ライフサイエンスコーパス: cytotoxic activity

1 th TNF-alpha and IFN-gamma and showed potent cytotoxic activity.

2 in the presence of HLA-A2, without eliciting cytotoxic activity.

3 NK) cells are innate lymphocytes with potent cytotoxic activity.

4 control CD19(+) B cells and increased their cytotoxic activity.

5 ) T cells after Ag presentation and impaired cytotoxic activity.

6 LM for DNA cleavage, cancer cell uptake, and cytotoxic activity.

7 pacity to driving T cell differentiation and cytotoxic activity.

8 he ability to produce effector cytokines and cytotoxic activity.

9 t fully with differences in the intensity of cytotoxic activity.

10 ted tumor growth by inhibiting CD8(+) T cell cytotoxic activity.

11 ortant role of mitochondria in mediating the cytotoxic activity.

12 or is an ATP-gated ion channel known for its cytotoxic activity.

13 esponses, but may also acquire TLR-triggered cytotoxic activity.

14 /CA/07/2009) peptides and showed evidence of cytotoxic activity.

15 ed peptide-specific IFN-gamma production and cytotoxic activity.

16 and MyD88(-/-) mice showed markedly impaired cytotoxic activity.

17 manner that was correlated tightly with its cytotoxic activity.

18 f POPC/POPS liposomes for peptides with high cytotoxic activity.

19 sed on tumor cells that can activate NK cell cytotoxic activity.

20 that affect their biochemical behaviour and cytotoxic activity.

21 utation restored both hemolytic activity and cytotoxic activity.

22 ATM-p53 apoptosis pathway that underlies its cytotoxic activity.

23 gondii cysts through their perforin-mediated cytotoxic activity.

24 e natural product that possesses significant cytotoxic activity.

25 e impairment of their antigen specificity or cytotoxic activity.

26 liminate pathogens through perforin-mediated cytotoxic activity.

27 rferon (IFN-gamma)-secreting T cells display cytotoxic activity.

28 results in a significant reduction of their cytotoxic activity.

29 l antibody rituximab further increased their cytotoxic activity.

30 duced gamma interferon and displayed in vivo cytotoxic activity.

31 ated but still in an immature state with low cytotoxic activity.

32 4-1BB(-) cells were inert and unable to gain cytotoxic activity.

33 macological GSK3 inactivation enhances their cytotoxic activity.

34 ients (AML-NK) show a dramatic impairment in cytotoxic activity.

35 and they mediate influenza A virus-specific cytotoxic activity.

36 ven by chronic TCR stimulation while sparing cytotoxic activity.

37 rain JGS1076 CPB variant that possessed more cytotoxic activity.

38 Ls and NK cells diminishes degranulation and cytotoxic activity.

39 ivation and DNMT1 expression correlated with cytotoxic activity.

40 says the compounds displayed anti-fungal and cytotoxic activity.

41 essing cancer cells, displaying MET-specific cytotoxic activity.

42 iterpenes with significant antimicrobial and cytotoxic activities.

43 ial source of compounds with antioxidant and cytotoxic activities.

44 Two nucleoside derivatives with promising cytotoxic activities (11 and 12) were further analyzed o

45 Thus, cisplatin has two potential cytotoxic activities: (a) the generation of ICLs and (b)

46 gnificant enhancement in cellular uptake and cytotoxic activity after 1h of heating at 42 degrees C w

47 etides known for their unique structures and cytotoxic activities against human cancer cell lines.

48 s as well as effective antiproliferative and cytotoxic activities against human tumor cells.

