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1 rease in SIRT1-MTORC2 interaction and RICTOR deacetylation.
2 methylation, histone methylation, or histone deacetylation.
3 d repressed transcription of Il6 via histone deacetylation.
4 regulation of alternative splicing via Sam68 deacetylation.
5 ular redox potential via HDAC3-mediated PGK1 deacetylation.
6 romotes HDAC3-PGK1 interaction and PGK1 K220 deacetylation.
7 gulation of BA homeostasis by persistent FXR deacetylation.
8 o lysozyme leads to additional peptidoglycan deacetylation.
9 esis, and bile acid (BA) homeostasis through deacetylation.
10  Sin3b decreases Myc protein levels upon Myc deacetylation.
11 ion of p53 by decreasing SIRT2-dependent p53 deacetylation.
12 tial regulation of epigenetic acetylation or deacetylation.
13 itors both induced BRM as well as caused BRM deacetylation.
14 and without splitomicin inhibition of lysine deacetylation.
15 y in part by regulating PDH function through deacetylation.
16 pigenetic modifications that include histone deacetylation.
17  lower molecular weight and higher degree of deacetylation.
18 e p53 protein and modulates p53 activity via deacetylation.
19 ivating AMPK through mechanisms that include deacetylation.
20 ck protein 70 family proteins, causing their deacetylation.
21 rectly interacts with STAT3 and promotes its deacetylation.
22 ondria and unexpectedly is a target of SIRT1 deacetylation.
23 ed and that HDAC6 promotes ERK1 activity via deacetylation.
24 nism for SIRT3 regulation via SIRT1-mediated deacetylation.
25 s required to achieve locus-specific histone deacetylation.
26 f non-coding RNA silencing and histone H4K16 deacetylation.
27 s resulted from successive deiodinations and deacetylations.
28 etyltransferases (HATs) are involved in MSH2 deacetylation/acetylation is unknown.
29 her posttranslational modifications, such as deacetylation/acetylation, methylation, and ubiquitinati
30                             Nonetheless, the deacetylation activity by HDAC3 in the complex was evide
31                                              Deacetylation activity of certain sirtuins was detected
32 inyl-lysine modifications is superior to its deacetylation activity.
33 tain free fatty acids (FFAs) could stimulate deacetylation activity.
34 , which then releases SIRT1 and enhances its deacetylation activity.
35 a new mechanism by which dynamic acetylation/deacetylation acts as a rheostat to fine-tune Aurora B a
36 -modifying enzymes with activities in lysine deacetylation, adenosinediphospho(ADP)-ribosylation, and
37 logical SIRT1 activators that promoted HDAC1 deacetylation also reduced DNA damage in two mouse model
38                        Inhibition of histone deacetylation altered the dynamics of CSB assembly, sugg
39  demonstrate that SIRT1 induction causes the deacetylation and activation of FOXO3a in NAc, which lea
40                           The SIRT2-mediated deacetylation and activation of G6PD stimulates PPP to s
41  of SIRT1 on gene expression are mediated by deacetylation and activation of peroxisome proliferator
42 AMPK and SIRT1 in skeletal muscle leading to deacetylation and activation of PGC-1alpha, increased mi
43 imal structural elements required for lysine deacetylation and catalytic activation by small molecule
44 eate a hitherto-unknown mechanism of protein deacetylation and deacetylimination catalyzed by lysyl o
45  actions that contribute to podocyte protein deacetylation and degradation as well as renal dysfuncti
46 on, whereas Sin3b overexpression induced Myc deacetylation and degradation.
47  triggered by Lsd1-Mi2/NuRD-mediated histone deacetylation and demethylation at these pluripotency ge
48 genetic regulators necessary for (i) histone deacetylation and demethylation, (ii) binding to methyla
49 ce of conserved active site residues in PNAG deacetylation and demonstrate that the C-terminal domain
50 fication of FoxO3, including early (6 hours) deacetylation and dephosphorylation that coincide with l
51 scriptional gene silencing (TGS) via histone deacetylation and DNA methylation.
