ライフサイエンスコーパス: cytoplasmic tail

1 smic proteins talin and kindlin to the beta3 cytoplasmic tail.

2 e pore-lining S6 helix connects to a helical cytoplasmic tail.

3 or tyrosine-based switch motifs in the NTB-A cytoplasmic tail.

4 sical interaction between Mcc and the Vangl2 cytoplasmic tail.

5 o the parasite actomyosin system through its cytoplasmic tail.

6 l degradation owing to the truncation of its cytoplasmic tail.

7 hat cortactin binds directly to the cadherin cytoplasmic tail.

8 the presence of the distal region of the M2 cytoplasmic tail.

9 mains (TMDs) and a highly charged C-terminal cytoplasmic tail.

10 erved YxxO trafficking motif in the envelope cytoplasmic tail.

11 ons of two critical leucines on the receptor cytoplasmic tail.

12 need for signal transduction by the neurexin cytoplasmic tail.

13 s-presentation by MHC-I containing the HLA-C cytoplasmic tail.

14 F, and transmembrane domains, as well as the cytoplasmic tail.

15 se A-mediated phosphorylation of B2AR on the cytoplasmic tail.

16 th p120-catenin and beta-catenin through its cytoplasmic tail.

17 sequence in the receptor's carboxyl-terminal cytoplasmic tail.

18 ecruits Gag by a process that depends on its cytoplasmic tail.

19 kinase domain but suppressing it through its cytoplasmic tail.

20 ular switch in the amyloid precursor protein cytoplasmic tail.

21 fluenced by the presence of a truncated CD1d cytoplasmic tail.

22 e transmembrane (TM) domain and a 20-residue cytoplasmic tail.

23 ) domain, all transmembrane domains, and the cytoplasmic tail.

24 omplex, and compromised by removing the K(b) cytoplasmic tail.

25 rcholesterolemia (ARH), which binds the LDLR cytoplasmic tail.

26 e extracellular domain of beta1, but not its cytoplasmic tail.

27 ith the CK2-binding domain at the end of its cytoplasmic tail.

28 These effects required the full CD1d cytoplasmic tail.

29 ylation of the vascular endothelial-cadherin cytoplasmic tail.

30 immediate stop codon, resulting in a shorter cytoplasmic tail.

31 egulated by a critical tyrosine motif in the cytoplasmic tail.

32 obic C terminus containing a TM domain and a cytoplasmic tail.

33 ifferent binding domains within the integrin cytoplasmic tail.

34 artner of a platelet-specific alpha-integrin cytoplasmic tail.

35 tibodies), the transmembrane domain, and the cytoplasmic tail.

36 indlin-3 through interactions with the beta3 cytoplasmic tail.

37 f tyrosine residues embedded in ITIMs of the cytoplasmic tail.

38 tes Pro(1146) for Ser in the integrin alphaM cytoplasmic tail.

39 a and possible compensatory mutations in the cytoplasmic tail.

40 utant without the afadin-binding site in its cytoplasmic tail.

41 transmembrane region, and a short conserved cytoplasmic tail.

42 d proximal to the B30.2 domain in the BTN3A1 cytoplasmic tail.

43 and p120-binding domains within the cadherin cytoplasmic tail.

44 ary complex with the Talin and beta-integrin cytoplasmic tails.

45 f talin and kindlin to integrin beta-subunit cytoplasmic tails.

46 n activator talin and is present at integrin cytoplasmic tails.

47 in-containing tyrosine phosphatases to their cytoplasmic tails.

48 tutions distinguish the Patr-AL and HLA-A*02 cytoplasmic tails.

49 is regulated by binding of proteins to their cytoplasmic tails.

