with cytochrome c, molecular oxygen, and 5,5'-dithio-bis-2-ni

218 releases of a small protein (8 muL of 5 muM cytochrome-c, molecular mass ~12 kDa) and exhibits ~1 mi

219 digestion of four model proteins: melittin, cytochrome c, myoglobin, and bovine serum albumin.

220 The cytochrome c, myoglobin, and IFABP systems each had high

221 Good-quality ESI-MS spectra of cytochrome c, myoglobin, and lysozyme as test proteins i

222 A mixture containing four model proteins (cytochrome c, myoglobin, bovine serum albumin (BSA), and

223 the transport of electrons from ubiquinol to cytochrome c (or alternate physiological acceptors), yet

224 V(max) of each in four assays: reduction of cytochrome c, oxidation of NADPH, 17alpha-hydroxylase ac

225 Compared with reduced cytochrome c, oxidized cytochrome c binds to tRNA with a

226 opulations specific for the model Ags pigeon cytochrome c (PCC) and hen egg lysozyme (HEL).

227 tra of the B-bands of bovine and horse heart cytochrome c (pH 7.0) exhibit a pronounced couplet that

228 tensity caused by the alkaline transition of cytochrome c (pH 7.0-9.5), and (ii) an increase in inten

229 , Apaf-1, procaspase-9, procaspase-3, Hsp70, cytochrome c, PHAPI, CAS, and regulatory compounds to mi

230 -to-Bcl-2 ratio (R(2) = 0.83) and release of cytochrome c (R(2) = 0.92), but preceded in time the cas

231 The folding of reduced cytochrome c (redcyt c) is increasingly being recognized

232 old on a sub-millisecond time scale, whereas cytochrome c' refolding requires 10 s or more to complet

233 Third, cytochrome c, released from mitochondria early in apopto

234 d to be 350 and 25 mg/ml for rusticyanin and cytochrome c, respectively; cytochrome a was present as

235 energized complex II and transferred them to cytochrome c, restoring ATP biosynthesis rates.

236 atalytic amounts of cytochrome c oxidase and cytochrome c, results in ISP reduction.

237 the refolding of Rhodopseudomonas palustris cytochrome c' reveals dramatic differences between two v

238 -based apoptotic pathway involved release of cytochrome c, second mitochondria-derived activator of c

239 The heme meso protons of cytochrome c' showed a contact interaction that implied

240 -cytochrome c and Rhodopseudomonas palustris cytochrome c', shows that foldable sequences deviate sig

241 anied by mitochondrial injury and release of cytochrome c, Smac, and AIF into the cytosol and caspase

242 Bax:Bcl-2 ratio and mitochondrial release of cytochrome c, Smac, and AIF.

243 ease efficiency for the apoptogenic proteins cytochrome c, Smac, and HtrA2 in response to Bim.

244 caspase-independent, simultaneous release of cytochrome c, Smac, Omi, and adenylate kinase-2.

245 pathological changes and increased levels of cytochrome c, Smac/DIABLO and AIF in the cytosol while t

246 ay, leading to increased cytosolic levels of cytochrome c, Smac/Diablo and Omi/HtrA2, and activation

247 embrane potential, attenuated the release of cytochrome c, Smac/DIABLO, and apoptosis inducing factor

248 mitochondrial depolarization and release of cytochrome c, Smac/DIABLO, and apoptosis-inducing factor

249 e swelling was accompanied by the release of cytochrome c, Smac/DIABLO, Omi/HtrA2, and AIF but not en

250 The protein expressions of mitochondrial cytochrome c, stromal cell-derived factor-1, C-X-C chemo

251 ebrovascular mitochondria, such as ER-alpha, cytochrome c, subunit IV of complex IV, and manganese su

252 n transferase activity with equine and yeast cytochrome c, suggesting a conservation of the enzymatic

253 Apaf-1 and rendered the cells insensitive to cytochrome c, suggesting a potential role for Rsk signal

254 th released the apoptogenic factors Smac and cytochrome c, suggesting that they are primed for cell d

255 o affect the buried hydrogen bond network of cytochrome c, suggesting that this network is an importa

256 While the N-terminal domain is a class I cytochrome c, the C-terminal domain shows no similarity

257 ee proteins of increasing intrinsic disorder-cytochrome c, the tumor suppressor protein p53 DNA bindi

258 The surprising finding is that, unlike for cytochrome c, there is an observable folding intermediat

259 nted, display remodelled cristae and release cytochrome c, thereby driving apoptosis.