52  and NAD(+) supplementation restored protein deacetylation and enhanced oxygen consumption in circadi
53 h the induction of SIRT2, leading to ALDH1A1 deacetylation and enzymatic activation to promote breast
54 last differentiation in part through histone deacetylation and epigenetic suppression of an alternati
55 nucleation region in vivo, promoting histone deacetylation and FLC transcriptional silencing, and int
56 tion repression activity of Tet2 via histone deacetylation and for the prevention of constant transcr
57 ment suppressed the effects of PH on histone deacetylation and hepatocellular bromodeoxyuridine (BrdU
58  activity is largely responsible for histone deacetylation and inflammatory responses of primary micr
59  X receptor (FXR) activity due to persistent deacetylation and lower protein expression that led to d
60           However, the alteration of histone deacetylation and miR-193b-3p and Rad51 expression in re
61 ssion via a dual mechanism involving histone deacetylation and nucleosome remodeling.
62 cystic epithelial cell proliferation through deacetylation and phosphorylation of Rb and regulated cy
63 o SIRT1-mediated p53 and histone 3 lysate 56 deacetylation and results in reduced EC senescence in vi
64 ular iron homeostasis via regulation of NRF2 deacetylation and stability.
65 functional link between SIRT7-mediated H3K18 deacetylation and the maintenance of genome integrity.
66 1 gene transcription through regulating TAF9 deacetylation and transcription factor IID assembly.
67 ression screenings demonstrates that histone deacetylation and transcriptional dysregulation are two
68 dentified a subset of genes in which H3K9,14 deacetylation and transcriptional dysregulation concur.
69 haride composition analysis indicated that N-deacetylation and/or N-desulfation may have taken place.
70 d probes for chitosan (the product of chitin deacetylation) and for demethylesterified homogalacturon
71 ons, acetylated histone 3 on lysine 9 and 14 deacetylation, and acetylated histone 3 on lysine 9 meth
72 cetylases (HDA6 and HDA19), promotes histone deacetylation, and attenuates derepression of genes unde
73 ates a subset of neuronal genes through FOXO deacetylation, and disruption of HDAC3 contributes to co
74 erse modifications: DNA methylation, histone deacetylation, and histone methylation.
75 ehavioral abnormality, chemokinesis, histone deacetylation, and immunity.
76 sed carboxypeptidase activities, increased N-deacetylation, and increased O-acetylation in VRE when g
77 enetically modulate DNA methylation, histone deacetylation, and lysine demethylation.
78 ation-induced PABP1-SIRT1 association, PABP1 deacetylation, and poly(A)RNA nuclear retention.
79 ivity can be modulated by lysine acetylation-deacetylation, and prevention of TopA inactivation from
80  histone deacetylase 6 (HDAC6)-mediated RelA deacetylation, and thus enhances transcriptional activit
81 n activity or affected for histone H4 Lys-16 deacetylation are impaired, at least in part, for telome
82 ing of the HLA class-I APM is due to histone deacetylation as inhibition of histone deacetylases (HDA
83 data reveal that loss of FBP1 due to histone deacetylation associates with poor prognosis of HCC and
84 ha-PLZF recruits HDAC1 and causes histone H3 deacetylation at C/EBPalpha target loci, thereby decreas
85                                       Global deacetylation at low pH is reflected at a genomic level
86       These results suggest that acetylation/deacetylation at Lys-318/Lys-322 is a mode of regulating
87 ranscriptional activity via reciprocal STAT3 deacetylation at Lys685 and phosphorylation at Tyr705.
88 oes not correlate with changes in histone H4 deacetylation at replication forks.
