ライフサイエンスコーパス: cytolysis

1 ial cells (i.e. apoptosis, barrier function, cytolysis).

2 ting cytoplasmic vacuolization and, finally, cytolysis.

3 g of tumors that are usually resistant to NK cytolysis.

4 umans, are highly susceptible to PVL-induced cytolysis.

5 ot mediate resistance to CD8 T cell-mediated cytolysis.

6 sceptible to perforin-dependent CTL-mediated cytolysis.

7 lls occurs through TAA-specific CTL-mediated cytolysis.

8 omal destabilization correlated closely with cytolysis.

9 usceptibility of tumor cells to CTL-mediated cytolysis.

10 satory manner dominated by perforin-mediated cytolysis.

11 fic IL-10-positive CD8(+) T cells suppressed cytolysis.

12 e absolutely resistant to leukotoxin-induced cytolysis.

13 in vitro blocks tumor-induced defective TIL cytolysis.

14 ells without the direct contact required for cytolysis.

15 ied and typically results in virally induced cytolysis.

16 cell-derived IFN-gamma via perforin-mediated cytolysis.

17 T-cell alloresponses, and were targets of NK cytolysis.

18 ntrations, far below those required to cause cytolysis.

19 ct of CTLA4-Ig and rapamycin on DSA-mediated cytolysis.

20 nt destruction of cancer cells through rapid cytolysis.

21 the cytoskeletal rearrangements required for cytolysis.

22 oliferation, cytokine secretion, and natural cytolysis.

23 assayed by anti-NKG2D Ab-mediated redirected cytolysis.

24 a-herpesvirus CMV through perforin-dependent cytolysis.

25 FasL signaling also contributed to enhanced cytolysis.

26 uptake and dilated blebbing coincident with cytolysis.

27 9 demonstrated both IFN- gamma secretion and cytolysis.

28 function, including their ability to mediate cytolysis.

29 ity of normal platelets to protect them from cytolysis.

30 s and protected them from leukocyte-mediated cytolysis.

31 ue to reduced adhesion rather than increased cytolysis.

32 is factor alpha (TNF-alpha)- and Fas-induced cytolysis.

33 itro and in vivo, inducing proliferation and cytolysis.

34 1,3-Gal] inhibited both antibody binding and cytolysis.

35 M-CSF but prevented adhesion, spreading, and cytolysis.

36 e tumor by IFN-gamma production and specific cytolysis.

37 ivity to anthrax lethal toxin (LeTx)-induced cytolysis.

38 ss perforin, a molecule that is required for cytolysis.

39 ion to its defect in pore formation-mediated cytolysis.

40 kely reflecting eosinophil degranulation via cytolysis.

41 d-defective Lm is largely independent of CTL cytolysis.

42 members capable of mediating CPE binding and cytolysis.

43 activated ras are also susceptible to viral cytolysis.

44 functions including cytokine production and cytolysis.

45 centration induced passive degranulation via cytolysis.

46 fected subjects correlated with CMV-specific cytolysis.

47 inding and trigger subsequent toxin-mediated cytolysis.

48 interleukin-2 (IL-2)-activated cell-mediated cytolysis.

49 MAPK or autophagy did not affect PLO-induced cytolysis.

50 mpetent and capable of mediating/redirecting cytolysis.

51 cidate the molecular mechanism of eosinophil cytolysis.

52 functions, including IFN-gamma secretion and cytolysis.

53 ting cytokines and through contact-dependent cytolysis.

54 ion to ligand-expressing targets and enhance cytolysis.

55 is threshold can be reached without inducing cytolysis.

56 s, all strains show strict contact-dependent cytolysis.

57 cells also significantly impairs TCR-induced cytolysis.

58 vated NK cells susceptible to NKp80-mediated cytolysis.

59 notion that NETs can form during nonspecific cytolysis.

60 Listeria involved specialized utilization of cytolysis.

61 and promote NK cell-mediated recognition and cytolysis.

62 MTOC polarization and defective target cell cytolysis.

63 ut do not support full activation or sustain cytolysis.

64 the interface center were closely related to cytolysis.

