ライフサイエンスコーパス: cytotoxic effect

1 depend on the presence of oxygen to elicit a cytotoxic effect.

2 cells via RME in the first 24 h period exert cytotoxic effect.

3 ancer cells specifically but also to enhance cytotoxic effect.

4 8 h), and this effect may produce additional cytotoxic effects.

5 malignant T-cell proliferation with minimal cytotoxic effects.

6 e abraded particles did not induce any acute cytotoxic effects.

7 ped from the phagocyte, exerting significant cytotoxic effects.

8 e to penetrate into cells without triggering cytotoxic effects.

9 l of mammalian cells, where they exert their cytotoxic effects.

10 ered aquaporin-0 activity without detectable cytotoxic effects.

11 both fibrils and oligomers and the resulting cytotoxic effects.

12 in NIH3T3 mouse fibroblasts, do not produce cytotoxic effects.

13 (HEK-293T), showing in some cases important cytotoxic effects.

14 il extracellular traps and are known to have cytotoxic effects.

15 t of cells, and inhibition of ABCC5 may have cytotoxic effects.

16 Free heme has proinflammatory and cytotoxic effects.

17 Atg7 can activate autophagy with no apparent cytotoxic effects.

18 dox agents has the potential for devastating cytotoxic effects.

19 f the retinal pigment epithelium and display cytotoxic effects.

20 HCV-specific CD8 T cells with antiviral and cytotoxic effects.

21 group at C44 as a critical feature for PLTXs cytotoxic effects.

22 rted for the latter may be due to off-target cytotoxic effects.

23 re biological functions while preventing its cytotoxic effects.

24 Accumulation of NO may cause cytotoxic effects.

25 an improved physicochemical profile without cytotoxic effects.

26 ving dentin bridge formation without causing cytotoxic effects.

27 coffee infusions at the highest dose without cytotoxic effects (500mug/mL) significantly prevented th

28 Compounds 9c and 9e revealed effective cytotoxic effects after 72 h of incubation in both normo

29 ments demonstrated that mP-PTX has a similar cytotoxic effect against A2780 cells as free PTX and P-P

30 s, AptNAs were demonstrated to have specific cytotoxic effect against leukemia cells.

31 ll extracts showed a phenolic dose-dependent cytotoxic effect against MDA-MB-435, weak activity again

32 he cellular microtubule network, and exert a cytotoxic effect against multiple cancer cell lines.

33 ypes can be added to the list of fruits with cytotoxic effects against breast cancer cells while not

34 Moreover, they have shown strong cytotoxic effects against cancer cell lines.

35 by CCR5-deficient T(reg) or to enhance their cytotoxic effects against CD8(+) T cells.

36 hat FV-specific CD4+ T cells indeed mediated cytotoxic effects against FV epitope peptide loaded targ

37 roliferation of human cancer cells with less cytotoxic effects against normal mouse epidermal cells.

38 lular HDACs in a pan-HDAC assay but enhanced cytotoxic effects against the human cancer cell lines A2

39 rBbKIm shows selective cytotoxic effect and angiogenesis inhibition against pro

40 th Irgafos 168 led to a significantly strong cytotoxic effect and PP prepared with Irganox 1076 induc

41 aBalpha degradation and enhanced Dox-induced cytotoxic effects and apoptosis in all breast cancer cel

42 tion could be detected in samples exhibiting cytotoxic effects and at cytotoxic levels of analyzed es

43 estigate mensacarcin's unique cytostatic and cytotoxic effects and its mode of action.

44 ed Mito-CP and Mito-Q, we evaluated relative cytotoxic effects and mitochondrial bioenergetic changes

45 anocarriers for long periods of time with no cytotoxic effects and no noticeable influence on embryog

46 Cytotoxic effect, apoptosis, oxidative stress, and produ

47 The cytotoxic effect appeared to be mediated by induction of

48 However, their cytotoxic effects are affected by different expression l

49 nosine nucleotides seem to contribute to the cytotoxic effect as well.