89 ures, in which it binds and triggers histone deacetylation at the promoter of the calbindin gene (Cal
90 etic mechanisms, such as histone acetylation/deacetylation balance, in part via histone deacetylase (
91     On the other hand, inhibition of histone deacetylation by an inhibitor specific to HDACs 1-3, CI-
92 s, and particularly BMAL1-Lys537 acetylation/deacetylation by CLOCK/SIRT1, were shown to be critical
93                       Here we find that Smc3 deacetylation by Hos1 has a more immediate effect in the
94 ohesin association with chromosomes, and its deacetylation by Hos1 in anaphase allows re-use of Smc3
95 on between Hst3 synthesis, genome-wide H3K56 deacetylation by Hst3, and cell cycle-regulated degradat
96             Functionally, preventing histone deacetylation by increasing nucleocytoplasmic acetyl-CoA
97 4 and SAGA as well as stimulating nucleosome deacetylation by multiple HDACs to maintain the proper l
98                   Here, we show that histone deacetylation by NuRD specifies recruitment for Polycomb
99            Fatty acids (FAs) prevented CIDEC deacetylation by promoting the dissociation of CIDEC fro
100 cRNA transcription that targets H3K36me3 and deacetylation by Rpd3S to the mRNA promoter.
101 xO1-dependent and furthermore required FoxO1 deacetylation by the NAD(+)-dependent deacetylase, SirT1
102 ted in the nucleus during starvation through deacetylation by the nuclear deacetylase Sirt1.
103 re, pharmacologically induced SIRT1-mediated deacetylation can attenuate aberrant NEDD4-mediated HSF1
104                      Histone acetylation and deacetylation can be dynamically regulated in response t
105 oumarin enhances the catalytic efficiency of deacetylation catalyzed by cobalt(II)-bound histone deac
106 ation and the deacetylase sirtuin-1-mediated deacetylation coexist to maintain CREBH acetylation stat
107 the Dleu2 promoter via inhibition of histone deacetylation combined with BSAP knockdown increased miR
108  and NuRD (nucleosome remodeling and histone deacetylation) complex in the DNA damage response.
109 f the yeast complex, which we called Histone Deacetylation Complex1 (HDC1).
110 e data suggest that MSI1, HDA19, and HISTONE DEACETYLATION COMPLEX1 protein form a core complex that
111 in a subset of occluded genes, while histone deacetylation contributes to the implementation but not
112 ation, we tested the hypothesis that histone deacetylation contributes to the maintenance of chronic
113 neated a novel pathway through which histone deacetylation could contribute to CORT regulation of GR
114                    Here, we describe protein deacetylation coupled with deacetylimination as a functi
115                         Thus, an acetylation-deacetylation cycle ensures that LC3 effectively redistr
116  controlled in part by a dynamic acetylation/deacetylation cycle.
117                               Loxl3-mediated deacetylation/deacetylimination disrupts Stat3 dimerizat
118 ther LOX family members can catalyze protein deacetylation/deacetylimination.
119 s with different structural features, namely deacetylation degree (5-91%) and molecular weight (24-46
120 e efficiency of reduction increased with the deacetylation degree and applied dose.
121         Results show that chitosan with high deacetylation degrees, including fungal chitosan, which
122 sed that FoxO proteins are activated through deacetylation-dependent nuclear translocation to foresta
123 at mitochondrial GOT2 is acetylated and that deacetylation depends on mitochondrial SIRT3.
124 e expression signature associated with FoxO1 deacetylation differs from wild type by only approximate
125                                         Smc3 deacetylation facilitated removal of cohesins from chrom
126                                              Deacetylation followed by regioselective phosphorylation
127 lterations including histone acetylation and deacetylation has been demonstrated to play an important
128 elbine with plasma revealed that vinorelbine deacetylation in Cyp3a and especially in P-gp/Cyp3a knoc
129 rts a central role of HDA-1-mediated histone deacetylation in heterochromatin spreading and gene sile
130 transcription through HDAC1-mediated histone deacetylation in LPS-induced macrophages, acting as a ne
131 IFICANCE STATEMENT The importance of histone deacetylation in normal brain functions and pathological
132 indicate an important role of SIRT1-mediated deacetylation in regulating the formation of DUBm subcom
133 of differentiation through continual histone deacetylation in stem cells enables self-renewal and rap
134 acetyl-l-Lys (AcK), and subsequent enzymatic deacetylation in the host cell.