50 noglobulin-like receptor, three domain, long cytoplasmic tail, 2 (KIR3DL2); interleukin 4 (IL4); and

51 virus M2 ion channel protein contains in its cytoplasmic tail a membrane-proximal amphipathic helix t

52 Elimination of its cytoplasmic tail abolished the interaction of Slamf1 wit

53 x32, the expression of cell surface-targeted cytoplasmic tail alone is sufficient to enhance the size

54 his effect is mediated by the integrin beta1 cytoplasmic tail and does not entail beta1 heterodimeriz

55 ermining talin binding to the beta3-integrin cytoplasmic tail and inducing a kink in the transmembran

56 of a clade B virus Env, which lacks only the cytoplasmic tail and is stabilized by the broadly neutra

57 that interaction between the integrin beta1 cytoplasmic tail and kindlin-2, a member of a family of

58 a1-integrin by restricting the motion of the cytoplasmic tail and reducing the entropic barrier for t

59 Interactions between the glycoprotein cytoplasmic tail and the matrix domain of Gag are though

60 n-2 but not polysialylated when it lacks its cytoplasmic tail and transmembrane region and is secrete

61 h intracellular interactions at the integrin cytoplasmic tails and through integrin-ligand binding.

62 vascular endothelial cadherin (VE-cadherin) cytoplasmic tail, and direct FAK phosphorylation of beta

63 in the membrane-proximal region of the GluA2 cytoplasmic tail, and suggest a distinct model for the r

64 in and kindlin-2 interact with integrin beta cytoplasmic tails, and they function in concert to induc

65 beta-subunits are well separated with their cytoplasmic tails approximately 8 nm apart.

66 directional signal transducers because their cytoplasmic tails are docking sites for cytoskeletal and

67 ereas the carboxyl termini, often called the cytoplasmic tails, are highly divergent.

68 The MUC1 cytoplasmic tail associated with TLR5 in all cells teste

69 In resting T cells, the CD3epsilon cytoplasmic tail associates with the plasma membrane via

70 GF-alpha induced phosphorylation of the MUC1 cytoplasmic tail at the Y46EKV sequence and increased as

71 Kindlins are integrin cytoplasmic tail binding partners and are essential for

72 n between ADAP and 2 essential integrin-beta cytoplasmic tail-binding proteins involved in alphaIIbbe

73 of a yeast two-hybrid screen for the MT1-MMP cytoplasmic tail-binding proteins, we identify here a no

74 SYG-1 cytoplasmic tail binds to the WRC using a consensus WRC

75 not affect its binding to the integrin beta3 cytoplasmic tail, but combined biochemical and NMR analy

76 7 activation involves phosphorylation of its cytoplasmic tail by mitogen-activated protein kinase (MA

77 embrane to induce phosphorylation of the CD3 cytoplasmic tails by incompletely understood mechanisms.

78 We further show that the presence of a cytoplasmic tail (c-tail) is indispensible, and identifi

79 n-like domain, a transmembrane domain, and a cytoplasmic tail containing a YXX sorting motif.

80 cells and signals through either a long (L) cytoplasmic tail containing immune receptor tyrosine bas

81 ersions of their FcgammaRII by switching the cytoplasmic tails containing the ITAM/ITIM motifs, leavi

82 a/DRbeta dimer most other amino acids in the cytoplasmic tail could be substituted for alanine with m

83 te the effects of functional properties of F cytoplasmic tail (CT) amino acids on virus replication a

84 ry syncytial virus (HRSV) fusion (F) protein cytoplasmic tail (CT) and matrix (M) protein are key med

85 ES is mediated by an interaction between its cytoplasmic tail (CT) and N.

86 nt study, we modified RSV F by replacing its cytoplasmic tail (CT) domain or its CT and transmembrane

87 duced by deleting the transmembrane (TM) and cytoplasmic tail (CT) domains and appending a glycosylph

88 shows anti-inflammatory properties, and its cytoplasmic tail (CT) interacts with transcription facto

89 Truncation of the cytoplasmic tail (CT) of Env abrogated Gag's ability to

90 The highly conserved long cytoplasmic tail (CT) of Env is required in a cell type-

91 h interactions with host cell machinery, the cytoplasmic tail (CT) of F is a likely interactive domai

92 extracellular domain of rabies fused to the cytoplasmic tail (CT) of gp41 and pseudotyped lentiviral

93 The cytoplasmic tail (ct) of RAGE is essential for RAGE liga

94 teractions between the uncleaved Gag and the cytoplasmic tail (CT) of the Env protein.