65 ced activity in the patient population (K562 cytolysis, 19% +/- 21% SD versus 40% +/- 17%) (P < .001)

66 lymphocytes (TIL) are severely deficient in cytolysis, a defect that may permit tumor escape from im

67 an host, but induces pore formation-mediated cytolysis after termination of intracellular replication

68 treated human NK cells exhibit reduced tumor cytolysis and abrogated perforin polarization to the imm

69 alpha was mainly responsible for enhanced NK cytolysis and also important for CD69 up-regulation, whe

70 s that degrade basement membranes and induce cytolysis and apoptosis of the cellular elements of the

71 s linked to the ability of betaH/C to induce cytolysis and apoptosis of the phagocytes.

72 of basal keratinocytes leading to epidermal cytolysis and blistering.

73 ectors of the innate immune response through cytolysis and bridge to the adaptive immune response thr

74 on of cell surface P2X7 receptors results in cytolysis and cell death of macrophages.

75 noma cell susceptibility to NK-cell-mediated cytolysis and cisplatin-induced apoptosis.

76 elanoma cell sensitivity to NK-cell-mediated cytolysis and cisplatin-induced apoptosis.

77 -dependent proliferation and specific target cytolysis and cytokine production were retained after al

78 This induces effector functions such as cytolysis and cytokine release.

79 IV-specific CD8+ T cells were discordant for cytolysis and cytokine secretion, notably IFN-gamma, whe

80 -6/CFP-10 deletion mutant all showed reduced cytolysis and cytotoxicity to macrophages and significan

81 phage lysis could play a role in LT-mediated cytolysis and discovered that a potent P2X7 antagonist,

82 but are defective in pore formation-mediated cytolysis and egress from mammalian and protozoan cells,

83 was not involved in pore formation-mediated cytolysis and egress from mammalian and protozoan cells.

84 as the rib mutant in pore formation-mediated cytolysis and egress from mammalian and protozoan cells.

85 ular replication and pore formation-mediated cytolysis and egress from mammalian cells.

86 ion but defective in pore formation-mediated cytolysis and egress from protozoan and mammalian cells.

87 lecules resulted in increased serum-mediated cytolysis and eliminated the costimulatory blockade.

88 es primary breast carcinomas to CPE-mediated cytolysis and emphasizes the potential of CPE in breast

89 MCPT4]), BECs underwent caspase-1-associated cytolysis and exfoliation.

90 The contributions of perforin-mediated cytolysis and gamma interferon (IFN-gamma) secretion by

91 -positive CD8+ T cells resulted in increased cytolysis and IL-2, but not IFN-gamma, production by bot

92 tead leads to changes in genes implicated in cytolysis and NK cell function.

93 t KSR1 is required for efficient NK-mediated cytolysis and polarization of cytolytic granules.

94 type CTL, gld-CTL efficiently mediated tumor cytolysis and produced comparable amounts of IFN-gamma,

95 inflammation in mice can involve eosinophil cytolysis and release of cell-free granules.

96 d have redundant effector functions, such as cytolysis and release of potent antimycobacterial cytoki

97 T cells from normal human donors that induce cytolysis and secrete copious IFN-gamma in response to s

98 gh two contact-dependent effector functions: cytolysis and secretion of antiviral cytokines.

99 ersus control cells, thus establishing viral cytolysis and spread as the cause of the observed cell k

100 0 and p865 CTLs as shown by peptide-specific cytolysis and tetramer staining, indicating that hTERT i

101 our knowledge of the mechanisms of host cell cytolysis and the egress of intracellular pathogens is s

102 Expression of CD107a (a marker of cytolysis) and production of IFN-gamma and macrophage in

103 lls (suppressor cytokines, IL-2 consumption, cytolysis) and those that primarily target antigen-prese

104 ization is known to enhance NK cell-mediated cytolysis, and a potential mechanism for Crry-mediated i

105 rometastases, an increase in target-specific cytolysis, and an increase in survival correlated with d

106 er cell- and cytotoxic T-lymphocyte-mediated cytolysis, and CD4 T-cell alloproliferation.

107 functions including cytokine production and cytolysis, and differentiate into long-lived memory cell

108 irulence in animal models, mediates cellular cytolysis, and inhibits IL-12 production by mononuclear

109 es, we assessed the efficiency of infection, cytolysis, and replication of green fluorescent protein

110 chronically infected HIV+ individuals, e.g., cytolysis, and secretion of gamma interferon (IFN-gamma)

111 ibility to natural killer (NK) cell-mediated cytolysis, and sensitivity to apoptosis were assessed.