49 NT-7-16 exhibits antiproliferative and cytotoxic activities against multiple cancer cell lines,

50 ed that human eosinophils and T cells shared cytotoxic activities against tumor cells that involved t

51 and largazole thiol were further assayed for cytotoxic activity against a panel of chemoresistant mel

52 nanomolar concentration and showed in vitro cytotoxic activity against a panel of human tumor cell l

53 erivative, 3 [Ga(ACtpfc)], demonstrated high cytotoxic activity against all NCI60 cell lines derived

54 Additionally, Vah1 and RtxA each have cytotoxic activity against Atlantic salmon kidney (ASK)

55 TILN NK cells display robust cytotoxic activity against autologous melanoma cells.

56 NKp46+ CD3+ cells exhibit cytotoxic activity against autologous Theileria parva-in

57 xic against malignant B-cell lines, has high cytotoxic activity against cells directly isolated from

58 ers, including CD56+ and perforin, and exert cytotoxic activity against different human tumor target

59 increased binding affinity to and increased cytotoxic activity against Fas(+) target cells.

60 5, 8, 9, 11, and 13 were evaluated for their cytotoxic activity against four cancer cell lines (SK-ME

61 inhibitor G5 were synthesized and tested for cytotoxic activity against glioblastoma cells.

62 Two R. sempervirens extracts exerted cytotoxic activity against HeLa and HT-29 cell lines, bu

63 excellent pharmacokinetics, potent in vitro cytotoxic activity against Her2(+) cancer cells, and com

64 Importantly, these CTLs recognized and had cytotoxic activity against HLA-A*02(+)/PRAME(+) tumor ce

65 thalene B-ring (8 and 14) showed significant cytotoxic activity against KB and other cancer cell line

66 diol and clauslactone E showed a significant cytotoxic activity against Leishmania major with IC50 va

67 IL) is a death ligand cytokine known for its cytotoxic activity against malignantly transformed cells

68 prepared 2H-chromenes demonstrated profound cytotoxic activity against MCF-7 cell line.

69 eration arrest and apoptosis without causing cytotoxic activity against normal human CD34(+) progenit

70 show that human neutrophils display a higher cytotoxic activity against poorly metastatic cells compa

71 Seventeen new macrocycles were evaluated for cytotoxic activity against RPMI 8402, KB-3, and KB-3 cel

72 nolactone-2',3'-diol possessed the strongest cytotoxic activity against SBC3, A549, K562, and K562/AD

73 These nanovesicles display cytotoxic activity against several tumor cell lines and

74 p70 to form a stable Tag7-Hsp70 complex with cytotoxic activity against some tumor cell lines.

75 Natural killer (NK) cells display cytotoxic activity against susceptible target cells and

76 activated macrophages exhibited NK cell-like cytotoxic activity against target cells in a perforin/gr

77 or allogeneic sources, thereby promoting NK cytotoxic activity against target cells that would not b

78 r endothelial cells in vitro, they only show cytotoxic activity against the tumor endothelial cells.

79 ator of the cytotoxic effect, as the reduced cytotoxic activity against the yeast cells detected in p

80 A-D expression, cancerous pDCs did not exert cytotoxic activity against tumor cells but instead promo

81 Natural killer (NK) cells not only exert cytotoxic activity against tumor cells or infected cells

82 idylinositol (D-3-deoxy-PI) derivatives have cytotoxic activity against various human cancer cell lin

83 , that exhibits potent antiproliferative and cytotoxic activity along with client protein degradation

84 Unlike in WT, in vivo cytotoxic activity analysis of alloreactive Tmem recall

85 Tc17/IFN-gamma) subsets that exhibit strong cytotoxic activities and are associated with pathogenesi

86 The antibody Fc region regulates antibody cytotoxic activities and serum half-life.

87 s model drugs, as these agents have a potent cytotoxic activity and are easy to synthesize.

88 ng to proteolysis products also promoted the cytotoxic activity and binding of enterotoxin and beta t

89 f TGF-beta1 was sufficient to augment T cell cytotoxic activity and blocked tumor growth and metastas

90 in a series of cell-culture assays to assess cytotoxic activity and cell binding.

91 , we investigated the mechanisms controlling cytotoxic activity and cytokine production in response t

92 gnaling pathways responsible for controlling cytotoxic activity and cytokine production.

