ライフサイエンスコーパス: cytoskeletal

1 We examine whether binding of cytoskeletal adaptors to integrin cytoplasmic domains is

2 genesis and collecting duct cells had severe cytoskeletal, adhesion and polarity defects.

3 hanges in 37% of aging-dependent genes, with cytoskeletal and extracellular structure categories high

4 Cytokinesis requires the cooperation of many cytoskeletal and membrane regulators.

5 locking peptides attenuated TGF-beta-induced cytoskeletal and morphologic changes and apoptosis as di

6 ical signals from flowing blood to stimulate cytoskeletal and transcriptional responses that form a h

7 that even slight impairment of the podocyte cytoskeletal apparatus results in proteinuria and glomer

8 podocytes, including disruption of the actin cytoskeletal architecture and reduction of focal adhesio

9 Under these circumstances, the cytoskeletal architecture is dominated by contractile ac

10 Podocytes exhibit a unique cytoskeletal architecture that is fundamentally linked t

11 ying mechanisms responsible for dark-induced cytoskeletal arrangement remain largely unknown.

12 ctions, modulated by cell phenotype-specific cytoskeletal arrangements.

13 into the self-organization and mechanics of cytoskeletal assemblies.

14 crotubule filaments underlie the dynamics of cytoskeletal assemblies.

15 ase family regulate membrane trafficking and cytoskeletal assembly in many cells.

16 sm involving the shoulder subcomplex and the cytoskeletal-associated protein glycine-rich domain of N

17 that SW620Exos are significantly enriched in cytoskeletal-associated proteins including proteins acti

18 Cytoskeletal-associated proteins play an active role in

19 oup of serine/threonine kinases that feature cytoskeletal association.

20 rotein deposits is mediated by organelle and cytoskeletal attachment and by cell geometry.

21 OEA and PEA induced cytoskeletal changes and activated focal adhesion kinase

22 represent a trigger of both further podocyte cytoskeletal changes and inflammation, thereby playing a

23 We find that Nck-dependent cytoskeletal changes are mechanistically linked to enhan

24 r, in species with tiny spermatocytes, these cytoskeletal changes are restricted to one pole.

25 MeV infection was dependent on these dynamic cytoskeletal changes as well as fluid uptake through a m

26 emonstrate that imatinib attenuates multiple cytoskeletal changes associated with S1P-mediated endoth

27 age the Rho kinase Drok, implicating dynamic cytoskeletal changes in ARM, and this is supported by re

28 ally encoded component responsible for these cytoskeletal changes.

29 icitly accounts for detailed HIs between the cytoskeletal components and demonstrate the key conseque

30 us network that exhibits dynamic turnover of cytoskeletal components and internal force generation fr

31 e mode of T cell migration by inhibiting key cytoskeletal components and performing intravital two-ph

32 st array of enzymes, signaling adaptors, and cytoskeletal components.

33 These findings identify new cytoskeletal configurations and regulatory relationships

34 lect the emergence of different steady-state cytoskeletal conformations.

35 ts role in establishing normal smooth muscle cytoskeletal-contractile coupling.

36 Instead, alignment is driven by Rho-mediated cytoskeletal contractility and accelerated by propagatio

37 umor cell signals act in concert to modulate cytoskeletal contractility and adherens junctions disass

38 ence time at FAs, however, were dependent on cytoskeletal contractility on lower substrate stiffness

39 Finally, substrate stiffness and cytoskeletal contractility regulated whether vinculin an

40 ugh the use of pharmacological inhibitors of cytoskeletal contractility we find that endothelial cell

41 ilament sliding by myosin motors, as well as cytoskeletal cross-linking by myosins and nonmotor cross

42 .55; p = 8.0 x 10(-10)), encoding plectin, a cytoskeletal cross-linking protein that contributes to i

43 on of Rho-associated kinase (ROCK) prevented cytoskeletal defects, while inhibiting myosin light chai

44 a reduction of filamentous actin, elongated cytoskeletal dense bodies, and impaired intestinal smoot

45 ely reflect specialized tuning for localized cytoskeletal determinants, whereas dynein activity is le

46 uggested that NEK6 overexpression stimulated cytoskeletal, differentiation, and immune signaling path

47 Cytoskeletal disruption, which speeds PIP2 dispersion, a

48 rom DNA replication and protein synthesis to cytoskeletal dynamics and cofactor assimilation and serv

49 in many essential cellular events related to cytoskeletal dynamics and maintenance.

