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1 ed with changes in localization of auxin and cytokinin.
2 oots and which has previously been linked to cytokinin.
3 he production of chlorophyll are enhanced by cytokinin.
4 itivity to auxin and enhanced sensitivity to cytokinin.
5 a reduced concentration of the plant hormone cytokinin.
6 sitivity to auxin and reduced sensitivity to cytokinin.
7 tly correlates with the transport of the fed cytokinin.
8 or sensitivity to ethylene, gibberellin, or cytokinin.
9 s, such as the signaling of the phytohormone cytokinin.
10 nistic interaction of the hormones auxin and cytokinin.
11 hormones, including auxin, strigolactone and cytokinin.
12 actors that are transcriptionally induced by cytokinin.
13 KX), an enzyme catalyzing the degradation of cytokinins.
14 catalyzes the production of hormones called cytokinins.
15 an obligate human pathogen secretes several cytokinins.
16 shoot) translocation of the root-synthesized cytokinins.
17 tory processes, including those activated by cytokinins.
18 trations of selected plant hormones (auxins, cytokinins, abscisic acid and jasmonates), and in the nu
20 evated amounts of indole acetic acid, active cytokinins, active gibberellin, and salicylic acid were
21 e dark through the manipulation of auxin and cytokinin activity as well as through the activation of
24 the combination of simple synthesis, lowered cytokinin activity, and enhanced inhibitory effects on C
28 While the receptors are central regulators, cytokinin also is accumulated during early phases of sym
31 ahp6 mutants are hypersensitive to exogenous cytokinin and 1-napthylphthalamic acid (NPA), highlighti
33 ects; and the interplay among ABA, ethylene, cytokinin and auxin is tissue-specific, as evidenced by
34 In summary, these mechanisms self-regulate cytokinin and auxin signaling domains, ensuring correct
35 ements, along with points of cross talk with cytokinin and auxin, by which ethylene negatively regula
36 , we show here that two major phytohormones, cytokinin and auxin, display different yet partially ove
37 the control of ARR10 and AUX1 expression by cytokinin and auxin, this circuit potentially functionin
38 he local modulation of cellular responses to cytokinin and auxin, two key phytohormones regulating ce
40 ct of osmotic stress on abscisic acid (ABA), cytokinin and ethylene responses and how they mediate au
41 alling (TCS) systems play important roles in cytokinin and ethylene signalling in Arabidopsis thalian
43 d a genetic approach to evaluate the role of cytokinin and its signaling pathway in the light-induced
49 volves auxin regulation of systemic signals, cytokinins and strigolactones, which can move into axill
55 or establishing how crosstalk between auxin, cytokinin, and ethylene regulates patterning in root dev
57 signaling pathways mediated by gi, GA, SPY, cytokinins, and sex1 that are required for chloroplast b
60 1-LIKE HOMEOBOX (KNOXI) proteins, auxin, and cytokinin are known to play essential roles in SAM devel
61 nes and the biosynthetic genes for auxin and cytokinin are significantly altered in the Osarid3 mutan
65 ress as a negative regulator to control this cytokinin-associated module of CRF6-dependent genes and
68 ocusing on the earliest stages, we propose a cytokinin-auxin feedback model during early gynoecium pa
69 signaling element that determines the auxin/cytokinin balance during nodule development in soybean (
71 ins emulate the structural changes caused by cytokinin binding, resulting in domain motion propagatin
75 r responsiveness of these genes confirm that cytokinin biosynthesis is a key target of the common sym
78 ed distinct differences in the expression of cytokinin biosynthesis, catabolism and signaling genes i
81 lation, we followed transcript levels of the cytokinin biosynthetic pathway genes in a sliding develo
82 ed that the Rv1205-dependent accumulation of cytokinin breakdown products is likely responsible for t
85 by a balance between positive regulation by cytokinin (CK) and negative regulation by CLAVATA (CLV).
89 Strikingly, early epidermal activation of cytokinin (CK) pathways was indicated, based on the indu
90 uppress gibberellin signaling and to promote cytokinin (CK) responses, its catalytic OGT activity was
91 time, and senescence downstream from auxin, cytokinin (CK), gibberellin (GA), and light signaling.