135 acts with TRbeta1 in vitro, promotes TRbeta1 deacetylation in the presence of T3 and enhances ubiquit
136  a critical role for histone acetylation and deacetylation in the response of neurons to injury.
137 s of lysine 68 to arginine (K68R), mimicking deacetylation, increased activity.
138 itor) and 4-phenylbutyric acid (PBA, histone deacetylation inhibitor).
139                        This lysozyme-induced deacetylation is dependent upon sigma(V).
140                  Here we report that Lys-148 deacetylation is indispensable for facilitating MORF4L1
141                        We found that tubulin deacetylation is initiated by calcium influx at the site
142  in mouse tumor models demonstrate that PKM2 deacetylation is integral to SIRT6-mediated tumor suppre
143 fied new targets of Sir2 and tested if their deacetylation is necessary for Clr4-mediated heterochrom
144 acological inhibition of SIRT2-dependent p53 deacetylation is of great therapeutic interest for the t
145 muscle revealed that a major target of Sirt3 deacetylation is the E1alpha subunit of PDH (PDH E1alpha
146  as a rate-limiting component of the histone deacetylation machinery and as an attractive tool for in
147 s of affected proteins, aberrant acetylation/deacetylation may contribute to disease states.
148 at local competition between acetylation and deacetylation may play a critical role in the resolution
149                           SlAacS acetylation/deacetylation may represent a conserved mechanism for re
150 genetic changes to active chromatin, such as deacetylation, may be mediated by HDAC3 in dying neurons
151 e 1479 (K1479) and stimulates INa via lysine-deacetylation-mediated trafficking of Nav1.5 to the plas
152                          Overexpression of a deacetylation-mimetic version of OPA1 recovered the mito
153 ess phosphorylation than the WT enzyme and a deacetylation-mimicking mutant (K72R).
154 show that the Mbd3/nucleosome remodeling and deacetylation (NuRD) chromatin remodeling complex oppose
155 tions by forming a nucleosome remodeling and deacetylation (NuRD) complex that regulates transcriptio
156 cruits the nucleosome remodeling and histone deacetylation (NuRD) complex to damaged chromatin.
157                    Nucleosome remodeling and deacetylation (NuRD) complexes are co-transcriptional re
158                                      Histone deacetylation occurred after transcriptional repression.
159 s the site where fasting-induced acetylation/deacetylation occurs.
160 ease, it was shown that AnCDA catalyses mono-deacetylation of (GlcNAc)2 and full deacetylation of (Gl
161 ses mono-deacetylation of (GlcNAc)2 and full deacetylation of (GlcNAc)3-6 in a non-processive manner.
162 ninvasive real-time progression assay, where deacetylation of a p53 based peptide was observed by nuc
163  summary, our results show that TH-dependent deacetylation of a second metabolically regulated transc
164                         Sirtuins can promote deacetylation of a wide range of substrates in diverse c
165                                   We blocked deacetylation of ac-SMC3 using an HDAC8-specific inhibit
166        Histone deacetylases (HDACs) catalyze deacetylation of acetyl-lysine residues within proteins.
167 ic catalysis, and assays that measured SIRT2 deacetylation of acetylated alpha-tubulin revealed that
168 se family comprises 18 enzymes that catalyze deacetylation of acetylated lysine residues; however, th
169  ERK/HDAC6-mediated cell motility is through deacetylation of alpha-tubulin.
170 orylates HDAC6 to promote cell migration via deacetylation of alpha-tubulin.
171 tes HDAC6, thereby increasing HDAC6-mediated deacetylation of alpha-tubulin.
172 osis, and tumorigenesis, and its role in the deacetylation of APE1 after genotoxic stress.
173                                              Deacetylation of Bcl6 is required for its transcriptiona
174 s that respond to replication stress through deacetylation of CDK9, providing insight into how SIRT2
175  cell (mESC) differentiation in part through deacetylation of cellular retinoic acid binding protein
176 ates mitochondrial ceramide biosynthesis via deacetylation of ceramide synthase (CerS) 1, 2, and 6.