93 ns offer unique advantages such as increased cytotoxic activity and diminished antibody recognition,

94 in designed to have low-immunogenicity, high-cytotoxic activity and fewer side effects.

95 tion generated effector CD8 T cells with low cytotoxic activity and high IL-2 production.

96 e, which correlated with increased pulmonary cytotoxic activity and increased pulmonary expression of

97 C. jejuni OMVs possess cytotoxic activity and induce a host immune response fro

98 Cytotoxic activity and interferon-gamma (IFN-gamma) secr

99 re stimulated effector CD8 T cells with high cytotoxic activity and low IL-2 production, brief (<24 h

100 from mice pretreated with alphaGalCer retain cytotoxic activity and maintain the ability to respond t

101 including stimulation of natural killer cell cytotoxic activity and repression of Hedgehog-dependent

102 nvestigate the correlation between immediate cytotoxic activity and short-term cytokine secretion.

103 low-affinity alphabeta-TCR maintained potent cytotoxic activity and specificity, the high-affinity TC

104 dichroism studies, a correlation between the cytotoxic activity and the alpha-helical propensity was

105 antigen presentation, chemokine expression, cytotoxic activity, and adaptive immune resistance, and

106 Y-ESO-1-specific CD8(+) T cells by enhancing cytotoxic activity, and improving viability and prolifer

107 bound CEACAM6 with high affinity, exhibited cytotoxic activity, and induced dose-dependent poly(ADP-

108 ted protein kinase (MAPK) signaling, in vivo cytotoxic activity, and intratumoral cytokine secretion

109 ts with P. aeruginosa pneumonia demonstrated cytotoxic activity, and lavage fluid contained amyloid m

110 dness, tested their culture supernatants for cytotoxic activity, and searched for secreted toxins.

111 The new compounds were evaluated for their cytotoxic activity, and this allowed the identification

112 Surprisingly, CD4(+) T cells developed cytotoxic activity, and tumor rejection was dependent on

113 -specific cells that are granzyme B(+), have cytotoxic activity, and/ or produce interferon gamma (IF

114 Their cytotoxic activity appears to involve redox mechanisms.

115 free drug in functional cellular assays for cytotoxic activity approaching or matching the activity

116 publicly available library of compounds with cytotoxic activity ( approximately 21,000 compounds), in

117 through which pDCs acquire and elicit their cytotoxic activity are still not clear.

118 ty to secrete IFN-gamma but maintaining some cytotoxic activity as granzyme B and FasL are overexpres

119 sponge Ecionemia acervus that shows in vitro cytotoxic activities at submicromolar concentrations.

120 hereas the presence of an Fc domain enhanced cytotoxic activity, but triggered antigen-independent T-

121 However, most reports observed a lack of cytotoxic activity by Tc17 cells.

122 invasion by gentamicin survival assays, and cytotoxic activity by Trypan blue exclusion assays.

123 pyrimidine nucleosides had low-to-negligible cytotoxic activity (CC50 > 1000-1209 microM).

124 d 15-fold greater REV-ERBbeta inhibitory and cytotoxic activities compared to 1.

125 idation led to a decrease of antioxidant and cytotoxic activities compared to initial substrates.

126 echanistic studies reveal that the increased cytotoxic activity correlates with an increase in AML-NK

127 Cytotoxic activity could be reconstituted in both mutant

128 f antigen-specific CD8 T cells in vivo exert cytotoxic activity during a functional CD8 T-cell respon

129 trating neutrophil recruitment and eliciting cytotoxic activity during an inflammatory response.

130 ion, as low affinity-primed T cells acquired cytotoxic activity earlier than high affinity-primed one

131 Notably, the compounds showed no cytotoxic activity, encouraging their further evaluation

132 ese results suggest that the degradative and cytotoxic activities exhibited by StmPr1 may contribute

133 Cytotoxic activity follows Hsc70-mediated escape of RTA

134 nsic antibody activities and showed enhanced cytotoxic activity from targeted payload delivery.