50 -tumor antibodies must be optimized for both cytotoxic effects as well as hFcgammaRIIA engagement on

51 Granulysin is the possible mediator of the cytotoxic effect, as the reduced cytotoxic activity agai

52 Hence, we report a new cytotoxic effect associated with intracellular C. neofor

53 opurines for certain diseases is common, the cytotoxic effects associated with chronic exposure to th

54 brils and oligomers assemble and exert their cytotoxic effect at cellular membranes, rather than in b

55 Test compounds showed cytotoxic effects at concentrations comparable to or hig

56 clearly distinguishable from cytostatic and cytotoxic effects at higher drug concentrations and long

57 film formation, namely: initial adhesion and cytotoxic effect, biofilm accumulation, susceptibility t

58 These molecules exert cytotoxic effects by binding to DNA through various mech

59 Indeed, As(2)O(3) exerts its cytotoxic effects by inducing a powerful oxidative stres

60 e persistent organic pollutants which elicit cytotoxic effects by inducing reactive oxygen species ge

61 ) SEL1L down-modulation synergy enhances VPA cytotoxic effects by influencing GSCs proliferation and

62 g., quinazolinediones, QDs) that exert their cytotoxic effects by modulating ROS-mediated cell signal

63 effector of neurotoxicity in AD, might exert cytotoxic effects by reactive oxygen species generation

64 No cytotoxic effects caused by EMD were detected.

65 , all surfaces with ChA residues showed some cytotoxic effect compared with controls (P <0.05).

66 herapy resulted in a significantly increased cytotoxic effect compared with reovirus monotherapy and

67 The cytotoxic effects depend directly on the drug's ability

68 own, that the presented device is capable of cytotoxic effect detection and estimation of cell viabil

69 In addition, the cytotoxic effects, determined as reactive oxygen species

70 tio of the two drugs that exerted equivalent cytotoxic effects differed substantially in samples from

71 sion of LGP2 leads to enhanced IFNbeta, (ii) cytotoxic effects following IR correlated with expressio

72 9 and the parent molecule 1 are similar, the cytotoxic effect for compound 9 was, as planned, markedl

73 delta T cells, however, and to overcome this cytotoxic effect gammadelta T cells were genetically mod

74 wever, inadequate local retention and severe cytotoxic effects have limited the clinical use of ionic

75 OHT) can exert estrogen receptor-independent cytotoxic effects have prompted the initiation of clinic

76 se segments possess different structures and cytotoxic effects, however, both can seed full-length hI

77 ernatin binding and confer resistance to its cytotoxic effects, implicating the adjacent hydrophobic

78 he PD-1/PD-L1 pathways and has antiviral and cytotoxic effects.IMPORTANCE We developed several novel

79 The cytotoxic effect in 0.2mM t-BHP-induced HepG2 cells was

80 ata indicate that PT exhibited a more potent cytotoxic effect in Caco-2 compared to HCT-116 cells.

81 th significant increases of Dox delivery and cytotoxic effect in cancer cells.

82 umulation in photoreceptors can itself exert cytotoxic effect in cones, independently of CNG channel

83 The compound does not exhibit any cytotoxic effect in HEK293 cells and displaces the BRD9

84 ent with propranolol led to a dose dependent cytotoxic effect in hemangioma endothelial cells with de

85 in/GSI combination therapy has a synergistic cytotoxic effect in Notch-dependent tumor cells by enhan

86 elinexor and ibrutinib elicits a synergistic cytotoxic effect in primary CLL cells and increases over

87 al ribonucleotide metabolism to elicit their cytotoxic effects in C. elegans rather than by thyminele

88 lymer demonstrated significant apoptotic and cytotoxic effects in C6 GBM cells.

89 ntrations in tissues, and exhibits selective cytotoxic effects in cancer cells through peroxide forma

90 derlying mechanism(s) by which PT exerts its cytotoxic effects in CRC cells.

