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1 dUTP nick end labeling (TUNEL) staining also revealed on
2 in immunoprecipitation assay using biotin-16-dUTP and terminal deoxynucleotide transferase showed tha
3 nucleotide analogues (dGTP-PC-Bodipy-FL-510, dUTP-PC-R6G, dATP-PC-ROX, and dCTP-PC-Bodipy-650) (PC, p
5 , single-step closed-system assay and uses a dUTP/uracil DNA glycosidase anti-PCR contamination contr
8 ally undemanding azide analogue of dTTP (AHP dUTP) with an alkyl chain and ethynyl attachment to the
9 cleavable fluorescent nucleotide, 3'-O-allyl-dUTP-PC-Bodipy-FL-510 (PC-Bodipy, photocleavable 4,4-dif
12 eavable (PC) biotinylated nucleotide analog, dUTP-PC-Biotin, for DNA polymerase extension reaction to
16 e transcriptase discriminates poorly between dUTP and dTTP, and accordingly, viral DNA products becom
17 deoxynucleotidyl transferase-mediated biotin-dUTP nick-end labeling (TUNEL), observations that are in
18 deoxynucleotidyl transferase-mediated biotin-dUTP nick-end labeling staining to quantitate myocyte ap
19 Terminal deoxynucleotidyl transferase biotin-dUTP nick end labeling (TUNEL) assay was performed to de
21 terminal deoxynucleotidyl transferase biotin-dUTP nick end labeling, immunoblot analysis and quantita
22 ed mucosal injury, TUNEL (transferase biotin-dUTP nick end-labeling)-positive cells, neutrophil infil
23 ucleotidyl transferase-mediated biotinylated dUTP nick end labeling)-staining labeled dying cells.
25 -MS/MS study revealed that the non-canonical dUTP concentration (2.9 mum) is approximately 60 times h
26 resented demonstrates that the non-canonical dUTP was abundant relative to TTP, and efficiently incor
27 or TTP over dUTP, implying that the cellular dUTP/TTP ratio determines the frequency of HIV-1 RT-medi
28 veloped a model system in which the cellular dUTP:dTTP ratio can be pharmacologically increased to fa
30 rified and non-target transcripts containing dUTP degraded by Uracil DNA glycosylase, leaving only th
31 genomic DNAs with fluorescently labeled Cy3-dUTP and potentially be useful for diagnostic applicatio
32 tage of terminal deoxynucleotidyltransferase dUTP nick end label (TUNEL)-positive macrophages in the
33 osis by terminal deoxynucleotidyltransferase dUTP nick end-labeling (TUNEL) in myocardial samples fro
36 rescent terminal deoxynucleotidyltransferase dUTP-biotin nick end labeling (TUNEL) assay revealed tha
37 e) for their natural substrates (8-oxo-dGTP, dUTP, dITP, 2-oxo-dATP), which allows them to select the
39 ed DNA is directly labelled with digoxigenin-dUTP near the sites of its initiation in a cell-free sys
40 ng the Cap finder approach, another distinct dUTP containing adapter is added to the 3' end of the ne
42 unodeficiency virus, also displays efficient dUTP incorporation in the dNTP/dUTP pools found in macro
43 the virus-infected cells contained elevated dUTP levels, reverse transcription was found to proceed
44 can be pharmacologically increased to favor dUTP incorporation, allowing dissection of this innate i
46 ort that the virus also encodes a functional dUTP triphosphatase, means that PBCV-1 is the first viru
48 hough monocyte-derived macrophages have high dUTP levels, these cells have low hUNG activity, which m
49 utants of Escherichia coli fail to hydrolyze dUTP and thus incorporate uracil into their DNA, sufferi
50 to cleave the dUTP analogue alpha,beta-imido-dUTP, containing the imido linkage usually regarded to b
53 rates that HIV-1 RT efficiently incorporates dUTP in the macrophage nucleotide pools but not in the T
56 g reverse transcription and does not involve dUTP incorporation, indicating it results from bRT-catal
58 erminal deoxynucleotidyltransferase-mediated dUTP nick end labeling (TUNEL) staining, DNA fragmentati
59 erminal deoxynucleotidyltransferase-mediated dUTP nick end labeling (TUNEL), and was not seen in norm
60 erminal deoxynucleotidyltransferase-mediated dUTP nick end labeling and a marked depletion of oligode
62 erminal deoxynucleotidyltransferase-mediated dUTP nick end labeling, caspase 3 cleavage, and re-local
63 erminal deoxynucleotidyltransferase-mediated dUTP nick end labeling-positive myonuclei, and activated
65 erminal deoxynucleotidyltransferase-mediated dUTP nick end labeling-positivity) and oxidative stress
66 erminal deoxynucleotidyltransferase-mediated dUTP nick end-labeling staining following TNF-alpha.