135 activities, mutagenic/genotoxic activities, cytotoxic activities, further activities like neurotoxic

136 into the nanoparticles to confer synergistic cytotoxic activity, further highlighting the potential a

137 olin-6-one (16a) exhibited the best in vitro cytotoxic activity (GI50 10-66.9 nM) against the NCI 60

138 infected mice correlated with higher NK cell cytotoxic activity, higher expression of cytotoxic molec

139 lubility and stability, demonstrated extreme cytotoxic activity (IC50 < 5.0 mug/mL) to cancer cells c

140 The levels of intracellular IFN-gamma, cytotoxic activity, IFN-gamma and granzyme B secretion,

141 They display cytotoxic activities in the micromolar range on many can

142 s I51/A114 and at V56/F118 lacked detectable cytotoxic activity in a MDCK cell assay.

143 Arsenic sulfide (AS) has excellent cytotoxic activity in acute promyelocytic leukemia (APL)

144 from avocado fruit, as a novel compound with cytotoxic activity in AML.

145 chanism paralleling that responsible for the cytotoxic activity in cancer cells.

146 t, and HSP70 inhibitors exert tumor-specific cytotoxic activity in cancer.

147 levels correlated with in vivo allospecific cytotoxic activity in CD8 knockout hepatocyte rejector m

148 ANT61, which reveal the basis for its unique cytotoxic activity in colon carcinoma cells.

149 fferent dynamics of numerical alteration and cytotoxic activity in HIV-infected patients.

150 gly, this behavior correlates with efficient cytotoxic activity in human osteosarcoma and colon carci

151 ology, highlighting the important role of NK cytotoxic activity in immune homeostasis.

152 oles was synthesized and evaluated for their cytotoxic activity in in vitro tumor models.

153 whether mucosal B cells express GrB and have cytotoxic activity in inflammatory bowel disease (IBD).

154 The cytotoxic activity in nonirradiated cells of novel phtha

155 These species have little or no cytotoxic activity in several bioassays.

156 iscovery of sudemycin D6, which shows potent cytotoxic activity in the melanoma line SK-MEL-2 (IC50 =

157 units permits access to analogues possessing cytotoxic activity in the nanomolar range.

158 ificant increase in IFN-gamma production and cytotoxic activity in TILs that acquired H-RasG12V compa

159 active properties (antioxidant potential and cytotoxic activity in tumor cell lines).

160 onjugates displayed potent antigen-selective cytotoxic activity in vitro and antitumor activity in vi

161 ecognizes peptide in the context of MHC, has cytotoxic activity in vitro and prevented growth of tumo

162 cient NK cells display significantly less NK cytotoxic activity in vitro than WT NK cells.

163 e producing either one or both toxins showed cytotoxic activity in vitro that translated directly int

164 responders and nonresponders have equivalent cytotoxic activity in vitro.

165 expressed cell surface CD107a, and exhibited cytotoxic activity in vivo.

166 s in human laryngeal carcinoma cells causing cytotoxic activity, in a dose dependent manner.

167 thereby only allowing self S-RNase to exert cytotoxic activity inside a pollen tube.

168 d temperature sensitive, suggesting that its cytotoxic activity is due to secreted proteins, some of

169 r, on the contrary to the enhancement of its cytotoxic activity, is a reaction of physiological impor

170 responding approximate 3-5-fold reduction in cytotoxic activity [L1210 IC(50) for (+)-iso-duocarmycin

171 The differences in the cytotoxic activities of 1 and 2 were suggested to be due

172 relative antibacterial, antiplasmodial, and cytotoxic activities of a series of proline-free and pro

173 rate a concept in which antibacterial versus cytotoxic activities of cationic small molecules are tun

174 Antioxidant and cytotoxic activities of digestates were also measured us

175 iate the immunomodulatory, inflammatory, and cytotoxic activities of human IgG antibodies and Fc engi

176 believed to be the molecular target for the cytotoxic activities of platinum (Pt) anticancer drugs.