94 ature, causes severe depletion of endogenous cytokinins (CKs) in the model plant Arabidopsis (Arabido
97 , in addition to showing an elevated cambial cytokinin content and signaling level, the cambial auxin
99 dependent upon cytokinin signaling and that cytokinins could activate glutaredoxin gene expression i
100 we report the identification of REPRESSOR OF CYTOKININ DEFICIENCY 1 (ROCK1, At5g65000) as an ER-local
101 the AHK2 and AHK3 genes, named repressor of cytokinin deficiency2 (rock2) and rock3, respectively.
103 In addition, crosses between "long-root" cytokinin-deficient plants and "long-root" glutaredoxin-
104 A new study shows that another hormone, cytokinin, degrades PINs on specific membranes to direct
105 ression is caused by the loss of activity of cytokinin-degrading enzymes, cytokinin oxidases/dehydrog
108 cytokinin response pathway that involves the cytokinin-dependent stability control of a major RRB res
110 rs of HEMA1 and LHCB6 genes, indicating that cytokinin-dependent transcription factors directly regul
114 t branching by elevating contents of GA3 and cytokinins due to upregulated transcript levels of sever
115 sis revealed that the protective function of cytokinin during light stress depends on the Arabidopsis
116 tified as a direct target of ARR10, with its cytokinin-enhanced expression resulting in enhanced shoo
118 atterning in the aux1 mutant, the amounts of cytokinin, ethylene and PIN protein, and PIN protein pat
119 i6A), a modified nucleoside belonging to the cytokinin family, has shown in humans many biological ac
120 the translocation of trans-zeatin (tZ)-type cytokinins from roots to shoots, thereby affecting the p
122 cies, we conducted a comparative analysis of cytokinin genes in response to the beet cyst nematode (B
124 e CRFs results in partially insensitivity to cytokinin in a root elongation assay and affects the bas
125 Previous studies have suggested a role for cytokinin in feeding site formation induced by these two
126 a point of convergence for both ethylene and cytokinin in negatively regulating cell proliferation.
127 f CKX3 on the positive and negative roles of cytokinin in nodule development, infection and regulatio
129 re generated and used to clarify the role of cytokinin in regulation of various physiological respons
130 ew, we focus on the interaction of auxin and cytokinin in several developmental contexts, including i
132 est that AtGRXS3/4/5/8 operate downstream of cytokinins in a signal transduction pathway that negativ
136 rabidopsis, endosperm formation requires the CYTOKININ INDEPENDENT 1 (CKI1) histidine kinase, an acti
137 the receiver domain of the histidine kinase CYTOKININ-INDEPENDENT 1 (CKI1RD) from Arabidopsis thalia
138 e for spatiotemporally correct expression of CYTOKININ INDEPENDENT1 (CKI1), encoding the constitutive
139 haracterization of an auxin deficient mutant cytokinin induced root curling 2 (ckrc2) in this work re
142 ic elements in a regulatory network by which cytokinin inhibits root cell elongation in concert with
147 the classical functions of the plant hormone cytokinin is the regulation of plastid development, but
149 veals that an informative spatial pattern in cytokinin levels generated by diffusion is a theoretical
150 either a specific consequence of the altered cytokinin levels in amp1 nor directly mediated by the WU
151 have also shown that direct manipulation of cytokinin levels in transgenic plants has dramatic effec
153 ytokinin response, rather than variations in cytokinin levels, allow for the necessary feedbacks, whi
154 eptor AHK2 and is characterized by increased cytokinin levels, downregulation of cytokinin signaling
157 depends on mutual feedback between auxin and cytokinins mediated by the PIN class of auxin efflux tra
158 at mycorrhization and Pi fertilization share cytokinin-mediated improved shoot growth, whereas enhanc
162 signaling domains of the hormones auxin and cytokinin mirror their embryonic dynamics and manipulati
164 ivisions with negative regulatory effects of cytokinin on infection events and root development.