50 Collectively, cytoskeletal dynamics are achieved as a balance between

51 tant molecular mechanism whereby coordinated cytoskeletal dynamics contributes to cell adhesion regul

52 rmined how imbalances in regulation of actin cytoskeletal dynamics could result in pathological morph

53 urthermore, perturbing microtubule and actin cytoskeletal dynamics has an inverse relationship on the

54 roteins, but the role of this interaction in cytoskeletal dynamics has remained elusive.

55 flammatory response, antioxidant defense and cytoskeletal dynamics in HGFs.

56 ee systems but the role of tau in regulating cytoskeletal dynamics in living neurons is unknown.

57 1-Src regulates neuronal differentiation via cytoskeletal dynamics in the growth cone.

58 ting the apical cell membrane remodeling and cytoskeletal dynamics necessary for neural plate folding

59 We demonstrate that inhibiting cytoskeletal dynamics with pharmacological agents or by

60 a variety of regulatory processes, including cytoskeletal dynamics, cell-cycle progression, signal tr

61 e a new role of AMPK in the control of actin cytoskeletal dynamics, potentially allowing for long-ter

62 f these proteins includes manipulating actin cytoskeletal dynamics, regulating signal transduction pa

63 indirectly through their ability to control cytoskeletal dynamics.

64 ha2-chimaerin, a Rac-GAP GTPase that affects cytoskeletal dynamics.

65 recisely fulfill their specific functions in cytoskeletal dynamics.

66 drebrin as a potential coordinator of these cytoskeletal dynamics.

67 ion through integrins to be coordinated with cytoskeletal dynamics.

68 ndothelial cell adhesion, which is linked to cytoskeletal dynamics.

69 Here, we identify CLASP2 as a key cytoskeletal effector in the Reelin signaling pathway.

70 hoprotein (VASP) and Ena-VASP-like (EVL) are cytoskeletal effector proteins implicated in regulating

71 eristic is the apical complex-membranous and cytoskeletal elements at the apical end of the cell that

72 ute to the formation of an interface between cytoskeletal elements enriched in Protein 4.1B and betaI

73 Actin cytoskeletal elements, including myosin II motors and ac

74 n (LINC) complexes connecting the nucleus to cytoskeletal elements.

75 emarkably different from the other canonical cytoskeletal elements.

76 through corrective cellular organization of cytoskeletal elements.

77 by SF geometry and its connectivity to other cytoskeletal elements.

78 sin II (NMII) is a conserved force-producing cytoskeletal enzyme with important but poorly understood

79 ls treated with OEA and PEA were stained for cytoskeletal F-actin changes and lysed for immunoassay.

80 fic disruption of the TJ-associated ZO-1 and cytoskeletal-F-actin proteins, correlated with modulatio

81 adapted to parasitism and how characteristic cytoskeletal features are conserved.

82 omechanical network based on the microtubule cytoskeletal filament - itself a non-equilibrium chemica

83 The cytoskeletal Filamenting temperature-sensitive Z (FtsZ)

84 Cytoskeletal filaments and molecular motors facilitate t

85 Physics-based models of fibrous matrix, cytoskeletal force dipoles, and the lamin A gene circuit

86 only the combination of adaptor binding and cytoskeletal force provides ultrasensitive regulation.

87 a molecular model of integrin activation by cytoskeletal force.