177 A comparison between the cytotoxic activities of Pt(IV)-encapsulated PLGA-b-PEG N

178 tment with ibrutinib significantly augmented cytotoxic activities of standard AML chemotherapy cytara

179 The cytotoxic activities of the novel polyaminocarboxylates

180 The cytotoxic activities of these compounds and their intera

181 uster, are responsible for the hemolytic and cytotoxic activities of V. anguillarum in fish.

182 ell lines is examined, observing a promising cytotoxic activity of (+)-T7 against breast carcinoma ce

183 The cytotoxic activity of 10 analogs of the idealized amphip

184 oline derivatives (8-HQs) and focuses on the cytotoxic activity of 5-Cl-7-I-8-HQ (clioquinol, CQ) cop

185 Whereas increased Ag-specific cytotoxic activity of a CD8(+) T cell line manifested in

186 We studied the cytotoxic activity of a vesicular stomatitis/measles hyb

187 ort that SAHA inhibits the proliferative and cytotoxic activity of anti-CD3-activated T cells.

188 Finally, blockade of Rpn11 increases the cytotoxic activity of anti-MM agents lenalidomide, pomal

189 lity of this protocol was illustrated on the cytotoxic activity of azadiradione derivatives against s

190 Interestingly, I-CBP112 increased the cytotoxic activity of BET bromodomain inhibitor JQ1 as w

191 Time-lapsed microscopy revealed potent cytotoxic activity of bscEphA2xCD3-activated T cells aga

192 of human CMV (HCMV) infection depends on the cytotoxic activity of CD8(+) CTLs.

193 tralizing antibody production by B cells and cytotoxic activity of CD8(+) T cells are well-accepted c

194 mice, particularly regarding frequencies and cytotoxic activity of CD8(+) T cells.

195 e trastuzumab emtansine (T-DM1) combines the cytotoxic activity of DM1 with the human epidermal growt

196 Strong cytotoxic activity of DSA was associated with a higher r

197 However, cytotoxic activity of DSA was not correlated to antibody

198 tly, bispecific antibodies that redirect the cytotoxic activity of effector T cells by binding to CD3

199 PI(4,5)P2 levels was less susceptible to the cytotoxic activity of ExoU.

200 n cancer cells and provide evidence that the cytotoxic activity of HDACi in cancer is not only depend

201 p28 enhanced the cytotoxic activity of lower concentrations (IC20-50) of

202 The impairment of cytotoxic activity of lymphocytes disturbs immune survei

203 gest that acylation is not necessary for the cytotoxic activity of M. haemolytica Lkt but that it enh

204 n light of the reported selective and potent cytotoxic activity of maoecrystal V, the cytotoxic prope

205 Pretreatment with decitabine decreased the cytotoxic activity of MEK inhibitors in KRAS-mutant ovar

206 ith human blood and also in mice, mimics the cytotoxic activity of natural killer cells and increases

207 IL-27 also enhances cytotoxic activity of NK cells both in vitro and in vivo

208 thermore, regulation by HNRNPR modulates the cytotoxic activity of NK cells.

209 At 10 nM, 33 and 44 stimulated the cytotoxic activity of NK cells.

210 The cytotoxic activity of our PRAME-specific CTLs was direct

211 enhanced proliferation in vivo and enhanced cytotoxic activity of PD-1-deficient T lymphocytes again

212 CD16 expression and rituximab-dependent cell cytotoxic activity of peripheral NK cells in HT recipien

213 NC-ADCC was not affected by C5 cleavage, the cytotoxic activity of PMN in the presence of serum stron

214 ial correlated with Fasl expression, and the cytotoxic activity of postinfection Tc17 cells was parti

215 nt with inhibitor, 7rh, greatly enhanced the cytotoxic activity of RG7787 in several cancer cell line

216 the possible use of this protein against the cytotoxic activity of ribosome-inactivating proteins.