91 For example, tamoxifen and OHT exert cytotoxic effects in malignant peripheral nerve sheath t

92 hich LEN, acting through CRBN and IKZF1, has cytotoxic effects in MDS and AML that depend on a calciu

93 BEL showed no detectable cytotoxic effects in mice.

94 eover, lead agent BP-1-108 showed negligible cytotoxic effects in normal bone marrow cells not expres

95 ermine BMP2-induced osteogenic mediators and cytotoxic effects in PDL cells and compare these cells t

96 inhibit human thymidylate synthase (hTS) for cytotoxic effects in single agents.

97 ionic and targets the mitochondria to induce cytotoxic effects in tumor cells, albeit not very effect

98 ith efficient internalization, efficacy, and cytotoxic effects in vitro Pharmacokinetic analyses in m

99 al cycle, which exhibits a broad spectrum of cytotoxic effects in vitro.

100 encing of BARD1beta showed genotype-specific cytotoxic effects, including decreased substrate-adheren

101 platinum resulted in the potentiation of the cytotoxic effect, indicating that macitentan can enhance

102 Immediate cytotoxic effects induced by photoimmunotherapy were cle

103 l treatment, which can integrate with direct cytotoxic effects induced by radiation or chemotherapy t

104 We found that MLN9708 had cytotoxic effects, induced autophagy and MKP-1 expressio

105 of various fibril polymorphs with differing cytotoxic effects is essential for determining how the a

106 hanism of action by which MDA-5 exerts these cytotoxic effects is unclear.

107 eads to increased free FA content, which has cytotoxic effects leading to cell death.

108 The mechanism involved in the cytotoxic effect may be associated with induction of apo

109 To our knowledge this is the first report on cytotoxic effects mediated by chondroitin sulfate/dermat

110 nous histones exacerbates I/R injury through cytotoxic effects mediated by TLR9 and MyD88.

111 f the tumor microenvironment and confirm the cytotoxic effects observed by EMP2 treatment in vivo.

112 The senescence-dependent cytotoxic effect of 11 was also confirmed through phosph

113 The cytotoxic effect of anticancer drugs doxorubicin (DOX),

114 ssibility that Pol lambda could modulate the cytotoxic effect of AraC.

115 d inhibition of JNK activity antagonized the cytotoxic effect of both compounds.

116 otoxicity, and our results demonstrate a new cytotoxic effect of C. neoformans infection on murine ma

117 nsitivity of the ovarian cancer cells to the cytotoxic effect of cDDP by regulating expression of the

118 ort and increased cellular resistance to the cytotoxic effect of copper.

119 apy made tumor cells more susceptible to the cytotoxic effect of CTLs through a dramatic perforin-ind

120 The cytotoxic effect of Cu(CQ) is reproduced in normal human

121 elective dCTPase inhibitors that enhance the cytotoxic effect of cytidine analogues in leukemia cells

122 Here we compare the cytotoxic effect of defined and comparable particle conc

123 The cytotoxic effect of disulfiram was maximal when administ

124 dependent efflux significantly increases the cytotoxic effect of doxorubicin (combination index, <0.9

125 drial MRP-1-dependent efflux activity on the cytotoxic effect of doxorubicin was investigated by coun

126 ntify conditions that enhance or prevent the cytotoxic effect of edelfosine, we have conducted genome

127 In erythrocytes, the cytotoxic effect of HlyA is strongly amplified by P2X re

128 thylates the RNA of Y. ruckeri to reduce the cytotoxic effect of holomycin during holomycin productio

129 ed the concentration-dependent (0.1-1 mg/mL) cytotoxic effect of Ketamine and reflect a loss in expre

130 FNalpha/beta treatment strongly enhances the cytotoxic effect of MEK inhibition, but only in cell lin

131 the efficacy of gene therapy by reducing the cytotoxic effect of misfolded mutant RPE65s.