112 Antibody blocking, redirected cytolysis, and small interfering RNA (siRNA) studies usi

113 are abnormal, with greater than 80% showing cytolysis, and therefore that evaluation by means of lig

114 al responses including IFN-gamma production, cytolysis, and tumor homing, suggesting that NK cells wi

115 Perforin-dependent cytolysis appeared to be the major cytolytic mechanism;

116 ic hepatitis C, but higher levels of NK cell cytolysis are associated with less liver fibrosis.

117 esis of antiviral beta-chemokines has joined cytolysis as a potential mechanism for the control of HI

118 protected stromal cells against PLO-induced cytolysis as determined by 3-(4,5-dimethylthiazol-2-yl)-

119 Ia-restricted CTLs, however, were capable of cytolysis as measured by redirected killing.

120 r target cell deposition during the in vitro cytolysis assay.

121 Unlike cytolysis assays with macrophages, E6 expression did not

122 In additional cytolysis assays, UL18-mediated protection was also evid

123 lization signal of VP4 were required for (i) cytolysis associated with prolonged expression; (ii) nuc

124 d in a dose-dependent manner and showed 100% cytolysis at a multiplicity of infection of 0.1.

125 We confirmed cytolysis at antigen levels similar to those on primary

126 a distinct form of cell vacuolation precedes cytolysis at low doses of hemolysin.

127 rment, however, was restricted to LT-induced cytolysis, because proteasome inhibitors did not block c

128 (i.e., proliferation, IFN-gamma production, cytolysis) between adult and old memory T cells.

129 o eliminate virally infected cells by direct cytolysis but may also contribute to pulmonary inflammat

130 tly via IFN-gamma production or directly via cytolysis, but evidence for either mechanism is largely

131 elper (Th)1 and Th2 cytokines and to mediate cytolysis, but it is unclear how these contrasting funct

132 o created to compare their susceptibility to cytolysis by diabetogenic CD8(+) T-cells in vitro.

133 nsertion of the D4 loops is required for the cytolysis by ILY.

134 nd VP3(101-120)) sensitized target cells for cytolysis by infiltrating T cells or splenic T cells fro

135 , this viral peptide inhibits HLA-E-mediated cytolysis by natural killer cells.

136 ion levels suggesting that the resistance to cytolysis by rSUM149 cells was not related to MHC class

137 Our data demonstrate that the hemolysis and cytolysis by S. aureus were noticeably augmented when S.

138 rations was relatively resistant in vitro to cytolysis by sensitized T cells, whether the eyecups wer

139 This 9-mer serves to direct cytolysis by T cell lines, whereas a related 10-mer (E7(

140 effect of dexamethasone on brain tumor cell cytolysis by TALL-104 cells; (d) explored the effects of

141 ) cytolytic NK cells (P = .02), overall K562 cytolysis by unfractionated peripheral blood mononuclear

142 NK cell cytolysis can be induced directly through diverse recept

143 Cytolysis capacity of steroid-treated Acanthamoeba was q

144 partially dependent on complement-dependent cytolysis (CDC), in which the immune system surveys for

145 ve CD8(+) T cells led to higher HIV-specific cytolysis compared with the removal of Nef-specific IL-1

146 Levels of adherence and cytolysis correlate for weakly adherent/cytolytic strain

147 results identified no global differences in cytolysis, degranulation, interferon-gamma production, o

148 Our data imply that cytolysis does not correlate with MEK1 cleavage, and thi

149 iltrating lymphocytes (TIL) are defective in cytolysis due to tumor-induced inhibition of proximal TC

150 n vitro resulted in rapid and dose-dependent cytolysis exclusively in breast cancer cells, correlatin

151 ith CPE resulted in rapid and dose-dependent cytolysis exclusively in cells that expressed CLDN 3 and

152 tial susceptibility of murine macrophages to cytolysis following in vitro exposure to LT, was identif

153 avidity is indicated by the independence of cytolysis from CD8/MHC class I interaction.

154 epithelial cells require a specific cue for cytolysis from recruited sentinel inflammatory cells bef

155 f this polarization and their importance for cytolysis have not been resolved.

156 achment was found to be necessary to trigger cytolysis; however, this threshold can be reached withou

157 cancer cells susceptible to NK cell-mediated cytolysis if expressed at sufficiently high levels.

158 , potassium, and magnesium in the absence of cytolysis, implicating these ion movements in the toxin'

159 and demonstrated efficient cancer-selective cytolysis in a variety of tumor cell lines, including HT

160 oguanidine (MNNG), both cell lines underwent cytolysis in a very similar manner, suggesting the prese

161 (2)) as a central molecule in NKG2D-mediated cytolysis in CTLs.