217 -acetylcholinesterase, anti-inflammatory and cytotoxic activity of rose hips and the preserves (puree

218 content, antioxidant, anti-inflammatory and cytotoxic activity of rose hips and the preserves (puree

219 veral cancer cell lines, as indicated by the cytotoxic activity of several novel small molecule IAP a

220 gnant cells confirmed the FAO inhibition and cytotoxic activity of ST1326, particularly on acute myel

221 ls, TpeL is a significant contributor to the cytotoxic activity of supernatants from cultures of tpeL

222 or-expressed CCL21 promoted the survival and cytotoxic activity of the adoptively transferred T cells

223 In vitro cytotoxic activity of the essential oil was determined o

224 Notably, the cytotoxic activity of the Fcmu-drug conjugate was mainta

225 ization of the synthetic hexapeptide and the cytotoxic activity of the hexapeptide conjugated to cisp

226 antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent D

227 The cytotoxic activity of the new ruthenium(II) and iridium(

228 The potent cytotoxic activity of the parasite appears to underlie d

229 and immunoassay studies demonstrate that the cytotoxic activity of the prodrug/Pd(0)-resin combinatio

230 Moreover, we have provided evidence that the cytotoxic activity of the proinflammatory cytokine IFN-g

231 A superior cytotoxic activity of the ruthenium complexes as compare

232 T-ALL cohorts, which correlated with similar cytotoxic activity of the SRC inhibitor KX2-391 and inhi

233 profile, antioxidant, anti-inflammatory and cytotoxic activity of the still insufficiently explored

234 a taxol derivative without compromising the cytotoxic activity of the taxol.

235 The cytotoxic activity of the vaccine-induced CTLs was indep

236 How the cytotoxic activity of these myeloid cells is regulated i

237 s in ES NSCLC patients express TNFalpha, the cytotoxic activity of this cytokine may confer improved

238 itro cell viability analysis showed that the cytotoxic activity of TMZ was substantially increased wh

239 osis in colon carcinomas and potentiated the cytotoxic activity of TRAIL in RKO and HT29 cells and th

240 find that this mAb can enhance the in vitro cytotoxic activity of venetoclcax for CLL cells with hig

241 Content in cytolytic granules, as well as cytotoxic activity, of EBV- and CMV-specific CD8(+) T ce

242 The cytotoxic activities on a panel of human tumor cell line

243 PG-1 induces strong cytotoxic activities on cell membrane and acts as a pote

244 e highest antioxidant activity but the least cytotoxic activities on non-tumourous cell lines of NIH/

245 nsport abilities in artificial liposomes and cytotoxic activity on human cancer cell lines.

246 that are responsible for proinflammatory and cytotoxic activity on human vaginal epithelial cells.

247 rary showed an interesting dependency of the cytotoxic activity on the carbohydrate moiety, linker, p

248 intracellular granzyme B and showed stronger cytotoxic activity on the target cells.

249 Puree of R. canina exerted cytotoxic activity only against the HeLa cell line among

250 These defects were not simply due to reduced cytotoxic activity or increased cell death but, rather,

251 cells and, more importantly, sustains their cytotoxic activity over the long-term via persistent blo

252 ates with NEC (n = 14) exhibited significant cytotoxic activity (P = .008), and we identified in all

253 T3L-primed CD8(+) T cells displayed enhanced cytotoxic activity, polyfunctionality, and Ag sensitivit

254 nstrate that neither diminishing NK mediated cytotoxic activity (Prf1 mutation) nor NK cell depletion

255 t regulatory CD56(+)CD3(-) cells exhibit low cytotoxic activity, produce IL-22, and have an expressio

256 A preliminary model to explain the structure-cytotoxic activity relation is proposed where different

257 analogues 32 and 33 exhibit antimalarial and cytotoxic activities stronger than those of the marineos

258 onomeric preparation displayed hemolytic and cytotoxic activities suggesting that the monomer is the

259 ivated, expressed more TRAIL, and had strong cytotoxic activity, suggesting their contribution to the

260 y higher levels of IFN-gamma and had greater cytotoxic activity than did those from TLR4-deficient mi

261 ed with M2 displayed lower degranulation and cytotoxic activity than NK cells cocultured with M1.

