ライフサイエンスコーパス: cytoplasmic dynein

1 nhibition of the minus-end microtubule motor cytoplasmic dynein .

2 for the minus-end-directed microtubule motor cytoplasmic dynein.

3 first specific small-molecule antagonists of cytoplasmic dynein.

4 of the cellular functions and regulation of cytoplasmic dynein.

5 f two ~300-kilodalton motor domains of yeast cytoplasmic dynein.

6 1 in the regulation of the microtubule motor cytoplasmic dynein.

7 interact directly with one another and with cytoplasmic dynein.

8 e force-dependent stepping behavior of yeast cytoplasmic dynein.

9 back to the cytoplasm (retrograde) driven by cytoplasmic dynein.

10 gene, which is involved in the regulation of cytoplasmic dynein.

11 d by myosin V, heterotrimeric kinesin-2, and cytoplasmic dynein.

12 directly modulates the enzymatic activity of cytoplasmic dynein.

13 orged between Lis1 and the microtubule motor cytoplasmic dynein.

14 amine the interaction of neurofilaments with cytoplasmic dynein.

15 s partially dependent on Aurora-A kinase and cytoplasmic dynein.

16 oposed to regulate the multiple functions of cytoplasmic dynein.

17 ormation through developmental regulation of cytoplasmic dynein.

18 forces on astral microtubules (MTs) through cytoplasmic dynein.

19 driven exclusively by the microtubule motor cytoplasmic dynein.

20 Cytoplasmic dynein 1 (dynein) is a minus end-directed mi

21 The cytoplasmic dynein 1 cargo binding domain is formed by f

22 Recent experiment showed that cytoplasmic dynein 1, a molecular motor responsible for

23 The cytoplasmic dynein-1 (dynein) motor plays a central role

24 Cytoplasmic dynein-1 (dynein-1) plays roles in mitosis a

25 t a previously unrecognized link between the cytoplasmic dynein-1 and IFT dynein-2 motors.

26 novel model by which stationary complexes of cytoplasmic dynein-1 are responsible for the shuttling o

27 Cytoplasmic dynein-1 binds dynactin and cargo adaptor pr

28 In human cells, cytoplasmic dynein-1 is essential for long-distance tran

29 DYNC1H1 encodes the heavy chain of cytoplasmic dynein-1, a 1.4-MDa motor complex that traff

30 gical and genetic manipulation, we show that cytoplasmic dynein-1, which localizes to the junction be

31 essential cofactor for the microtubule motor cytoplasmic dynein-1.

32 The microtubule motors kinesin-2 and cytoplasmic dynein 1b drive IFT particles (protein compl

33 re, we report that the retrograde IFT motor, cytoplasmic dynein 1b, is required in the cytoplasm for

34 d smaller groups are returned to the base by cytoplasmic dynein 1b.

35 nt away from the flagellar tip is powered by cytoplasmic dynein 1b/2.

36 his identifies potential novel components of cytoplasmic dynein 2 and furthermore provides fresh insi

37 nts IFT88, the kinesin-II subunit KIF3A, and cytoplasmic dynein 2 appeared compromised.

38 , a mammalian homologue of the Chlamydomonas cytoplasmic dynein 2 intermediate chain that also locali

39 both requiring the ciliary retrograde motor, cytoplasmic dynein 2, for ciliary exit.

40 Wdr34 gene encodes an intermediate chain of cytoplasmic dynein 2, the motor for retrograde intraflag

41 Cytoplasmic dynein-2 (dynein-2) performs intraflagellar

42 the light intermediate chain (D2LIC) of the cytoplasmic dynein-2 complex are essential for retrograd

43 Zebrafish lacking cytoplasmic dynein-2 function exhibited small eyes, kidn

44 Loss of cytoplasmic dynein-2 function resulted in a significant

45 the first time, that the dync2-i1 subunit of cytoplasmic dynein-2 is necessary for retrograde IFT.

46 y mutations in a new disease-producing gene, cytoplasmic dynein-2 light intermediate chain 1, DYNC2LI

47 e present the crystal structure of the human cytoplasmic dynein-2 motor bound to the ATP-hydrolysis t

48 nally, the ERG results indicate that loss of cytoplasmic dynein-2 reduces the photoreceptor light res

49 nd intermediate chain (dync2-i1) subunits of cytoplasmic dynein-2 were injected into zebrafish embryo

50 oreceptors lacking the retrograde IFT motor, cytoplasmic dynein-2.

