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1 no acids 112 and 164 apparently required for cytoplasmic retention.
2 cytochalasin B and nocodazole did not affect cytoplasmic retention.
3 xport and by an uncharacterized mechanism of cytoplasmic retention.
4 wever, homodimerization was not required for cytoplasmic retention.
5 with p40 is necessary but not sufficient for cytoplasmic retention.
6 -terminal coiled-coil domain responsible for cytoplasmic retention.
7 nd cytoplasm and ultimately resulting in its cytoplasmic retention.
8 es act additively to fine-tune signaling via cytoplasmic retention.
9 127, which results in YAP 14-3-3 binding and cytoplasmic retention.
10 noubiquitination masks its NLS, resulting in cytoplasmic retention.
11 ics the monoubiquitinated enzyme resulted in cytoplasmic retention.
12 the cell-cycle inhibitor p27, promoting its cytoplasmic retention.
13 leads Smad1 alternatively to degradation or cytoplasmic retention.
14 ed BR transcription factors, largely through cytoplasmic retention.
15 ct maternal mRNA by MSY2 is required for its cytoplasmic retention.
16 rom regulatory mechanisms that control their cytoplasmic retention.
17 to exert some redundant effect on Ci such as cytoplasmic retention.
20 onformational motif in AID that dictates its cytoplasmic retention and demonstrate that the translati
21 o(107), respectively, in HA-Myb1 resulted in cytoplasmic retention and elevated nuclear translocation
22 a J-domain-dependent fashion and led to the cytoplasmic retention and enhanced stability of IkappaB.
23 inase cascade that leads to phosphorylation, cytoplasmic retention and functional inactivation of the
25 ed YAP1/SMAD2 interaction and leads to SMAD2 cytoplasmic retention and inefficient transcription of T
26 d by dAkt upon insulin treatment, leading to cytoplasmic retention and inhibition of its transcriptio
27 the death domain alone is not sufficient for cytoplasmic retention and instead functions only in conj
28 nucleus through a combined disruption of its cytoplasmic retention and its nuclear export, this oncog
29 ino acids in extramembrane domains represent cytoplasmic retention and membrane translocation forces,
30 unctional NES is required for both efficient cytoplasmic retention and post-induction control of c-Re
31 ntain more than one region that functions as cytoplasmic retention and/or nuclear export sequences.
33 clear localization signal (NLS) promotes its cytoplasmic retention, and cytoplasmic Skp2 enhances cel
34 or complex are tightly regulated through its cytoplasmic retention by an ankyrin-rich inhibitory prot
37 istinguished JNK-2 as responsible for NFATc2 cytoplasmic retention by PEDF and JNK-1 and JNK-2 as med
38 transcription factor Smad2 is released from cytoplasmic retention by TGFbeta receptor-mediated phosp
40 results elucidate the molecular basis of AID cytoplasmic retention, define its functional relevance a
41 y two distinct activities: it functions as a cytoplasmic retention determinant and an Asi-dependent d
42 C-terminal domain that is distinct from the cytoplasmic retention domain, (ii) interference with tra
45 nt susceptibility to inhibition of import by cytoplasmic retention factor SARA (Smad anchor for recep
47 present a crystal structure of Bag6 and its cytoplasmic retention factor TRC35, revealing that TRC35
48 consensus sites is not necessary for Ace2's cytoplasmic retention, indicating that these mechanisms
49 the cytoplasm past the MBT, indicating that cytoplasmic retention is a phosphorylation dependent pro
51 lized p53 in REF52/N-myc cells suggests that cytoplasmic retention may help to inactivate the growth-
52 ombine to suggest that monocytic cells use a cytoplasmic retention mechanism to control A3A and avert
53 dicate that whereas positive charges promote cytoplasmic retention, negative charges promote transloc
54 accumulation involves neither a release from cytoplasmic retention nor an increase in Smad2 import ra
55 endogenous conditions, GI stabilization and cytoplasmic retention occurs naturally through a LOV dom
56 e-induced autophagy combined with the longer cytoplasmic retention of ARpolyQ bound to Bicalutamide.