95 mutant with truncation mutation in the gp41 cytoplasmic tail (CT) which is unable to modulate Env fu

96 gi and this step requires interaction of its cytoplasmic tail (CT) with a protein that has not been i

97 eptor (CD21=CR), a mutant lacking the entire cytoplasmic tail (CT), and a control vector (NEO) were s

98 s homologous gp41 envelope glycoprotein (GP) cytoplasmic tail (CT), we created chimeric RVG/HIV-1gp41

99 -muscle myosin IIA, a motor protein, via the cytoplasmic tail (CT).

100 irtue of an interaction with the Env protein cytoplasmic tails (CTs).

101 Mutations within the cytoplasmic tail (cytotail) of herpes simplex virus 1 (H

102 that compared with the full-length Cx32, the cytoplasmic tail-deleted Cx32 is assembled into small ga

103 ficant increase in IgM ligand binding in the cytoplasmic tail-deletion mutant, 2) enhanced cap format

104 tsO45 with either the native G tail (G) or a cytoplasmic tail derived from the chicken AE1-4 anion ex

105 Deletion or replacement of the FcRn cytoplasmic tail does not prevent diversion of trafficki

106 amino acids (+3 leucine) or by deleting the cytoplasmic tail domain (CTD) in the +1 leucine backgrou

107 These findings indicate that the cytoplasmic tail domain of BHA is important for efficien

108 ecombinant influenza B virus lacking the BHA cytoplasmic tail domain.

109 However, when the cytoplasmic tail domains (CTDs) in the Env constructs we

110 mutation that truncated most of the tetherin cytoplasmic tail early in the Feliformia lineage (19 of

111 a membrane-bound Env trimer with a truncated cytoplasmic tail (EnvDeltaCT).

112 istically, P1146S substitution in the alphaM cytoplasmic tail generates a noncanonical 14-3-3zeta bin

113 ot PHV, harbor elements in their 142-residue cytoplasmic tails (GnTs) that inhibit RIG-I/MAVS/TBK1-TR

114 Truncation of their cytoplasmic tail has little effect on membrane fusion, b

115 The beta1 cytoplasmic tail has two NPxY motifs that mediate functi

116 Binding of talin head domain to beta cytoplasmic tails has been characterized extensively, bu

117 plasmic tail of Vpu, specifically within the cytoplasmic tail hinge region, were required for modulat

118 essing the membrane-bound ADAM15 without its cytoplasmic tail, however, lost this anti-apoptotic prop

119 These results demonstrate the role of the F cytoplasmic tail in accumulation of structural component

120 To understand the role of this cytoplasmic tail in infectious virus production, we used

121 long-term culture of a virus lacking the BHA cytoplasmic tail in Madin-Darby canine kidney (MDCK) cel

122 ic cleavage of the murine leukemia virus Env cytoplasmic tail in pseudotyped virions.

123 ete conformational changes in the C-terminal cytoplasmic tail in response to changes in cytoplasmic C

124 onstrated proteoforms of ADAM8 that lack the cytoplasmic tail in the supernatant.

125 Moreover, the beta1 cytoplasmic tail, in the context of the adjacent transme

126 tifs (FxNPxY or HIC) encoded within the LDLR cytoplasmic tail, indicating an additional internalizati

127 idues where replaced with those of the beta1 cytoplasmic tail induced only small chemical shift pertu

128 ed that a dileucine-like motif in the DRbeta cytoplasmic tail influences the efficiency of co-localiz

129 se results suggest that PC1, via its cleaved cytoplasmic tail, integrates signaling inputs from EGFR

130 The cytoplasmic tail is apparently crucial for internalizati

131 The MUC1 cytoplasmic tail is known to activate multiple signaling

132 The short cytoplasmic tail is lacking in any known signaling motif

133 fected by the origin of F, suggesting that F cytoplasmic tail is not involved in intracellular moveme

134 oprecipitates with ILK in cells and that its cytoplasmic tail is required for this interaction.