51 ould be phenocopied by RNAi directed against cytoplasmic dynein, a known LIS1 interactor.

52 complex required for the in vivo function of cytoplasmic dynein, a microtubule (MT)-based motor.

53 1 and an interacting protein, NDEL1, bind to cytoplasmic dynein, a microtubule motor protein.

54 nhibitor nocodazole and by the inhibition of cytoplasmic dynein, a microtubule-associated motor prote

55 Cytoplasmic dynein, a microtubule-based motor protein, t

56 , Nudel/NudE, and dynactin are regulators of cytoplasmic dynein, a minus end-directed, microtubule (M

57 Cytoplasmic dynein, a minus-end-directed microtubule mot

58 Cytoplasmic dynein, a minus-end-directed microtubule mot

59 nding immunophilins that link the complex to cytoplasmic dynein, a molecular motor that processes alo

60 is central to the functional versatility of cytoplasmic dynein, a motor involved in intracellular tr

61 uggesting that dop is involved in regulating cytoplasmic dynein activity through direct or indirect m

62 Here we identify the cytoplasmic dynein adaptor Spindly as an additional comp

63 bunit forms two separate complexes, one with cytoplasmic dynein ("aggregation complex") and one with

64 In addition, cytoplasmic dynein also depended on EBA to track on most

65 antibody-Fab tag to mark the position of the cytoplasmic dynein amino-terminal tail domain, as it eme

66 Contacts between cytoplasmic dynein and astral microtubules (MTs) at the

67 r migration (INM) that is driven apically by cytoplasmic dynein and basally by the kinesin KIF1A, whi

68 Cytoplasmic dynein and dynactin interact to drive microt

69 Cytoplasmic dynein and dynactin participate in retrograd

70 The microtubule motor cytoplasmic dynein and its activator dynactin drive vesi

71 the trafficking of TYR and Pmel17 depends on cytoplasmic dynein and its interaction with the spectrin

72 The microtubule motor cytoplasmic dynein and its partner complex dynactin driv

73 implicated others [encoding neurofilaments, cytoplasmic dynein and its processivity factor dynactin,

74 Cytoplasmic dynein and kinesin are both microtubule-base

75 t, bidirectional capsid motility mediated by cytoplasmic dynein and kinesin during entry, whereas egr

76 Cytoplasmic dynein and kinesin I are both unidirectional

77 Cytoplasmic dynein and kinesin-1 are microtubule-based m

78 endosomes are transported bidirectionally by cytoplasmic dynein and kinesin-3, but how the movements

79 udEL are related proteins that interact with cytoplasmic dynein and LIS1.

80 1 in developing hair cells causes defects in cytoplasmic dynein and microtubule organization, resulti

81 precursor migration and the effects of LIS1, cytoplasmic dynein and myosin II inhibition.

82 In Aspergillus nidulans, cytoplasmic dynein and NUDF/LIS1 are found at the spindl

83 Dynactin links cytoplasmic dynein and other motors to cargo and is invo

84 in is a multiprotein complex that works with cytoplasmic dynein and other motors to support a wide ra

85 that kinesin-5 works in part by antagonizing cytoplasmic dynein and that these motor-driven forces fu

86 telomere attachment sites must be coupled to cytoplasmic dynein and the microtubule system to ensure

87 chain is a bona fide component of Drosophila cytoplasmic dynein and use P element excision to generat

88 ation activities associated with NuMA (i.e., cytoplasmic dynein) and HSET are not necessary for pole

89 d moved by microtubule motors (kinesin-1 and cytoplasmic dynein), and that binding of motors and move

90 sported by microtubule motors, kinesin-2 and cytoplasmic dynein, and an actin motor, myosin-V.

91 ransport machinery: specifically, kinesin-1, cytoplasmic dynein, and the dynein regulators Lis1 and d

92 Kinesin and cytoplasmic dynein are microtubule-based motor proteins

93 Using Saccharomyces cerevisiae cytoplasmic dynein as a model system, we mutagenized res

94 Our studies implicate cytoplasmic dynein as a more thermally tunable motor and

95 We identify Kinesin-1 and cytoplasmic dynein as major PrP(C) vesicle motor complex

96 are integral parts of the microtubule motor cytoplasmic dynein, as they directly associate with dyne

97 ts, but not control transcripts, recruit the cytoplasmic Dynein-associated co-factors Bicaudal D (Bic

98 A single major form of cytoplasmic dynein associates with membranous organelles

99 We find that PKA phosphorylates cytoplasmic dynein at a novel site in light intermediate

100 itotic checkpoint protein and the anchor for cytoplasmic dynein at mitotic kinetochores, though it is

101 ons to model the molecular motor function of cytoplasmic dynein at the single-molecule level.

