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   1  T-cell expression of programmed death-1 and cytotoxic T lymphocyte-associated antigen-4.            
     2 d-induced tumor necrosis factor receptor and cytotoxic T-lymphocyte-associated antigen-4.            
     3  markers, including FOXP3, CD25, Helios, and cytotoxic T lymphocyte-associated antigen 4; and impaire
     4 he NKG2D pathway in the clinical activity of cytotoxic T lymphocyte-associated antigen 4 antibody blo
     5 via ex vivo CD40 ligand (CD40L)/CD40 or CD28/cytotoxic T lymphocyte-associated antigen 4/B7 blockade 
  
  
     8 tic virus) in combination with ipilimumab (a cytotoxic T-lymphocyte-associated antigen 4 checkpoint i
     9  The administration of antibodies that block cytotoxic T lymphocyte associated antigen-4 (CTLA-4) to 
    10 ckpoint blockade with antibodies that target cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and
    11 ceptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and
  
  
  
    15 ct with the costimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) exp
  
  
    18   Blockade of inhibitory signals mediated by cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) has
    19 ess activation of T cells in the presence of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) imm
  
  
  
  
  
  
  
  
    28 d with a CTLA-4Ig fusion protein and an anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) mon
    29 in the expression of the inhibitory molecule cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) on 
    30 ocking inhibitory immune checkpoints such as cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) or 
    31 atment with monoclonal antibody specific for cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), an
    32 ice and display characteristic expression of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), gl
    33  tumor cell vaccines or antibody blockade of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).   
    34 two related cell-surface receptors, CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).   
    35  through CD28 and inhibitory signals through cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).   
  
    37 ing factor (GM-CSF) and antibody blockade of cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) tri
    38 markers glucocorticoid-induced TNF receptor, cytotoxic T lymphocyte-associated antigen-4 (CTLA-4), an
  
  
    41 ndividuals, immunosuppression is mediated by cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and
    42 tance: Checkpoint blockade therapy targeting cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and
  
    44 hibits an immunologic checkpoint on T cells, cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4).   
    45  anti-programmed cell death-1 (PD-1) or anti-cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) ant
  
    47 pilimumab, a monoclonal antibody that blocks cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) sig
  
    49 ether vaccination administered together with cytotoxic-T-lymphocyte-associated antigen 4 (CTLA-4) blo
  
    51 NE study, we investigated the effects of the cytotoxic-T-lymphocyte-associated antigen 4 (CTLA-4) mon
    52 ly of molecules on APCs with CD28 and CD152 (cytotoxic T lymphocyte-associated antigen 4 [CTLA-4]) re
    53 r T cell-associated ligands, CD28 and CD152 (cytotoxic T lymphocyte-associated antigen-4 [CTLA-4]), p
    54 D-1] checkpoint inhibitor) and ipilimumab (a cytotoxic T-lymphocyte-associated antigen 4 [CTLA-4] che
    55 geted (BRAF or MEK) or an immune checkpoint (cytotoxic T-lymphocyte-associated antigen 4 [CTLA-4] or 
    56 th melanoma, ipilimumab (an antibody against cytotoxic T-lymphocyte-associated antigen 4 [CTLA-4]) pr
  
    58 5RB, CD62L, CD103) or intracellular markers (cytotoxic T-lymphocyte-associated antigen-4, CTLA-4, and
    59 A to an aptamer (apt) that selectively binds cytotoxic T lymphocyte-associated antigen 4 (CTLA4(apt))
    60 include monoclonal antibodies that block the cytotoxic T lymphocyte-associated antigen 4 (CTLA4) and 
  
  
    63 ponsive beige-like anchor protein (LRBA) and cytotoxic T lymphocyte-associated antigen 4 (CTLA4) defi
  
  
    66 t that blockade of the coinhibitory molecule cytotoxic T lymphocyte-associated antigen 4 (CTLA4) on l
    67 nuclear factor kappaB-inducing kinase (NIK), cytotoxic T lymphocyte-associated antigen 4 (CTLA4), B-c
    68 ration of regulatory T cells (T(reg) cells), cytotoxic T lymphocyte-associated antigen 4 (CTLA4), int
  
    70 remelimumab (CP-675,206), a fully human anti-cytotoxic T-lymphocyte-associated antigen 4 (CTLA4) mono
    71 unctions by TR cells was TGFbeta, IL-10, and cytotoxic T lymphocyte-associated antigen 4 dependent.  
  
    73 as ligand, Fas, perforin, interleukin-2, and cytotoxic T-lymphocyte-associated antigen-4 exist and in
    74 w costimulatory blockade agents, such as the cytotoxic T lymphocyte-associated antigen 4-Ig molecule 
  
    76 tein-1, and IL-12/IL-23 and proliferation of cytotoxic T-lymphocyte-associated antigen 4 immunoglobul
    77                                   Abatacept (cytotoxic T-lymphocyte-associated antigen 4-immunoglobul
    78 h in vitro blockade of programmed death-1 or cytotoxic T lymphocyte-associated antigen-4 increased T-
    79 patients who respond to antibody-blockade of cytotoxic T lymphocyte-associated antigen 4 or vaccinati
    80 dulating agents, such as antibodies blocking cytotoxic T lymphocyte-associated antigen-4 or programme
    81 ath ligand (PD-L)1 pathway, not the distinct cytotoxic T lymphocyte-associated antigen 4 pathway.    
    82 eptors (inducible costimulator, OX40, 4-1BB, cytotoxic T lymphocyte associated antigen-4, programmed 
    83 variety of coinhibitory molecules, including cytotoxic T lymphocyte-associated antigen-4, programmed 
    84 this phase 3 study, ipilimumab--which blocks cytotoxic T-lymphocyte-associated antigen 4 to potentiat
    85 atory markers FOXP3, programmed death-1, and cytotoxic T lymphocyte-associated antigen-4 was examined
    86  further improved when coinhibitory receptor cytotoxic T-lymphocyte-associated antigen 4 was blocked 
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