132 We hypothesized a local cytotoxic effect of NET-related histone release in necro

133 RK) pathway is partially responsible for the cytotoxic effect of phenformin.

134 into how we might measure the genotoxic and cytotoxic effect of plasma jet treatments (both indirect

135 The cytotoxic effect of resveratrol on a breast cancer cell

136 These findings suggest that the direct cytotoxic effect of Shiga toxin 2 in the thalamus might

137 ha5 integrin subunit, thereby increasing the cytotoxic effect of temozolomide.

138 ding the implications of this pathway in the cytotoxic effect of thiopurine drugs necessitates an acc

139 The cytotoxic effect of this mAb was not mitigated when the

140 nsfersome(R) degradation and neutralized the cytotoxic effect of Transfersome(R)-delivered terbinafin

141 f drug treated cells are studied to evaluate cytotoxic effect of ZD6474 and also to assess the freque

142 This enhanced reactivity may underlie the cytotoxic effects of (-)-lomaiviticin A (1).

143 ferent geometries commonly used to study the cytotoxic effects of (64)Cu.

144 a protective mechanism against ROS-triggered cytotoxic effects of a cocktail of pollutants in Caco-2

145 Finally, MBP1 could prevent the cytotoxic effects of Abeta in primary cortical neurons.

146 otecting the photoreceptor cells against the cytotoxic effects of accumulated all-trans-retinal.

147 mitochondrial dysfunction resulting from the cytotoxic effects of accumulated amyloid beta (Abeta).

148 Protection of neurons from cytotoxic effects of activated astroglia by antisense kn

149 encing of Chk2 rescues cancer cells from the cytotoxic effects of apoptin.

150 ADCC assays confirmed the cytotoxic effects of ARGX-111 in multiple human cancer c

151 and primary astrocytes, that the anticancer/cytotoxic effects of ascorbate are completely abolished

152 ion factor may be partly responsible for the cytotoxic effects of BET inhibition in LAC cells, althou

153 RNA targeting TRAF6 were resensitized to the cytotoxic effects of bortezomib due to down-regulation o

154 to 100 nM), prior to injury, attenuated the cytotoxic effects of BSI and preserved neurite length si

155 ted macrophages (TAM) are known to limit the cytotoxic effects of chemotherapy in preclinical models

156 ors suppress cancer cell growth, enhance the cytotoxic effects of cisplatin and inhibit tumour growth

157 omologous DNA repair efficiency and enhanced cytotoxic effects of cisplatin in NSCLC cells.

158 with KT53 show heightened sensitivity to the cytotoxic effects of cisplatin, supporting a role for GS

159 doles show unique behavior by increasing the cytotoxic effects of clinically relevant levels of ioniz

160 ls were able to shield living cells from the cytotoxic effects of CNTs, allowing biofilm formation to

161 Because the cytotoxic effects of conventional chemotherapies often h

162 BER counters the mutagenic and cytotoxic effects of damage that occurs continuously to

163 Ccx-ckr1 gene renders cTECs sensitive to the cytotoxic effects of diphtheria toxin (DT).

164 death, this pathway sensitizes cells to the cytotoxic effects of DNA breaks.

165 utator phenotype and sensitizes cells to the cytotoxic effects of DNA damage.

166 oma were significantly more resistant to the cytotoxic effects of DNA replication stress-inducing dru

167 In addition, AZD3463 enhanced the cytotoxic effects of doxorubicin on NB cells.

168 ontribute significantly to resistance to the cytotoxic effects of EGFR inhibition.Significance: Three

169 s study are to investigate proliferative and cytotoxic effects of EMD on oral epithelial cells and th

170 Cytotoxic effects of EMD treatment were sampled by lacta

171 or elucidating the mechanisms underlying the cytotoxic effects of environmental toxicants.

172 RNA) knockdown of beta-catenin decreased the cytotoxic effects of Enzastaurin plus AR-A014418.

173 Lipotoxicity refers to the cytotoxic effects of excess fat accumulation in cells an

174 NA against autophagy components enhanced the cytotoxic effects of flavopiridol and thapsigargin, but

175 all cell lung carcinoma (NSCLC) cells to the cytotoxic effects of GMX.