102 Dynamitin is a commonly used inhibitor of cytoplasmic dynein-based motility in living cells.

103 rotubules are polarity sorted in the axon by cytoplasmic dynein but that additional factors are also

104 The velocity of mammalian cytoplasmic dynein, but not of mammalian kinesin-1, exhi

105 cellular functions of the microtubule motor cytoplasmic dynein, but the mechanism by which dynactin

106 in vivo evidence that distinct mutations in cytoplasmic dynein can either result in a pure sensory n

107 l trap, we were now able to demonstrate that cytoplasmic dynein can generate a discrete power stroke

108 tubule movements so that polarity sorting by cytoplasmic dynein can occur in a manner unimpeded by ot

109 ncoding the heavy chain subunit (DYNC1H1) of cytoplasmic dynein cause spinal muscular atrophy with lo

110 Converging studies suggest it requires cytoplasmic dynein, cell polarity genes, and microtubule

111 The microtubule motor protein cytoplasmic dynein clusters into a ring at the synapse,

112 at mutations in the minus-end-directed motor cytoplasmic dynein, completely block the increased DCVs

113 microtubule transport, the recombinant human cytoplasmic dynein complex is an active, microtubule min

114 n performed either with the native mammalian cytoplasmic dynein complex purified from tissue or, more

115 Here, we reconstitute a complete cytoplasmic dynein complex using recombinant human subun

116 ssed by disrupting the retrograde motor, the cytoplasmic dynein complex.

117 ays demonstrate that Bub3 interacts with the cytoplasmic dynein complex.

118 his nomenclature recognizes the two distinct cytoplasmic dynein complexes and has the flexibility to

119 n used in the literature for the subunits of cytoplasmic dynein complexes.

120 We find that Drosophila cytoplasmic dynein components are direct PKA phosphoryla

121 essing of tagged and truncated Dictyostelium cytoplasmic dynein constructs, we show that the heart of

122 TrkB) signaling endosomes are transported by cytoplasmic dynein containing the neuron-specific IC-1B

123 The heavy chain of cytoplasmic dynein contains four nucleotide-binding doma

124 minus-end directed microtubule motor protein cytoplasmic dynein contributes to many aspects of cell d

125 sitive to the addition of ATP, a hallmark of cytoplasmic dynein-dependent microtubule interactions.

126 Specifically, MPP+ increased cytoplasmic dynein-dependent retrograde FAT and reduced

127 crotubule-associated proteins (MAPs) but not cytoplasmic dynein-depleted MAPs.

128 n of kinesin-1 (KLC1) and the heavy chain of cytoplasmic dynein (DHC1) on vesicles.

129 o measure stall forces of both kinesin-1 and cytoplasmic dynein-driven lipid droplets in Drosophila e

130 r et al. and Hashimoto-Tane et al. show that cytoplasmic dynein drives microcluster centralization al

131 Cytoplasmic dynein drives the majority of minus end-dire

132 ei migrate basally during G1, apically using cytoplasmic dynein during G2, and undergo mitosis at the

133 Cytoplasmic dynein, dynactin, and pericentrin are all re

134 Single kinesin and cytoplasmic dynein-dynactin molecules fused with green-f

135 mutation in p150(Glued), a component of the cytoplasmic dynein/dynactin microtubule motor complex, r

136 of either kinesin-1 (kinesin heavy chain) or cytoplasmic dynein (dynein heavy chain) by RNA interfere

137 In contrast, cytoplasmic dynein efficiently navigates both axons and

138 , hexon, directly recruits the motor protein cytoplasmic dynein following virion entry.

139 plicated in targeting and binding cargoes to cytoplasmic dynein for retrograde or apical transport.

140 ond switch, depending on magnesium, converts cytoplasmic dynein from a nonprocessive to a processive

141 Bipolar spindle fusion was blocked when cytoplasmic dynein function was perturbed, suggesting a

142 Cytoplasmic dynein functions at several sites during mit

143 Cytoplasmic dynein functions in the checkpoint, apparent

144 ducts of the 6 kinesin gene family and the 1 cytoplasmic dynein gene.