162 advances the current view of the role of CTL cytolysis in immunity to intracellular pathogens.

163 Differential resistance to cytolysis in metastatic versus primary prostate cancer c

164 e evaluated the effects of ITK deficiency on cytolysis in murine CTLs deficient in ITK, and both huma

165 rmine the contribution of perforin-dependent cytolysis in protective immunity to LM.

166 necrosis factor receptor 1 (TNFR1)-mediated cytolysis in regulating T-cell homeostasis.

167 sensitivity to natural killer cell-mediated cytolysis in vitro and rejection in vivo.

168 M plays a role in perforin/granzyme-mediated cytolysis in vitro.

169 l or stromal cells from trophozoite-mediated cytolysis in vitro.

170 ons display predominantly perforin-dependent cytolysis in vitro.

171 IL-4 and IL-5 and display perforin-dependent cytolysis in vitro.

172 s was safe and induced T-cell activation and cytolysis, including HIV-1-infected cells, in a subset o

173 Interestingly, triggering cytolysis is associated with an induction of autophagy i

174 We found that CTL cytolysis is critical for protective immunity to Lm capa

175 The mechanism for LT-induced cytolysis is currently unknown.

176 Cytolysis is largely Fas dependent and results from very

177 ayed-type hypersensitivity and that cellular cytolysis is the root cause of the necrosis.

178 emonstrate that an important function of CTL cytolysis is to counter the microbial virulence strategy

179 g a new method of detecting NK cell-mediated cytolysis, it was observed that NK cells efficiently lys

180 cytes and astrocytes of the CNS, it produces cytolysis, leading to formation of demyelinated lesions

181 Cytolysis levels displayed even greater variability, fro

182 ypothesized that immunological approaches to cytolysis may be used to overcome drug resistance.

183 wer than or equal to those that cause direct cytolysis, may alter the phenotype of target tissue by u

184 Consequently, PCC were highly resistant to cytolysis mediated by freshly isolated NK cells.

185 Rather than inducing cytolysis, membrane attack complexes upregulated inflamm

186 anemia, abdominal tenderness, severe hepatic cytolysis, metabolic acidosis, and hemodynamic dysfuncti

187 ysis of GalT(+) target cells, with extensive cytolysis observed consistently at serum IgM titers of >

188 free or clustered, indicate that eosinophil cytolysis occurs in vivo, but the mechanisms and consequ

189 TCR-dependent recognition leading to direct cytolysis of aminobisphosphonate-sensitized osteoclast o

190 8F4 mediated complement-dependent cytolysis of AML blasts and Lin(-)CD34(+)CD38(-) leukemi

191 o-GM1 antiserum in vivo and NK-cell-mediated cytolysis of B16LS9 melanoma cells in vitro.

192 ylation of the cytosolic domain of CD18, and cytolysis of bovine leukocytes.

193 mine whether CD95-L was sufficient to induce cytolysis of CD40-activated CLL cells, we used Chinese h

194 uction but increased perforin expression and cytolysis of cell line K562 targets.

195 cribes antigen-specific CD8+ T cell-mediated cytolysis of cognate antigen-expressing melanoma cells i

196 P-deficient NK cells that prevents efficient cytolysis of complex targets.

197 receptors is crucial for NK recognition and cytolysis of complex targets.

198 The capacity of aPA and MIP-133 to induce cytolysis of corneal epithelial cells was tested in vitr

199 We investigated phagocytosis and cytolysis of cultured human breast cancer cells by monoc

200 o phosphoantigens and tumor cells, prevented cytolysis of Daudi B cells, and reduced cytokine product

201 sized to provide a first line of defence via cytolysis of dysregulated intestinal epithelial cells (I

202 , from no detectable cytolysis to 80% or 90% cytolysis of Ect1 and BPH-1, respectively.

203 ither inducing apoptosis or mediating direct cytolysis of effector T cells.

204 also did not correlate with adherence to or cytolysis of either male (BPH-1)- or female (Ect1)-deriv

205 HF are not the direct result of EBOV-induced cytolysis of endothelial cells, and are likely triggered

206 MUC-2, preventing parasite contact-dependent cytolysis of epithelial cells.

207 rovoke PKR-mediated apoptosis but did induce cytolysis of fibroblasts via activation of caspase-9.