67 erminal deoxynucleotidyltransferase-mediated dUTP nick-end labeling positive CM (-44%, P<0.01), incre
69 erminal deoxynucleotidyltransferase-mediated dUTP nick-end labeling, and DNA laddering, which were as
70 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL) and fluorescence-a
71 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL) assay suggested th
72 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL) assay, compared to
73 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL) assays, and transm
75 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL) staining character
76 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL) staining of intest
77 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL) staining with GFP.
78 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL) staining, but not
79 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL) staining, indicati
81 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL)-positive cells in
82 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL)-positive myocytes
83 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling and caspase 3 and Bax expr
84 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling and hallmarks of apoptosis
85 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling and trypan blue exclusion
86 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling assay following treatment
87 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling of DNA double-strand break
88 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling staining of lung tissue sa
89 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling) assay determined that con
90 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling, and Rad51) at the leptote
91 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling-positive cells were presen
92 erminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling-positive parasites followi
94 erminal deoxynucleotidyltransferase-mediated dUTP-tetramethylrhodamine nick end labeling assay, demon
96 deoxynucleotidyl transferase (TdT)-mediated dUTP-biotin nick end labeling) assays demonstrate that g
97 with standard markers including TdT-mediated dUTP biotin nick-end labeling and cleaved caspase 3 immu
101 e of cornification, assessed as TdT-mediated dUTP nick end-labeling-positive cells in stratum granulo
103 irth (BrdU labeling) and death (Tdt-mediated dUTP-biotin nick end labeling) to investigate the specif
104 ne transferase (ALT), necrosis, TdT-mediated dUTP-digoxigenin nick-end labeling (TUNEL) staining, cas
105 terminal deoxynucleotide tranferase-mediated dUTP nick-end labeling assay, and ex vivo via Western an
106 terminal deoxynucleotide tranferase-mediated dUTP nick-end labeling staining and immunohistochemistry
107 rminal deoxynucleotidyl transferase mediated dUTP nick end labeling (TUNEL) assay and caspase-3 activ
109 rminal deoxynucleotidyl transferase mediated dUTP nick end labeling, or TUNEL, staining, respectively
110 ase (terminal uridylyl transferase) mediated dUTP-dependent U-insertion/U-deletion cycle may be a pos
112 rminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay and caspase-3 activ
113 rminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) staining, and Western blo
114 rminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL)-positive nuclei, only 6 a
115 rminal deoxynucleotidyl transferase-mediated dUTP nick end labeling analyses indicated a greater numb
116 al deoxyribonucleotidyl transferase-mediated dUTP nick end labeling analysis shows that there is no i
117 minal deoxynucledotidyl transferase-mediated dUTP nick end labeling and CD31 to assess apoptotic inde
118 al deoxyribonucleotidyl transferase-mediated dUTP nick end labeling assay, was preceded by loss of mi
120 rminal deoxynucleotidyl transferase-mediated dUTP nick end labeling assays on tissue sections reveale
122 al deoxyribonucleotidyl transferase-mediated dUTP nick end labeling staining was done to quantify apo
123 al deoxyribonucleotidyl transferase-mediated dUTP nick end labeling staining, was increased in cells
126 rminal deoxynucleotidyl transferase-mediated dUTP nick end labeling) demonstrated that lack of p53 is
128 al deoxyribonucleotidyl transferase-mediated dUTP nick end labeling- and caspase 3-stained cells at 6
129 rminal deoxynucleotidyl transferase-mediated dUTP nick end labeling-positive apoptotic cells (8.3% +/
131 rminal deoxynucleotidyl transferase-mediated dUTP nick end labeling-positive cells and expression of
132 els of active caspase-3/transferase-mediated dUTP nick end-labeling (TUNEL) apoptotic markers and enh
134 minal deoxy-nucleotidyl transferase-mediated dUTP nick end-labeling staining and caspase-3 activity a
136 erminal deoxynucleotide transferase-mediated dUTP nick end-labeling, and single-cell gel electrophore
139 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) and an 11-fold increase i
140 , terminal deoxyribosyl transferase-mediated dUTP nick-end labeling (TUNEL) assay, and real-time RT-P
142 erminal deoxynucleotide transferase-mediated dUTP nick-end labeling (TUNEL) assay; (2) frequencies of
143 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) for fixed tissues and acr
144 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) staining for intratumoral
145 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL), Ki-67, p53, bcl-2, and M
146 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL)-positive cells, NASH, and
149 ion, induced apoptosis (transferase-mediated dUTP nick-end labeling [TUNEL]) and decreased proliferat
150 palmitate on apoptosis (transferase-mediated dUTP nick-end labeling [TUNEL]), mitochondrial death pat
151 erminal deoxynucleotide transferase-mediated dUTP nick-end labeling analysis showed significantly dec
152 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling and caspase-3, indicating that TX
154 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling and in situ oligo ligation method
155 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling and quantified by both caspase-3
156 beta-cell apoptosis [by transferase-mediated dUTP nick-end labeling assay and Western blotting for po
157 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling assay was performed, and intestin
159 rminal deoxynucleotidyl-transferase-mediated dUTP nick-end labeling assay, we showed that the express
163 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling positive nuclei and DNA fragmenta
164 droxydeoxyguanosine and transferase-mediated dUTP nick-end labeling positivity and also prevented ace
165 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling positivity, superoxide, and nitri
166 erminal deoxynucleotide transferase-mediated dUTP nick-end labeling reaction) and involve disruption
167 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling stain) activity was biphasic.