88 We suggest that accumulation of cytoskeletal fragments around the aperture's rim during

89 rtap5-5 is a previously unknown regulator of cytoskeletal function in cancer cells that modulates mot

90 s demonstrate that R258C dominantly disrupts cytoskeletal functions attributed to SM alpha-actin in f

91 ors that had already evolved a wide range of cytoskeletal functions.

92 are consistent with deficiencies in multiple cytoskeletal functions.

93 ns regulating inflammatory, proteolytic, and cytoskeletal functions.

94 ers MAPK, AKT signaling pathways and ECM and cytoskeletal genes in lens cells that could contribute t

95 The cytoskeletal GTPase FtsZ assembles at midcell, recruits

96 show that TAOK2 directly phosphorylates the cytoskeletal GTPase Septin7, at an evolutionary conserve

97 ACTB encodes beta-actin, an abundant cytoskeletal housekeeping protein.

98 ysfunction, altered RNA metabolism, impaired cytoskeletal integrity, altered axonal transport dynamic

99 are essential for HSPC filopodia formation, cytoskeletal integrity, and homing via activation of CDC

100 at patient cells with both mutations exhibit cytoskeletal irregularities and severe defects in autoph

101 aterial both in the cell membrane and in the cytoskeletal layer beneath the membrane.

102 s, but at different rates and with different cytoskeletal linkage mechanisms.

103 clustering progrowth receptors and tethering cytoskeletal machinery necessary for neuronal sprouting.

104 derscoring the evolutionary importance of MT cytoskeletal manipulations for this virus family.

105 a platform for interpretation and design of cytoskeletal materials experiments, as well as for furth

106 Cytoskeletal mechanics regulates cell morphodynamics and

107 he evolutionary costs and benefits of tuning cytoskeletal mechanics remain an open question, one that

108 ytoskeleton dynamics, leading to a loss of a cytoskeletal mechanism in distal dendrites required for

109 Physiological significance and cytoskeletal mechanisms that maintain this shape are poo

110 cture, the "enucleosome," may mediate common cytoskeletal mechanisms underlying erythroblast enucleat

111 erconvert based on changes in cell adhesion, cytoskeletal mechanotransduction [5], and/or proteolysis

112 We hypothesize that this apparent cytoskeletal-membrane coupling could provide a mechanism

113 are hub genes - involved in RNA processing, cytoskeletal metabolism, intracellular trafficking, cell

114 differentiation and temporal interference of cytoskeletal microtubule-related motors.

115 eurodegenerative conditions with compromised cytoskeletal microtubules.

116 on using the immersed boundary method with a cytoskeletal model that incorporates structural details

117 ed boundary method, we compare this discrete cytoskeletal model to an existing continuum model and pr

118 I2 could reverse platelet spreading by actin cytoskeletal modulation, leading to reduced capability o

119 e RAB11a recruits its effector RAB11FIP3 and cytoskeletal motor Dynein, RAB27b mobilizes the effector

120 Cytoskeletal motor proteins are essential to the functio

121 describing their applications in studies on cytoskeletal motors and DNA replication.

122 Cytoskeletal motors drive many essential cellular proces

123 hlights recent progress in understanding how cytoskeletal motors orchestrate mRNA trafficking.

124 rom the force-generating mechanisms of other cytoskeletal motors.

125 and tubulin, are unable to polymerize either cytoskeletal network and fail to degranulate or release

126 in extracellular matrix remodeling activity, cytoskeletal network and interaction with microenvironme

127 ole of the physical interactions between the cytoskeletal network and the nucleus in cellular mechani

128 betaIII spectrin forms a detergent-resistant cytoskeletal network at these sites.