208 ti-Gal antibodies caused complement-mediated cytolysis of GalT(+) target cells, with extensive cytoly

209 demonstrated Ag-specific, non-MHC-restricted cytolysis of h5T4-positive B16 and CT26 tumor cells in v

210 Finally, in vitro IFN-alpha2a-activated NK cytolysis of HCV-infected target cells was in part depen

211 p blood agar and quantitative measurement of cytolysis of human lung epithelial cells.

212 xia-dependent E1A expression and conditional cytolysis of hypoxic but not normoxic cells.

213 pression, viral replication, and conditional cytolysis of hypoxic, but not normoxic cells.

214 in protection and control of HIV-1 by direct cytolysis of infected cells and by suppression of viral

215 tor and memory cells, a critical step in the cytolysis of infected cells.

216 Viral clearance involves immune cell cytolysis of infected cells.

217 ag and pol after vaccination, which suggests cytolysis of infected cells.

218 ertain infections and malignancies by direct cytolysis of infected or transformed cells and by secret

219 ly localized; this may reflect viral-induced cytolysis of infected tumor cells and limited lateral sp

220 responses to anthrax infection contribute to cytolysis of LeTx- resistant macrophages.

221 factors other than LeTx are involved in the cytolysis of LeTx-resistant macrophages in vivo.

222 SV-1) is equally effective in promoting PBMC cytolysis of leukemic cells and is 1000- to 10 000-fold

223 Mechanistically, UV-HSV-1 stimulates PBMC cytolysis of leukemic cells, partly via Toll-like recept

224 blocked LT-mediated caspase-1 activation and cytolysis of LT-sensitive (Fischer and Brown-Norway) rat

225 rotozoan host, the induction of necrosis and cytolysis of macrophages by L. pneumophila is mediated b

226 Although LeTx-induced cytolysis of macrophages plays an important role in the

227 NKp80-AICL interaction promotes cytolysis of malignant myeloid cells, but also stimulate

228 ent in that they stimulate proliferation and cytolysis of mature T cells (classifying the variant pep

229 ainst MHC-matched tumor targets and enhanced cytolysis of MHC mismatched tumor targets.

230 nd expressed NKG2d, a marker associated with cytolysis of microbially infected and neoplastic cells.

231 K deficiency leads to a global defect in the cytolysis of multiple targets.

232 linked to anthrax lethal toxin (LT)-mediated cytolysis of murine macrophages.

233 Mechanistically, cytolysis of neuroblastoma was mediated through natural

234 Lkt-induced cytolysis of PMNs results in the release of cytotoxic co

235 tingly, the DeltaRD1 mutants failed to cause cytolysis of pneumocytes, a phenotype that had been prev

236 equently, SLAMF7-CAR T cells conferred rapid cytolysis of previously untreated and R/R primary myelom

237 ontrol in the absence of BCMA, we maintained cytolysis of primary tumor expressing both BCMA and TACI

238 In addition, the hemolysis and cytolysis of recombinant beta-hemolysin were markedly en

239 Inhibition of Lkt-induced cytolysis of ruminant leukocytes by CD18 peptide analogs

240 inds to the intact signal peptide and causes cytolysis of ruminant leukocytes, resulting in acute inf

241 convertase activity and complement-dependent cytolysis of sheep blood erythrocytes.

242 r intermediate filament assembly, leading to cytolysis of suprabasal keratinocytes and secondary hype

243 peptide and abrogation of leukotoxin-induced cytolysis of target cells.

244 essary and sufficient to mediate Lkt-induced cytolysis of target cells.

245 f serine kinases ERK1/2 and AKT and enhanced cytolysis of target cells.

246 In contrast, HVEM activation of BTLA reduced cytolysis of target cells.

247 ls function via cytokine secretion or direct cytolysis of target cells; dendritic cells (DCs) are tho

248 ), which subsequently induces activation and cytolysis of these cells.

249 vage of the signal peptide and abrogation of cytolysis of transfectants expressing bovine CD18 carryi

250 sduction, we show that NKG2D is required for cytolysis of tumor cells, including autologous tumor cel

251 ent of novel miR-targeted therapy to promote cytolysis of tumor cells.

252 e to the adenovirus vector or virus-mediated cytolysis of tumor cells.

253 activation targets MAPK and AKT during early cytolysis of tumor target cells.