61 demonstrate that Tax is able to override the cytoplasmic retention of c-Rel by 1kappaBbeta in transie
62 he human thrombin receptor revealed that the cytoplasmic retention of CCR2A was due to its terminal c
65 s nuclear translocation, suggesting that the cytoplasmic retention of Ci155 may also depend on NLS ma
67 yclin B1, whereas C53 deficiency led to more cytoplasmic retention of cyclin B1, suggesting that C53
68 trate that the ability of MKP-3 to cause the cytoplasmic retention of ERK2 requires both a functional
71 l surface, and loss of LLG1 function induces cytoplasmic retention of FER, consistent with transport
74 gen sources controls the phosphorylation and cytoplasmic retention of Gln3 via the target of rapamyci
75 role of the IkappaBbeta insert in regulating cytoplasmic retention of IkappaBbeta.NF-kappaB complexes
77 he interaction of NP with F-actin causes the cytoplasmic retention of influenza virus ribonucleoprote
80 e nuclear levels of NF-kappaB indicates that cytoplasmic retention of NF-kappaB may be compensated fo
84 nly reveal the molecular mechanism involving cytoplasmic retention of NPMc but also suggest cytoplasm
85 agent of cervical cancer, enhanced both the cytoplasmic retention of p27 and the migration of human
86 sequestration in yeast, we demonstrate that cytoplasmic retention of p65 (also called RelA) by Ikapp
88 ation from the reference OCTN2, with diffuse cytoplasmic retention of Phe17Leu, in contrast to refere
89 nistically, we determined that YAP1 mediates cytoplasmic retention of phosphorylated SMAD3 and suppre
91 f negative residues working in opposition to cytoplasmic retention of positive residues, thus allowin
92 Furthermore, our results showed that the cytoplasmic retention of RARgamma was due to the presenc
94 as an inhibitor of Rel/NF-kappaB activity by cytoplasmic retention of Rel/NF-kappaB complexes, like o
100 fic deletion of FLCN relieves mTOR-dependent cytoplasmic retention of TFE3, leading to direct inducti
101 beta (TGF beta) induced phosphorylation and cytoplasmic retention of the Forkhead factor FKHRL1, whi
102 lassically, NF-kappaB activity is limited by cytoplasmic retention of the NF-kappaB dimer through bin
103 s, continuous nuclear export is required for cytoplasmic retention of the v-Rel-IkappaB alpha complex
104 that activation of the PI3K pathway mediated cytoplasmic retention of the Wilms tumor (WTI) protein,
105 n the PABPC RRMs, thereby ensuring efficient cytoplasmic retention of this protein in normal cells.
106 markers of lysosome function, accompanied by cytoplasmic retention of transcription factor EB (TFEB),
110 d to be mediated through phosphorylation and cytoplasmic retention of YAP and reduced expression of d
114 tential of negative residues in favor of the cytoplasmic retention potential of positive residues, th
115 ely charged amino acids, thus increasing the cytoplasmic retention potential of positively charged am
116 e results imply that BRAP2 may function as a cytoplasmic retention protein and play a role in regulat
117 M phase, cyclin B1 is phosphorylated in the cytoplasmic retention sequence (CRS), which is required
118 show here that the previously characterized cytoplasmic retention sequence of Cyclin B1, responsible
119 omain sequences of RGS6 proteins function as cytoplasmic retention sequences to prevent their nuclear
120 rminus of APOBEC-1 with characteristics of a cytoplasmic retention signal (CRS) or a nuclear export s
121 this specialized property of hA3G is a novel cytoplasmic retention signal (CRS) that is necessary and
124 cation of the carboxyl tail indicated that a cytoplasmic retention signal(s) was located between resi
125 s phosphorylation within a region called the cytoplasmic retention signal, which also contains a nucl
126 understand the mechanism responsible for its cytoplasmic retention, studies were undertaken to determ
127 in both Ad12- and Ad5-transformed cells via cytoplasmic retention, though only Ad12-transformed cell
128 C4 has been proposed to be important for its cytoplasmic retention, we find this interaction to be in
129 s interaction with 14-3-3beta leading to XLF cytoplasmic retention, where cytosolic XLF is subsequent
130 junctions to induce Yap phosphorylation and cytoplasmic retention, which drive cell differentiation.
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