260 imilar to the previously reported results on cytochrome c, these fragment ions form near residues kno

261 d in the presence of cytosol did not release cytochrome c, they displayed a dramatic increase in sens

262 that reduced DSD-Fdm transfers electrons to cytochrome c, thus generating the reduced cyt c stoichio

263 r binding affinity of rebaudioside A towards cytochrome c, thus supporting their host-guest relations

264 ] of the four model proteins ranged from 20 (cytochrome c) to 800 amol (BSA).

265 id hydrolysis to degrade a standard protein, cytochrome c, to produce many di/tripeptides with known

266 ase uses electrons donated by its substrate, cytochrome c, to reduce oxygen to H2O.

267 t with MPH (10mg/kg) decreased caspase-3 and cytochrome c; treatment with MPH (2 and 10mg/kg) increas

268 abilities are demonstrated for ubiquitin and cytochrome c, two common model proteins for structure an

269 obilities of single multiply charged ions of cytochrome c, ubiquitin, myoglobin, and bovine serum alb

270 A major relaxation of heme ruffling in cytochrome c, upon binding to the mitochondrial membrane

271 ein SERS spectra of a layer of test protein, Cytochrome-c, using a custom-made Otto-Raman spectroscop

272 reactivity of the reduced FMN domain toward cytochrome c; (v) response to calmodulin binding; and (v

273 y mixed-spin (sextet-quartet) heme center in cytochrome c' was investigated by electron nuclear doubl

274 Cytochrome c' was obtained from overexpressing variants

275 of model proteins in aqueous media, such as cytochrome c, was also examined, yielding spectra with a

276 In experiments using cytochrome c, we distinguish dynamic behavior in loops,

277 functionally relevant structural changes in cytochrome c, we measured the absorption and electronic

278 er metal porphyrins can be incorporated into cytochromes c, we engineered Escherichia coli so that th

279 ins (transferrin, myoglobin, hemoglobin, and cytochrome c) were separated by high-performance liquid

280 ng dichlorodihydrofluorescence diacetate and cytochrome c, were rapidly and significantly increased f

281 the SH3 domain, dihydrofolate reductase, and cytochrome c, where the transparent window vibrational p

282 calmodulin (CaM)-free and CaM-bound nNOS to cytochrome c, whereas hinge lengthening relieved repress

283 ngly abolish formation of both holo-CcmE and cytochrome c, whereas previously reported point mutation

284 MOM permeabilization, causing the release of cytochrome c, which effectively commits the cell to die.

285 ith anionic lipids (such as cardiolipin) and cytochrome c, which exerts a peroxidase activity.

286 eabilization (MOMP), allowing the release of cytochrome c, which interacts with Apaf-1 to trigger cas

287 Later, the cell body mitochondria release cytochrome c, which is followed by caspase activation, a

288 tion and inhibits the peroxidase activity of cytochrome c, which is involved in its release from mito

289 Assays that were based on cytochrome c, which is not a physiologic substrate for P

290 2)S also reduces CcO's biological reductant, cytochrome c, which normally derives its reducing equiva

291 hondrial damage and translocation of Bax and cytochrome c, which were then followed by caspase-3 acti

292 n aberrant activation of a testis isoform of cytochrome c, which, albeit expressed at low levels, was

293 different proteins (Trp-cage, myoglobin, and cytochrome c) with folding time constants that differ by

294 1 functioned as a translational repressor of cytochrome c, with interventions to silence TIA-1 dramat

295 erric forms of Met80X mutants of yeast iso-1-cytochrome c (X = Ala, Ser, Asp, and Glu) display EPR an

296 roxidase (ZnCcP) in complex with yeast iso-1-cytochrome c (yCc) diffract to higher resolution (1.7 A)

297 ection values of the charge states of equine cytochrome c (z = 9-16), and values are in good agreemen

298 e demonstrate that Zn(II) porphyrin in Zn(II)cytochrome c (Zn cyt c) is a fluorescence resonance ener

299 phyrin (ZnP) chromophore in zinc-substituted cytochrome c (Zn-cyt c) and an Alexa Fluor dye attached

300 ctron-transfer reactions of zinc-substituted cytochrome c, ZnCyt-c, immobilized on mesoporous, nanocr