176 Direct cytotoxic effects of H2O2 on PC12 in presence and absenc

177 HSP72 by minimizing the cell death caused by cytotoxic effects of heat.

178 oxygenase-1 (HO-1) mediates tolerance to the cytotoxic effects of heme during malarial hemolysis but

179 eased the vulnerability of beta cells to the cytotoxic effects of hIAPP.

180 pha inhibitor protein (IAIP) neutralizes the cytotoxic effects of histones and decreases histone-indu

181 r, the precise role of MSH3 in mediating the cytotoxic effects of ICL-inducing agents remains poorly

182 tumor burden that was not a result of direct cytotoxic effects of IFN-gamma on tumor cells.

183 and ex vivo assays were applied to evaluate cytotoxic effects of IL-1beta on choroidal endothelium.

184 ory cytokines are well characterized, direct cytotoxic effects of invading immune cells on the ischem

185 rowth factor receptor (EGFR) can enhance the cytotoxic effects of ionizing radiation (IR).

186 bition of FGFR1 synergistically enhanced the cytotoxic effects of ionizing radiation and cisplatin.

187 es that pharmacologic ascorbate enhances the cytotoxic effects of ionizing radiation as seen by decre

188 ity of these Au(I)-indoles to potentiate the cytotoxic effects of ionizing radiation.

189 The cytotoxic effects of Ir(III)-PPY nucleoside are both tim

190 removal of AP sites, which may mitigate the cytotoxic effects of IR.

191 st that epigenetic therapies may restore the cytotoxic effects of irradiation in radioresistant CSC p

192 doxorubicin nor mitomycin C potentiated the cytotoxic effects of ischemia.

193 The cytotoxic effects of isofuranodiene towards rat neuronal

194 e attenuated ROS production and reversed the cytotoxic effects of K-Ras(G12V) in the TKO MEFs.

195 FLT imaging can be used to monitor the acute cytotoxic effects of mAb-IR700-induced PIT even before m

196 r subtypes of breast cancer, to validate the cytotoxic effects of MLN9708, alone and in combination w

197 The present study focused on the cytotoxic effects of monoclonal FLCs.

198 r, functional inhibition of SMO enhances the cytotoxic effects of NF-kappaB inhibitor.

199 e and after PIT for monitoring the immediate cytotoxic effects of NIR mediated mAb-IR700 PIT.

200 T P1-1 and MRP1 in protecting cells from the cytotoxic effects of NO.

201 ights into the estrogen receptor-independent cytotoxic effects of OHT by studying how it kills MPNST

202 In this study, we investigated the cytotoxic effects of p28 treatment alone and in combinat

203 These findings provide insight into the cytotoxic effects of PARP inhibition, and point at combi

204 tial of this type of assays by examining the cytotoxic effects of phenylarsine oxide (PAO) and cyclop

205 For monitoring the acute cytotoxic effects of photoimmunotherapy before the tumor

206 ttle research on the potential genotoxic and cytotoxic effects of plasma jet treatment.

207 ADC and v(e) parameters correlated with the cytotoxic effects of platinum-based therapy and may be u

208 injured cells and was protective against the cytotoxic effects of proteasome inhibition.

209 molecular chaperones that protect cells from cytotoxic effects of protein misfolding and aggregation.

210 cervical tumor cells without increasing the cytotoxic effects of radiation on normal human fibroblas

211 ophy and increased hepatocyte sensitivity to cytotoxic effects of saturated fatty acids.

212 ve addressed these unknowns by comparing the cytotoxic effects of sequence variants with differing al

213 Mechanistic studies indicate that the cytotoxic effects of SGN-CD33A involve DNA damage with e

214 Cytotoxic effects of SQ-CDDP NP were assessed in human c

215 mechanisms that enable cells to tolerate the cytotoxic effects of sunitinib.

216 IL-13, as well as IL-4, potentiated the cytotoxic effects of t-butyl hydroperoxide and hydrogen

217 glioblastoma patients as an enhancer of the cytotoxic effects of temozolomide and radiotherapy.