177  hypothesis that IR triggers SIRT3-dependent deacetylation of ceramide synthases and the elevation of
178 /reperfusion (IR) showed that SIRT3-mediated deacetylation of ceramide synthases increased enzyme act
179 e biotinyl-lysine method was used to compare deacetylation of chemically acetylated histones by the y
180 t evolutionarily conserved sites disrupt its deacetylation of DNA-damage response proteins by impairi
181 formation regulation 2 homolog 1) levels and deacetylation of FOXO1 (forkhead box O1).
182                                              Deacetylation of FOXO3 by SIRT activation or SIRT1 or SI
183 utophagy-related genes, likely via increased deacetylation of FoxO3a.
184 hese findings demonstrate that Sirt1-induced deacetylation of FoxOs unleashes Wnt signaling.
185 cle where Hst3 normally mediates genome-wide deacetylation of H3K56.
186 T2 regulates H4K20me1 deposition through the deacetylation of H4K16Ac (acetylation of H4K16) and dete
187  EMT is accompanied by rapid HDAC6-dependent deacetylation of heat shock protein 90 (HSP90).
188     Specifically, these inhibitors limit the deacetylation of heat shock protein 90, resulting in les
189                                Specifically, deacetylation of histone 3 at lysine 9 (H3K9), through t
190 ression and other cellular functions through deacetylation of histone and nonhistone proteins.
191 enhancer-promoter communication and prompted deacetylation of histone H3 in the HNF4alpha P1 promoter
192 tion triggered by H3 S10 phosphorylation and deacetylation of histone H4 promote short-range compacti
193 istone H4 tails and antagonize Sir2-mediated deacetylation of histone H4K16.
194 alization of N-CoR/HDAC3, thereby inhibiting deacetylation of histones and HDAC4 client transcription
195 ges common in wild-type cells, including the deacetylation of histones, formation of heterochromatin,
196 t to regulatory changes including epigenetic deacetylation of histones.
197 anistic insights into the understanding that deacetylation of HSPA5 by HDAC6 facilitates GP78-mediate
198 nes, and this effect is largely dependent on deacetylation of IDH2 and SOD2.
199 d recruitment of SIRT1 activity promotes the deacetylation of individual SAGA complex components.
200 ts ability to promote cell migration through deacetylation of its cytoplasmic substrates such as alph
201                                              Deacetylation of LC3 at K49 and K51 by Sirt1 allows LC3
202 he C-terminal domain is required for maximal deacetylation of longer PNAG oligomers.
203             Specifically, LRRK2 promoted the deacetylation of Lys-5 and Lys-12 on histone H4, causing
204 ns, we asked whether in vitro acetylation or deacetylation of lysine 40 (K40), a major posttranslatio
205 nspired by the posttranslational acetylation/deacetylation of lysine residues, in which a protein enc
206 g effects of Sirt1 evidently result from the deacetylation of many transcription factors and co-facto
207           This release correlates with rapid deacetylation of matrix proteins, and SIRT3 is required
208 phy and doxorubicin (Dox)-cardiotoxicity via deacetylation of mitochondrial proteins.
209 nts but, rather, occurred via SIRT3-mediated deacetylation of mitochondrial SOD2, leading to SOD2 act
210                              HDAC2-dependent deacetylation of MORF4L1 enhances MORF4L1 homodimerizati
211 rtuins (SIRTs) catalyze the NAD(+)-dependent deacetylation of N(epsilon)-acetyl lysines on various pr
212 orms together with a close homolog HDAC2, is deacetylation of new histone H4 deposited at replication
213  of MSCs at least in part through inhibition/deacetylation of NF-kappaB and activation of Sox9.
214 ytes and that puerarin led to SIRT1-mediated deacetylation of NF-kappaB and suppression of NOX4 expre
215                We tested the hypothesis that deacetylation of nucleosomal histones associated with ab
216 interaction of HDAC1 and p53 resulted in the deacetylation of p53 and suppression of Bmf expression i
217                            Consequently, the deacetylation of p53 reduces the transcription of a spec
218                                      Because deacetylation of p53 regulates its effect on apoptosis,
219   Collectively, these observations show that deacetylation of p53 suppresses Bmf expression and facil
220 gulated cystic epithelial cell death through deacetylation of p53.