169 erminal deoxynucleotide transferase-mediated dUTP nick-end labeling staining, caspase-3 activity, and
171 ed the number of TUNEL (transferase-mediated dUTP nick-end labeling)-positive capillary cells and ace
173 al deoxyribonucleotidyl transferase-mediated dUTP nick-end labeling, and CD31 immunohistochemistry, r
175 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling, and Ki-67 immunoreactivity were
176 crease in the number of transferase-mediated dUTP nick-end labeling-positive capillary cells, acellul
177 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling-positive cells in FECD samples.
178 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling-positive cells were also increase
179 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling-positive cells, TNF-alpha release
180 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling-positive endothelial cells and pe
181 lded reduced apoptosis (transferase-mediated dUTP nick-end labeling-positive insulin-positive cells;
182 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling-positive microvascular cell numbe
183 rminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling-positive, and exhibited elevated
185 rminal deoxynucleotidyl transferase-mediated dUTP nick-end-labeling analysis reveals greater abundanc
186 rminal deoxynucleotidyl transferase-mediated dUTP nick-end-labeling assay showed no significant apopt
187 rminal deoxynucleotidyl transferase-mediated dUTP-biotin end labeling and activated caspase-3 immunoh
188 rminal deoxynucleotidyl transferase-mediated dUTP-biotin end labeling staining of the increased conce
189 rminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling assay and Hoechst staining
190 rminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end-labeling assay demonstrated that Bo
192 feeding also increased transferase-mediated dUTP-biotin nick-end labeling-positive cells, caspase-3
193 rminal deoxynucleotidyl transferase-mediated dUTP-digoxigenin nick end labeling (TUNEL) were evaluate
194 rminal deoxynucleotidyl transferase-mediated dUTP-digoxigenin nick end labeling (TUNEL), and caspase-
196 (S)-alpha-tert-Butyl-2-nitrobenzyloxy]methyl-dUTP (dU.V) was identified as an efficient reversible te
197 single uracil opposite an adenine (to mimic dUTP misincorporation during DNA synthesis) or a guanine
198 dified nucleotides, a C5-imidazolyl-modified dUTP and 3-(aminopropynyl)-7-deaza-dATP were used in pla
199 ion experiment comparing the use of modified dUTP derivatives with TTP for selecting aptamers to a pr
203 sence of high concentrations of noncanonical dUTP, apolipoprotein B mRNA-editing, enzyme-catalytic, p
206 n macrophages, whereas the concentrations of dUTP and TTP in dividing human primary lymphocytes are v
207 the presence of increasing concentrations of dUTP or by infecting with virus that contains the cytosi
211 we study the dUTPase-catalyzed hydrolysis of dUTP, an incorrect DNA building block, to elaborate the
212 oxic U*A pairs arising from incorporation of dUTP in DNA, and for increasing immunoglobulin gene dive
215 this study was to assess the involvement of dUTP binding and dUTPase activity in derepression by Dut
216 by oxaliplatin promoted increased levels of dUTP that was enhanced by subsequent addition of fluorop
217 d macrophages (MDMs) contains high levels of dUTP, which is incorporated into HIV-1 DNA during revers
218 ndk and genes involved in the metabolism of dUTP, a potentially mutagenic precursor of thymidine bio
219 ues yielded after either misincorporation of dUTP during replication or deamination of cytosine.
220 -alpha was associated with higher numbers of dUTP-biotin nick end labeling-positive renal tubule cell
221 state and steady state kinetic parameters of dUTP incorporation reveals minimal selectivity of HIV-1
223 ne depletion is a sharp rise in the ratio of dUTP to dTTP and subsequent incorporation of dUTP into D
225 of thymidylate synthase and increased use of dUTP in place of TTP during DNA replication, with subseq
226 the Duts derepress the SaPI cycle depends on dUTP and involves both motifs V and VI, as we have previ
227 minimal selectivity of HIV-1 RT for TTP over dUTP, implying that the cellular dUTP/TTP ratio determin
228 n of uracil DNA-glycosylase or by preventing dUTP production via inactivation of dCTP deaminase.