135 splay a number of unique features, including cytoplasmic tails lacking characteristic SLAMF signaling

136 he viral transmembrane envelope glycoprotein cytoplasmic tail leads in pig-tailed macaques to a uniqu

137 al regulation of the Thr(567) in the MT1-MMP cytoplasmic tail may function as a regulatory mechanism

138 Knockin mice with CD28 cytoplasmic tail mutations that abrogate Vav signaling (

139 TgAMA1 cytoplasmic tail mutations that disrupt ALD binding in v

140 ture, an S6 activation gate position and the cytoplasmic tail "neck", are central to BacNaV gating.

141 ding domains for signaling proteins in their cytoplasmic tails, nonetheless also transduce signals to

142 ith a knockin mutation that ablates the NRP1 cytoplasmic tail (Nrp1(cyto)) have normal angiogenesis b

143 rus hemagglutinin (BHA) contains a predicted cytoplasmic tail of 10 amino acids that are highly conse

144 ows the importance of single residues in the cytoplasmic tail of a Golgi-resident protein for localiz

145 ng partner, p120-catenin (p120ctn), with the cytoplasmic tail of apical mucin-1 (MUC1-CT) represent i

146 ion of the DXXLL-motif sequence DISLL in the cytoplasmic tail of BACE1.

147 The cytoplasmic tail of beta-integrin (PAT-3) is associated

148 tinin competes with talin for binding to the cytoplasmic tail of beta3-integrin, whereas it cooperate

149 Furthermore, p120-catenin binds to the cytoplasmic tail of cadherin and stabilizes it at the pl

150 root of the tip link is mainly formed by the cytoplasmic tail of cadherin23 and its actin-anchoring p

151 and cargo-tethering protein, recognized the cytoplasmic tail of CD147 to help sort it and CD98 into

152 r of beta2 integrins that interacts with the cytoplasmic tail of CD18 and is crucial for induction of

153 Two sites within the cytoplasmic tail of CD28, a YMNM sequence that recruits

154 ual CD44 fragment, liberating the C-terminal cytoplasmic tail of CD44.

155 n adherens junctions, beta-catenin links the cytoplasmic tail of classical cadherins to the F-actin-b

156 Deletion of the cytoplasmic tail of CR2, which in an epithelial cell int

157 terminus to active GTP-Rab8, as well as the cytoplasmic tail of CTLA-4.

158 The C-terminal cytoplasmic tail of Ctr1 is a 13-residue peptide harbori

159 Our results suggest that the cytoplasmic tail of Cx32 is not required to initiate the

160 Our findings suggest that the cytoplasmic tail of Cx32 may be involved in regulating t

161 We have explored the role of the cytoplasmic tail of Cx32, a Cx expressed in polarized an

162 rosine-based targeting signal present in the cytoplasmic tail of DMbeta.

163 In epithelial cells, the cytoplasmic tail of E-cadherin forms a dynamic complex w

164 ith the retrieval mutant, replacement of the cytoplasmic tail of E3/19K allowed only limited transpor

165 Interestingly, the cytoplasmic tail of E3/49K contains two potential sortin

166 determined by distinct motifs present in the cytoplasmic tail of each cargo, with Wls using tandem Ph

167 x (MA) domain of the Gag polyprotein and the cytoplasmic tail of Env are central players in the proce

168 mbly and the matrix domain accommodating the cytoplasmic tail of Env in the Gag lattice.

169 y distinct but complementary roles, with the cytoplasmic tail of Env responsible for directing Env to

170 itionally, we found that truncating the long cytoplasmic tail of Env restores incorporation of Env in

171 e rearrangements result in truncation of the cytoplasmic tail of EPOR at residues similar to those mu

172 of suspected gamma-COP-binding motifs in the cytoplasmic tail of ERManI was sufficient to disrupt the

173 Whereas the two cysteines in the cytoplasmic tail of HA contain only palmitate, stearate

174 a lattice capable of accommodating the long cytoplasmic tail of HIV-1 Env; in the absence of MA trim

175 Third, deletion of the cytoplasmic tail of HIV-1 gp41 dramatically enhanced the

176 The C-terminal cytoplasmic tail of human PC2 (HPC2 Cterm) is important

177 We show that the cytoplasmic tail of IAV M2 interacts directly with the e

178 The highly conserved cytoplasmic tail of influenza virus glycoprotein hemaggl

179 se mutation from methionine to lysine in the cytoplasmic tail of Kcc1 impairs phosphorylation of adja

180 Proteins binding to the cytoplasmic tail of L-selectin regulate L-selectin funct

181 put is dependent on this interaction and the cytoplasmic tail of L-selectin.