129 expected mechanism by which filaments of the cytoskeletal network compete for the moving organelles t

130 increased interest in the functions of this cytoskeletal network in differentiated cells, are result

131 ins unclear how the coordinated behaviour of cytoskeletal network may contribute to cell junctional d

132 As a consequence, these cytoskeletal networks failed to support cell adhesion at

133 However, the interconnectedness of cytoskeletal networks makes it difficult to dissect thei

134 the subcellular organization of contractile cytoskeletal networks plays a key role in force generati

135 ar envelope and transduce force from dynamic cytoskeletal networks to the nuclear lamina.

136 the plasma membrane (PM), where it regulates cytoskeletal organization and cell polarization.

137 gest an important role for tau in regulating cytoskeletal organization and dynamics during growth con

138 ence suggests close coupling between F-actin cytoskeletal organization and nuclear morphology however

139 ls and can be readily applied to investigate cytoskeletal organization and transport in other organis

140 lear positional dynamics is sensitive to the cytoskeletal organization by studying the effect of acti

141 ization and thereby contributes to proper MT cytoskeletal organization in interphase and mitosis.

142 h cytoskeletal quantification, we assess how cytoskeletal organization regulates nuclear state.

143 hanges in pathways related to proliferation, cytoskeletal organization, and apoptosis.

144 g sequence; and several proteins involved in cytoskeletal organization, cell communication, and regul

145 acellular matrix-mediated tissue remodeling, cytoskeletal organization, epithelial-to-mesenchymal tra

146 in-cross-linking protein known to coordinate cytoskeletal organization, interacts with the glucocorti

147 e metabolism, lipid droplet trafficking, and cytoskeletal organization.

148 mmunity in wheat via the modulation of actin cytoskeletal organization.

149 These results reveal a cytoskeletal pathway controlling autophagosomal remodeli

150 understanding of the signal transduction and cytoskeletal pathways that govern cell motility.

151 d EMT work through cell-matrix adhesions and cytoskeletal polarization, respectively.

152 Microtubules (MTs) are cytoskeletal polymers composed of repeating subunits of

153 native phospho-signaling, thus hampering the cytoskeletal processes required for macrophage phagocyto

154 membrane adhesome complexes that mediate the cytoskeletal processes required for tension generation.

155 e we apply CRISPR-Cas9 gene editing to tag a cytoskeletal protein (alpha-tubulin) and demonstrate a r

156 The cytoskeletal protein actin plays a critical role in main

157 enerative disease caused by mutations in the cytoskeletal protein beta-III-spectrin.

158 We show that a cytoskeletal protein betaIII spectrin plays a key role f

159 proteins that are highly represented: actin/cytoskeletal protein binding, RNA binding, RNA splicing/

160 multiscale process in which nanometer-scale cytoskeletal protein complexes, individual cells, and gr

161 y generated neurons, these cells express the cytoskeletal protein Doublecortin (DCX), yet they are ge

162 Talin, a cytoskeletal protein essential in mediating integrin act

163 sense mutations in the gene that encodes the cytoskeletal protein filamin B (FLNB), but a subset do n

164 Loss of function of KIND1, a cytoskeletal protein involved in beta1-integrin function

165 Previously we identified ankyrin G (AnkG), a cytoskeletal protein involved in vesicular transport, as

166 of Escherichia coli mutants in the essential cytoskeletal protein MreB for subtle changes in cell sha

167 own that through decreased activation of the cytoskeletal protein paxillin, growth factor-induced isc

168 The ubiquitously expressed cytoskeletal protein talin (Tln) is a component of muscl

169 hymal transition (EMT) and together with the cytoskeletal protein talin assemble into a signaling com

170 -generating enzyme PIPKIgamma couples with a cytoskeletal protein talin to control the acquisition of

171 nic disorder caused by the loss of the large cytoskeletal protein, dystrophin.

172 PPTT further enhanced the remodeling of cytoskeletal proteins and decreased migration.

173 s often caused by mutations in sarcomere and cytoskeletal proteins and is also associated with metabo

174 h, accompanying significant rearrangement of cytoskeletal proteins and plasma membranes.