221 iplasm and that this may allow for efficient deacetylation of PEL before its export from the cell.
222     The K m and k cat of AnCDA for the first deacetylation of penta-N-acetyl-chitopentaose are 72 mic
223 ore and potent activation of Sirt6-dependent deacetylation of peptide substrates and complete nucleos
224 of SIRT1, resulting in FGF21/SIRT1-dependent deacetylation of PGC-1alpha and induction of the brownin
225 DAC3 coactivation of ERRalpha is mediated by deacetylation of PGC-1alpha and is required for the tran
226 irement of a C-terminal domain for efficient deacetylation of PNAG in Gram-negative species.
227                                      Partial deacetylation of polysaccharides caused compensatory up-
228       The two-stage nitration and subsequent deacetylation of readily available 1,3-dicarbonyl compou
229 sensing activity and that the HDAC6-mediated deacetylation of RIG-I is critical for viral RNA detecti
230 rough histone deacetylase 6 (HDAC6)-mediated deacetylation of RNA-binding protein Sam68 (Src-associat
231                         In vitro acetylation/deacetylation of SacAcsA enzyme was studied by Western b
232 esents detailed kinetics for HDAC8-catalyzed deacetylation of singly-acetylated, full-length protein
233 ncreased SirT-1 protein levels and increased deacetylation of SirT-1 targets involved in DNA repair.
234 CAR2), which binds to SirT1 and inhibits the deacetylation of substrates.
235  HDAC1 activates PU.1 gene transcription via deacetylation of TATA-binding protein-associated factor
236  HDAC9 promoter by DNMT3a, along with lysine deacetylation of TBK1 by HDAC9, are essential events dur
237          We demonstrate that HDAC8 catalyzes deacetylation of tetrameric histone (H3/H4) substrates w
238  the reducing end sugar was much slower than deacetylation of the other sugars in chito-oligomers.
239 ne gene expression on IL-4-moDCs through the deacetylation of the promoters of these genes, leading t
240                                              Deacetylation of the reducing end sugar was much slower
241         SKI controls histone acetylation and deacetylation of the Rorc locus and TH17 cell differenti
242 may alter the preproPC2 gene directly or via deacetylation of the transcription factor Forkhead box p
243 d HDAC-3/5/7 with myocyte enhancer factor-2; deacetylation of these factors led to down-regulation of
244  6 (HDAC6) as the enzyme responsible for the deacetylation of these residues, and provide proof of co
245 on of the DNA damage response prevents SIRT1 deacetylation of TopBP1, resulting in a switch from DNA
246            SIRT1 regulates transcription via deacetylation of transcription factors such as PPARgamma
247 ted step in the biosynthesis of lipid A, the deacetylation of uridyldiphospho-3-O-(R-hydroxydecanoyl)
248 ion of enzymes that regulate acetylation and deacetylation offers much potential for inhibiting cance
249 ffects of resveratrol, SIRT1, and PGC-1alpha deacetylation on mitochondrial biogenesis in muscle.
250    BpsB displays metal- and length-dependent deacetylation on poly-beta-1,6-N-acetyl-d-glucosamine (P
251 miR-193b-3p expression was caused by histone deacetylation on the miR-193b-3p promoter in the HepG2 c
252  Additionally, TH was unable to induce FoxO1 deacetylation or hepatic PCK1 gene expression in TH rece
253 ric DNA, but not by DNA methylation, histone deacetylation, or histone trimethylation at telomeres an
254                As a result of SIRT6-mediated deacetylation, PKM2 nuclear protein kinase and transcrip
255    These results indicate that peptidoglycan deacetylation plays an important role in modulating host
256 lation at the promoter, H2Bubi initiates the deacetylation process, which decreases chromatin remodel
257 d that the cAMP pathway participates in this deacetylation process.