234 ayer were studied by morphology and terminal dUTP nucleotide end labeling analyses, respectively.
236 etinal cell death was determined by terminal dUTP nick-end labeling assay; BRB function by quantifyin
239 en and Ki-67 and low positivity for terminal dUTP nick-end labeling indicated robust cell proliferati
240 monstrated by immunohistochemistry, terminal dUTP nick-end labeling, and DNA agarose gel electrophore
241 topathologic analysis that included terminal dUTP nick end-labeling (TUNEL), capillary and cardiomyoc
242 ctive effects, as evidenced by less terminal dUTP nick end-labeling staining, a lower incidence of DN
243 accompanied by enhanced numbers of terminal dUTP nick-end labeling-positive cells at days 4, 6, and
244 ost fertilization (hpf) through the terminal dUTP transferase-mediated nick end-labeling (TUNEL) assa
246 in the retina were quantified using terminal dUTP nick-end labeling (TUNEL) and active caspase-3 (CM-
247 ereas apoptosis was quantified with terminal dUTP nick end labeling (TUNEL) and fluorescence microsco
248 hows the capability of dUTPase to cleave the dUTP analogue alpha,beta-imido-dUTP, containing the imid
249 od's performance and ease, we identified the dUTP second-strand marking and the Illumina RNA ligation
250 ent with the proposed alternative model, the dUTP inhibits rather than inducing the process, as we ha
251 th primer extension product, with all of the dUTP derivatives tested giving yields similar to those o
254 ated by terminal deoxynucleotide transferase dUTP nick end labeling staining and cleaved caspase-3 ex
256 ted by terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) and used to estimate the
259 ly for terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) or activated-caspase 3, s
261 xin V, terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL), 3-(4,5-dimethylthiazol-2
262 d with terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL)-positive soma and the eve
263 tosis (terminal deoxynucleotidyl transferase dUTP nick end labeling [TUNEL] assay), and of collagen t
265 ase in terminal deoxynucleotidyl transferase dUTP nick end labeling and cleaved caspase-3 positive ce
266 y, and terminal deoxynucleotidyl transferase dUTP nick end labeling assay was used to assess alveolar
267 se and terminal deoxynucleotidyl transferase dUTP nick end labeling of targeted doxorubicin micelles
268 is via terminal deoxynucleotidyl transferase dUTP nick end labeling staining and caspase-3 activation
269 ect to terminal deoxynucleotidyl transferase dUTP nick end labeling staining for apoptotic DNA fragme
270 TUNEL (Terminal deoxynucleotidyl transferase dUTP nick end labeling) assay indicated that apoptosis w
271 n, and terminal deoxynucleotidyl transferase dUTP nick end labeling), and diminished Akt phosphorylat
272 4) and terminal deoxynucleotidyl transferase dUTP nick end labeling-positive nuclei (4+/-3% versus 10
273 TUNEL [terminal deoxynucleotidyl transferase dUTP nick end labeling])-positive cells) of NPIs compare
274 tosis (terminal deoxynucleotidyl transferase dUTP nick end labelingc cells), and caspase-8 activity w
275 sed by terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) and measurement of outer
276 ntense terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) signals were found at E16
277 re was terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) staining in vascular cell
278 red by terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) staining, circulating lev
281 sed by terminal deoxynucleotidyl transferase dUTP nick-end labeling assay and activated caspase-3 sta
282 ining, terminal deoxynucleotidyl transferase dUTP nick-end labeling assay, and electron microscopy in
283 s were terminal deoxynucleotidyl transferase dUTP nick-end labeling positive, suggesting remodeling i
285 ty and terminal deoxynucleotidyl transferase dUTP nick-end labeling staining were tested for apoptosi
286 evels, terminal deoxynucleotidyl transferase dUTP nick-end labeling staining, cytochrome c release, t
287 red by terminal deoxynucleotidyl transferase dUTP nick-end labeling, was significantly decreased in t
290 ase in terminal deoxynucleotidyl transferase dUTP nick-end labeling-positive enterocyte nuclei in the
292 nd the terminal-deoxynucleotidyl transferase dUTP-linked nick-end labeling (TUNEL) procedure determin
293 h, as judged by lack of terminal transferase dUTP nick end labeling (TUNEL) labeling or reactivity to
294 ntified apoptosis using terminal transferase dUTP nick end labeling and active caspase-3 staining in
295 apoptosis (detected by terminal transferase dUTP nick-end labeling [TUNEL]) and formation of acellul
296 with EAU, by using the terminal transferase dUTP nick-end labeling assay and polymerase chain reacti
297 nsferase-mediated deoxyuridine triphosphate (dUTP) nick end-labeling (TUNEL) assay were conducted to
298 incorporating dUTP is achieved by PCR, using dUTP-containing primers complimentary to the adapter seq
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