262 ations indicating that granzymes possess non-cytotoxic activities that might include such diverse bio

263 264.7 murine macrophage cells have increased cytotoxic activity that is in part mediated by iNOS and

264 ex on different cancer cell lines indicate a cytotoxic activity that is unquestionably derived from t

265 expressing CD4(+) T cells exhibited a strong cytotoxic activity that restricted tumor development.

266 ances monocyte and macrophage phagocytic and cytotoxic activities through enhanced binding to CD16a u

267 Here we show that 8H exerts its cytotoxic activity through disruption of microtubule dyn

268 Both extracts exerted cytotoxic activity through dose-dependent impairment of

269 in IL-15/IL-15Ralpha-IgG1-Fc complex gained cytotoxic activity toward a number of NK-sensitive targe

270 Amph variants have cytotoxic activity toward A-253 carcinoma cells that req

271 At steady state, AT1-ILCs displayed cytotoxic activity toward adipose tissue macrophages (AT

272 K cells from CS-exposed mice exhibit greater cytotoxic activity toward cells that express the NKG2D l

273 have been considered redundant due to their cytotoxic activity toward human neutrophils, each toxin

274 ved drugs were identified that showed potent cytotoxic activity toward retinoblastoma cell lines in v

275 p(-/-) versus wild type mice showed impaired cytotoxic activity toward tumor targets.

276 VLX600 shows enhanced cytotoxic activity under conditions of nutrient starvati

277 , their cell-selective antiproliferative and cytotoxic activities vary significantly.

278 This reduction of NK cytotoxic activity was accompanied by lower expression o

279 Additionally, a clone with low cytotoxic activity was associated with death and poor cl

280 dithiothreitol, indicating that the lack of cytotoxic activity was attributable to the formation of

281 The cytotoxic activity was determined in human cancer cell l

282 Their cytotoxic activity was evaluated according to protocols

283 The cytotoxic activity was evaluated using the MTT assay.

284 the agar disk diffusion method, and in vitro cytotoxic activity was examined by cell proliferation as

285 The peptide's cytotoxic activity was found to be markedly dependent up

286 However, VSV-FH cytotoxic activity was reduced by pretreatment of the ce

287 artially restored by IL-2 treatment, whereas cytotoxic activity was still defective in IL-2-activated

288 severity of illness and treatment modality, cytotoxic activity was strongly and inversely associated

289 Neutrophil cytotoxic activities were reduced in thrombocytopenic an

290 FN-gamma, TNF-alpha, and IL-2 and exhibiting cytotoxic activity, were associated with protection (p <

291 s, as determined by IFN-gamma production and cytotoxic activity, were similar to those obtained from

292 Without cytotoxic activity when administered as a single agent,

293 cription factors is present, but to lose all cytotoxic activity when both are not expressed.

294 identified a set of drugs that had enhanced cytotoxic activity when combined with IRAK inhibition.

295 jacent to the cationic sector exhibited high cytotoxic activity when tested against three different c

296 tics exhibit cytostatic activity rather than cytotoxic activity, which would be more desired.

297 ihydroisocoumarin-truncated analogs lose all cytotoxic activity while retaining the ability to inhibi

298 xtracts and evaluate their antimicrobial and cytotoxic activities with regard to some pathogenic micr

299 In particular, SeChry elicited a noteworthy cytotoxic activity with mean IC50 values 18- and 3-fold

300 racted from HTL-WW expressed potent CHO cell cytotoxic activity, with a LC(50) at 7.5% of HTL-WW.