166 tton defoliant, is a well known inhibitor of cytokinin oxidase/dehydrogenase (CKX), an enzyme catalyz
167 Here, we show that the Lotus japonicus Ckx3 cytokinin oxidase/dehydrogenase gene is induced by Nod f
169 mbiotic marker, while a CK-degrading enzyme (CYTOKININ OXIDASE/DEHYDROGENASE3) ectopically expressed
172 ely overlooked link between the ethylene and cytokinin pathways, which acts through a phosphorelay me
173 tion in the actively dividing cambial cells, cytokinins peak in the developing phloem tissue of a Pop
174 initiate nodules in the Medicago truncatula cytokinin perception mutant cre1 (cytokinin response1) i
175 (CRFs), transcription factors downstream of cytokinin perception, transcriptionally control genes en
180 RESPONSE REGULATORs (ARRs) that mediate the cytokinin primary response, making use of chromatin immu
181 thereby defining a crucial link between the cytokinin primary-response pathway and the transcription
182 ipts was a set of five genes associated with cytokinin processes: (signaling) ARR6, ARR9, ARR11, (bio
185 allus production in this mutant requires the cytokinin receptor AHK2 and is characterized by increase
186 sufficient to promote the expression of the cytokinin receptor Cytokinin Response 1 (CRE1), which is
187 alysis of the Lotus histidine kinase1 (Lhk1) cytokinin receptor gene has shown that it is required an
188 L. japonicus contains a small family of four cytokinin receptor genes, which all respond to M. loti i
189 n, we provide data to support a role for the cytokinin receptors AHK2 and AHK3 in light-induced stoma
192 psis thaliana were used to study the role of cytokinin receptors in the expression of chloroplast gen
193 ines revealed contrasting differences in the cytokinin receptors mediating cell cycle activation in f
194 Surprisingly, we identified a subfamily of cytokinin receptors with members only from the early div
195 basal expression of a significant number of cytokinin-regulated genes, including the type-A ARRs, al
196 l primordium and strengthen the concept that cytokinin regulates auxin homeostasis during gynoecium d
197 of type-B ARR activation, and basis by which cytokinin regulates diverse aspects of growth and develo
199 n and ethylene, and support a model in which cytokinin regulates shootward auxin transport to control
200 , thereby, increased seed yield suggest that cytokinin regulates various aspects of reproductive grow
201 ples PIN transcription from the CRF-mediated cytokinin regulation and attenuates plant cytokinin sens
203 ote the expression of the cytokinin receptor Cytokinin Response 1 (CRE1), which is restricted to the
207 e presence of AN3 at the loci of GRF5, GRF6, CYTOKININ RESPONSE FACTOR2, CONSTANS-LIKE5 (COL5), HECAT
210 ype-A RRs (RRAs) that are encoded by primary cytokinin response genes and function as response inhibi
211 al activators that promote the expression of cytokinin response genes and the type-A RRs (RRAs) that
212 al an additional regulatory mechanism in the cytokinin response pathway that involves the cytokinin-d
213 ociations characterized the growth-promoting cytokinin response regulator ARR1, and the wood developm
215 al role of the type-B ARRs in regulating the cytokinin response, mechanism of type-B ARR activation,
216 Instead, auxin-dependent modifications of cytokinin response, rather than variations in cytokinin
217 tive CKs in roots and negatively impacts the Cytokinin Response1 (CRE1)-dependent NF activation of a
218 truncatula cytokinin perception mutant cre1 (cytokinin response1) is due to its altered ability to re
219 responses increase under osmotic stress, but cytokinin responses are only slightly reduced; inhibitio
220 tting tract formation, affect both auxin and cytokinin responses during reproductive tissue developme
221 er AUX1 functions as a positive regulator of cytokinin responses in the root; mutation of AUX1 specif
222 HEC1 acts as a local modulator of auxin and cytokinin responses to control gynoecium development in
223 ana) Cytokinin Response Factor 6 (CRF6) is a cytokinin-responsive AP2/ERF-family transcription factor
224 LISM-INVOLVED (GNC) and its paralog GNC-LIKE/CYTOKININ-RESPONSIVE GATA FACTOR1 (GNL), have already be
225 LE, CARBON METABOLISM-INVOLVED) and GNC-LIKE/CYTOKININ-RESPONSIVE GATA FACTOR1 as well as that of SPC