254 Our studies demonstrate that ESAT6 causes cytolysis of type 1 and type 2 pneumocytes.

255 ible bone marrow transplants and in vitro by cytolysis of YAC-1 and Jurkat cells.

256 ion, NKG2D was required for NK cell-mediated cytolysis on adenovirus-infected targets.

257 surface proteins induce complement-dependent cytolysis or Ab-dependent cell-mediated cytotoxicity of

258 hat might mediate rejection by either direct cytolysis or by inducing apoptosis of the donor corneal

259 did not have either measurable CMV-specific cytolysis or secretion of IFN-gamma without in vitro sti

260 Though CVB is well known to disseminate via cytolysis, recent reports have revealed a second pathway

261 and IFN-gamma production, but not increased cytolysis, required recognition of influenza-infected DC

262 roliferation and cytokine secretion, but not cytolysis, specifically associated with synaptic accumul

263 F-H1 knockdown augmented complement-mediated cytolysis, suggesting a role for GEF-H1 and RhoA in prot

264 tumor effector function including tumor cell cytolysis, T(C)1 cytokine production, and zetakine-regul

265 We report that adhesion-induced eosinophil cytolysis takes place through RIPK3-MLKL-dependent necro

266 cells proved substantially less sensitive to cytolysis than the EBV-transformed B-cell line used for

267 ion with LF results in a macrophage-specific cytolysis that is not well understood.

268 selves diminishes target cell sensitivity to cytolysis, thereby reducing the lytic potency of IFN-gam

269 ular endothelial cells via perforin-mediated cytolysis, thereby severely compromising vascular integr

270 even greater variability, from no detectable cytolysis to 80% or 90% cytolysis of Ect1 and BPH-1, res

271 iparum and Toxoplasma gondii cause host cell cytolysis to facilitate parasite release and disease pro

272 for cytoplasmic vacuolization and subsequent cytolysis to occur.

273 fic CD8(+) T cells require perforin-mediated cytolysis to protect animals from infection.

274 ed the contribution of perforin-mediated CTL cytolysis to protective immunity against recombinant Lm

275 ridium perfringens enterotoxin (CPE) induces cytolysis very rapidly through binding to its receptors,

276 kine interferon-gamma (IFN-gamma) and induce cytolysis via releasing factors such as perforin, which

277 Cytolysis was abrogated by concanamycin A and EGTA but n

278 Furthermore, cytolysis was completely blocked when we prevented attac

279 HUVEC cytolysis was dependent on granule exocytosis, as demons

280 and propidium iodide labeled target-specific cytolysis was determined by flow cytometry.

281 The enhanced cytolysis was mediated through the perforin/granzyme pat

282 c CD4 T cell clones were cytolytic, but that cytolysis was not likely critical for controlling C. mur

283 However, Lkt-induced cytolysis was observed only with transfectants expressin

284 Direct evidence for pDC cytolysis was obtained by rapid and selective pDC deplet

285 This cytolysis was repressed by the cytoprotectant glycine, p

286 Cytolysis was triggered by NKG2D recognition of stress-i

287 feration as readout but not when target cell cytolysis was used.

288 MTX-dependent release of mIL-1beta (but not cytolysis) was inhibited by the elimination of the trans

289 MTX-induced cytokine release and cytolysis were both abrogated in the absence of extracel

290 sphorylation, cytoplasmic vacuolization, and cytolysis were observed in eosinophils under in vivo inf

291 and 1.4 nU when the ultrasonic and chemical cytolysis were used, respectively.

292 macrophages became sensitive to LeTx-induced cytolysis when these cells were activated by bacterial c

293 hesion to the integrin ligand ICAM-1 and for cytolysis, whereas phosphorylation of Tyr378 was require

294 s susceptible than human PMNs to PVL-induced cytolysis, whereas rabbit PMNs, like those of humans, ar

295 everal different mechanisms, one of which is cytolysis, which is associated with release of intact gr

296 tibility of U87 glioma cells to CTL-mediated cytolysis while ICAM-1 mRNA levels remained stable.

297 re resistant to GzmA-mediated DNA damage and cytolysis, while cells overexpressing NM23-H1 are more s

298 iving within neutrophils promotes neutrophil cytolysis, with release of host-derived molecules that p

299 carcinoma cells underwent rapid and complete cytolysis within 1 hour.

300 A sharp increase in cytolysis within 24 h was observed at MOI > or = 25.