ライフサイエンスコーパス: dampening of

1 ese mice, the D299A mutation caused a global dampening of Aire's transcriptional impact, resulting in

2 cells in GBs is thought to contribute to the dampening of antitumor immunity.

3 Cs supported IL-10 production and subsequent dampening of antiviral T cell responses.

4 anti-B cell therapy may provide a temporary dampening of autoimmune processes through B cell depleti

5 d to reverse disease upon adjuvant-dependent dampening of autoimmunity.

6 sponsive reporter DR5::GUS suggests that the dampening of auxin responses in the stigma epidermis pro

7 Dampening of beta(2) -integrin function of eosinophils i

8 results appear to challenge the notion that dampening of betaAR signaling in the failing heart is pr

9 activation of GIRK channels, leading to the dampening of both spindle-like and epileptiform thalamic

10 egulatory T cells ("suppression") and direct dampening of CD4(+) T cell reactivity ("tuning").

11 cellular redistribution resulted in a global dampening of cell responsiveness, as illustrated by redu

12 cation correlates temporally with the stable dampening of chemotaxis that is indicative of long-term

13 This interaction correlates with a dampening of cIAP1 to polyubiquitinate NEMO and to activ

14 tiation of the strongest sensory input and a dampening of cortical inhibition over the BLA, thus augm

15 el of PTGS2 transcription, consistent with a dampening of COX-2 expression in chronic periodontitis.

16 ection of amoebae, growth within lung cells, dampening of cytokines, and tissue destruction.

17 The resultant long-term dampening of dopamine neuron excitability may serve to t

18 mitant with effector binding nucleate global dampening of dynamics.

19 otic period of 4-5 years, with a progressive dampening of epizootic size and progressive decrease in

20 e between proinflammatory mechanisms and the dampening of excessive immune activation is critical for

21 ed a low ongoing firing rate, due in part to dampening of excitability by a tonic inhibitory conducta

22 Dampening of Fyn kinase activity also inhibited RhoA act

23 lved in bone formation through NMP4-mediated dampening of Gadd34 and c-Myc expression.

24 These effects range from dampening of glutamate release from excitatory terminals

25 signaling pathway defined by NLRP12-mediated dampening of host immune defenses that could be exploite

26 vious data indicate that UPEC promotes local dampening of host innate immune responses.

27 eported in this model, in conjunction with a dampening of host mononuclear cell responses, including

28 by DC of IL-17A-inhibiting cytokines and the dampening of IL-1beta and IL-23.

29 Further studies of CCR5 antagonists in the dampening of immune activation associated with HIV infec

30 in-2-producing CD4(+) cells, consistent with dampening of immune responses.

31 arance, inhibition of protease activity, and dampening of inflammatory cell recruitment.

32 rt that STAT3 plays a key role in amino acid dampening of insulin signaling in hepatic cells.

33 These findings suggest that a dampening of insulin-induced phosphorylation of AS160 on

34 ression under Th17-inducing conditions, with dampening of intracellular AKT phosphorylation.

35 d conformations was further confirmed by the dampening of its amplitude upon covalent substrate trapp

36 the capsid is elicited, as well as a general dampening of its breathing motions.

37 tion of FoxO3 from nucleus to cytoplasm with dampening of its transcriptional program, including anti

38 expression of interleukin-10 and an eventual dampening of LPS-mediated cytokine production in macroph

39 Disruption of this normal homeostatic dampening of lung inflammation results in increased resi

40 Ultimately, a reduction in LC3 flux and dampening of macroautophagy are observed in dendritic ce

41 eal a novel mechanism in which IL-6-mediated dampening of macrophage activation protects tissues from

42 diurnally oscillating light stimulus caused dampening of maximal Lhcb mRNA accumulation levels, with

43 ion to advanced fibrosis was associated with dampening of metabolic, oxidative stress and cell stress

44 bition of the dynein-NCAM180 interaction, or dampening of microtubule dynamics with low dose nocodazo

45 reduction in systemic cytokine release with dampening of myocardial inflammation, injury, and apopto

46 t firing rate activity, pacing, and critical dampening of neuronal circuits.

47 se behavioral effects were associated with a dampening of neuronal excitability in the basolateral am

48 rectionally altered through amplification or dampening of post-trial activity decay through simulated

49 nuate autoimmunity likely occurs through the dampening of pro-inflammatory signals upon engulfment of

50 Augmentation or dampening of proinflammatory responses can be of value i

51 g an immunoregulatory network leading to the dampening of proinflammatory responses, expansion of typ

52 Moreover, the magnitude of dampening of repressor dynamics tracks with the magnitud

53 Mechanical dampening of resonant oscillations due to the presence o

54 plasmid pXO1 and pathogenicity may require a dampening of sporulation regulation by mutational select

55 eparation and execution leads to a transient dampening of STN oscillations, hence facilitating moveme

56 cuate nucleus (ARC) neurons, in concert with dampening of suprachiasmatic nucleus (SCN) circadian rhy

57 t provide a homeostatic mechanism for global dampening of synaptic strength following heightened neur

58 The dampening of T cell immunity was due to the defective pr

59 tivation and a consequential DUSP4-dependent dampening of TCR signaling.

60 Time-dependent dampening of TH activity during the day reverses manic-r

61 f retinogeniculate synaptic transmission and dampening of thalamocortical output was mimicked by teta

62 ctivated factor VIII (FVIIIa) resulting in a dampening of the activity of the activated factor X-gene

63 effects were mediated, at least in part, by dampening of the antigen-specific immunosuppressive func

64 pathway in cardiac failure, contributing to dampening of the beta-adrenergic response.

65 facilitation of growth in epithelia, and the dampening of the chemokine and cytokine output from infe

66 correlation with pain affect may result from dampening of the effective connectivity of the midbrain-

67 the metabolic alterations, which resulted in dampening of the excessive cytokine production.

68 aS and forskolin), suggesting a compensatory dampening of the G protein-adenylyl cyclase system in th

69 hat CpG-induced immune regulation leads to a dampening of the host immune response and healing in the

70 injury-induced induction of HSP72; and that dampening of the HSP72/HSP25 response and ablation of th

71 ith containment of the organism and apparent dampening of the inflammation of host tissue.

72 Successful commensalism requires dampening of the inflammatory response and evasion of ho

73 activation secondary to loss of Cav1 signals dampening of the innate immune response to lipopolysacch

74 EB2A-dependent pathway and that constitutive dampening of the InsP(3) signal reveals unanticipated in

75 culogenic mimicry patterns is accompanied by dampening of the invasive and metastatic uveal melanoma

76 nic activation of one (PI3K/PKB) can lead to dampening of the other (ERK1/2), reducing the mitogenic

77 tress in these areas, but there was a slight dampening of the response in ADX/B animals.

78 ate production of IFN-gamma and a consequent dampening of the Th1 as well as the Th17 effector respon

79 rment in Foxp3 induction was part of a broad dampening of the typical T reg transcriptional signature

80 hat the rhythm can persist after substantial dampening of their activity.

81 targets within coding regions; however, the dampening of these effects by translation likely account

82 Dampening of TLR2 signaling does not require viable M. t

83 Dampening of TNF-RII or TNF-RI+RII leads to a stage-inde

84 ltration, downregulation of cilia genes, and dampening of type 2 inflammation.

85 This lack of dampening of vibrational forces may partially explain wh

86 of particular visual stimuli, resulting in a dampening of visual processing and concomitant positive

87 Continent-scale dampening of vole population cycles, keystone herbivores