226 METABOLISM-INVOLVED (GNC) and GNC-LIKE (GNL)/CYTOKININ-RESPONSIVE GATA FACTOR1 is controlled by sever
228 show that boundary formation is dependent on cytokinin's control on auxin polar transport and degrada
229 ly increased amounts of active gibberellins, cytokinins, salicylic acid, and jasmonate compared with
232 with misregulation of MSP signaling, changed cytokinin sensitivity, and developmental aberrations tha
235 f the cytokinin response using the synthetic cytokinin sensor, TCSn, showed that this response occurs
236 an important role of ROCK1 in regulating the cytokinin signal in the meristematic cells through modul
237 In Arabidopsis (Arabidopsis thaliana), the cytokinin signal is perceived by three membrane-located
238 the root epidermis is sufficient to promote cytokinin signaling and nodule organogenesis in the inne
240 taredoxin gene expression was dependent upon cytokinin signaling and that cytokinins could activate g
241 ignaling in Arabidopsis and the elevation in cytokinin signaling appears to be responsible for the at
243 To explore the functional significance of cytokinin signaling for cambial development, we engineer
249 shown the requirement for receptor-mediated cytokinin signaling in symbiotic nodule organogenesis.
250 that TEM also acts as a link between GA and cytokinin signaling in the epidermis by negatively regul
252 ncreased cytokinin levels, downregulation of cytokinin signaling inhibitors ARR7 and ARR15, and induc
253 Our results suggest that CRE1-dependent cytokinin signaling leads to nodule initiation through t
255 esults demonstrate an important role for the cytokinin signaling pathway in chloroplast development,
256 on by CKI1 likely involves activation of the cytokinin signaling pathway mediated by histidine phosph
257 amily transcription factor that, through the cytokinin signaling pathway, plays a key role in the inh
258 (CKI1) histidine kinase, an activator of the cytokinin signaling pathway, which specifies central cel
260 symbiotic nodule development in legumes, and cytokinin signaling responses occur locally in nodule pr
262 ed by a development-specific derepression of cytokinin signaling that involves cross talk with signal
264 ion of symbiotic nodules in legumes requires cytokinin signaling, but its mechanism of action is larg
265 -term Cr(VI)-regulated genes are involved in cytokinin signaling, the ubiquitin-proteasome system pat
273 lly inhibitory interaction between auxin and cytokinin, signaling through SHR, microRNA165/6, and PHA
274 ere we show a direct regulatory link between cytokinin signalling and the auxin transport machinery u
275 that AHP6-based fields establish patterns of cytokinin signalling in the meristem that contribute to
277 the integrated action of auxin, ethylene and cytokinin signalling, the POLARIS protein, and the funct
280 o circadian stress regimes requires a normal cytokinin status which, acting primarily through the AHK
281 We demonstrate that in plants with a reduced cytokinin status, the D1 protein level was strongly decr
282 tems, was decreased in plants with a reduced cytokinin status, which could be a cause for the increas
283 e genes was correlated with higher levels of cytokinin/sugar signaling in growing buds of wild-type p
284 ms and many related to phytohormones such as cytokinin, suggesting that Xa21 triggered redistribution
286 r with the rapid repression of both genes by cytokinin, this indicates that LjIpt2 and LjLog4 contrib
287 al stage-specific sensitivities to auxin and cytokinin to direct proper nodule formation and maturati
288 ignaling contributes but is not required for cytokinin to inhibit activity of the root meristem.
289 of AUX1 specifically affects the ability of cytokinin to inhibit cell elongation but not cell prolif
294 n of transplastomic plants on medium lacking cytokinin was as effective as selection on medium contai
295 f ARR10, Arabidopsis lines hypersensitive to cytokinin were generated and used to clarify the role of
298 ulatory circuits controlling interactions of cytokinin with auxin and ethylene, and support a model i
300 ults are consistent with a model wherein the cytokinin/WUS pathway and retrograde signaling control c
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