182 ic calcium-binding protein calmodulin to the cytoplasmic tail of L-selectin.

183 a premature stop codon deleting most of the cytoplasmic tail of LAT, including the critical tyrosine

184 A, and recovery from each, we found that the cytoplasmic tail of M6PR causes the recruitment of AP-1

185 Herein we report that the intracellular cytoplasmic tail of Met has evolved to harbor a tandem p

186 p11 directly binds to the cytoplasmic tail of metabotropic glutamate receptor 5 (m

187 es show that islet formation is based on the cytoplasmic tail of MT1-MMP and its ability to bind the

188 Accumulating evidence shows that the cytoplasmic tail of MT1-MMP is subjected to phosphorylat

189 neurons with and without a peptide from the cytoplasmic tail of NaVbeta4 (the beta4 peptide), which

190 eported that tyrosine phosphorylation of the cytoplasmic tail of nephrin facilitates recruitment of N

191 ility of ProSAP2/Shank3 to interact with the cytoplasmic tail of Neuroligins functions to coordinate

192 We show that the cytoplasmic tail of PAT-3 binds to full-length UNC-112 a

193 Replacing the cytoplasmic tail of Patr-AL with that of HLA-A*02 increa

194 Although the C-terminal cytoplasmic tail of PC2 has been shown to contain a Ca(2

195 n which parts of the N and C terminus of the cytoplasmic tail of PC7 were deleted, and chimeric prote

196 In resting platelets, the cytoplasmic tail of PEAR1 was found complexed to c-Src a

197 The cytoplasmic tail of POMGnT1 was found to be critical for

198 ng tyrosine phosphatase 2 phosphatase to the cytoplasmic tail of programmed death-1.

199 , replacing their cytoplasmic tails with the cytoplasmic tail of PSGL-1 significantly enhanced their

200 We further show that the cytoplasmic tail of rat ADAM17 contains a conserved seri

201 The cytoplasmic tail of Rbd2 appears to modulate PtdIns(4,5)

202 etic and biochemical studies showed that the cytoplasmic tail of Rbd2 binds directly to PtdIns(4,5)P2

203 GIV is recruited to the cytoplasmic tail of receptors upon stimulation, but the

204 onfirm that a linear sequence located in the cytoplasmic tail of Robo2 (residues 991-1070) interfaces

205 ith the first luminal loop of Glut4, and the cytoplasmic tail of sortilin binds to retromer.

206 on of a single lysine residue present in the cytoplasmic tail of the alpha chain, DMalpha.

207 ons, Lys4Gln and Ser15Tyr, in the N-terminal cytoplasmic tail of the alpha subunit of phosphotransfer

208 a the evolutionarily conserved lysine in the cytoplasmic tail of the beta chain in dendritic cells (D

209 osine kinase c-Src in platelets binds to the cytoplasmic tail of the beta3 integrin subunit via its S

210 XL[LI], or FXNPXY) or a CD8 protein with the cytoplasmic tail of the cation-independent mannose 6-pho

211 Here we reveal that the cytoplasmic tail of the GABABR2 subunit binds directly t

212 ract with both the small GTPase Rap1 and the cytoplasmic tail of the Heart of glass (HEG1) membrane a

213 s that engage two distinct epitopes from the cytoplasmic tail of the ligand Jagged1, one in the intra

214 teins separately, with each one fused to the cytoplasmic tail of the MV fusion protein.