145 Cytoplasmic dynein has been implicated in diverse mitoti

146 The microtubule-associated molecular motor, cytoplasmic dynein, has been implicated in the retrograd

147 A few small-molecule inhibitors of cytoplasmic dynein have been identified.

148 ioning in different systems, associates with cytoplasmic dynein heavy chain (DYNC1H1) in a Galphai-re

149 comprises different subunits assembled on a cytoplasmic dynein heavy chain 1 (DYNC1H1) dimer.

150 ant, c.917A>G, in DYNC1H1, which encodes the cytoplasmic dynein heavy chain 1 (here, novel refers to

151 to identify a nine base-pair deletion in the cytoplasmic dynein heavy chain 1 gene (Dync1h1) in this

152 The library was examined for inhibition of cytoplasmic dynein heavy chain and cell growth.

153 Partial depletion of cytoplasmic dynein heavy chain by RNA interference block

154 le-stimulated ATPase activity of recombinant cytoplasmic dynein heavy chain motor domain.

155 of CLIPA, green fluorescent protein-labeled cytoplasmic dynein heavy chain, p150(Glued) dynactin, an

156 ganelle movement by conventional kinesin and cytoplasmic dynein in a cell.

157 n hexon recruits the molecular motor protein cytoplasmic dynein in a pH-dependent manner, a function

158 FAK also associated with cytoplasmic dynein in a Ser-732 phosphorylation-dependen

159 Functional analysis of cytoplasmic dynein in Caenorhabditis elegans has reveale

160 RNA interference to investigate the role of cytoplasmic dynein in powering these transport events.

161 These immunophilins link to cytoplasmic dynein indirectly through the association of

162 at both Hook1 and Hook3 effectively activate cytoplasmic dynein, inducing longer run lengths and high

163 d a genomic region that contained DYNC2H1, a cytoplasmic dynein involved in retrograde transport in t

164 Cytoplasmic dynein is a 1.2-MDa multisubunit motor prote

165 Cytoplasmic dynein is a complex containing heavy chains

166 Cytoplasmic dynein is a dimeric AAA(+) motor protein tha

167 Cytoplasmic dynein is a dimeric motor that transports in

168 Cytoplasmic dynein is a homodimeric AAA+ motor that tran

169 Cytoplasmic dynein is a homodimeric microtubule (MT) mot

170 Cytoplasmic dynein is a large minus end-directed motor c

171 Cytoplasmic dynein is a large multisubunit complex invol

172 Cytoplasmic dynein is a large multisubunit motor protein

173 Cytoplasmic dynein is a large, microtubule-dependent mol

174 Cytoplasmic dynein is a microtubule motor involved in ca

175 Cytoplasmic dynein is a microtubule-based molecular moto

176 Cytoplasmic dynein is a microtubule-based motor protein

177 Cytoplasmic dynein is a microtubule-based motor protein

178 Cytoplasmic dynein is a microtubule-based motor required

179 Cytoplasmic dynein is a minus-end-directed microtubule m

180 Cytoplasmic dynein is a molecular motor responsible for

181 Cytoplasmic dynein is a molecular motor that transports

182 Cytoplasmic dynein is a motor protein that walks along m

183 Cytoplasmic dynein is a multisubunit microtubule motor c

184 in vivo and in vitro, we found evidence that cytoplasmic dynein is active during minus- and plus-end

185 Cytoplasmic dynein is an abundant kinetochore protein wh

186 Here, we report that the stalk shaft of rat cytoplasmic dynein is an antiparallel alpha-helical coil

187 Cytoplasmic dynein is an approximately 1.4 MDa multi-pro

188 Cytoplasmic dynein is an enormous minus end-directed mic

189 The functional diversity of cytoplasmic dynein is in part attributed to multiple int

190 Cytoplasmic dynein is involved in a multitude of essenti

191 Cytoplasmic dynein is involved in a wide range of cellul

192 In higher eukaryotes, cytoplasmic dynein is involved in silencing the SAC by r

193 endosomes from the axon to the cell body by cytoplasmic dynein is necessary for axonal and neuronal