218 lity to protect alpha7-expressing cells from cytotoxic effects of the alpha7 agonist choline in combi

219 to become mature, and thus resistant to the cytotoxic effects of the Bcl-2 inhibitor.

220 sed the in vitro sensitivity of cells to the cytotoxic effects of the chemotherapeutic drug 5-fluorou

221 eration of L-428 and U-HO1 cells and reduced cytotoxic effects of the chemotherapeutical agents gemci

222 Cytotoxic effects of the combination of the food compone

223 tumor ether lipids (L-GAELs) that retain the cytotoxic effects of the D-GAELs including the ability t

224 The cytotoxic effects of the mutant and wild-type proteins w

225 Cytotoxic effects of the PB cocktail occurred at lower c

226 s study provides the first evaluation of the cytotoxic effects of the recently identified palytoxin (

227 ge percentage of tumors are resistant to the cytotoxic effects of the TMZ-induced DNA lesion O(6)-met

228 alities by virtue of diminishing many of the cytotoxic effects of these mutant prion proteins (PrPDel

229 The kinetic, thermodynamic, and cytotoxic effects of these mutations were characterized.

230 ls, which express high levels of AGT, to the cytotoxic effects of this agent under normoxic and oxyge

231 that 5C12 HuMAb effectively neutralizes the cytotoxic effects of this toxin by redirecting its trans

232 Thus, in CLL, the cytotoxic effects of Tnv-6 result from dysregulation of

233 Veliparib increased the cell cycle and cytotoxic effects of topotecan in multiple cell line mod

234 netic stabilizers that rescue cells from the cytotoxic effects of TTR amyloidogenesis.

235 Many studies highlighted the cytotoxic effects of various NP, including titanium diox

236 evidence of EdU uptake, indicating that the cytotoxic effects of vincristine took place during G1 Co

237 dye exclusion and a more efficient specific cytotoxic effect on Caco-2 cells was observed on the cel

238 Specifically, the cytotoxic effect on Caco-2, HeLa (cancer) and MDCK (non-

239 sosomal iron that is utilized by ART for its cytotoxic effect on cancer cells.

240 with anticancer drug ZD6474 to evaluate the cytotoxic effect on cellular electrical behaviour using

241 sulfate GAGs derived from HCC70 cells had a cytotoxic effect on HCC70 cells and CCD-1095Sk cells.

242 umab, hSGZ showed an additive or synergistic cytotoxic effect on HER2(+)/Fn14(+) breast cancer cell l

243 rized myeloid cell supernatants had a direct cytotoxic effect on human A2B5(+) neural progenitors, re

244 We conclude that EA has a potent cytotoxic effect on human synovial sarcoma cells which i

245 of tumor cells within the bone marrow and a cytotoxic effect on isolated cells due to the high LET (

246 The in vitro cytotoxic effect on malignant T cells is further validat

247 bitory concentration, FIT-039 did not have a cytotoxic effect on mammalian cells.

248 in enhanced proteasome inhibition and robust cytotoxic effect on MM cells when BTZ was administered t

249 , these results show that DD exerts a potent cytotoxic effect on NK cells, a phenomenon that might im

250 Ad5Delta24 exerted a potent, dose-dependent, cytotoxic effect on tumor cells, whereas CAR-T cells spe

251 apsulated doxorubicin and paclitaxel exhibit cytotoxic effects on 4T1 and PC3-luc cells, respectively

252 rain K279a, as well as the morphological and cytotoxic effects on A549 cells.

253 ichia coli, and Staphylococcus aureus; their cytotoxic effects on A549, NCI-H441, small airway epithe

254 Paralleling its cytotoxic effects on breast cancer cells, PEDF also exer

255 ical assays of these novel structures showed cytotoxic effects on different cancer cell lines.

256 Although direct cytotoxic effects on endothelial cells by Stx are the pr

257 e insight into why NO. may exert more severe cytotoxic effects on fast growing cells, providing an im

258 ng in combination with imatinib had additive cytotoxic effects on GIST882 cells.