215 the third intracellular loop of FPR2 nor the cytoplasmic tail of the receptor alone is responsible fo

216 e that the matrix (MA) domain of Gag and the cytoplasmic tail of the transmembrane glycoprotein gp41

217 Furthermore, the cytoplasmic tail of this Eph kinase regulates initial pl

218 a tyrosine-based motif at aa 888-891 in the cytoplasmic tail of TLR9 important for appropriate intra

219 Second, mutating Y731 in the cytoplasmic tail of VE-cadherin, known to selectively af

220 identified 4 amino acid substitutions in the cytoplasmic tail of viral envelope glycoprotein gp41 of

221 whereby Trp-76 anchors the C terminus of the cytoplasmic tail of Vpu to the plasma membrane, enabling

222 We found that features in the cytoplasmic tail of Vpu, specifically within the cytopla

223 ize interactions between 14-3-3-zeta and the cytoplasmic tails of alpha4, beta1, beta2 and beta3 inte

224 oplasmic domain-associated protein-1) to the cytoplasmic tails of beta1 integrins inhibits integrin a

225 rins, namely protein complexes formed on the cytoplasmic tails of bound integrins.

226 o found that polybasic motifs present in the cytoplasmic tails of CD43 and CD44 also promote their co

227 p120-catenin (p120) binds to the cytoplasmic tails of classical cadherins and inhibits ca

228 The cytoplasmic tails of human and simian immunodeficiency v

229 intracellular signals that act on the short cytoplasmic tails of integrin beta subunits.

230 ere it directly binds NPX(Y/F) motifs in the cytoplasmic tails of its target receptors to mediate the

231 Ms) are signaling domains located within the cytoplasmic tails of many transmembrane receptors and as

232 3 ligases that promote ubiquitination of the cytoplasmic tails of Notch ligands.

233 vide evidence for direct binding between the cytoplasmic tails of receptors and the WAVE complex, a r

234 ITAMs also have been identified in the cytoplasmic tails of some enveloped virus glycoproteins.

235 Signaling within the cell modifies the cytoplasmic tails of substrates, a step important in sta

236 lation of conserved tyrosine residues in the cytoplasmic tails of tetherin dimers.

237 by binding adaptor proteins to the flexible cytoplasmic tails of the alpha- and beta-integrin subuni

238 athway in which the Ycks prime a site on the cytoplasmic tails of the glucose sensors to promote bind

239 and Tyk2 phosphorylation, which bind to the cytoplasmic tails of the IL-4Ralpha/IL-13Ralpha1 complex

240 in which polybasic sequences present in the cytoplasmic tails of the membrane proteins and in Gag ar

241 ayers on the membrane association of the CD3 cytoplasmic tails of the T-cell receptors.

242 e (ALD) provides a critical link between the cytoplasmic tails of transmembrane adhesins and the acti

243 ors that bind to short, linear motifs in the cytoplasmic tails of transmembrane protein cargos and se

244 potential ubiquitin conjugation sites in the cytoplasmic tail or Lys residues in the ectodomain.

245 In contrast, the cytoplasmic tail or the naturally occurring C-terminal f

246 eolytic fragment of PC1 corresponding to the cytoplasmic tail, PC1-p30, is overexpressed in ADPKD.

247 We used L-selectin cytoplasmic tail peptide pulldown assays combined with h

248 Further analysis indicated that the F cytoplasmic tail plays a critical role in cell surface e

249 dition, TNS4 interaction with beta1-integrin cytoplasmic tail positively regulates beta1-integrin sta

250 he N terminus of the surface subunit and the cytoplasmic tail R peptide.

251 Mutations in the distal cytoplasmic tail region of M2, and in particular a tyros

252 reveal that independent regions of the CD30 cytoplasmic tail regulate the magnitude and type of NF-k

253 nomodulatory fusion proteins (IFPs) with the cytoplasmic tail replaced by the signaling domain of the

254 paB activation, indicating that the tetherin cytoplasmic tail resembles the hemi-immunoreceptor tyros

255 proximal and distal NPxY motifs of the beta1 cytoplasmic tail, respectively.

256 iciency virus (SIV) SIVmac239 envelope (Env) cytoplasmic tail resulted in a virus (DeltaGY) that exhi

257 ch expresses a chimeric hPIV1 F with the SeV cytoplasmic tail sequence grew similar to wt SeV or rSeV

258 re highly similar in structure, however, the cytoplasmic tail sequences of the envelope glycoproteins

259 Truncation of the NiV-F cytoplasmic tail (T5F) alone, combined with full-length

260 an Ig-like extracellular domain and a short cytoplasmic tail that associates with the adaptor DAP12.