175 Cytoskeletal proteins anillin and septin have been found

176 Cytoskeletal proteins ankyrin-G (AnkG) and betaIV-spectr

177 ally regulated protease substrates comprised cytoskeletal proteins as well as intermediate filaments.

178 d ZO-1/2/3 and between ZO-1/2/3 and numerous cytoskeletal proteins has been demonstrated in vitro, fl

179 derstanding of vRNA assembly and the role of cytoskeletal proteins in that process.

180 However, the role of host cytoskeletal proteins in the cytoplasmic assembly of IAV

181 invaginations and channels, and to visualize cytoskeletal proteins nearby.

182 Cytoskeletal proteins of the axon (betaIV spectrin, anky

183 insights into the distinct roles of the two cytoskeletal proteins on the recycling processes of SK2

184 Understanding how signaling pathways and cytoskeletal proteins pattern cell walls during this for

185 horylation cascade that includes erythrocyte cytoskeletal proteins resulting in changes in the viscoe

186 Septins are cytoskeletal proteins that assemble into nonpolar filame

187 ows pinpointing the contribution of distinct cytoskeletal proteins to nuclear mechanical state in phy

188 educes rapid redistribution of the important cytoskeletal proteins to the periphery and their associa

189 Force-sensitive cytoskeletal proteins, including myosin II motors and ac

190 nce of TNTs through its interaction with the cytoskeletal proteins.

191 spatial regulation of cell wall synthesis by cytoskeletal proteins.

192 By combining them with cytoskeletal quantification, we assess how cytoskeletal

193 es linked to unique migratory behaviours and cytoskeletal re-arrangements.

194 In vitro, anti-THSD7A antibodies caused cytoskeletal rearrangement and activation of focal adhes

195 vessel with human RBCs resulted in abnormal cytoskeletal rearrangement and release of intracellular

196 train pathogenic bacterial entry by limiting cytoskeletal rearrangement induced by bacterial effector

197 induce cellular fusion accompanied by rapid cytoskeletal rearrangement, even in non-muscle cells.

198 rentiation attenuated matrix mineralization, cytoskeletal rearrangement, mitochondrial dysfunction, a

199 for Plk4 in regulating Arp2/3-mediated actin cytoskeletal rearrangement.

200 conserved Src family kinase cascade to drive cytoskeletal rearrangements and target engulfment throug

201 Subsequently, GCK promoted cytoskeletal rearrangements by associating with actin.

202 on of a single SF within a monolayer induces cytoskeletal rearrangements in cells long distances away

203 al adhesion adaptor proteins that coordinate cytoskeletal rearrangements in response to integrin sign

204 al and intrinsic cues and converting them to cytoskeletal rearrangements that give rise to axons and

205 e polymerization, which is essential for the cytoskeletal rearrangements that occur during cellular d

206 pends on a balance between contractility and cytoskeletal rearrangements, adhesion, and mechanical ce

207 naptic neurotransmission, synaptic function, cytoskeletal rearrangements, energy metabolism, phosphol

208 onsistent with experimental observations for cytoskeletal reconfiguration through dysregulated RhoA o

209 HspB1 phosphorylation inhibits the protein's cytoskeletal recruitment in response to mechanical stimu

210 Such results support a paradigm of cytoskeletal regulation based on not only polymerization

211 We showed that these changes were linked to cytoskeletal regulation, and that expression of the smal

212 ariants, including microtubule transport and cytoskeletal regulation.

213 master regulator PHA-4/FoxA, followed by the cytoskeletal regulator and kinesin ZEN-4/MKLP1 and the p

214 ely spliced isoform of syntaphilin (SNPH), a cytoskeletal regulator of mitochondrial movements in neu

215 riants (SNVs) in the gene encoding the actin cytoskeletal regulator tropomyosin 4 (TPM4) exert an eff

216 Inhibition of the cytoskeletal regulatory Abl family kinases in the oPFC r

217 To test this, we inhibited the cytoskeletal regulatory factor Rho kinase.

218 es in non-neuronal cells indicate that actin cytoskeletal regulatory pathways in nuclei have a direct

219 To determine whether cytoskeletal regulatory systems in the oPFC influenced d

220 -life cocaine use may benefit from targeting cytoskeletal regulatory systems.