258 PP/p25 counteracts the SIRT2-derived tubulin deacetylation producing enhanced microtubule acetylation
259 ypothesis where the acetate byproduct of the deacetylation reaction escapes via the 14 A internal cav
260 ucture of an LpxC enzyme in complex with the deacetylation reaction product, UDP-(3-O-(R-3-hydroxymyr
261 specificity a conserved Pro, shares with the deacetylation reaction the same active site and one cata
262 , cyclophilin D, and Hsp10, and analyzed the deacetylation reaction.
263 ghly coordinated methylation and acetylation/deacetylation reactions.
264 to regulate gene transcription by catalyzing deacetylation reactions.
265                                      Histone deacetylation regulates gene expression during plant str
266 n of H3K4 and consequent promoter nucleosome deacetylation repress ste11 induction and cell different
267 anscription via modulation of H3 acetylation/deacetylation, respectively, through competition for bin
268 SIK2 kinase activity, whereas HDAC6-mediated deacetylation restores the activity.
269 that are involved in histone acetylation and deacetylation result in multiple congenital anomalies wi
270          Surprisingly, inhibition of histone deacetylation resulted in a 50-80% reduction in EGFRvIII
271 tion by p300 overexpression or inhibition of deacetylation resulted in increases of Ser-294 phosphory
272                               SIRT6-mediated deacetylation results in PKM2 nuclear export.
273 ylase, interacts with and keeps MORF4L1 in a deacetylation status at Lys(148) that triggers MORF4L1 s
274       In turn, HDAC9 directly maintained the deacetylation status of the key PRR signaling molecule T
275 mophore maturation, and is also an efficient deacetylation substrate for sirtuins.
276 in the range of 8-35 muM and increased H4K16 deacetylation, suggesting a possible role for SIRT1 acti
277 modulated in distinct fashion by acetylation/deacetylation, suggesting an integrated regulation mecha
278                     SirT1 also promotes DBC1 deacetylation, suggesting the presence of a negative-fee
279                                         This deacetylation/SUMOylation switch is governed by an unusu
280 ruitment of HDAC4 by SIRT1 which permits the deacetylation/SUMOylation switch of HIC1.
281 tivity that is coordinated by an acetylation-deacetylation switch, p300/CBP-mediated Lys-53 acetylati
282               To date, bacterial acetylation/deacetylation systems have been studied in a few bacteri
283 ture models, we identified a candidate SIRT2 deacetylation target at PKM2 lysine 305 (K305).
284 concert with enrichment of H4K16ac (itself a deacetylation target of SIRT1), which is associated with
285 -chain acyl-CoA dehydrogenase, a known SIRT3 deacetylation target; improved fatty acid beta-oxidation
286          Whereas SIRT1 exhibits diversity in deacetylation targets and subcellular localization, SIRT
287   beta-Chitin was more susceptible to alkali deacetylation than was alpha-chitin, and required a lowe
288 e genome-wide waves of H3K56 acetylation and deacetylation that occur during each cell cycle.
289 on/de-ubiquitination and histone acetylation/deacetylation, the repressive histone methyl transferase
290 on by inhibiting SIRT1-mediated beta-catenin deacetylation, thereby enhancing LEF1-beta-catenin compl
291 ther highlighting the contribution of LRP130 deacetylation to increased OXPHOS in fasted liver.
292 umerous transcription factors in response to deacetylation to promote mitochondrial biogenesis and ox
293 w that the RIG-I C-terminal region undergoes deacetylation to regulate its viral RNA-sensing activity
294                        Insulin promotes K220 deacetylation to stimulate PGK1 activity.
295  cohesion in early anaphase; subsequent Smc3 deacetylation, triggered by Scc1 cleavage, is also requi
296          These analyses place Sir2 and H3K14 deacetylation upstream of Clr4 recruitment during hetero
297                                The degree of deacetylation was calculated by potentiometric titration
298 tion of proinflammatory cytokines, partial N-deacetylation was carried out by hydrazinolysis.
299 sms, including histone modifications such as deacetylation, we tested the hypothesis that histone dea
300                                              Deacetylation with recombinant SIRT3 partially restored

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