261 MICA/B molecules and a dilysine motif in the cytoplasmic tail that confers retrieval from the Golgi a

262 scence response, we mapped the region in its cytoplasmic tail that controls signaling.

263 er, there are 5 tyrosine residues within the cytoplasmic tail that could potentially mediate TbetaRII

264 dileucine sorting signal encoded within the cytoplasmic tail that directs Notch to the limiting memb

265 ons to the F protein transmembrane domain or cytoplasmic tail that disrupted endocytic trafficking le

266 tion required arginine residues in the ICOSL cytoplasmic tail that recruited the adaptor protein RACK

267 vide evidence for a motif within the SorCS1c cytoplasmic tail that, when manipulated, results in pert

268 tivation, a conserved NPxY motif in integrin cytoplasmic tails that binds the FERM-domain-containing

269 brane-proximal segment in the integrin beta1 cytoplasmic tail, that Arg phosphorylates the membrane-p

270 mbrane by a mechanism requiring the receptor cytoplasmic tail, the intraflagellar transport complex-B

271 membrane distal NPXY motif in beta integrin cytoplasmic tails, thereby preventing lysosomal degradat

272 in 3 (GGA3) interacts directly with the TrkA cytoplasmic tail through an internal DXXLL motif and med

273 chimeric protein with its transmembrane and cytoplasmic tail (TMCT) domains substituted with those o

274 chimeric form in which its transmembrane and cytoplasmic tail (TMCT) domains were replaced with those

275 IT1 with ICAP1 and ICAP1 with integrin beta1 cytoplasmic tail to 2.54 and 3.0 A resolution (the resol

276 abilized MT1-MMP via direct tethering of its cytoplasmic tail to F-actin.

277 aments with latrunculin B or by mutating the cytoplasmic tail to impair binding to the cytoskeleton.

278 However, transfer of the human tetherin cytoplasmic tail to mouse tetherin restored restriction

279 et al. elucidate how the binding of the DSG1 cytoplasmic tail to the scaffolding protein Erbin decrea

280 g Ca(2+) concentrations cause the C-terminal cytoplasmic tail to transition from a mixture of extende

281 lar membrane-proximal regions, and the whole cytoplasmic tails, to the labeling of a membrane-permeab

282 ur results show how Pxn binding to the CD103 cytoplasmic tail triggers alphaEbeta7 integrin outside-i

283 mutation in the ezrin binding site, or with cytoplasmic tail-truncated CD44.

284 presentation by MHC-I molecules containing a cytoplasmic tail tyrosine signal (murine MHC-I molecules

285 Phosphorylation within CD300f cytoplasmic tail tyrosine-based motifs initiates signals

286 o the carboxy-terminal portion of the alpha5 cytoplasmic tail via a 91-residue region containing 13 f

287 K stimulation, SGEF is recruited to the Fn14 cytoplasmic tail via TRAF2.

288 h was an unexpected finding because its 7-aa cytoplasmic tail was assumed to be inert.

289 revealed, moreover, that the entire neurexin cytoplasmic tail was dispensable for heterologous synaps

290 gH chimera in which the gH transmembrane and cytoplasmic tail were replaced with that of human CD4 pr

291 ends on a short transferable sequence in the cytoplasmic tail, which contains the three crucial amino

292 C-I molecules containing a human MHC-I HLA-C cytoplasmic tail, which does not contain a tyrosine sign

293 st 12 amino acids of the longer (L-tetherin) cytoplasmic tail, which includes a tyrosine motif that a

294 ane proteins, the binding of adaptors to its cytoplasmic tail, which is 47 residues long and contains

295 s a gradual conformational change in the Smo cytoplasmic tail, which promotes the interaction between

296 provide inhibitory function, or a short (S) cytoplasmic tail with an unknown role.

297 ary structure of melanopsin indicates a long cytoplasmic tail with many potential phosphorylation sit

298 se inclusion or skipping generates different cytoplasmic tails with distinct functions.

299 However, replacing their cytoplasmic tails with the cytoplasmic tail of PSGL-1 si

300 Also, mutations of the beta3 cytoplasmic tail (Y747F and Y759F) that block beta3 tyro