221 tified integrin-linked kinase and associated cytoskeletal remodeling and adhesion to be among HIF-dep

222 cated that Sox11 activates genes involved in cytoskeletal remodeling and axon growth.

223 st immune system, including interfering with cytoskeletal remodeling as a way to block macrophage pha

224 nous (Dia)-related formins (DRFs) coordinate cytoskeletal remodeling by controlling actin nucleation

225 major controller of actin dynamics and actin cytoskeletal remodeling in cells.

226 Rac1 induces TRPC5 ion channel activity and cytoskeletal remodeling in podocytes.

227 exin proteins may link membrane resealing to cytoskeletal remodeling processes in single cell wound r

228 on adhesive micropatterns to investigate the cytoskeletal remodeling supporting it.

229 ially protected podocytes from SMPDL3b loss, cytoskeletal remodeling, and caspase 3 cleavage.

230 llular responses, including nuclear shaping, cytoskeletal remodeling, and the mechanotransduction of

231 onstrate that radiation injury induces early cytoskeletal remodeling, down-regulation of SMPDL3b, and

232 AIM1 in prostate epithelial cells increases cytoskeletal remodeling, intracellular traction forces,

233 Mechanosensitive proteins are key players in cytoskeletal remodeling, muscle contraction, cell migrat

234 on by bridging tyrosine phosphorylation with cytoskeletal remodeling, the role of Nck in tumorigenesi

235 kidney filter dynamics by balancing podocyte cytoskeletal remodeling.

236 ocytes were protected from radiation-induced cytoskeletal remodeling.

237 veal that they not only drive but also brake cytoskeletal remodeling.

238 of the small GTPase RhoA to drive actomyosin cytoskeletal remodeling.

239 e and substantiate its physiological role in cytoskeletal remodeling.

240 d of dynamic membrane resealing and cortical cytoskeletal remodeling.

241 also in genes involved in axon guidance and cytoskeletal remodeling.

242 s a major role in Ca(2+) /cation signalling, cytoskeletal remodelling and barrier function in retinal

243 The intracellular fragment of ODZ1 promotes cytoskeletal remodelling of GBM cells and invasion of th

244 we investigated the effects of cAMP-induced cytoskeletal remodelling on the serum response factor (S

245 k transcriptional programs with adhesive and cytoskeletal remodelling.

246 enetic control of cell adhesion, chemotaxis, cytoskeletal reorganisations, cell proliferation, cell d

247 mechanism by which Galpha13 signals to actin cytoskeletal reorganization is not completely understood

248 r and receptor tyrosine kinase-induced actin cytoskeletal reorganization such as dynamic dorsal ruffl

249 t-evoked effects on barrier permeability and cytoskeletal reorganization were antagonized by the sele

250 tivating functions such as degranulation and cytoskeletal reorganization, but also in less well-under

251 G-proteins, Galpha13, is critical for actin cytoskeletal reorganization, cell migration, cell prolif

252 ling, which is involved in cell motility and cytoskeletal reorganization, resulted in reduced RVFV re

253 bition of p38 MAPK abrogates stretch-induced cytoskeletal reorganization.

254 ing pathway by which Galpha13 controls actin cytoskeletal reorganization.