259 Resolvin D1 had no cytotoxic effects on HGFs at concentrations between 1 an

260 ey are biocompatible and show no evidence of cytotoxic effects on hMSCs.

261 in that contributes to virulence through its cytotoxic effects on intestinal epithelial cells.

262 uggesting that OXi4503 also exhibited direct cytotoxic effects on leukemia cells.

263 est compounds plus 1 mug/ml LPS exhibited no cytotoxic effects on macrophage cells.

264 ion in adjacent pancreatic islets and direct cytotoxic effects on pancreatic islets.

265 rther show that in vitro TERT inhibition has cytotoxic effects on primary ALM cells.

266 PhIP and PhIP@OA did not show significant cytotoxic effects on SHSY5Y, MRC5, and human dermal fibr

267 mouse epididymal lumen without any apparent cytotoxic effects on spermatozoa and that these structur

268 The essential oils showed cytotoxic effects on tested human tumor cell lines, rela

269 ion-associated gene 7 (MDA-7/IL-24) exhibits cytotoxic effects on tumor cells while sparing untransfo

270 ic doses of GC induce growth-suppressive and cytotoxic effects on various leukocytes including B cell

271 Thus, sodium arsenite may confer its cytotoxic effect partly through the aberrant activation

272 gested that thiopurine drugs may exert their cytotoxic effects partly through binding of (S)GTP to a

273 Our data indicate that, independent of its cytotoxic effects, PVL also plays an important and posit

274 To exert its cytotoxic effect, STx invades cells through retrograde m

275 ngly, tyramine had a stronger and more rapid cytotoxic effect than histamine.

276 and histamine was associated with a stronger cytotoxic effect than was treatment with either BA or on

277 s displayed comparable antiproliferative and cytotoxic effects than the native doxorubicin because of

278 inosa infection through its ability to exert cytotoxic effects that interrupt T3S translocation and P

279 with these delivery benefits, PBAE exhibited cytotoxic effects that presented an engineering challeng

280 To exert their cytotoxic effect, these prodrugs need to be metabolicall

281 Selectivity against PV over cytotoxic effects to HeLa cells was >100-fold after incu

282 Stem and leaf callus extracts exerted cytotoxic effects towards CCRF-CEM cells (stem: 13.1+/-0

283 son and the observed differences between the cytotoxic effects under microfluidic and static conditio

284 fic xenobiotic receptor inhibitor and has no cytotoxic effects up to 30 microM; 2) inhibits CAR-media

285 unds (HMF and furfural F) and cytoprotective/cytotoxic effects upon Caco-2 cells (MTT, cell cycle and

286 lines are in the range of 25-45 muM, and no cytotoxic effect was observed on nontumorigenic (HEK-293

287 No cytotoxic effect was observed when bronchial epithelial

288 This cytotoxic effect was reversed by catalase, but not super

289 This cytotoxic effect was VEGF (vascular endothelial growth f

290 adhered to HeLa cells at low densities, and cytotoxic effects were discrete, supporting the view tha

291 LC50 = 47 +/- 8 muM), whereas no significant cytotoxic effects were observed for DPHP concentrations

292 No cytotoxic effects were observed in treated cells up to 0

293 Cytotoxic effects were observed only in CEH exposed to 5

294 y, NK cells were highly resistant to the TKI cytotoxic effect, were properly activated by immunostimu

295 eeding polyglutamine aggregation and exhibit cytotoxic effects when applied to neuronal cells.

296 primary patient blasts and observed superior cytotoxic effects when compared with other available FLT

297 nd that extracellular ATP itself has a small cytotoxic effect, whereas adenosine formed from ATP degr

298 vative and paclitaxel produced a synergistic cytotoxic effect, which was paralleled by an enhanced ap

299 /cytotoxicity assays indicate dose-dependent cytotoxic effects, which are inhibited by the nitric oxi

300 rate that the chemotherapy agent retains its cytotoxic effect, while the antibody maintains the abili