194 Cytoplasmic dynein is particularly important for neurons

195 Whereas cytoplasmic dynein is primarily known as a minus-end-dir

196 Previous studies have suggested that cytoplasmic dynein is required for efficient neurofilame

197 Furthermore, we found that cytoplasmic dynein is required for the spindle pole accu

198 Cytoplasmic dynein is responsible for a wide range of ce

199 Cytoplasmic dynein is responsible for many aspects of ce

200 The molecular motor cytoplasmic dynein is responsible for most minus-end-dir

201 The minus end-directed microtubule motor cytoplasmic dynein is responsible for the intracellular

202 Cytoplasmic dynein is responsible for transport of sever

203 Cytoplasmic dynein is the main retrograde motor in all e

204 Cytoplasmic dynein is the major microtubule minus end-di

205 Cytoplasmic dynein is the major microtubule minus-end-di

206 Cytoplasmic dynein is the major minus end-directed micro

207 Cytoplasmic dynein is the major motor protein responsibl

208 Cytoplasmic dynein is the molecular motor responsible fo

209 We have previously demonstrated that cytoplasmic dynein is the motor involved in the perinucl

210 Cytoplasmic dynein is the motor protein responsible for

211 Cytoplasmic dynein is the multisubunit motor protein for

212 Cytoplasmic dynein is the multisubunit protein complex r

213 Cytoplasmic dynein is the predominant minus-end-directed

214 Cytoplasmic dynein is the primary minus-end-directed mic

215 Cytoplasmic dynein is the primary molecular motor respon

216 Cytoplasmic dynein is well characterized as an organelle

217 Previously, the 8-kDa cytoplasmic dynein light chain (LC8) was demonstrated to

218 ture of isoform 1 of the mouse Roadblock/LC7 cytoplasmic dynein light chain (robl1_mouse) by NMR spec

219 nal kinesin, reductions in the levels of the cytoplasmic dynein light chain Tctex type 3 subunit were

220 In this paper, we show that the cytoplasmic dynein light chain Tctex-1 plays a key role

221 studies, we show that in rodents Tctex-1, a cytoplasmic dynein light chain, is selectively enriched

222 Dominant mutations in cytoplasmic dynein (Loa or Cra) have been reported to pr

223 MTOC, in which the minus end-directed motor cytoplasmic dynein, localized at the synapse through an

224 This is especially important for mammalian cytoplasmic dyneins, many subunits of which are encoded

225 is a highly conserved protein necessary for cytoplasmic dynein-mediated nuclear migration in Aspergi

226 say was used to evaluate the hypothesis that cytoplasmic dynein mediates AAV interaction with microtu

227 Cytoplasmic dynein mediates retrograde transport in axon

228 Cytoplasmic dynein mediates spindle orientation from the

229 Cytoplasmic dynein mediates spindle positioning in buddi

230 Recently, an x-ray structure of the murine cytoplasmic dynein microtubule binding domain (MTBD) in

231 a mutation in dhc-1, the heavy chain of the cytoplasmic dynein minus-end directed microtubule motor,

232 along microtubules is powered by kinesin and cytoplasmic dynein molecular motors.

233 Cytoplasmic dynein motility along microtubules is critic

234 ight chain LC8 is an integral subunit of the cytoplasmic dynein motor complex that binds directly to

235 Tctex-1, a light-chain component of the cytoplasmic dynein motor complex, can function independe

236 We show that a single cytoplasmic dynein motor frequently transitions into an

237 The cytoplasmic dynein motor generates pulling forces to cen

238 ion of a specific role for these proteins in cytoplasmic dynein motor regulation has remained elusive

239 lization to elucidate relative kinesin-1 and cytoplasmic dynein motor subunit composition of individu

240 Dynactin is an essential part of the cytoplasmic dynein motor that enhances motor processivit

241 , dynactin, is an essential component of the cytoplasmic dynein motor.

242 Our data also suggest kinesin-1 and cytoplasmic dynein motors assemble in stable mixtures on

243 re under the influence of forces mediated by cytoplasmic dynein motors associated with the cell corte

244 MTs to test the hypothesis that immobilized cytoplasmic dynein motors transport short MTs with their

245 Metazoan cytoplasmic dynein moves processively along microtubules

246 Cytoplasmic dynein moves processively along microtubules

247 Our results suggest that cytoplasmic dynein moves processively through the coordi

248 microtubules in the cell periphery, whereas cytoplasmic dynein moves to the minus ends in the cell c

249 We report the crystal structure of the mouse cytoplasmic dynein MTBD and a portion of the coiled coil

250 single molecule motility properties of yeast cytoplasmic dynein mutants bearing mutations that preven

251 (chromokinesin and Eg5) and minus-directed (cytoplasmic dynein oligomers) motors walking on microtub

252 litates the localization of Mcp5 and that of cytoplasmic dynein on the membrane.