255 ctin interaction could have broad utility in cytoskeletal research and further our understanding of t

256 ases), is critical for this actin and myosin cytoskeletal response in which they form distinct dynami

257 A high sensitivity of the cytoskeletal rheology and structure to minor changes in

258 The cytoskeletal scaffolding protein ankyrin G (AnkG) has be

259 Keratin 16 (K16) is a cytoskeletal scaffolding protein highly expressed at pre

260 sis in cancer cells by knocking down ANLN, a cytoskeletal scaffolding protein that regulates cytokine

261 the molecular components of the node is the cytoskeletal scaffolding protein, ankyrin G (AnkG), whic

262 ion and modulates Rho-GTPase-dependent actin cytoskeletal signaling in fetal lungs.

263 up-regulation of Rho-GTPase-dependent actin cytoskeletal signaling that can lead to loss of tissue i

264 TRPV4 channels regulate calcium homeostasis, cytoskeletal signalling and the organization of adherens

265 ays left-handed and is not due to underlying cytoskeletal skewing, as is the case in other known, phe

266 rsity act as a "tubulin code" that regulates cytoskeletal stability and the activity of MT-associated

267 esponse to hyperglycemia perturbs neutrophil cytoskeletal stability leading to MP production and IL-1

268 are coregulated with neurotoxicity and actin cytoskeletal stabilization in brains of flies expressing

269 required to form tunnels due to the reduced cytoskeletal stiffness and thickness of these cells, sim

270 s rooted in protein stabilization induced by cytoskeletal stress.

271 5 expression has a major impact on the actin cytoskeletal structure and cell adhesion in the absence

272 GTPase signaling and are essential for actin cytoskeletal structure and contractility.

273 ion, the MYH9 E1841K variant alters podocyte cytoskeletal structure and renders podocytes more suscep

274 eling is spatiotemporally coordinated with a cytoskeletal structure pertaining to a kingdom of life,

275 estrated series of spatiotemporal changes in cytoskeletal structure to divide their genetic material.

276 mporal effects of Abl kinases on endothelial cytoskeletal structure using AFM, SEM, and immunofluores

277 ains that differ in membrane composition and cytoskeletal structure, and sets the platform on which m

278 fiber stiffness/density resulted in altered cytoskeletal structure, increased tight junction (TJ) fo

279 ork to accurately segment and quantify actin cytoskeletal structures and Golgi transport.

280 Cytoskeletal structures characterized by actin filaments

281 Although the cytoskeletal structures have been analyzed extensively,

282 shape, cytoplasm, nucleus, lipid bodies and cytoskeletal structures in 3D with unprecedented biomole

283 As P10 polymerizes to form organized cytoskeletal structures that colocalize with host cell m

284 ssociated with the flagellum via a series of cytoskeletal structures that include the hook complex (H

285 te, they can enable complexes, organelles or cytoskeletal structures to assemble around existing cell

286 olution microscopy, we investigate how these cytoskeletal systems interface during migration.

287 dinates actin and MT networks, the two major cytoskeletal systems involved in membrane trafficking an

288 Because a force balance among different cytoskeletal systems is important to maintain normal tis

289 chanics by balancing and tuning forces among cytoskeletal systems.

290 the AKAP79/150 N-terminal polybasic membrane-cytoskeletal targeting domain were phosphorylated more e

291 ed with the activation of Rac GTPase and its cytoskeletal targets.

292 titutively activated, resulting in increased cytoskeletal tension and impaired cell-cell adhesion.

293 quirement for degradation was independent of cytoskeletal tension generation and presentation of engi

294 tified matrix remodelling, in the absence of cytoskeletal tension generation, as a previously unknown

295 5 binding to GPA leads to an increase in the cytoskeletal tension of the red cell and a reduction in

296 onsistent across different ECM stiffness and cytoskeletal tension states.

297 regulation of epithelial barrier formation, cytoskeletal tension, and cell adhesion, underscoring th

298 be supported by internal forces produced by cytoskeletal tension.

299 at vesicles at the plasmalemma are guided by cytoskeletal tracks to specific sites on the membrane th

300 importance of modulations of cell signaling, cytoskeletal transport, and microtubule dynamics for axo