253 y distribution of melanosomes transported by cytoplasmic dynein or kinesin-2 under conditions of aggr

254 terfering RNA (siRNA)-mediated inhibition of cytoplasmic dynein or the kinesin 1 heavy chain KIF5B de

255 Proteins in the cytoplasmic dynein pathway accumulate at the microtubule

256 Cytoplasmic dynein performs multiple cellular tasks but

257 phenotype than the control, indicating that cytoplasmic dynein plays a role in chromosome segregatio

258 Cytoplasmic dynein plays important roles in membrane tra

259 During mitosis, the motor molecule cytoplasmic dynein plays key direct and indirect roles i

260 Cytoplasmic dynein powers intracellular movement of carg

261 In axons of PNS neurons, cytoplasmic dynein provides force for retrograde movemen

262 e compelling evidence that the motor protein cytoplasmic dynein provides the necessary force for micr

263 The AAA+ ATPase motor cytoplasmic dynein regulates ciliary trafficking, mitoti

264 erkinetic nuclear migration, consistent with cytoplasmic dynein regulation.

265 We propose that the cytoplasmic dynein regulators are a critical component o

266 It is specifically blocked by RNAi for the cytoplasmic dynein regulators LIS1 and NudE/L (Nde1/Ndel

267 The cytoplasmic dynein regulatory factor Lis1, which induces

268 Kinesin-1 and cytoplasmic dynein require each other for bidirectional

269 The spindle pole localization of cytoplasmic dynein requires the function of the anaphase

270 motor axons are kinesin-1 (anterograde) and cytoplasmic dynein (retrograde), and interestingly that

271 Regulation of cytoplasmic dynein's motor activity is essential for div

272 cture we are able to draw new conclusions on cytoplasmic dynein's stepping mechanism.

273 motor, the function of NUDF is important for cytoplasmic dynein's targeting to the spindle poles.

274 In contrast, the velocity of yeast cytoplasmic dynein showed a break from Arrhenius behavio

275 RNAi directed against cytoplasmic dynein specifically inhibited nuclear moveme

276 We propose names for the mammalian cytoplasmic dynein subunit genes and proteins that refle

277 ctions in levels of conventional kinesin and cytoplasmic dynein subunits were recapitulated in a rat

278 is a highly conserved light-chain subunit of cytoplasmic dynein that interacts with a wide variety of

279 Cytoplasmic dynein, the 1.2 MDa motor driving minus-end-

280 an interaction between the microtubule motor cytoplasmic dynein, the adenomatous polyposis coli tumor

281 contain a large number of kinesins but lack cytoplasmic dynein, the foremost processive retrograde t

282 Cytoplasmic dynein, the major motor driving retrograde a

283 orted to regulate the mechanical behavior of cytoplasmic dynein, the primary minus-end-directed micro

284 The ability of cytoplasmic dynein to recognize such diverse forms of ca

285 binding to Trk initiates the recruitment of cytoplasmic dynein to signaling endosomes through ERK1/2

286 es attachment of the microtubule-based motor cytoplasmic dynein to the cortex, where it exerts a pull

287 nuclear INT complex promotes recruitment of cytoplasmic dynein to the NE, possibly via a mechanism i

288 pAR63, nearly eliminates the localization of cytoplasmic dynein to the spindle poles, but it has no a

289 To do this, we fused the MTBD of mouse cytoplasmic dynein, together with 12-36 residues of its

290 Cytoplasmic dynein transports cargoes for a variety of c

291 Cytoplasmic dynein transports membranous cargoes along m

292 Cytoplasmic dynein transports various cellular cargoes i

293 The minus end-directed microtubule motor cytoplasmic dynein transports various cellular cargoes,

294 s proplatelet elongation and is dependent on cytoplasmic dynein under static and physiological shear

295 The microtubule motor cytoplasmic dynein was a critical part of this coalescin

296 In view of new results on cytoplasmic dynein, we attempt to rationalize how these

297 s varying DNA sequences, and to myosin V and cytoplasmic dynein, which may advance by variable increm

298 sitioning, are mediated by the motor protein cytoplasmic dynein, which produces force on the microtub

299 We also predict that acute inhibition of cytoplasmic dynein will disrupt the polarity sorting of

300 oups of motor proteins, such as kinesins and cytoplasmic dynein, work together to ensure the supply a